Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(4-chloro-2-hydroxy-3-(4-methyl-1,4-diazepan-1-ylsulfonyl)phenylamino)-4-(2-chlorophenylamino)cyclobut-3-ene-1,2-dione hydrochloride
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 PubChem ID
CID: 45263585
Canonical SMILES
CN1CCCN(S(=O)(=O)c2c(Cl)ccc(Nc3c(Nc4ccccc4Cl)c(=O)c3=O)c2O)CC1.Cl
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Compound Formula C22H23Cl3N4O5S
Compound Structure
Protein Name
 Protein Info 
C-X-C chemokine receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CXC chemokine receptor
Uniprot ID
P25025
Gene Name
CXCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 20 nM
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   LI
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   TS