Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-cyclopropyl-2-[(2,3-difluorophenyl)methylsulfanyl]-6-oxo-1H-pyrimidine-5-carbonitrile
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 PubChem ID
CID: 135907764
SID: 56253065
Canonical SMILES
Oc1nc(SCc2cccc(F)c2F)nc(C2CC2)c1C#N
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Compound Formula C15H11F2N3OS
Compound Structure
Protein Name
 Protein Info 
C-X-C chemokine receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CXC chemokine receptor
Uniprot ID
P25025
Gene Name
CXCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
2
IC50 = 140 nM
   TI
   LI
   LO
   TS