Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT01013 , C-X-C chemokine receptor type 2
Gene Name CXCR2
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P25025
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT01013
 
Compound ID Compound Name Compound Formula
CP0444705
(R)-2-hydroxy-3-(2-(1-(4-isopropylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-N,N-dimethylbenzamide
   Show/Hide
C23H27N3O5
 2
1
IC50 = 1.3 nM
   TI
   LI
   LO
   TS
2
Ki = 1 nM
   TI
   LI
   LO
   TS
CP0845753
3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C19H17N3O4
 2
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
2
IC50 = 26 nM
   TI
   LI
   LO
   TS
CP0861701
5-chloro-3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C19H16ClN3O4
 1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
CP0924832
4-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-3-hydroxybenzonitrile
   Show/Hide
C17H11N3O3
 2
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
2
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0464255
3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino}-6-fluoro-2-hydroxy-N,N-dimethylbenzenesulfonamide
   Show/Hide
C16H15BrFN5O3S
 1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
CP0427078
3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino}-6-chloro-2-hydroxy-N,N-dimethylbenzenesulfonamide
   Show/Hide
C16H15BrClN5O3S
 1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
CP0917519
3-(3,4-dioxo-2-(pentan-3-ylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C18H23N3O4
 2
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
2
IC50 = 19.1 nM
   TI
   LI
   LO
   TS
CP0378831
3-(2-bromophenyl)-2-cyano-1-(2-hydroxy-4-methyl-3-{[3-(morpholin-4-yl)pentan-3-yl]sulfamoyl}phenyl)guanidine
   Show/Hide
C24H31BrN6O4S
 1
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
CP0498665
2-[(2,3-difluorophenyl)methylsulfanyl]-4-[(1S,2S)-2-(hydroxymethyl)cyclopropyl]-6-oxo-1H-pyrimidine-5-carbonitrile
   Show/Hide
C16H13F2N3O2S
 1
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
CP0394699
3-[3-(2-Bromo-phenyl)-ureido]-6-chloro-2-hydroxy-benzenesulfonamide
   Show/Hide
C13H11BrClN3O4S
 1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
CP0378832
3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino}-2-hydroxy-N,N,6-trimethylbenzenesulfonamide
   Show/Hide
C17H18BrN5O3S
 1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
CP0383548
3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino}-2-hydroxy-N,N-dimethyl-6-(trifluoromethyl)benzenesulfonamide
   Show/Hide
C17H15BrF3N5O3S
 1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
CP0550905
(1S,2S)-2-[5-cyano-2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-1H-pyrimidin-4-yl]cyclopropane-1-carboxamide
   Show/Hide
C16H12F2N4O2S
 1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
CP0565512
6-chloro-3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxy-N-(2-methoxyethyl)benzenesulfonamide
   Show/Hide
C19H18ClN3O6S
 1
1
IC50 = 8 nM
   TI
   LI
   LO
   TS
CP0915922
3-[4-chloro-3-(4-ethyl-piperazine-1-sulfonyl)-2-hydroxy-phenylamino]-4-(2-propyl-phenylamino)-cyclobut-3-ene-1,2-dione trifluoro-acetic acid salt
   Show/Hide
C27H30ClF3N4O7S
 1
1
IC50 = 8 nM
   TI
   LI
   LO
   TS
CP0910930
3-(2-(cyclopentylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C18H21N3O4
 2
1
IC50 = 8 nM
   TI
   LI
   LO
   TS
2
IC50 = 144.8 nM
   TI
   LI
   LO
   TS
CP0383549
3-(2-bromophenyl)-1-[4-chloro-3-({3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pentan-3-yl}sulfamoyl)-2-hydroxyphenyl]-2-cyanoguanidine
   Show/Hide
C25H32BrClN6O4S
 1
1
IC50 = 9 nM
   TI
   LI
   LO
   TS
CP0464257
3-[2-(benzyloxy)phenyl]-1-[4-chloro-3-(dimethylsulfamoyl)-2-hydroxyphenyl]-2-cyanoguanidine
   Show/Hide
C23H22ClN5O4S
 1
1
IC50 = 9 nM
   TI
   LI
   LO
   TS
CP0486903
6-chloro-3-({(cyanoimino)[(2-fluorophenyl)amino]methyl}amino)-2-hydroxy-N,N-dimethylbenzenesulfonamide
   Show/Hide
C16H15ClFN5O3S
 1
1
IC50 = 9 nM
   TI
   LI
   LO
   TS
CP0496884
3-[3-(2-Bromo-phenyl)-ureido]-6-chloro-2-hydroxy-benzamide
   Show/Hide
C14H11BrClN3O3
 1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
CP0844753
3-(2-bromophenylamino)-4-(4-chloro-2-hydroxy-3-(4-methyl-1,4-diazepan-1-ylsulfonyl)phenylamino)cyclobut-3-ene-1,2-dione hydrochloride
   Show/Hide
C22H23BrCl2N4O5S
 1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
CP0955021
3-(2-(cyclohexylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C19H23N3O4
 1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
CP0955683
2-hydroxy-3-(2-(isopropylamino)-3,4-dioxocyclobut-1-enylamino)-N,N-dimethylbenzamide
   Show/Hide
C16H19N3O4
 1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
CP0410626
(1S,2S)-2-[5-cyano-2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-1H-pyrimidin-4-yl]cyclopropane-1-carboxylic acid
   Show/Hide
C16H11F2N3O3S
 1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
CP0439048
3-[3-(2-Bromo-phenyl)-ureido]-6-chloro-2-hydroxy-N,N-dimethyl-benzenesulfonamide
   Show/Hide
C15H15BrClN3O4S
 1
1
IC50 = 12 nM
   TI
   LI
   LO
   TS
CP0383550
3-(2-bromophenyl)-2-cyano-1-(2-hydroxy-3-{[3-(morpholin-4-yl)pentan-3-yl]sulfamoyl}phenyl)guanidine
   Show/Hide
C23H29BrN6O4S
 1
1
IC50 = 12 nM
   TI
   LI
   LO
   TS
CP0486902
6-chloro-3-[((cyanoimino){[2-(trifluoromethyl)phenyl]amino}methyl)amino]-2-hydroxy-N,N-dimethylbenzenesulfonamide
   Show/Hide
C17H15ClF3N5O3S
 1
1
IC50 = 12 nM
   TI
   LI
   LO
   TS
CP0918672
3-(2-bromo-phenylamino)-4-[4-fluoro-2-hydroxy-3-(4-methyl-piperazine-1-sulfonyl)-phenylamino]-cyclobut-3-ene-1,2-dione trifluoro-acetic acid salt
   Show/Hide
C23H21BrF4N4O7S
 1
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
CP0464254
1-[4-chloro-3-(dimethylsulfamoyl)-2-hydroxyphenyl]-2-cyano-3-(2-phenylphenyl)guanidine
   Show/Hide
C22H20ClN5O3S
 1
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
CP0526490
6-chloro-3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxybenzamide
   Show/Hide
C17H12ClN3O4
 1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
CP0955684
3-(2-(tert-butylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C17H21N3O4
 1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
CP0501838
3-(2-(o-toluidino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N,6-trimethylbenzenesulfonamide
   Show/Hide
C20H21N3O5S
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0464256
6-chloro-3-({(cyanoimino)[(2-ethylphenyl)amino]methyl}amino)-2-hydroxy-N,N-dimethylbenzenesulfonamide
   Show/Hide
C18H20ClN5O3S
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0524530
(R)-1-(3-(3-(3-(2-bromophenyl)-2-cyanoguanidino)-6-chloro-2-hydroxyphenylsulfonamido)pentan-3-yl)pyrrolidine-2-carboxylic acid
   Show/Hide
C24H28BrClN6O5S
 1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
CP0399972
1-[4-chloro-3-({3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pentan-3-yl}sulfamoyl)-2-hydroxyphenyl]-2-cyano-3-(2-methylphenyl)guanidine
   Show/Hide
C26H35ClN6O4S
 1
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
CP0427088
6-chloro-3-({(cyanoimino)[(2-methylphenyl)amino]methyl}amino)-2-hydroxy-N,N-dimethylbenzenesulfonamide
   Show/Hide
C17H18ClN5O3S
 1
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
CP0873266
3-(4-chloro-2-hydroxy-3-(4-(piperidin-1-yl)piperidin-1-ylsulfonyl)phenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione hydrochloride
   Show/Hide
C26H30Cl2N4O5S
 1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
CP0920871
3-(4-chloro-2-hydroxy-3-(4-methyl-1,4-diazepan-1-ylsulfonyl)phenylamino)-4-(2-chlorophenylamino)cyclobut-3-ene-1,2-dione hydrochloride
   Show/Hide
C22H23Cl3N4O5S
 1
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
CP0068783
1-(2-bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea
   Show/Hide
C13H10BrN3O4
 1
1
IC50 = 22 nM
   TI
   LI
   LO
   TS
CP0853168
3-(2-hydroxy-4-nitrophenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
   Show/Hide
C16H11N3O5
 2
1
IC50 = 22 nM
   TI
   LI
   LO
   TS
2
IC50 = 36 nM
   TI
   LI
   LO
   TS
CP0432840
1-(3-{[3-(4-aminopiperidin-1-yl)pentan-3-yl]sulfamoyl}-4-chloro-2-hydroxyphenyl)-3-(2-bromophenyl)-2-cyanoguanidine
   Show/Hide
C24H31BrClN7O3S
 1
1
IC50 = 22 nM
   TI
   LI
   LO
   TS
CP0846916
3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxy-N-methylbenzamide
   Show/Hide
C18H15N3O4
 1
1
IC50 = 22 nM
   TI
   LI
   LO
   TS
CP0565508
1-(2-Bromo-phenyl)-3-(4-cyano-2-hydroxy-phenyl)-urea
   Show/Hide
C14H10BrN3O2
 1
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
CP0373706
3-(2-bromo-phenylamino)-7-nitro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C13H9BrN4O5S
 1
1
IC50 = 26 nM
   TI
   LI
   LO
   TS
CP0939748
3-[2-hydroxy-3-(4-methyl-piperazine-1-carbonyl)-phenylamino]-4-phenylamino-cyclobut-3-ene-1,2-dione trifluoro-acetic acid salt
   Show/Hide
C24H23F3N4O6
 1
1
IC50 = 27 nM
   TI
   LI
   LO
   TS
CP0471390
3-(2-bromophenylamino)-4-(4-chloro-2-hydroxy-3-(pyrrolidine-1-carbonyl)phenylamino)cyclobut-3-ene-1,2-dione
   Show/Hide
C21H17BrClN3O4
 1
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
CP0383551
6-chloro-3-{[[(3-chloro-2-fluorophenyl)amino](cyanoimino)methyl]amino}-2-hydroxy-N,N-dimethylbenzenesulfonamide
   Show/Hide
C16H14Cl2FN5O3S
 1
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
CP0464799
3-(2-bromophenylamino)-4-(4-chloro-2-hydroxyphenylamino)cyclobut-3-ene-1,2-dione
   Show/Hide
C16H10BrClN2O3
 1
1
IC50 = 32 nM
   TI
   LI
   LO
   TS
CP0495784
3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxybenzonitrile
   Show/Hide
C17H11N3O3
 1
1
IC50 = 32 nM
   TI
   LI
   LO
   TS
CP0869605
3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxybenzamide
   Show/Hide
C17H13N3O4
 1
1
IC50 = 34 nM
   TI
   LI
   LO
   TS
CP0372182
3-(2-bromophenylamino)-4-(2-hydroxy-4-nitrophenylamino)cyclobut-3-ene-1,2-dione
   Show/Hide
C16H10BrN3O5
 1
1
IC50 = 37 nM
   TI
   LI
   LO
   TS
CP0367896
4-cyclopropyl-2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-1H-pyrimidine-5-carbonitrile
   Show/Hide
C15H11F2N3OS
 2
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
2
IC50 = 140 nM
   TI
   LI
   LO
   TS
CP0955022
3-(2-(furan-2-ylmethylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C18H17N3O5
 1
1
IC50 = 41 nM
   TI
   LI
   LO
   TS
CP0939747
3-[2-hydroxy-3-(4-methyl-[1,4]diazepane-1-carbonyl)-phenylamino]-4-phenylamino-cyclobut-3-ene-1,2-dione trifluoro-acetic acid salt
   Show/Hide
C25H25F3N4O6
 1
1
IC50 = 44 nM
   TI
   LI
   LO
   TS
CP0096177
3-(2-(2,2-diethylhydrazinyl)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C17H22N4O4
 1
1
IC50 = 46 nM
   TI
   LI
   LO
   TS
CP0490412
3-(2-bromophenylamino)-4-(2-hydroxyphenylamino)cyclobut-3-ene-1,2-dione
   Show/Hide
C16H11BrN2O3
 1
1
IC50 = 51 nM
   TI
   LI
   LO
   TS
CP0371764
3-(5-chloro-2-hydroxy-4-nitrophenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
   Show/Hide
C16H10ClN3O5
 1
1
IC50 = 52 nM
   TI
   LI
   LO
   TS
CP0960672
methyl 3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxybenzoate
   Show/Hide
C18H14N2O5
 1
1
IC50 = 53 nM
   TI
   LI
   LO
   TS
CP0490402
3-(5-chloro-2-hydroxyphenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
   Show/Hide
C16H11ClN2O3
 1
1
IC50 = 54 nM
   TI
   LI
   LO
   TS
CP0104331
7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C19H14N4O6S
 1
1
IC50 = 54 nM
   TI
   LI
   LO
   TS
CP0373708
7-chloro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C19H14ClN3O4S
 1
1
IC50 = 54 nM
   TI
   LI
   LO
   TS
CP0492268
3-(2-(2-ethyl-2-phenylhydrazinyl)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C21H22N4O4
 1
1
IC50 = 54 nM
   TI
   LI
   LO
   TS
CP0960671
3-(2-hydroxy-5-nitrophenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
   Show/Hide
C16H11N3O5
 1
1
IC50 = 56 nM
   TI
   LI
   LO
   TS
CP0500777
1-(2-Bromo-phenyl)-3-(3,4-dichloro-2-hydroxy-phenyl)-urea
   Show/Hide
C13H9BrCl2N2O2
 1
1
IC50 = 63 nM
   TI
   LI
   LO
   TS
CP0373671
7-chloro-3-(2-chloro-3-fluoro-phenylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C13H8Cl2FN3O3S
 1
1
IC50 = 64 nM
   TI
   LI
   LO
   TS
CP0373709
3-(2-bromo-phenylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C13H9BrClN3O3S
 1
1
IC50 = 64 nM
   TI
   LI
   LO
   TS
CP0960673
3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-N-ethyl-2-hydroxybenzamide
   Show/Hide
C19H17N3O4
 1
1
IC50 = 65 nM
   TI
   LI
   LO
   TS
CP0524363
7-bromo-3-(2-bromo-phenylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C13H9Br2N3O3S
 1
1
IC50 = 70 nM
   TI
   LI
   LO
   TS
CP0910929
3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-4-hydroxybenzonitrile
   Show/Hide
C17H11N3O3
 1
1
IC50 = 74 nM
   TI
   LI
   LO
   TS
CP0374039
3-(2-(2-ethyl-2-(pyridin-2-yl)hydrazinyl)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C20H21N5O4
 1
1
IC50 = 75 nM
   TI
   LI
   LO
   TS
CP0156021
3-(2-chloro-phenylamino)-7-nitro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C13H9ClN4O5S
 1
1
IC50 = 81 nM
   TI
   LI
   LO
   TS
CP0405627
7-chloro-3-(2-chloro-phenylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C13H9Cl2N3O3S
 1
1
IC50 = 92 nM
   TI
   LI
   LO
   TS
CP0501544
3-(2-(2-ethyl-2-(4-methoxyphenyl)hydrazinyl)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C22H24N4O5
 1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
CP0462351
1-[4-chloro-3-(dimethylsulfamoyl)-2-hydroxyphenyl]-2-cyano-3-[2-(propan-2-yl)phenyl]guanidine
   Show/Hide
C19H22ClN5O3S
 1
1
IC50 = 112 nM
   TI
   LI
   LO
   TS
CP0918015
1-(3-Aminomethyl-4-chloro-2-hydroxy-phenyl)-3-(2-bromo-phenyl)-urea hydrochloride
   Show/Hide
C14H14BrCl2N3O2
 1
1
IC50 = 114 nM
   TI
   LI
   LO
   TS
CP0405621
3-(2-bromo-4-fluoro-phenylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C13H8BrClFN3O3S
 1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
CP0950933
N-benzyl-3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxybenzamide
   Show/Hide
C24H19N3O4
 1
1
IC50 = 139 nM
   TI
   LI
   LO
   TS
CP0413175
5-[(2,3-difluorophenyl)sulfanylmethyl]-2-(furan-2-yl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C17H11F2N3O2S
 1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
CP0960675
3-(3,4-dioxo-2-(tetrahydro-2H-pyran-4-ylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C18H21N3O5
 1
1
IC50 = 171 nM
   TI
   LI
   LO
   TS
CP0495786
1-(4-Cyano-2-hydroxy-phenyl)-3-phenyl-urea
   Show/Hide
C14H11N3O2
 1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
CP0526491
3-(2-hydroxy-4-methylphenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
   Show/Hide
C17H14N2O3
 1
1
IC50 = 205 nM
   TI
   LI
   LO
   TS
CP0405620
3-(biphenyl-2-ylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C19H14ClN3O3S
 1
1
IC50 = 230 nM
   TI
   LI
   LO
   TS
CP0897845
3-(2-hydroxyphenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
   Show/Hide
C16H12N2O3
 2
1
IC50 = 235 nM
   TI
   LI
   LO
   TS
2
IC50 = 476 nM
   TI
   LI
   LO
   TS
CP0458373
7-chloro-3-(2-methoxy-phenylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C14H12ClN3O4S
 1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
CP0473432
2-[(2,3-difluorophenyl)sulfanylmethyl]-6H-pyrimido[1,2-b]indazol-4-one
   Show/Hide
C17H11F2N3OS
 1
1
IC50 = 260 nM
   TI
   LI
   LO
   TS
CP0464798
1-(3-cyano-2-hydroxyphenyl)-3-phenylurea
   Show/Hide
C14H11N3O2
 1
1
IC50 = 276 nM
   TI
   LI
   LO
   TS
CP0458376
3-(2-bromo-phenylamino)-7-methyl-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C14H12BrN3O3S
 1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS
CP0436080
5-[(2,3-difluorophenyl)sulfanylmethyl]-2-pyridin-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C18H12F2N4OS
 1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS
CP0372183
3-(2-hydroxy-5-methylphenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
   Show/Hide
C17H14N2O3
 1
1
IC50 = 308 nM
   TI
   LI
   LO
   TS
CP0495785
1-(2-Hydroxy-4-nitro-phenyl)-3-phenyl-urea
   Show/Hide
C13H11N3O4
 1
1
IC50 = 320 nM
   TI
   LI
   LO
   TS
CP0515396
4-cyclopropyl-2-[(2,3-difluorophenyl)methylsulfanyl]-1H-pyrimidin-6-one
   Show/Hide
C14H12F2N2OS
 1
1
IC50 = 320 nM
   TI
   LI
   LO
   TS
CP0519744
2-benzyl-5-[(2,3-difluorophenyl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C19H14F2N4OS
 2
1
IC50 = 330 nM
   TI
   LI
   LO
   TS
2
IC50 = 350 nM
   TI
   LI
   LO
   TS
CP0372185
3-(2-hydroxy-6-nitrophenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
   Show/Hide
C16H11N3O5
 1
1
IC50 = 358 nM
   TI
   LI
   LO
   TS
CP0524364
3-(2-bromo-phenylamino)-7-fluoro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C13H9BrFN3O3S
 1
1
IC50 = 360 nM
   TI
   LI
   LO
   TS
CP0541617
7-chloro-1,1-dioxo-3-o-tolylamino-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C14H12ClN3O3S
 1
1
IC50 = 390 nM
   TI
   LI
   LO
   TS
CP0414918
5-[(2,3-difluorophenyl)sulfanylmethyl]-2-(2-phenylethyl)-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C20H16F2N4OS
 1
1
IC50 = 470 nM
   TI
   LI
   LO
   TS
CP0373672
3-(2-bromo-phenylamino)-8-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C13H9BrClN3O3S
 1
1
IC50 = 480 nM
   TI
   LI
   LO
   TS
CP0458443
2-cyclohexyl-5-[(2,3-difluorophenyl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C18H18F2N4OS
 1
1
IC50 = 510 nM
   TI
   LI
   LO
   TS
CP0550906
2-benzylsulfanyl-4-cyclopropyl-6-oxo-1H-pyrimidine-5-carbonitrile
   Show/Hide
C15H13N3OS
 1
1
IC50 = 510 nM
   TI
   LI
   LO
   TS
CP0846917
(R)-3-(2-(2,3-dihydro-1H-inden-1-ylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C22H21N3O4
 1
1
IC50 = 548 nM
   TI
   LI
   LO
   TS
CP0418239
2-[(2,3-difluorophenyl)methylsulfanyl]-4-(4-methoxyphenyl)-6-oxo-1H-pyrimidine-5-carbonitrile
   Show/Hide
C19H13F2N3O2S
 1
1
IC50 = 710 nM
   TI
   LI
   LO
   TS
CP0456716
7-chloro-3-(2-fluoro-phenylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C13H9ClFN3O3S
 1
1
IC50 = 740 nM
   TI
   LI
   LO
   TS
CP0489385
2-[(2,3-difluorophenyl)methylsulfanyl]-4-(4-hydroxyphenyl)-6-oxo-1H-pyrimidine-5-carbonitrile
   Show/Hide
C18H11F2N3O2S
 1
1
IC50 = 780 nM
   TI
   LI
   LO
   TS
CP0521703
5-[(2,3-difluorophenyl)sulfanylmethyl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C13H9F2N3OS
 1
1
IC50 = 810 nM
   TI
   LI
   LO
   TS
CP0517993
2-benzyl-5-(phenylsulfanylmethyl)-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C19H16N4OS
 1
1
IC50 = 820 nM
   TI
   LI
   LO
   TS
CP0538400
7-chloro-1,1-dioxo-3-(2-trifluoromethyl-phenylamino)-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C14H9ClF3N3O3S
 1
1
IC50 = 830 nM
   TI
   LI
   LO
   TS
CP0459197
3-(2-(2-ethyl-2-(4-fluorobenzoyl)hydrazinyl)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C22H21FN4O5
 1
1
IC50 = 840 nM
   TI
   LI
   LO
   TS
CP0501543
3-(2-(2-ethyl-2-(4-fluorophenyl)hydrazinyl)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C21H21FN4O4
 1
1
IC50 = 840 nM
   TI
   LI
   LO
   TS
CP0551846
5-[(2,3-difluorophenyl)sulfanylmethyl]-2-phenyl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C18H12F2N4OS
 1
1
IC50 = 850 nM
   TI
   LI
   LO
   TS
CP0524705
5-[(2,3-difluorophenyl)sulfanylmethyl]-2-(3-methylfuran-2-yl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C18H13F2N3O2S
 1
1
IC50 = 870 nM
   TI
   LI
   LO
   TS
CP0418215
2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-4-propan-2-yl-1H-pyrimidine-5-carbonitrile
   Show/Hide
C15H13F2N3OS
 1
1
IC50 = 900 nM
   TI
   LI
   LO
   TS
CP0501346
1-(2-Bromo-phenyl)-3-(4-chloro-2-hydroxy-phenyl)-urea
   Show/Hide
C13H10BrClN2O2
 1
1
IC50 = 906 nM
   TI
   LI
   LO
   TS
CP0551847
5-[(2,3-difluorophenyl)sulfanylmethyl]-2-propan-2-yl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C15H14F2N4OS
 1
1
IC50 = 910 nM
   TI
   LI
   LO
   TS
CP0940266
3-(3,4-dioxo-2-(phenethylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C21H21N3O4
 1
1
IC50 = 926 nM
   TI
   LI
   LO
   TS
CP0503695
7-chloro-1,1-dioxo-3-(2-trifluoromethoxy-phenylamino)-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C14H9ClF3N3O4S
 1
1
IC50 = 930 nM
   TI
   LI
   LO
   TS
CP0565509
1-(5-chloro-2-hydroxy-4-nitrophenyl)-3-phenylurea
   Show/Hide
C13H10ClN3O4
 1
1
IC50 = 950 nM
   TI
   LI
   LO
   TS
CP0940264
3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxybenzoic acid
   Show/Hide
C17H12N2O5
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0543144
5-[2-(2,3-difluorophenyl)ethyl]-2-(hydroxymethyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C15H13F2N3O2
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0470434
3-(2-(2-acetyl-2-ethylhydrazinyl)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C17H20N4O5
 1
1
IC50 = 1250 nM
   TI
   LI
   LO
   TS
CP0401442
2-[(2,3-difluorophenyl)methylsulfanyl]-4-(4-methylphenyl)-6-oxo-1H-pyrimidine-5-carbonitrile
   Show/Hide
C19H13F2N3OS
 1
1
IC50 = 1400 nM
   TI
   LI
   LO
   TS
CP0571403
5-bromo-4-cyclopropyl-2-[(2,3-difluorophenyl)methylsulfanyl]-1H-pyrimidin-6-one
   Show/Hide
C14H11BrF2N2OS
 1
1
IC50 = 1400 nM
   TI
   LI
   LO
   TS
CP0469214
5-[(2,3-difluorophenyl)sulfanylmethyl]-2-methyl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C13H10F2N4OS
 1
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
CP0541618
3-(2-bromo-6-fluoro-phenylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C13H8BrClFN3O3S
 1
1
IC50 = 1600 nM
   TI
   LI
   LO
   TS
CP0508248
2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-4-(4-propan-2-yloxyphenyl)-1H-pyrimidine-5-carbonitrile
   Show/Hide
C21H17F2N3O2S
 1
1
IC50 = 1600 nM
   TI
   LI
   LO
   TS
CP0415464
2-benzyl-5-[(3,4-difluorophenyl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C19H14F2N4OS
 1
1
IC50 = 1700 nM
   TI
   LI
   LO
   TS
CP0473433
2-[(2,3-difluorophenyl)sulfanylmethyl]-7,8,9,10-tetrahydro-6H-pyrimido[1,2-b]indazol-4-one
   Show/Hide
C17H15F2N3OS
 1
1
IC50 = 1700 nM
   TI
   LI
   LO
   TS
CP0543145
2-benzyl-5-[(2,3-dichlorophenyl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C19H14Cl2N4OS
 1
1
IC50 = 1700 nM
   TI
   LI
   LO
   TS
CP0385631
4-cyclobutyl-2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-1H-pyrimidine-5-carbonitrile
   Show/Hide
C16H13F2N3OS
 1
1
IC50 = 1700 nM
   TI
   LI
   LO
   TS
CP0372184
3-(2-hydroxy-6-methylphenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
   Show/Hide
C17H14N2O3
 1
1
IC50 = 1720 nM
   TI
   LI
   LO
   TS
CP0524707
2-methyl-5-(phenylsulfanylmethyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C14H13N3OS
 2
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
2
IC50 = 10300 nM
   TI
   LI
   LO
   TS
CP0433339
7-chloro-1,1-dioxo-3-phenylamino-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C13H10ClN3O3S
 1
1
IC50 = 2400 nM
   TI
   LI
   LO
   TS
CP0539154
3-(2-bromo-phenylamino)-8-fluoro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C13H9BrFN3O3S
 1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0955682
4-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-3-hydroxybenzoic acid
   Show/Hide
C17H12N2O5
 1
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS
CP0550908
4-cyclopropyl-2-[(2,3-difluorophenyl)methylsulfanyl]-5-iodo-1H-pyrimidin-6-one
   Show/Hide
C14H11F2IN2OS
 1
1
IC50 = 3200 nM
   TI
   LI
   LO
   TS
CP0487910
4-tert-butyl-2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-1H-pyrimidine-5-carbonitrile
   Show/Hide
C16H15F2N3OS
 1
1
IC50 = 3700 nM
   TI
   LI
   LO
   TS
CP0494468
2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-4-phenyl-1H-pyrimidine-5-carbonitrile
   Show/Hide
C18H11F2N3OS
 1
1
IC50 = 3700 nM
   TI
   LI
   LO
   TS
CP0538401
3-(2-bromo-5-fluoro-phenylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C13H8BrClFN3O3S
 1
1
IC50 = 3900 nM
   TI
   LI
   LO
   TS
CP0382022
2-benzyl-5-[(2,5-dimethylfuran-3-yl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C19H18N4O2S
 1
1
IC50 = 4100 nM
   TI
   LI
   LO
   TS
CP0462349
2-benzyl-5-[[3-(4-methylphenyl)phenyl]sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C26H22N4OS
 1
1
IC50 = 4100 nM
   TI
   LI
   LO
   TS
CP0551845
5-[(2,3-difluorophenyl)sulfanylmethyl]-7-oxo-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile
   Show/Hide
C14H8F2N4OS
 1
1
IC50 = 4100 nM
   TI
   LI
   LO
   TS
CP0487909
2-[(2,3-difluorophenyl)methylsulfanyl]-4-methyl-6-oxo-1H-pyrimidine-5-carbonitrile
   Show/Hide
C13H9F2N3OS
 1
1
IC50 = 4300 nM
   TI
   LI
   LO
   TS
CP0413574
2-[(2,6-dichlorophenyl)methylsulfanyl]-6-oxo-4-phenyl-1H-pyrimidine-5-carbonitrile
   Show/Hide
C18H11Cl2N3OS
 2
1
IC50 = 4300 nM
   TI
   LI
   LO
   TS
2
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0522294
1-[2-(7-chloro-5-hydroxy-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-3-ylamino)-phenyl]-ethanone
   Show/Hide
C15H12ClN3O4S
 1
1
IC50 = 4500 nM
   TI
   LI
   LO
   TS
CP0489384
2-[(2,3-difluorophenyl)methylsulfanyl]-4-(4-methoxy-3-methylphenyl)-6-oxo-1H-pyrimidine-5-carbonitrile
   Show/Hide
C20H15F2N3O2S
 1
1
IC50 = 4600 nM
   TI
   LI
   LO
   TS
CP0385741
2-[(2,3-difluorophenyl)methylsulfanyl]-4-(3-methylphenyl)-6-oxo-1H-pyrimidine-5-carbonitrile
   Show/Hide
C19H13F2N3OS
 1
1
IC50 = 4700 nM
   TI
   LI
   LO
   TS
CP0539019
2-benzyl-5-[(2,4-dichlorophenyl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C19H14Cl2N4OS
 1
1
IC50 = 4800 nM
   TI
   LI
   LO
   TS
CP0515395
4-cyclopropyl-6-oxo-2-(1-phenylethylsulfanyl)-1H-pyrimidine-5-carbonitrile
   Show/Hide
C16H15N3OS
 1
1
IC50 = 4800 nM
   TI
   LI
   LO
   TS
CP0566173
4-cyclopentyl-2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-1H-pyrimidine-5-carbonitrile
   Show/Hide
C17H15F2N3OS
 1
1
IC50 = 4900 nM
   TI
   LI
   LO
   TS
CP0522295
3-(4-bromo-phenylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C13H9BrClN3O3S
 1
1
IC50 = 5100 nM
   TI
   LI
   LO
   TS
CP0458372
3-(2-chloro-phenylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C13H10ClN3O3S
 1
1
IC50 = 5200 nM
   TI
   LI
   LO
   TS
CP0433340
3-(3-bromo-phenylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C13H9BrClN3O3S
 1
1
IC50 = 6100 nM
   TI
   LI
   LO
   TS
CP0384488
3-(2-(2-ethyl-2-(4-fluorobenzyl)hydrazinyl)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C22H23FN4O4
 1
1
IC50 = 6340 nM
   TI
   LI
   LO
   TS
CP0418322
2-benzyl-5-[[3-(trifluoromethoxy)phenyl]sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C20H15F3N4O2S
 1
1
IC50 = 6400 nM
   TI
   LI
   LO
   TS
CP0379277
4-cyclopropyl-6-oxo-2-(2-phenylpropan-2-ylsulfanyl)-1H-pyrimidine-5-carbonitrile
   Show/Hide
C17H17N3OS
 1
1
IC50 = 6400 nM
   TI
   LI
   LO
   TS
CP0940265
2-hydroxy-N,N-dimethyl-3-(2-(methyl(phenyl)amino)-3,4-dioxocyclobut-1-enylamino)benzamide
   Show/Hide
C20H19N3O4
 1
1
IC50 = 7200 nM
   TI
   LI
   LO
   TS
CP0385632
4-(4-chlorophenyl)-2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-1H-pyrimidine-5-carbonitrile
   Show/Hide
C18H10ClF2N3OS
 1
1
IC50 = 7400 nM
   TI
   LI
   LO
   TS
CP0538326
2-benzyl-5-[(4-chloro-2,5-dimethylphenyl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C21H19ClN4OS
 1
1
IC50 = 7800 nM
   TI
   LI
   LO
   TS
CP0433341
3-benzylamino-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C14H12ClN3O3S
 1
1
IC50 = 8000 nM
   TI
   LI
   LO
   TS
CP0845752
3-(4-nitrophenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
   Show/Hide
C16H11N3O4
 1
1
IC50 = 8600 nM
   TI
   LI
   LO
   TS
CP0550907
4-cyclopropyl-2-[(2,3-difluorophenyl)sulfanylmethyl]-6-oxo-1H-pyrimidine-5-carbonitrile
   Show/Hide
C15H11F2N3OS
 1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0418349
[5-[2-(2,3-difluorophenyl)ethyl]-7-methoxypyrazolo[1,5-a]pyrimidin-2-yl]methanol
   Show/Hide
C16H15F2N3O2
 1
1
IC50 = 10500 nM
   TI
   LI
   LO
   TS
CP0434086
2-benzyl-5-[(4-phenyl-1,3-thiazol-2-yl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C22H17N5OS2
 1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS
CP0524706
2-benzyl-5-[(2,4-dimethoxyphenyl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C21H20N4O3S
 1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS
CP0521704
2-[(2-benzyl-7-oxo-1H-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl)methylsulfanyl]pyridine-3-carbonitrile
   Show/Hide
C19H14N6OS
 1
1
IC50 = 13000 nM
   TI
   LI
   LO
   TS
CP0382020
N-[2-benzyl-5-[(2,3-difluorophenyl)sulfanylmethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]methanesulfonamide
   Show/Hide
C20H17F2N5O2S2
 1
1
IC50 = 13900 nM
   TI
   LI
   LO
   TS
CP0522296
3-((R)-sec-butylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C11H14ClN3O3S
 1
1
IC50 = 15000 nM
   TI
   LI
   LO
   TS
CP0405681
7-chloro-3-cyclopentylamino-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C12H14ClN3O3S
 1
1
IC50 = 20000 nM
   TI
   LI
   LO
   TS
CP0551844
5-[(2,3-difluorophenyl)sulfanylmethyl]-3-ethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C15H13F2N3OS
 1
1
IC50 = 20000 nM
   TI
   LI
   LO
   TS
CP0565510
1-(2-hydroxy-4-methylphenyl)-3-phenylurea
   Show/Hide
C14H14N2O2
 1
1
IC50 = 25000 nM
   TI
   LI
   LO
   TS
CP0562098
3-((2-hydroxyphenyl)(methyl)amino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
   Show/Hide
C17H14N2O3
 1
1
IC50 = 28600 nM
   TI
   LI
   LO
   TS
CP0427950
1-(2-hydroxy-6-nitrophenyl)-3-phenylurea
   Show/Hide
C13H11N3O4
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0444712
1-(2-Hydroxy-phenyl)-3-phenyl-urea
   Show/Hide
C13H12N2O2
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0515184
1-(5-chloro-2-hydroxyphenyl)-3-phenylurea
   Show/Hide
C13H11ClN2O2
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0524262
1-(2-hydroxy-6-methylphenyl)-3-phenylurea
   Show/Hide
C14H14N2O2
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0526489
1-(2-hydroxy-5-methylphenyl)-3-phenylurea
   Show/Hide
C14H14N2O2
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0503694
2-(7-chloro-5-hydroxy-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-3-ylamino)-benzoic acid
   Show/Hide
C14H10ClN3O5S
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0503696
7-chloro-3-(2-chloro-benzylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C14H11Cl2N3O3S
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0533073
7-chloro-3-(2-morpholin-4-yl-phenylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
   Show/Hide
C17H17ClN4O4S
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0457363
2-benzyl-5-[(1-propylimidazol-2-yl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C19H20N6OS
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0462350
2-benzyl-5-(pentylsulfanylmethyl)-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
C18H22N4OS
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0463579
2-[(2,3-difluorophenyl)methylsulfanyl]-4-[(1-hydroxy-2-methylpropan-2-yl)amino]-6-phenylpyrimidine-5-carbonitrile
   Show/Hide
C22H20F2N4OS
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0480518
4-cyclopropyl-6-oxo-2-(phenylsulfanylmethyl)-1H-pyrimidine-5-carbonitrile
   Show/Hide
C15H13N3OS
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0574678
N-[5-cyano-2-[(2,3-difluorophenyl)methylsulfanyl]-6-phenylpyrimidin-4-yl]methanesulfonamide
   Show/Hide
C19H14F2N4O2S2
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0372181
1-(2-bromophenyl)-3-(2-hydroxyphenyl)urea
   Show/Hide
C13H11BrN2O2
 1
1
IC50 > 9000 nM
   TI
   LI
   LO
   TS
CP0862453
N-(4-chloro-2-hydroxy-3-{[(3-exo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]sulfonyl}phenyl)-N'-(3-fluoro-2-methylphenyl)urea
   Show/Hide
C22H25ClFN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0862454
N-{4-chloro-2-hydroxy-3-[(3S)-3-pyrrolidinylsulfonyl]-phenyl}-N'-(3-fluoro-2-methylphenyl)urea
   Show/Hide
C18H19ClFN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0862455
N-{4-chloro-2-hydroxy-3-[3-pyrrolidinylmethyl)sulfonyl]-phenyl}-N'-{2-[(trifluoromethyl)oxy]phenyl}-urea
   Show/Hide
C19H19ClF3N3O5S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0862458
N-{3-[(1R,5S)-8-azabicyclo[3.2.1]oct-3-yisulfonyl]-4-chloro-2-hydroxyphenyl}-N'-(3-fluoro-2-methylphenyl)urea
   Show/Hide
C21H23ClFN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0862459
N-(2-chloro-3-fluorophenyl)-N'-{4-chloro-2-hydroxy-3-[(3S)-3-piperidinylsulfonyl]phenyl}urea
   Show/Hide
C18H18Cl2FN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0862460
N-[4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl-)phenyl]-N'-(2-chloro-3-pyridinyl)urea
   Show/Hide
C17H18Cl2N4O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0862481
N-(2-chloro-3-fluorophenyl)-N'-{4-chloro-2-hydroxy-3-[(3R)-pyrrolidinylsulfonyl]-phenyl}urea
   Show/Hide
C17H16Cl2FN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0903454
N-[4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl)-phenyl]-N'-(3-fluoro-2-methylphenyl)urea
   Show/Hide
C19H21ClFN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0903457
N-[4-chloro-2-hydroxy-3-(4-piperidinylsulfonyl)-phenyl]-N'-(2,2-difluoro-1,3-benzodioxol-4-yl)urea
   Show/Hide
C19H18ClF2N3O6S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0903458
N-{4-chloro-2-hydroxy-3-[(3S)-3-pyrrolidinylsulfonyl]-phenyl}-N'-(2-chloro-3-pyridinyl)urea
   Show/Hide
C16H16Cl2N4O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0903459
Ethyl 4-({6-chloro-2-hydroxy-3-[({[2-(phenylox-y)phenyl]amino}carbonyl)amino]phenyl}sulfonyl)-1-piperidinecarboxylate
   Show/Hide
C27H28ClN3O7S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0903460
N-{4-chloro-2-hydroxy-3-[(3R)-3-pyrrolidinylsulfonyl]-phenyl}-N'-(2-ethylphenyl)urea
   Show/Hide
C19H22ClN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0903461
N-(2-chloro-3-fluorophenyl)-N'-[4-chloro-2-hydroxy-3-(4-piperidinylsulfonyl)-phenyl)urea
   Show/Hide
C18H18Cl2FN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0903462
N-{3-[(1R,5S)-8-azabicyclo[3.2.1]oct-3-ylsulfonyl]-4-chloro-2-hydroxyphenyl}-N'-(2-chloro-3-pyridinyl)urea
   Show/Hide
C19H20Cl2N4O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0903463
N-[4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl)-phenyl]-N'-{2-[(trifluoromethyl)oxy]-phenyljurea
   Show/Hide
C19H19ClF3N3O5S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0920833
N-[4-chloro-2-hydroxy-3-(4-piperidinylsulfonyl)-phenyl]-N'-(2-ethylphenyl)urea
   Show/Hide
C20H24ClN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0920834
ethyl4-{[6-chloro-3-({[(3-fluoro-2-methylphenyl)amino]-carbonyljamino]-2-hydroxyphenyl[sulfonyl}-1-piperidinecarboxylate
   Show/Hide
C22H25ClFN3O6S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0920835
N-{3-[(1R,5S)-8-azabicyclo[3.2.1]oct-3-yl]sulfonyl]-4-chloro-2-hydroxyphenyl}-N'-[2-(phenyloxy)phenyl)urea
   Show/Hide
C26H26ClN3O5S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0920836
N-{4-chloro-2-hydroxy-3-[(3R)-3-pyrrolidinylsulfonyl]-phenyl}-N'-(2,2-difluoro-1,3-benzodioxol-4-yl)urea
   Show/Hide
C18H16ClF2N3O6S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0920837
N-[4-chloro-2-hydroxy-3-(4-piperidinylsulfonyl)-phenyl]-N'-(3-fluoro-2-methylphenyl)urea
   Show/Hide
C19H21ClFN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0920838
N-[4-chloro-2-hydroxy-3-(4-piperidinylsulfonyl)-phenyl]-N'-(2-chloro-3-pyridinyl)urea
   Show/Hide
C17H18Cl2N4O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0920839
N-{3-[(lR,5S)-8-azabicyclo[3.2.1]oct-3-yl]sulfonyl]-4-chloro-2-hydroxyphenyl}-N'-(2-chloro-3-fluorophenyl)urea
   Show/Hide
C20H20Cl2FN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0921071
N-[4-chloro-2-hydroxy-3-(4-piperidinylsulfonyl)-phenyl]-N'-{2-[(tritluoromethyl)oxyj-phenyl)urea
   Show/Hide
C19H19ClF3N3O5S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0921715
N-{4-chloro-2-hydroxy-3-[(3S)-3-piperidinylsulfonyl]phenyl}-N'-(2-chloro-3-pyridinyl)urea
   Show/Hide
C17H18Cl2N4O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0921716
N-[4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl)-phenyl]-N'-(2,3-dichlorophenyl)urea
   Show/Hide
C18H18Cl3N3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0921717
N-{4-chloro-2-hydroxy-3-[(3S)-3-pyrrolidinylsulfonyl]-phenyl}-N'-[2-(phenyloxy)phenyl]urea
   Show/Hide
C23H22ClN3O5S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0921718
N-[4-chloro-2-hydroxy-3-(4-piperidinylsulfo-nyl)phenyl]-N'-[2-(phenyloxy)phenyl]urea
   Show/Hide
C24H24ClN3O5S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0921719
DANIRIXIN
   Show/Hide
C19H21ClFN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0921720
N-[3-(3-azetidinylsulfonyl)-4-chloro-2-hydroxyphenyl]-N'-(2-chloro-3-pyridinyl)urea
   Show/Hide
C15H14Cl2N4O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0921721
N-[4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl)-phenyl]-N'-(2-ethylphenyl)urea
   Show/Hide
C20H24ClN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0922634
N-{4-chloro-2-hydroxy-3-[(3R)-3-pyrrolidinylsulfonyl]-phenyl}-N'-(2-(trifluoromethyl)oxy]-phenyl)urea
   Show/Hide
C18H17ClF3N3O5S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0923161
N-{4-chloro-2-hydroxy-3-[(3-pyrrolidinylmethyl)-sulfonyl]phenyl}-N'-(3-fluoro-2-methylphenyl)urea
   Show/Hide
C19H21ClFN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0928820
N-(2-chloro-3-fluorophenyl)-N'-{4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl)-phenyl)urea
   Show/Hide
C18H18Cl2FN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0930310
N-(2-chloro-3-fluorophenyl)-N'-{4-chloro-2-hydroxy-3-[(3-pyrrolidinylmethyl)-sulfonyl]phenyl}urea
   Show/Hide
C18H18Cl2FN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0943508
ethyl4-{[6-chloro-3-({[(2-chloro-3-fluorophenyl)amino]-carbonyljamino]-2-hydroxyphenyl[sulfonyl}-1-piperidinecarboxylate
   Show/Hide
C21H22Cl2FN3O6S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0947357
N-[3-(3-azetidinylsulfonyl)-4-chloro-2-hydroxyphenyl]-N'-(3-fluoro-3-methylphenyl)urea
   Show/Hide
C17H17ClFN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0947358
N-(2-chloro-3-fluorophenyl)-N'-{4-chloro-2-hydroxy-3-[(3S)-3-pyrrolidinylsulfonyl]-phenyl)urea
   Show/Hide
C17H16Cl2FN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0952635
N-[3-(3-azetidinylsulfonyl)-4-chloro-2-hydroxyphenyl]-N'-(2-chloro-3-fluorophenyl)urea
   Show/Hide
C16H14Cl2FN3O4S
 1
1
IC50 < 30000 nM
   TI
   LI
   LO
   TS
CP0471149
3-(2-((R)-1-(4-sec-butylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C24H29N3O5
 1
1
Ki = 0.6 nM
   TI
   LI
   LO
   TS
CP0444765
(R)-3-(3,4-dioxo-2-(1-(4-(pentan-3-yl)furan-2-yl)propylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C25H31N3O5
 1
1
Ki = 0.8 nM
   TI
   LI
   LO
   TS
CP0502070
(R)-3-(2-(1-(4-ethylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C22H25N3O5
 1
1
Ki = 1 nM
   TI
   LI
   LO
   TS
CP0467181
(R)-2-hydroxy-3-(2-(1-(4-isopropylfuran-2-yl)ethylamino)-3,4-dioxocyclobut-1-enylamino)-N,N-dimethylbenzamide
   Show/Hide
C22H25N3O5
 1
1
Ki = 2 nM
   TI
   LI
   LO
   TS
CP0528071
(R)-3-(2-(1-(4-butylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C24H29N3O5
 1
1
Ki = 2 nM
   TI
   LI
   LO
   TS
CP0461709
(R)-3-(2-(1-(4-cyclopentylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C25H29N3O5
 1
1
Ki = 3 nM
   TI
   LI
   LO
   TS
CP0467184
(R)-3-(2-(cyclopropyl(4-isopropylfuran-2-yl)methylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C24H27N3O5
 1
1
Ki = 3 nM
   TI
   LI
   LO
   TS
CP0457569
(R)-3-(2-(1-(4-cyclohexylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C26H31N3O5
 1
1
Ki = 4 nM
   TI
   LI
   LO
   TS
CP0461707
(R)-2-hydroxy-3-(2-(1-(4-isopropylfuran-2-yl)-2-methylpropylamino)-3,4-dioxocyclobut-1-enylamino)-N,N-dimethylbenzamide
   Show/Hide
C24H29N3O5
 1
1
Ki = 4 nM
   TI
   LI
   LO
   TS
CP0467179
(R)-2-hydroxy-3-(2-(1-(4-isopropylfuran-2-yl)-2,2-dimethylpropylamino)-3,4-dioxocyclobut-1-enylamino)-N,N-dimethylbenzamide
   Show/Hide
C25H31N3O5
 1
1
Ki = 4 nM
   TI
   LI
   LO
   TS
CP0467183
(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(4-methylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide
   Show/Hide
C21H23N3O5
 1
1
Ki = 4 nM
   TI
   LI
   LO
   TS
CP0485168
(R)-3-(2-(1-(4-tert-butylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C24H29N3O5
 1
1
Ki = 4 nM
   TI
   LI
   LO
   TS
CP0052095
(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide
   Show/Hide
C21H23N3O5
 1
1
Ki = 5 nM
   TI
   LI
   LO
   TS
CP0467185
(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(4-methylthiophen-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide
   Show/Hide
C21H23N3O4S
 1
1
Ki = 5 nM
   TI
   LI
   LO
   TS
CP0500390
(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylthiophen-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide
   Show/Hide
C21H23N3O4S
 1
1
Ki = 5 nM
   TI
   LI
   LO
   TS
CP0453928
(S)-3-(3,4-dioxo-2-(2,2,2-trifluoro-1-(4-isopropylfuran-2-yl)ethylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C22H22F3N3O5
 1
1
Ki = 6 nM
   TI
   LI
   LO
   TS
CP0461711
(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(4-(4-morpholinobutyl)furan-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide
   Show/Hide
C28H36N4O6
 1
1
Ki = 9 nM
   TI
   LI
   LO
   TS
CP0542184
(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(3-methylthiophen-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide
   Show/Hide
C21H23N3O4S
 1
1
Ki = 10 nM
   TI
   LI
   LO
   TS
CP0407923
(2S)-2-(6-butyl-2-(4-(4-(trifluoromethyl)phenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C29H39F3N6O2
 1
1
Ki = 14 nM
   TI
   LI
   LO
   TS
CP0432128
(2S)-2-(6-butyl-2-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C29H39F3N6O3
 1
1
Ki = 17 nM
   TI
   LI
   LO
   TS
CP0458492
(R)-3-(2-(1-(3-ethylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
   Show/Hide
C22H25N3O5
 1
1
Ki = 25 nM
   TI
   LI
   LO
   TS
CP0485592
(2S)-N-(3-ethoxypropyl)-4-methyl-2-(6-propyl-2-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)pentanamide
   Show/Hide
C28H37F3N6O3
 1
1
Ki = 25 nM
   TI
   LI
   LO
   TS
CP0522677
(2S)-2-(6-butyl-2-(4-(4-chlorophenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C28H39ClN6O2
 1
1
Ki = 27 nM
   TI
   LI
   LO
   TS
CP0435302
(2S)-2-(6-butyl-2-(4-(4-hydroxyphenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C28H40N6O3
 1
1
Ki = 32 nM
   TI
   LI
   LO
   TS
CP0394245
(2S)-N-(3-ethoxypropyl)-4-methyl-2-(6-propyl-2-(4-(3-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)pentanamide
   Show/Hide
C28H37F3N6O3
 1
1
Ki = 35 nM
   TI
   LI
   LO
   TS
CP0445644
(2S)-2-(6-butyl-2-(4-(4-fluorophenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C28H39FN6O2
 1
1
Ki = 37 nM
   TI
   LI
   LO
   TS
CP0559378
(2S)-2-(6-butyl-2-(4-p-tolyl-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C29H42N6O2
 1
1
Ki = 40 nM
   TI
   LI
   LO
   TS
CP0432130
(2S)-2-(6-butyl-2-(4-(4-methoxyphenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C29H42N6O3
 1
1
Ki = 42 nM
   TI
   LI
   LO
   TS
CP0424977
(2S)-2-(6-butyl-2-(4-(4-cyanophenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C29H39N7O2
 1
1
Ki = 43 nM
   TI
   LI
   LO
   TS
CP0525972
(2S)-N-(3-ethoxypropyl)-4-methyl-2-(6-methyl-2-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)pentanamide
   Show/Hide
C26H33F3N6O3
 1
1
Ki = 44 nM
   TI
   LI
   LO
   TS
CP0435538
(2S)-N-(3-ethoxypropyl)-4-methyl-2-(6-propyl-2-(4-(2-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)pentanamide
   Show/Hide
C28H37F3N6O3
 1
1
Ki = 50 nM
   TI
   LI
   LO
   TS
CP0436976
(2S)-N-(3-ethoxypropyl)-2-(6-ethyl-2-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)-4-methylpentanamide
   Show/Hide
C27H35F3N6O3
 1
1
Ki = 57 nM
   TI
   LI
   LO
   TS
CP0407922
(2S)-2-(2-(1H-imidazol-1-yl)-6-(octylthio)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C26H44N6O2S
 1
1
Ki = 60 nM
   TI
   LI
   LO
   TS
CP0424820
(2S)-2-(6-butyl-2-(4-tert-butyl-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C26H44N6O2
 1
1
Ki = 85 nM
   TI
   LI
   LO
   TS
CP0432835
(2S)-2-(6-butyl-2-(4-methyl-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C23H38N6O2
 1
1
Ki = 90 nM
   TI
   LI
   LO
   TS
CP0552169
(2S)-2-(6-butyl-2-(4-phenyl-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C28H40N6O2
 1
1
Ki = 100 nM
   TI
   LI
   LO
   TS
CP0436979
(2S)-2-(2-(1H-imidazol-1-yl)-6-octylpyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C26H44N6O2
 1
1
Ki = 120 nM
   TI
   LI
   LO
   TS
CP0435539
(2S)-2-(6-butyl-2-(4-(4-nitrophenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C28H39N7O4
 1
1
Ki = 160 nM
   TI
   LI
   LO
   TS
CP0432127
(2S)-N-(3-ethoxypropyl)-4-methyl-2-(2-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)pentanamide
   Show/Hide
C25H31F3N6O3
 1
1
Ki = 200 nM
   TI
   LI
   LO
   TS
CP0432132
(2S)-N-(3-ethoxypropyl)-2-(6-hexyl-2-(1H-imidazol-1-yl)pyrimidin-4-ylamino)-4-methylpentanamide
   Show/Hide
C24H40N6O2
 1
1
Ki = 290 nM
   TI
   LI
   LO
   TS
CP0516395
(2S)-2-(2-(4-(4-aminophenyl)-1H-imidazol-1-yl)-6-butylpyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C28H41N7O2
 1
1
Ki = 600 nM
   TI
   LI
   LO
   TS
CP0559379
(2S)-2-(6-butyl-2-(pyridin-3-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C24H37N5O2
 1
1
Ki = 750 nM
   TI
   LI
   LO
   TS
CP0407924
(2S)-2-(6-butyl-2-(1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C22H36N6O2
 1
1
Ki = 1700 nM
   TI
   LI
   LO
   TS
CP0485846
(2S)-2-(6-tert-butyl-2-(1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C22H36N6O2
 1
1
Ki = 6000 nM
   TI
   LI
   LO
   TS
CP0442167
(2S)-2-(6-butyl-2-(1H-1,2,4-triazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C21H35N7O2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0562163
(2S)-2-(6-butyl-2-(2-methyl-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C23H38N6O2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0435541
(S)-2-(6-butyl-2-(pyridin-4-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
   Show/Hide
C24H37N5O2
 1
1
Ki > 5000 nM
   TI
   LI
   LO
   TS