Brief Information of the Compound and Protein
Compound Name
6-(8-fluoro-2-naphthyl)-3-(2-methyl-1-oxazol-2-yl-propyl)-1H-pyridin-2-one
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Canonical SMILES
CC(C)C(c1ncco1)c1ccc(-c2ccc3cccc(F)c3c2)[nH]c1=O
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Compound Formula C22H19FN2O2
Compound Structure
Protein Name
Prostaglandin E2 receptor EP3 subtype
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
P43115
Gene Name
PTGER3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 64 nM
   TI
   LI
   LO
   TS
2
Ki = 24 nM
   TI
   LI
   LO
   TS