General Information of the Compound
Compound ID
CP0394699
Compound Name
3-[3-(2-Bromo-phenyl)-ureido]-6-chloro-2-hydroxy-benzenesulfonamide
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Structure
Formula
C13H11BrClN3O4S
Molecular Weight
420.672
Canonical SMILES
NS(=O)(=O)c1c(Cl)ccc(NC(=O)Nc2ccccc2Br)c1O
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InChI
InChI=1S/C13H11BrClN3O4S/c14-7-3-1-2-4-9(7)17-13(20)18-10-6-5-8(15)12(11(10)19)23(16,21)22/h1-6,19H,(H2,16,21,22)(H2,17,18,20)
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InChIKey
GDYZJBDAHGMIIH-UHFFFAOYSA-N
Physicochemical Property
logP
3.0995
Rotatable Bonds
3
Heavy Atom Count
23
Polar Areas
121.52
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
4
Complexity
23

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 9888410
SID: 14855992
ChEMBL ID
CHEMBL359670
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01304, C-X-C chemokine receptor type 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1366 nM
   TI
   LI
   LO
   TS
Protein ID: PT01013, C-X-C chemokine receptor type 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS