Brief Information of the Compound and Protein
Compound Name
2-benzylsulfanyl-4-cyclopropyl-6-oxo-1H-pyrimidine-5-carbonitrile
    Show/Hide
PubChem ID
CID: 135964204
Canonical SMILES
Oc1nc(SCc2ccccc2)nc(C2CC2)c1C#N
    Show/Hide
Compound Formula C15H13N3OS
Compound Structure
Protein Name
C-X-C chemokine receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CXC chemokine receptor
Uniprot ID
P25025
Gene Name
CXCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 510 nM
   TI
   LI
   LO
   TS