Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(15S)-prostaglandin E2
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 PubChem ID
CID: 5280360
SID: 99431525
Canonical SMILES
CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
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Compound Formula C20H32O5
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E2 receptor EP3 subtype
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
P43115
Gene Name
PTGER3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000064 Chem-1
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
IC50 < 3 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 2.5 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 0.33 nM
   TI
   LI
   LO
   TS
2
Ki = 2.17 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.94 nM
2 Ki = 0.33 nM
3 Ki = 5 nM