Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(2,3-difluorophenyl)methylsulfanyl]-4-[(1-hydroxy-2-methylpropan-2-yl)amino]-6-phenylpyrimidine-5-carbonitrile
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 PubChem ID
CID: 118706788
Canonical SMILES
CC(C)(CO)Nc1nc(SCc2cccc(F)c2F)nc(-c2ccccc2)c1C#N
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Compound Formula C22H20F2N4OS
Compound Structure
Protein Name
 Protein Info 
C-X-C chemokine receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CXC chemokine receptor
Uniprot ID
P25025
Gene Name
CXCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 > 30000 nM
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   LI
   LO
   TS