Compound ID |
Compound Name |
Compound Formula |
CP0444705
|
(R)-2-hydroxy-3-(2-(1-(4-isopropylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-N,N-dimethylbenzamide
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|
C23H27N3O5
|
2
|
1 |
IC50 = 1.3 nM
|
|
|
2 |
Ki = 1 nM
|
|
|
CP0845753
|
3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C19H17N3O4
|
2
|
1 |
IC50 = 2 nM
|
|
|
2 |
IC50 = 26 nM
|
|
|
CP0861701
|
5-chloro-3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C19H16ClN3O4
|
1
|
1 |
IC50 = 2 nM
|
|
|
CP0924832
|
4-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-3-hydroxybenzonitrile
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|
C17H11N3O3
|
2
|
1 |
IC50 = 3 nM
|
|
|
2 |
IC50 = 15 nM
|
|
|
CP0464255
|
3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino}-6-fluoro-2-hydroxy-N,N-dimethylbenzenesulfonamide
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|
C16H15BrFN5O3S
|
1
|
1 |
IC50 = 4 nM
|
|
|
CP0427078
|
3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino}-6-chloro-2-hydroxy-N,N-dimethylbenzenesulfonamide
Show/Hide
|
C16H15BrClN5O3S
|
1
|
1 |
IC50 = 5 nM
|
|
|
CP0917519
|
3-(3,4-dioxo-2-(pentan-3-ylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
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|
C18H23N3O4
|
2
|
1 |
IC50 = 5 nM
|
|
|
2 |
IC50 = 19.1 nM
|
|
|
CP0378831
|
3-(2-bromophenyl)-2-cyano-1-(2-hydroxy-4-methyl-3-{[3-(morpholin-4-yl)pentan-3-yl]sulfamoyl}phenyl)guanidine
Show/Hide
|
C24H31BrN6O4S
|
1
|
1 |
IC50 = 6 nM
|
|
|
CP0498665
|
2-[(2,3-difluorophenyl)methylsulfanyl]-4-[(1S,2S)-2-(hydroxymethyl)cyclopropyl]-6-oxo-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C16H13F2N3O2S
|
1
|
1 |
IC50 = 6 nM
|
|
|
CP0394699
|
3-[3-(2-Bromo-phenyl)-ureido]-6-chloro-2-hydroxy-benzenesulfonamide
Show/Hide
|
C13H11BrClN3O4S
|
1
|
1 |
IC50 = 7 nM
|
|
|
CP0378832
|
3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino}-2-hydroxy-N,N,6-trimethylbenzenesulfonamide
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|
C17H18BrN5O3S
|
1
|
1 |
IC50 = 7 nM
|
|
|
CP0383548
|
3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino}-2-hydroxy-N,N-dimethyl-6-(trifluoromethyl)benzenesulfonamide
Show/Hide
|
C17H15BrF3N5O3S
|
1
|
1 |
IC50 = 7 nM
|
|
|
CP0550905
|
(1S,2S)-2-[5-cyano-2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-1H-pyrimidin-4-yl]cyclopropane-1-carboxamide
Show/Hide
|
C16H12F2N4O2S
|
1
|
1 |
IC50 = 7 nM
|
|
|
CP0565512
|
6-chloro-3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxy-N-(2-methoxyethyl)benzenesulfonamide
Show/Hide
|
C19H18ClN3O6S
|
1
|
1 |
IC50 = 8 nM
|
|
|
CP0915922
|
3-[4-chloro-3-(4-ethyl-piperazine-1-sulfonyl)-2-hydroxy-phenylamino]-4-(2-propyl-phenylamino)-cyclobut-3-ene-1,2-dione trifluoro-acetic acid salt
Show/Hide
|
C27H30ClF3N4O7S
|
1
|
1 |
IC50 = 8 nM
|
|
|
CP0910930
|
3-(2-(cyclopentylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
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|
C18H21N3O4
|
2
|
1 |
IC50 = 8 nM
|
|
|
2 |
IC50 = 144.8 nM
|
|
|
CP0383549
|
3-(2-bromophenyl)-1-[4-chloro-3-({3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pentan-3-yl}sulfamoyl)-2-hydroxyphenyl]-2-cyanoguanidine
Show/Hide
|
C25H32BrClN6O4S
|
1
|
1 |
IC50 = 9 nM
|
|
|
CP0464257
|
3-[2-(benzyloxy)phenyl]-1-[4-chloro-3-(dimethylsulfamoyl)-2-hydroxyphenyl]-2-cyanoguanidine
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|
C23H22ClN5O4S
|
1
|
1 |
IC50 = 9 nM
|
|
|
CP0486903
|
6-chloro-3-({(cyanoimino)[(2-fluorophenyl)amino]methyl}amino)-2-hydroxy-N,N-dimethylbenzenesulfonamide
Show/Hide
|
C16H15ClFN5O3S
|
1
|
1 |
IC50 = 9 nM
|
|
|
CP0496884
|
3-[3-(2-Bromo-phenyl)-ureido]-6-chloro-2-hydroxy-benzamide
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|
C14H11BrClN3O3
|
1
|
1 |
IC50 = 10 nM
|
|
|
CP0844753
|
3-(2-bromophenylamino)-4-(4-chloro-2-hydroxy-3-(4-methyl-1,4-diazepan-1-ylsulfonyl)phenylamino)cyclobut-3-ene-1,2-dione hydrochloride
Show/Hide
|
C22H23BrCl2N4O5S
|
1
|
1 |
IC50 = 10 nM
|
|
|
CP0955021
|
3-(2-(cyclohexylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C19H23N3O4
|
1
|
1 |
IC50 = 10 nM
|
|
|
CP0955683
|
2-hydroxy-3-(2-(isopropylamino)-3,4-dioxocyclobut-1-enylamino)-N,N-dimethylbenzamide
Show/Hide
|
C16H19N3O4
|
1
|
1 |
IC50 = 10 nM
|
|
|
CP0410626
|
(1S,2S)-2-[5-cyano-2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-1H-pyrimidin-4-yl]cyclopropane-1-carboxylic acid
Show/Hide
|
C16H11F2N3O3S
|
1
|
1 |
IC50 = 10 nM
|
|
|
CP0439048
|
3-[3-(2-Bromo-phenyl)-ureido]-6-chloro-2-hydroxy-N,N-dimethyl-benzenesulfonamide
Show/Hide
|
C15H15BrClN3O4S
|
1
|
1 |
IC50 = 12 nM
|
|
|
CP0383550
|
3-(2-bromophenyl)-2-cyano-1-(2-hydroxy-3-{[3-(morpholin-4-yl)pentan-3-yl]sulfamoyl}phenyl)guanidine
Show/Hide
|
C23H29BrN6O4S
|
1
|
1 |
IC50 = 12 nM
|
|
|
CP0486902
|
6-chloro-3-[((cyanoimino){[2-(trifluoromethyl)phenyl]amino}methyl)amino]-2-hydroxy-N,N-dimethylbenzenesulfonamide
Show/Hide
|
C17H15ClF3N5O3S
|
1
|
1 |
IC50 = 12 nM
|
|
|
CP0918672
|
3-(2-bromo-phenylamino)-4-[4-fluoro-2-hydroxy-3-(4-methyl-piperazine-1-sulfonyl)-phenylamino]-cyclobut-3-ene-1,2-dione trifluoro-acetic acid salt
Show/Hide
|
C23H21BrF4N4O7S
|
1
|
1 |
IC50 = 13 nM
|
|
|
CP0464254
|
1-[4-chloro-3-(dimethylsulfamoyl)-2-hydroxyphenyl]-2-cyano-3-(2-phenylphenyl)guanidine
Show/Hide
|
C22H20ClN5O3S
|
1
|
1 |
IC50 = 13 nM
|
|
|
CP0526490
|
6-chloro-3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxybenzamide
Show/Hide
|
C17H12ClN3O4
|
1
|
1 |
IC50 = 14 nM
|
|
|
CP0955684
|
3-(2-(tert-butylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C17H21N3O4
|
1
|
1 |
IC50 = 14 nM
|
|
|
CP0501838
|
3-(2-(o-toluidino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N,6-trimethylbenzenesulfonamide
Show/Hide
|
C20H21N3O5S
|
1
|
1 |
IC50 = 15 nM
|
|
|
CP0464256
|
6-chloro-3-({(cyanoimino)[(2-ethylphenyl)amino]methyl}amino)-2-hydroxy-N,N-dimethylbenzenesulfonamide
Show/Hide
|
C18H20ClN5O3S
|
1
|
1 |
IC50 = 15 nM
|
|
|
CP0524530
|
(R)-1-(3-(3-(3-(2-bromophenyl)-2-cyanoguanidino)-6-chloro-2-hydroxyphenylsulfonamido)pentan-3-yl)pyrrolidine-2-carboxylic acid
Show/Hide
|
C24H28BrClN6O5S
|
1
|
1 |
IC50 = 16 nM
|
|
|
CP0399972
|
1-[4-chloro-3-({3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pentan-3-yl}sulfamoyl)-2-hydroxyphenyl]-2-cyano-3-(2-methylphenyl)guanidine
Show/Hide
|
C26H35ClN6O4S
|
1
|
1 |
IC50 = 17 nM
|
|
|
CP0427088
|
6-chloro-3-({(cyanoimino)[(2-methylphenyl)amino]methyl}amino)-2-hydroxy-N,N-dimethylbenzenesulfonamide
Show/Hide
|
C17H18ClN5O3S
|
1
|
1 |
IC50 = 17 nM
|
|
|
CP0873266
|
3-(4-chloro-2-hydroxy-3-(4-(piperidin-1-yl)piperidin-1-ylsulfonyl)phenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione hydrochloride
Show/Hide
|
C26H30Cl2N4O5S
|
1
|
1 |
IC50 = 18 nM
|
|
|
CP0920871
|
3-(4-chloro-2-hydroxy-3-(4-methyl-1,4-diazepan-1-ylsulfonyl)phenylamino)-4-(2-chlorophenylamino)cyclobut-3-ene-1,2-dione hydrochloride
Show/Hide
|
C22H23Cl3N4O5S
|
1
|
1 |
IC50 = 20 nM
|
|
|
CP0068783
|
1-(2-bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea
Show/Hide
|
C13H10BrN3O4
|
1
|
1 |
IC50 = 22 nM
|
|
|
CP0853168
|
3-(2-hydroxy-4-nitrophenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
Show/Hide
|
C16H11N3O5
|
2
|
1 |
IC50 = 22 nM
|
|
|
2 |
IC50 = 36 nM
|
|
|
CP0432840
|
1-(3-{[3-(4-aminopiperidin-1-yl)pentan-3-yl]sulfamoyl}-4-chloro-2-hydroxyphenyl)-3-(2-bromophenyl)-2-cyanoguanidine
Show/Hide
|
C24H31BrClN7O3S
|
1
|
1 |
IC50 = 22 nM
|
|
|
CP0846916
|
3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxy-N-methylbenzamide
Show/Hide
|
C18H15N3O4
|
1
|
1 |
IC50 = 22 nM
|
|
|
CP0565508
|
1-(2-Bromo-phenyl)-3-(4-cyano-2-hydroxy-phenyl)-urea
Show/Hide
|
C14H10BrN3O2
|
1
|
1 |
IC50 = 25 nM
|
|
|
CP0373706
|
3-(2-bromo-phenylamino)-7-nitro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C13H9BrN4O5S
|
1
|
1 |
IC50 = 26 nM
|
|
|
CP0939748
|
3-[2-hydroxy-3-(4-methyl-piperazine-1-carbonyl)-phenylamino]-4-phenylamino-cyclobut-3-ene-1,2-dione trifluoro-acetic acid salt
Show/Hide
|
C24H23F3N4O6
|
1
|
1 |
IC50 = 27 nM
|
|
|
CP0471390
|
3-(2-bromophenylamino)-4-(4-chloro-2-hydroxy-3-(pyrrolidine-1-carbonyl)phenylamino)cyclobut-3-ene-1,2-dione
Show/Hide
|
C21H17BrClN3O4
|
1
|
1 |
IC50 = 28 nM
|
|
|
CP0383551
|
6-chloro-3-{[[(3-chloro-2-fluorophenyl)amino](cyanoimino)methyl]amino}-2-hydroxy-N,N-dimethylbenzenesulfonamide
Show/Hide
|
C16H14Cl2FN5O3S
|
1
|
1 |
IC50 = 29 nM
|
|
|
CP0464799
|
3-(2-bromophenylamino)-4-(4-chloro-2-hydroxyphenylamino)cyclobut-3-ene-1,2-dione
Show/Hide
|
C16H10BrClN2O3
|
1
|
1 |
IC50 = 32 nM
|
|
|
CP0495784
|
3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxybenzonitrile
Show/Hide
|
C17H11N3O3
|
1
|
1 |
IC50 = 32 nM
|
|
|
CP0869605
|
3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxybenzamide
Show/Hide
|
C17H13N3O4
|
1
|
1 |
IC50 = 34 nM
|
|
|
CP0372182
|
3-(2-bromophenylamino)-4-(2-hydroxy-4-nitrophenylamino)cyclobut-3-ene-1,2-dione
Show/Hide
|
C16H10BrN3O5
|
1
|
1 |
IC50 = 37 nM
|
|
|
CP0367896
|
4-cyclopropyl-2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C15H11F2N3OS
|
2
|
1 |
IC50 = 40 nM
|
|
|
2 |
IC50 = 140 nM
|
|
|
CP0955022
|
3-(2-(furan-2-ylmethylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C18H17N3O5
|
1
|
1 |
IC50 = 41 nM
|
|
|
CP0939747
|
3-[2-hydroxy-3-(4-methyl-[1,4]diazepane-1-carbonyl)-phenylamino]-4-phenylamino-cyclobut-3-ene-1,2-dione trifluoro-acetic acid salt
Show/Hide
|
C25H25F3N4O6
|
1
|
1 |
IC50 = 44 nM
|
|
|
CP0096177
|
3-(2-(2,2-diethylhydrazinyl)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C17H22N4O4
|
1
|
1 |
IC50 = 46 nM
|
|
|
CP0490412
|
3-(2-bromophenylamino)-4-(2-hydroxyphenylamino)cyclobut-3-ene-1,2-dione
Show/Hide
|
C16H11BrN2O3
|
1
|
1 |
IC50 = 51 nM
|
|
|
CP0371764
|
3-(5-chloro-2-hydroxy-4-nitrophenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
Show/Hide
|
C16H10ClN3O5
|
1
|
1 |
IC50 = 52 nM
|
|
|
CP0960672
|
methyl 3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxybenzoate
Show/Hide
|
C18H14N2O5
|
1
|
1 |
IC50 = 53 nM
|
|
|
CP0490402
|
3-(5-chloro-2-hydroxyphenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
Show/Hide
|
C16H11ClN2O3
|
1
|
1 |
IC50 = 54 nM
|
|
|
CP0104331
|
7-nitro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C19H14N4O6S
|
1
|
1 |
IC50 = 54 nM
|
|
|
CP0373708
|
7-chloro-1,1-dioxo-3-(2-phenoxy-phenylamino)-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C19H14ClN3O4S
|
1
|
1 |
IC50 = 54 nM
|
|
|
CP0492268
|
3-(2-(2-ethyl-2-phenylhydrazinyl)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C21H22N4O4
|
1
|
1 |
IC50 = 54 nM
|
|
|
CP0960671
|
3-(2-hydroxy-5-nitrophenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
Show/Hide
|
C16H11N3O5
|
1
|
1 |
IC50 = 56 nM
|
|
|
CP0500777
|
1-(2-Bromo-phenyl)-3-(3,4-dichloro-2-hydroxy-phenyl)-urea
Show/Hide
|
C13H9BrCl2N2O2
|
1
|
1 |
IC50 = 63 nM
|
|
|
CP0373671
|
7-chloro-3-(2-chloro-3-fluoro-phenylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C13H8Cl2FN3O3S
|
1
|
1 |
IC50 = 64 nM
|
|
|
CP0373709
|
3-(2-bromo-phenylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C13H9BrClN3O3S
|
1
|
1 |
IC50 = 64 nM
|
|
|
CP0960673
|
3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-N-ethyl-2-hydroxybenzamide
Show/Hide
|
C19H17N3O4
|
1
|
1 |
IC50 = 65 nM
|
|
|
CP0524363
|
7-bromo-3-(2-bromo-phenylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C13H9Br2N3O3S
|
1
|
1 |
IC50 = 70 nM
|
|
|
CP0910929
|
3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-4-hydroxybenzonitrile
Show/Hide
|
C17H11N3O3
|
1
|
1 |
IC50 = 74 nM
|
|
|
CP0374039
|
3-(2-(2-ethyl-2-(pyridin-2-yl)hydrazinyl)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C20H21N5O4
|
1
|
1 |
IC50 = 75 nM
|
|
|
CP0156021
|
3-(2-chloro-phenylamino)-7-nitro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C13H9ClN4O5S
|
1
|
1 |
IC50 = 81 nM
|
|
|
CP0405627
|
7-chloro-3-(2-chloro-phenylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C13H9Cl2N3O3S
|
1
|
1 |
IC50 = 92 nM
|
|
|
CP0501544
|
3-(2-(2-ethyl-2-(4-methoxyphenyl)hydrazinyl)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C22H24N4O5
|
1
|
1 |
IC50 = 100 nM
|
|
|
CP0462351
|
1-[4-chloro-3-(dimethylsulfamoyl)-2-hydroxyphenyl]-2-cyano-3-[2-(propan-2-yl)phenyl]guanidine
Show/Hide
|
C19H22ClN5O3S
|
1
|
1 |
IC50 = 112 nM
|
|
|
CP0918015
|
1-(3-Aminomethyl-4-chloro-2-hydroxy-phenyl)-3-(2-bromo-phenyl)-urea hydrochloride
Show/Hide
|
C14H14BrCl2N3O2
|
1
|
1 |
IC50 = 114 nM
|
|
|
CP0405621
|
3-(2-bromo-4-fluoro-phenylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C13H8BrClFN3O3S
|
1
|
1 |
IC50 = 120 nM
|
|
|
CP0950933
|
N-benzyl-3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxybenzamide
Show/Hide
|
C24H19N3O4
|
1
|
1 |
IC50 = 139 nM
|
|
|
CP0413175
|
5-[(2,3-difluorophenyl)sulfanylmethyl]-2-(furan-2-yl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C17H11F2N3O2S
|
1
|
1 |
IC50 = 150 nM
|
|
|
CP0960675
|
3-(3,4-dioxo-2-(tetrahydro-2H-pyran-4-ylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C18H21N3O5
|
1
|
1 |
IC50 = 171 nM
|
|
|
CP0495786
|
1-(4-Cyano-2-hydroxy-phenyl)-3-phenyl-urea
Show/Hide
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C14H11N3O2
|
1
|
1 |
IC50 = 200 nM
|
|
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CP0526491
|
3-(2-hydroxy-4-methylphenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
Show/Hide
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C17H14N2O3
|
1
|
1 |
IC50 = 205 nM
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|
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CP0405620
|
3-(biphenyl-2-ylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C19H14ClN3O3S
|
1
|
1 |
IC50 = 230 nM
|
|
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CP0897845
|
3-(2-hydroxyphenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
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C16H12N2O3
|
2
|
1 |
IC50 = 235 nM
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|
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2 |
IC50 = 476 nM
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CP0458373
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7-chloro-3-(2-methoxy-phenylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C14H12ClN3O4S
|
1
|
1 |
IC50 = 250 nM
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|
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CP0473432
|
2-[(2,3-difluorophenyl)sulfanylmethyl]-6H-pyrimido[1,2-b]indazol-4-one
Show/Hide
|
C17H11F2N3OS
|
1
|
1 |
IC50 = 260 nM
|
|
|
CP0464798
|
1-(3-cyano-2-hydroxyphenyl)-3-phenylurea
Show/Hide
|
C14H11N3O2
|
1
|
1 |
IC50 = 276 nM
|
|
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CP0458376
|
3-(2-bromo-phenylamino)-7-methyl-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C14H12BrN3O3S
|
1
|
1 |
IC50 = 280 nM
|
|
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CP0436080
|
5-[(2,3-difluorophenyl)sulfanylmethyl]-2-pyridin-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C18H12F2N4OS
|
1
|
1 |
IC50 = 280 nM
|
|
|
CP0372183
|
3-(2-hydroxy-5-methylphenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
Show/Hide
|
C17H14N2O3
|
1
|
1 |
IC50 = 308 nM
|
|
|
CP0495785
|
1-(2-Hydroxy-4-nitro-phenyl)-3-phenyl-urea
Show/Hide
|
C13H11N3O4
|
1
|
1 |
IC50 = 320 nM
|
|
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CP0515396
|
4-cyclopropyl-2-[(2,3-difluorophenyl)methylsulfanyl]-1H-pyrimidin-6-one
Show/Hide
|
C14H12F2N2OS
|
1
|
1 |
IC50 = 320 nM
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|
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CP0519744
|
2-benzyl-5-[(2,3-difluorophenyl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C19H14F2N4OS
|
2
|
1 |
IC50 = 330 nM
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|
|
2 |
IC50 = 350 nM
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|
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CP0372185
|
3-(2-hydroxy-6-nitrophenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
Show/Hide
|
C16H11N3O5
|
1
|
1 |
IC50 = 358 nM
|
|
|
CP0524364
|
3-(2-bromo-phenylamino)-7-fluoro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C13H9BrFN3O3S
|
1
|
1 |
IC50 = 360 nM
|
|
|
CP0541617
|
7-chloro-1,1-dioxo-3-o-tolylamino-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C14H12ClN3O3S
|
1
|
1 |
IC50 = 390 nM
|
|
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CP0414918
|
5-[(2,3-difluorophenyl)sulfanylmethyl]-2-(2-phenylethyl)-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C20H16F2N4OS
|
1
|
1 |
IC50 = 470 nM
|
|
|
CP0373672
|
3-(2-bromo-phenylamino)-8-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C13H9BrClN3O3S
|
1
|
1 |
IC50 = 480 nM
|
|
|
CP0458443
|
2-cyclohexyl-5-[(2,3-difluorophenyl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C18H18F2N4OS
|
1
|
1 |
IC50 = 510 nM
|
|
|
CP0550906
|
2-benzylsulfanyl-4-cyclopropyl-6-oxo-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C15H13N3OS
|
1
|
1 |
IC50 = 510 nM
|
|
|
CP0846917
|
(R)-3-(2-(2,3-dihydro-1H-inden-1-ylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C22H21N3O4
|
1
|
1 |
IC50 = 548 nM
|
|
|
CP0418239
|
2-[(2,3-difluorophenyl)methylsulfanyl]-4-(4-methoxyphenyl)-6-oxo-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C19H13F2N3O2S
|
1
|
1 |
IC50 = 710 nM
|
|
|
CP0456716
|
7-chloro-3-(2-fluoro-phenylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C13H9ClFN3O3S
|
1
|
1 |
IC50 = 740 nM
|
|
|
CP0489385
|
2-[(2,3-difluorophenyl)methylsulfanyl]-4-(4-hydroxyphenyl)-6-oxo-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C18H11F2N3O2S
|
1
|
1 |
IC50 = 780 nM
|
|
|
CP0521703
|
5-[(2,3-difluorophenyl)sulfanylmethyl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C13H9F2N3OS
|
1
|
1 |
IC50 = 810 nM
|
|
|
CP0517993
|
2-benzyl-5-(phenylsulfanylmethyl)-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C19H16N4OS
|
1
|
1 |
IC50 = 820 nM
|
|
|
CP0538400
|
7-chloro-1,1-dioxo-3-(2-trifluoromethyl-phenylamino)-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C14H9ClF3N3O3S
|
1
|
1 |
IC50 = 830 nM
|
|
|
CP0459197
|
3-(2-(2-ethyl-2-(4-fluorobenzoyl)hydrazinyl)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C22H21FN4O5
|
1
|
1 |
IC50 = 840 nM
|
|
|
CP0501543
|
3-(2-(2-ethyl-2-(4-fluorophenyl)hydrazinyl)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C21H21FN4O4
|
1
|
1 |
IC50 = 840 nM
|
|
|
CP0551846
|
5-[(2,3-difluorophenyl)sulfanylmethyl]-2-phenyl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C18H12F2N4OS
|
1
|
1 |
IC50 = 850 nM
|
|
|
CP0524705
|
5-[(2,3-difluorophenyl)sulfanylmethyl]-2-(3-methylfuran-2-yl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C18H13F2N3O2S
|
1
|
1 |
IC50 = 870 nM
|
|
|
CP0418215
|
2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-4-propan-2-yl-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C15H13F2N3OS
|
1
|
1 |
IC50 = 900 nM
|
|
|
CP0501346
|
1-(2-Bromo-phenyl)-3-(4-chloro-2-hydroxy-phenyl)-urea
Show/Hide
|
C13H10BrClN2O2
|
1
|
1 |
IC50 = 906 nM
|
|
|
CP0551847
|
5-[(2,3-difluorophenyl)sulfanylmethyl]-2-propan-2-yl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C15H14F2N4OS
|
1
|
1 |
IC50 = 910 nM
|
|
|
CP0940266
|
3-(3,4-dioxo-2-(phenethylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C21H21N3O4
|
1
|
1 |
IC50 = 926 nM
|
|
|
CP0503695
|
7-chloro-1,1-dioxo-3-(2-trifluoromethoxy-phenylamino)-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C14H9ClF3N3O4S
|
1
|
1 |
IC50 = 930 nM
|
|
|
CP0565509
|
1-(5-chloro-2-hydroxy-4-nitrophenyl)-3-phenylurea
Show/Hide
|
C13H10ClN3O4
|
1
|
1 |
IC50 = 950 nM
|
|
|
CP0940264
|
3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxybenzoic acid
Show/Hide
|
C17H12N2O5
|
1
|
1 |
IC50 = 1000 nM
|
|
|
CP0543144
|
5-[2-(2,3-difluorophenyl)ethyl]-2-(hydroxymethyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C15H13F2N3O2
|
1
|
1 |
IC50 = 1100 nM
|
|
|
CP0470434
|
3-(2-(2-acetyl-2-ethylhydrazinyl)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C17H20N4O5
|
1
|
1 |
IC50 = 1250 nM
|
|
|
CP0401442
|
2-[(2,3-difluorophenyl)methylsulfanyl]-4-(4-methylphenyl)-6-oxo-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C19H13F2N3OS
|
1
|
1 |
IC50 = 1400 nM
|
|
|
CP0571403
|
5-bromo-4-cyclopropyl-2-[(2,3-difluorophenyl)methylsulfanyl]-1H-pyrimidin-6-one
Show/Hide
|
C14H11BrF2N2OS
|
1
|
1 |
IC50 = 1400 nM
|
|
|
CP0469214
|
5-[(2,3-difluorophenyl)sulfanylmethyl]-2-methyl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C13H10F2N4OS
|
1
|
1 |
IC50 = 1500 nM
|
|
|
CP0541618
|
3-(2-bromo-6-fluoro-phenylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C13H8BrClFN3O3S
|
1
|
1 |
IC50 = 1600 nM
|
|
|
CP0508248
|
2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-4-(4-propan-2-yloxyphenyl)-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C21H17F2N3O2S
|
1
|
1 |
IC50 = 1600 nM
|
|
|
CP0415464
|
2-benzyl-5-[(3,4-difluorophenyl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C19H14F2N4OS
|
1
|
1 |
IC50 = 1700 nM
|
|
|
CP0473433
|
2-[(2,3-difluorophenyl)sulfanylmethyl]-7,8,9,10-tetrahydro-6H-pyrimido[1,2-b]indazol-4-one
Show/Hide
|
C17H15F2N3OS
|
1
|
1 |
IC50 = 1700 nM
|
|
|
CP0543145
|
2-benzyl-5-[(2,3-dichlorophenyl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C19H14Cl2N4OS
|
1
|
1 |
IC50 = 1700 nM
|
|
|
CP0385631
|
4-cyclobutyl-2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C16H13F2N3OS
|
1
|
1 |
IC50 = 1700 nM
|
|
|
CP0372184
|
3-(2-hydroxy-6-methylphenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
Show/Hide
|
C17H14N2O3
|
1
|
1 |
IC50 = 1720 nM
|
|
|
CP0524707
|
2-methyl-5-(phenylsulfanylmethyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C14H13N3OS
|
2
|
1 |
IC50 = 2000 nM
|
|
|
2 |
IC50 = 10300 nM
|
|
|
CP0433339
|
7-chloro-1,1-dioxo-3-phenylamino-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C13H10ClN3O3S
|
1
|
1 |
IC50 = 2400 nM
|
|
|
CP0539154
|
3-(2-bromo-phenylamino)-8-fluoro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C13H9BrFN3O3S
|
1
|
1 |
IC50 = 3000 nM
|
|
|
CP0955682
|
4-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-3-hydroxybenzoic acid
Show/Hide
|
C17H12N2O5
|
1
|
1 |
IC50 = 3100 nM
|
|
|
CP0550908
|
4-cyclopropyl-2-[(2,3-difluorophenyl)methylsulfanyl]-5-iodo-1H-pyrimidin-6-one
Show/Hide
|
C14H11F2IN2OS
|
1
|
1 |
IC50 = 3200 nM
|
|
|
CP0487910
|
4-tert-butyl-2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C16H15F2N3OS
|
1
|
1 |
IC50 = 3700 nM
|
|
|
CP0494468
|
2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-4-phenyl-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C18H11F2N3OS
|
1
|
1 |
IC50 = 3700 nM
|
|
|
CP0538401
|
3-(2-bromo-5-fluoro-phenylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C13H8BrClFN3O3S
|
1
|
1 |
IC50 = 3900 nM
|
|
|
CP0382022
|
2-benzyl-5-[(2,5-dimethylfuran-3-yl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C19H18N4O2S
|
1
|
1 |
IC50 = 4100 nM
|
|
|
CP0462349
|
2-benzyl-5-[[3-(4-methylphenyl)phenyl]sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C26H22N4OS
|
1
|
1 |
IC50 = 4100 nM
|
|
|
CP0551845
|
5-[(2,3-difluorophenyl)sulfanylmethyl]-7-oxo-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile
Show/Hide
|
C14H8F2N4OS
|
1
|
1 |
IC50 = 4100 nM
|
|
|
CP0487909
|
2-[(2,3-difluorophenyl)methylsulfanyl]-4-methyl-6-oxo-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C13H9F2N3OS
|
1
|
1 |
IC50 = 4300 nM
|
|
|
CP0413574
|
2-[(2,6-dichlorophenyl)methylsulfanyl]-6-oxo-4-phenyl-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C18H11Cl2N3OS
|
2
|
1 |
IC50 = 4300 nM
|
|
|
2 |
IC50 > 30000 nM
|
|
|
CP0522294
|
1-[2-(7-chloro-5-hydroxy-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-3-ylamino)-phenyl]-ethanone
Show/Hide
|
C15H12ClN3O4S
|
1
|
1 |
IC50 = 4500 nM
|
|
|
CP0489384
|
2-[(2,3-difluorophenyl)methylsulfanyl]-4-(4-methoxy-3-methylphenyl)-6-oxo-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C20H15F2N3O2S
|
1
|
1 |
IC50 = 4600 nM
|
|
|
CP0385741
|
2-[(2,3-difluorophenyl)methylsulfanyl]-4-(3-methylphenyl)-6-oxo-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C19H13F2N3OS
|
1
|
1 |
IC50 = 4700 nM
|
|
|
CP0539019
|
2-benzyl-5-[(2,4-dichlorophenyl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C19H14Cl2N4OS
|
1
|
1 |
IC50 = 4800 nM
|
|
|
CP0515395
|
4-cyclopropyl-6-oxo-2-(1-phenylethylsulfanyl)-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C16H15N3OS
|
1
|
1 |
IC50 = 4800 nM
|
|
|
CP0566173
|
4-cyclopentyl-2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C17H15F2N3OS
|
1
|
1 |
IC50 = 4900 nM
|
|
|
CP0522295
|
3-(4-bromo-phenylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C13H9BrClN3O3S
|
1
|
1 |
IC50 = 5100 nM
|
|
|
CP0458372
|
3-(2-chloro-phenylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C13H10ClN3O3S
|
1
|
1 |
IC50 = 5200 nM
|
|
|
CP0433340
|
3-(3-bromo-phenylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C13H9BrClN3O3S
|
1
|
1 |
IC50 = 6100 nM
|
|
|
CP0384488
|
3-(2-(2-ethyl-2-(4-fluorobenzyl)hydrazinyl)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C22H23FN4O4
|
1
|
1 |
IC50 = 6340 nM
|
|
|
CP0418322
|
2-benzyl-5-[[3-(trifluoromethoxy)phenyl]sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C20H15F3N4O2S
|
1
|
1 |
IC50 = 6400 nM
|
|
|
CP0379277
|
4-cyclopropyl-6-oxo-2-(2-phenylpropan-2-ylsulfanyl)-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C17H17N3OS
|
1
|
1 |
IC50 = 6400 nM
|
|
|
CP0940265
|
2-hydroxy-N,N-dimethyl-3-(2-(methyl(phenyl)amino)-3,4-dioxocyclobut-1-enylamino)benzamide
Show/Hide
|
C20H19N3O4
|
1
|
1 |
IC50 = 7200 nM
|
|
|
CP0385632
|
4-(4-chlorophenyl)-2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-1H-pyrimidine-5-carbonitrile
Show/Hide
|
C18H10ClF2N3OS
|
1
|
1 |
IC50 = 7400 nM
|
|
|
CP0538326
|
2-benzyl-5-[(4-chloro-2,5-dimethylphenyl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C21H19ClN4OS
|
1
|
1 |
IC50 = 7800 nM
|
|
|
CP0433341
|
3-benzylamino-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
|
C14H12ClN3O3S
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1
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1 |
IC50 = 8000 nM
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CP0845752
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3-(4-nitrophenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
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C16H11N3O4
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1
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1 |
IC50 = 8600 nM
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CP0550907
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4-cyclopropyl-2-[(2,3-difluorophenyl)sulfanylmethyl]-6-oxo-1H-pyrimidine-5-carbonitrile
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C15H11F2N3OS
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1
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1 |
IC50 = 10000 nM
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CP0418349
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[5-[2-(2,3-difluorophenyl)ethyl]-7-methoxypyrazolo[1,5-a]pyrimidin-2-yl]methanol
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C16H15F2N3O2
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1
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1 |
IC50 = 10500 nM
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CP0434086
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2-benzyl-5-[(4-phenyl-1,3-thiazol-2-yl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
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C22H17N5OS2
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1
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1 |
IC50 = 11000 nM
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CP0524706
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2-benzyl-5-[(2,4-dimethoxyphenyl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
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C21H20N4O3S
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1
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1 |
IC50 = 11000 nM
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CP0521704
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2-[(2-benzyl-7-oxo-1H-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl)methylsulfanyl]pyridine-3-carbonitrile
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C19H14N6OS
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1
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1 |
IC50 = 13000 nM
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CP0382020
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N-[2-benzyl-5-[(2,3-difluorophenyl)sulfanylmethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]methanesulfonamide
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C20H17F2N5O2S2
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1
|
1 |
IC50 = 13900 nM
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CP0522296
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3-((R)-sec-butylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
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C11H14ClN3O3S
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1
|
1 |
IC50 = 15000 nM
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CP0405681
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7-chloro-3-cyclopentylamino-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
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C12H14ClN3O3S
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1
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1 |
IC50 = 20000 nM
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CP0551844
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5-[(2,3-difluorophenyl)sulfanylmethyl]-3-ethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
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C15H13F2N3OS
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1
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1 |
IC50 = 20000 nM
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CP0565510
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1-(2-hydroxy-4-methylphenyl)-3-phenylurea
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C14H14N2O2
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1
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1 |
IC50 = 25000 nM
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CP0562098
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3-((2-hydroxyphenyl)(methyl)amino)-4-(phenylamino)cyclobut-3-ene-1,2-dione
Show/Hide
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C17H14N2O3
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1
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1 |
IC50 = 28600 nM
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CP0427950
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1-(2-hydroxy-6-nitrophenyl)-3-phenylurea
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C13H11N3O4
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1
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1 |
IC50 > 30000 nM
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CP0444712
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1-(2-Hydroxy-phenyl)-3-phenyl-urea
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C13H12N2O2
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1
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1 |
IC50 > 30000 nM
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CP0515184
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1-(5-chloro-2-hydroxyphenyl)-3-phenylurea
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C13H11ClN2O2
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1
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1 |
IC50 > 30000 nM
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CP0524262
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1-(2-hydroxy-6-methylphenyl)-3-phenylurea
Show/Hide
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C14H14N2O2
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1
|
1 |
IC50 > 30000 nM
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CP0526489
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1-(2-hydroxy-5-methylphenyl)-3-phenylurea
Show/Hide
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C14H14N2O2
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1
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1 |
IC50 > 30000 nM
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CP0503694
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2-(7-chloro-5-hydroxy-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-3-ylamino)-benzoic acid
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C14H10ClN3O5S
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1
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1 |
IC50 > 30000 nM
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CP0503696
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7-chloro-3-(2-chloro-benzylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
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C14H11Cl2N3O3S
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1
|
1 |
IC50 > 30000 nM
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CP0533073
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7-chloro-3-(2-morpholin-4-yl-phenylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol
Show/Hide
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C17H17ClN4O4S
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1
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1 |
IC50 > 30000 nM
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CP0457363
|
2-benzyl-5-[(1-propylimidazol-2-yl)sulfanylmethyl]-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
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C19H20N6OS
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1
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1 |
IC50 > 30000 nM
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CP0462350
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2-benzyl-5-(pentylsulfanylmethyl)-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
Show/Hide
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C18H22N4OS
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1
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1 |
IC50 > 30000 nM
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CP0463579
|
2-[(2,3-difluorophenyl)methylsulfanyl]-4-[(1-hydroxy-2-methylpropan-2-yl)amino]-6-phenylpyrimidine-5-carbonitrile
Show/Hide
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C22H20F2N4OS
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1
|
1 |
IC50 > 30000 nM
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CP0480518
|
4-cyclopropyl-6-oxo-2-(phenylsulfanylmethyl)-1H-pyrimidine-5-carbonitrile
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C15H13N3OS
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1
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1 |
IC50 > 30000 nM
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CP0574678
|
N-[5-cyano-2-[(2,3-difluorophenyl)methylsulfanyl]-6-phenylpyrimidin-4-yl]methanesulfonamide
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C19H14F2N4O2S2
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1
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1 |
IC50 > 30000 nM
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CP0372181
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1-(2-bromophenyl)-3-(2-hydroxyphenyl)urea
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C13H11BrN2O2
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1
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1 |
IC50 > 9000 nM
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CP0862453
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N-(4-chloro-2-hydroxy-3-{[(3-exo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]sulfonyl}phenyl)-N'-(3-fluoro-2-methylphenyl)urea
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C22H25ClFN3O4S
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1
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1 |
IC50 < 30000 nM
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CP0862454
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N-{4-chloro-2-hydroxy-3-[(3S)-3-pyrrolidinylsulfonyl]-phenyl}-N'-(3-fluoro-2-methylphenyl)urea
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C18H19ClFN3O4S
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1
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1 |
IC50 < 30000 nM
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CP0862455
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N-{4-chloro-2-hydroxy-3-[3-pyrrolidinylmethyl)sulfonyl]-phenyl}-N'-{2-[(trifluoromethyl)oxy]phenyl}-urea
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C19H19ClF3N3O5S
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1
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1 |
IC50 < 30000 nM
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CP0862458
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N-{3-[(1R,5S)-8-azabicyclo[3.2.1]oct-3-yisulfonyl]-4-chloro-2-hydroxyphenyl}-N'-(3-fluoro-2-methylphenyl)urea
Show/Hide
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C21H23ClFN3O4S
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1
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1 |
IC50 < 30000 nM
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CP0862459
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N-(2-chloro-3-fluorophenyl)-N'-{4-chloro-2-hydroxy-3-[(3S)-3-piperidinylsulfonyl]phenyl}urea
Show/Hide
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C18H18Cl2FN3O4S
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1
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1 |
IC50 < 30000 nM
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CP0862460
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N-[4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl-)phenyl]-N'-(2-chloro-3-pyridinyl)urea
Show/Hide
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C17H18Cl2N4O4S
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1
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1 |
IC50 < 30000 nM
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CP0862481
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N-(2-chloro-3-fluorophenyl)-N'-{4-chloro-2-hydroxy-3-[(3R)-pyrrolidinylsulfonyl]-phenyl}urea
Show/Hide
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C17H16Cl2FN3O4S
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1
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1 |
IC50 < 30000 nM
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CP0903454
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N-[4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl)-phenyl]-N'-(3-fluoro-2-methylphenyl)urea
Show/Hide
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C19H21ClFN3O4S
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1
|
1 |
IC50 < 30000 nM
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CP0903457
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N-[4-chloro-2-hydroxy-3-(4-piperidinylsulfonyl)-phenyl]-N'-(2,2-difluoro-1,3-benzodioxol-4-yl)urea
Show/Hide
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C19H18ClF2N3O6S
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1
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1 |
IC50 < 30000 nM
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CP0903458
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N-{4-chloro-2-hydroxy-3-[(3S)-3-pyrrolidinylsulfonyl]-phenyl}-N'-(2-chloro-3-pyridinyl)urea
Show/Hide
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C16H16Cl2N4O4S
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1
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1 |
IC50 < 30000 nM
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CP0903459
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Ethyl 4-({6-chloro-2-hydroxy-3-[({[2-(phenylox-y)phenyl]amino}carbonyl)amino]phenyl}sulfonyl)-1-piperidinecarboxylate
Show/Hide
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C27H28ClN3O7S
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1
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1 |
IC50 < 30000 nM
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CP0903460
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N-{4-chloro-2-hydroxy-3-[(3R)-3-pyrrolidinylsulfonyl]-phenyl}-N'-(2-ethylphenyl)urea
Show/Hide
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C19H22ClN3O4S
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1
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1 |
IC50 < 30000 nM
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CP0903461
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N-(2-chloro-3-fluorophenyl)-N'-[4-chloro-2-hydroxy-3-(4-piperidinylsulfonyl)-phenyl)urea
Show/Hide
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C18H18Cl2FN3O4S
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1
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1 |
IC50 < 30000 nM
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CP0903462
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N-{3-[(1R,5S)-8-azabicyclo[3.2.1]oct-3-ylsulfonyl]-4-chloro-2-hydroxyphenyl}-N'-(2-chloro-3-pyridinyl)urea
Show/Hide
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C19H20Cl2N4O4S
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1
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1 |
IC50 < 30000 nM
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CP0903463
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N-[4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl)-phenyl]-N'-{2-[(trifluoromethyl)oxy]-phenyljurea
Show/Hide
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C19H19ClF3N3O5S
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1
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1 |
IC50 < 30000 nM
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CP0920833
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N-[4-chloro-2-hydroxy-3-(4-piperidinylsulfonyl)-phenyl]-N'-(2-ethylphenyl)urea
Show/Hide
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C20H24ClN3O4S
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1
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1 |
IC50 < 30000 nM
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CP0920834
|
ethyl4-{[6-chloro-3-({[(3-fluoro-2-methylphenyl)amino]-carbonyljamino]-2-hydroxyphenyl[sulfonyl}-1-piperidinecarboxylate
Show/Hide
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C22H25ClFN3O6S
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1
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1 |
IC50 < 30000 nM
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CP0920835
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N-{3-[(1R,5S)-8-azabicyclo[3.2.1]oct-3-yl]sulfonyl]-4-chloro-2-hydroxyphenyl}-N'-[2-(phenyloxy)phenyl)urea
Show/Hide
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C26H26ClN3O5S
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1
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1 |
IC50 < 30000 nM
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CP0920836
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N-{4-chloro-2-hydroxy-3-[(3R)-3-pyrrolidinylsulfonyl]-phenyl}-N'-(2,2-difluoro-1,3-benzodioxol-4-yl)urea
Show/Hide
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C18H16ClF2N3O6S
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1
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1 |
IC50 < 30000 nM
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CP0920837
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N-[4-chloro-2-hydroxy-3-(4-piperidinylsulfonyl)-phenyl]-N'-(3-fluoro-2-methylphenyl)urea
Show/Hide
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C19H21ClFN3O4S
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1
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1 |
IC50 < 30000 nM
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CP0920838
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N-[4-chloro-2-hydroxy-3-(4-piperidinylsulfonyl)-phenyl]-N'-(2-chloro-3-pyridinyl)urea
Show/Hide
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C17H18Cl2N4O4S
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1
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1 |
IC50 < 30000 nM
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CP0920839
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N-{3-[(lR,5S)-8-azabicyclo[3.2.1]oct-3-yl]sulfonyl]-4-chloro-2-hydroxyphenyl}-N'-(2-chloro-3-fluorophenyl)urea
Show/Hide
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C20H20Cl2FN3O4S
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1
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1 |
IC50 < 30000 nM
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CP0921071
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N-[4-chloro-2-hydroxy-3-(4-piperidinylsulfonyl)-phenyl]-N'-{2-[(tritluoromethyl)oxyj-phenyl)urea
Show/Hide
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C19H19ClF3N3O5S
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1
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1 |
IC50 < 30000 nM
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CP0921715
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N-{4-chloro-2-hydroxy-3-[(3S)-3-piperidinylsulfonyl]phenyl}-N'-(2-chloro-3-pyridinyl)urea
Show/Hide
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C17H18Cl2N4O4S
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1
|
1 |
IC50 < 30000 nM
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|
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CP0921716
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N-[4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl)-phenyl]-N'-(2,3-dichlorophenyl)urea
Show/Hide
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C18H18Cl3N3O4S
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1
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1 |
IC50 < 30000 nM
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CP0921717
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N-{4-chloro-2-hydroxy-3-[(3S)-3-pyrrolidinylsulfonyl]-phenyl}-N'-[2-(phenyloxy)phenyl]urea
Show/Hide
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C23H22ClN3O5S
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1
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1 |
IC50 < 30000 nM
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CP0921718
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N-[4-chloro-2-hydroxy-3-(4-piperidinylsulfo-nyl)phenyl]-N'-[2-(phenyloxy)phenyl]urea
Show/Hide
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C24H24ClN3O5S
|
1
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1 |
IC50 < 30000 nM
|
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CP0921719
|
DANIRIXIN
Show/Hide
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C19H21ClFN3O4S
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1
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1 |
IC50 < 30000 nM
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CP0921720
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N-[3-(3-azetidinylsulfonyl)-4-chloro-2-hydroxyphenyl]-N'-(2-chloro-3-pyridinyl)urea
Show/Hide
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C15H14Cl2N4O4S
|
1
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1 |
IC50 < 30000 nM
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CP0921721
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N-[4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl)-phenyl]-N'-(2-ethylphenyl)urea
Show/Hide
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C20H24ClN3O4S
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1
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1 |
IC50 < 30000 nM
|
|
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CP0922634
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N-{4-chloro-2-hydroxy-3-[(3R)-3-pyrrolidinylsulfonyl]-phenyl}-N'-(2-(trifluoromethyl)oxy]-phenyl)urea
Show/Hide
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C18H17ClF3N3O5S
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1
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1 |
IC50 < 30000 nM
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CP0923161
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N-{4-chloro-2-hydroxy-3-[(3-pyrrolidinylmethyl)-sulfonyl]phenyl}-N'-(3-fluoro-2-methylphenyl)urea
Show/Hide
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C19H21ClFN3O4S
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1
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1 |
IC50 < 30000 nM
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CP0928820
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N-(2-chloro-3-fluorophenyl)-N'-{4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl)-phenyl)urea
Show/Hide
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C18H18Cl2FN3O4S
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1
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1 |
IC50 < 30000 nM
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|
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CP0930310
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N-(2-chloro-3-fluorophenyl)-N'-{4-chloro-2-hydroxy-3-[(3-pyrrolidinylmethyl)-sulfonyl]phenyl}urea
Show/Hide
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C18H18Cl2FN3O4S
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1
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1 |
IC50 < 30000 nM
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CP0943508
|
ethyl4-{[6-chloro-3-({[(2-chloro-3-fluorophenyl)amino]-carbonyljamino]-2-hydroxyphenyl[sulfonyl}-1-piperidinecarboxylate
Show/Hide
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C21H22Cl2FN3O6S
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1
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1 |
IC50 < 30000 nM
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CP0947357
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N-[3-(3-azetidinylsulfonyl)-4-chloro-2-hydroxyphenyl]-N'-(3-fluoro-3-methylphenyl)urea
Show/Hide
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C17H17ClFN3O4S
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1
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1 |
IC50 < 30000 nM
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CP0947358
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N-(2-chloro-3-fluorophenyl)-N'-{4-chloro-2-hydroxy-3-[(3S)-3-pyrrolidinylsulfonyl]-phenyl)urea
Show/Hide
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C17H16Cl2FN3O4S
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1
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1 |
IC50 < 30000 nM
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CP0952635
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N-[3-(3-azetidinylsulfonyl)-4-chloro-2-hydroxyphenyl]-N'-(2-chloro-3-fluorophenyl)urea
Show/Hide
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C16H14Cl2FN3O4S
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1
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1 |
IC50 < 30000 nM
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CP0471149
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3-(2-((R)-1-(4-sec-butylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C24H29N3O5
|
1
|
1 |
Ki = 0.6 nM
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|
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CP0444765
|
(R)-3-(3,4-dioxo-2-(1-(4-(pentan-3-yl)furan-2-yl)propylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C25H31N3O5
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1
|
1 |
Ki = 0.8 nM
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|
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CP0502070
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(R)-3-(2-(1-(4-ethylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
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C22H25N3O5
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1
|
1 |
Ki = 1 nM
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CP0467181
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(R)-2-hydroxy-3-(2-(1-(4-isopropylfuran-2-yl)ethylamino)-3,4-dioxocyclobut-1-enylamino)-N,N-dimethylbenzamide
Show/Hide
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C22H25N3O5
|
1
|
1 |
Ki = 2 nM
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|
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CP0528071
|
(R)-3-(2-(1-(4-butylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C24H29N3O5
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1
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1 |
Ki = 2 nM
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|
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CP0461709
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(R)-3-(2-(1-(4-cyclopentylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C25H29N3O5
|
1
|
1 |
Ki = 3 nM
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|
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CP0467184
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(R)-3-(2-(cyclopropyl(4-isopropylfuran-2-yl)methylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C24H27N3O5
|
1
|
1 |
Ki = 3 nM
|
|
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CP0457569
|
(R)-3-(2-(1-(4-cyclohexylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
|
C26H31N3O5
|
1
|
1 |
Ki = 4 nM
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|
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CP0461707
|
(R)-2-hydroxy-3-(2-(1-(4-isopropylfuran-2-yl)-2-methylpropylamino)-3,4-dioxocyclobut-1-enylamino)-N,N-dimethylbenzamide
Show/Hide
|
C24H29N3O5
|
1
|
1 |
Ki = 4 nM
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|
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CP0467179
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(R)-2-hydroxy-3-(2-(1-(4-isopropylfuran-2-yl)-2,2-dimethylpropylamino)-3,4-dioxocyclobut-1-enylamino)-N,N-dimethylbenzamide
Show/Hide
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C25H31N3O5
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1
|
1 |
Ki = 4 nM
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CP0467183
|
(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(4-methylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide
Show/Hide
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C21H23N3O5
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1
|
1 |
Ki = 4 nM
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CP0485168
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(R)-3-(2-(1-(4-tert-butylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Show/Hide
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C24H29N3O5
|
1
|
1 |
Ki = 4 nM
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|
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CP0052095
|
(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide
Show/Hide
|
C21H23N3O5
|
1
|
1 |
Ki = 5 nM
|
|
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CP0467185
|
(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(4-methylthiophen-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide
Show/Hide
|
C21H23N3O4S
|
1
|
1 |
Ki = 5 nM
|
|
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CP0500390
|
(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylthiophen-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide
Show/Hide
|
C21H23N3O4S
|
1
|
1 |
Ki = 5 nM
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CP0453928
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(S)-3-(3,4-dioxo-2-(2,2,2-trifluoro-1-(4-isopropylfuran-2-yl)ethylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
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C22H22F3N3O5
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1
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1 |
Ki = 6 nM
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CP0461711
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(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(4-(4-morpholinobutyl)furan-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide
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C28H36N4O6
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1
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1 |
Ki = 9 nM
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CP0542184
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(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(3-methylthiophen-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide
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C21H23N3O4S
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1
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1 |
Ki = 10 nM
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CP0407923
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(2S)-2-(6-butyl-2-(4-(4-(trifluoromethyl)phenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C29H39F3N6O2
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1
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1 |
Ki = 14 nM
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CP0432128
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(2S)-2-(6-butyl-2-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C29H39F3N6O3
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1
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1 |
Ki = 17 nM
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CP0458492
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(R)-3-(2-(1-(3-ethylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
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C22H25N3O5
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1
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1 |
Ki = 25 nM
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CP0485592
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(2S)-N-(3-ethoxypropyl)-4-methyl-2-(6-propyl-2-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)pentanamide
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C28H37F3N6O3
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1
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1 |
Ki = 25 nM
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CP0522677
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(2S)-2-(6-butyl-2-(4-(4-chlorophenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C28H39ClN6O2
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1
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1 |
Ki = 27 nM
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CP0435302
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(2S)-2-(6-butyl-2-(4-(4-hydroxyphenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C28H40N6O3
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1
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1 |
Ki = 32 nM
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CP0394245
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(2S)-N-(3-ethoxypropyl)-4-methyl-2-(6-propyl-2-(4-(3-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)pentanamide
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C28H37F3N6O3
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1
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1 |
Ki = 35 nM
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CP0445644
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(2S)-2-(6-butyl-2-(4-(4-fluorophenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C28H39FN6O2
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1
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1 |
Ki = 37 nM
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CP0559378
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(2S)-2-(6-butyl-2-(4-p-tolyl-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C29H42N6O2
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1
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1 |
Ki = 40 nM
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CP0432130
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(2S)-2-(6-butyl-2-(4-(4-methoxyphenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C29H42N6O3
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1
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1 |
Ki = 42 nM
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CP0424977
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(2S)-2-(6-butyl-2-(4-(4-cyanophenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C29H39N7O2
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1
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1 |
Ki = 43 nM
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CP0525972
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(2S)-N-(3-ethoxypropyl)-4-methyl-2-(6-methyl-2-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)pentanamide
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C26H33F3N6O3
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1
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1 |
Ki = 44 nM
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CP0435538
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(2S)-N-(3-ethoxypropyl)-4-methyl-2-(6-propyl-2-(4-(2-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)pentanamide
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C28H37F3N6O3
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1
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1 |
Ki = 50 nM
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CP0436976
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(2S)-N-(3-ethoxypropyl)-2-(6-ethyl-2-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)-4-methylpentanamide
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C27H35F3N6O3
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1
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1 |
Ki = 57 nM
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CP0407922
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(2S)-2-(2-(1H-imidazol-1-yl)-6-(octylthio)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C26H44N6O2S
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1
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1 |
Ki = 60 nM
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CP0424820
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(2S)-2-(6-butyl-2-(4-tert-butyl-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C26H44N6O2
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1
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1 |
Ki = 85 nM
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CP0432835
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(2S)-2-(6-butyl-2-(4-methyl-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C23H38N6O2
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1
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1 |
Ki = 90 nM
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CP0552169
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(2S)-2-(6-butyl-2-(4-phenyl-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C28H40N6O2
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1
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1 |
Ki = 100 nM
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CP0436979
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(2S)-2-(2-(1H-imidazol-1-yl)-6-octylpyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C26H44N6O2
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1
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1 |
Ki = 120 nM
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CP0435539
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(2S)-2-(6-butyl-2-(4-(4-nitrophenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C28H39N7O4
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1
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1 |
Ki = 160 nM
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CP0432127
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(2S)-N-(3-ethoxypropyl)-4-methyl-2-(2-(4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)pyrimidin-4-ylamino)pentanamide
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C25H31F3N6O3
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1
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1 |
Ki = 200 nM
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CP0432132
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(2S)-N-(3-ethoxypropyl)-2-(6-hexyl-2-(1H-imidazol-1-yl)pyrimidin-4-ylamino)-4-methylpentanamide
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C24H40N6O2
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1
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1 |
Ki = 290 nM
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CP0516395
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(2S)-2-(2-(4-(4-aminophenyl)-1H-imidazol-1-yl)-6-butylpyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C28H41N7O2
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1
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1 |
Ki = 600 nM
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CP0559379
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(2S)-2-(6-butyl-2-(pyridin-3-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C24H37N5O2
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1
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1 |
Ki = 750 nM
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CP0407924
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(2S)-2-(6-butyl-2-(1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C22H36N6O2
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1
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1 |
Ki = 1700 nM
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CP0485846
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(2S)-2-(6-tert-butyl-2-(1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C22H36N6O2
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1
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1 |
Ki = 6000 nM
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CP0442167
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(2S)-2-(6-butyl-2-(1H-1,2,4-triazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C21H35N7O2
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1
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1 |
Ki > 10000 nM
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CP0562163
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(2S)-2-(6-butyl-2-(2-methyl-1H-imidazol-1-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C23H38N6O2
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1
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1 |
Ki > 10000 nM
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CP0435541
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(S)-2-(6-butyl-2-(pyridin-4-yl)pyrimidin-4-ylamino)-N-(3-ethoxypropyl)-4-methylpentanamide
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C24H37N5O2
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1
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1 |
Ki > 5000 nM
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