Brief Information of the Compound and Protein
Compound Name
2-methyl-5-(phenylsulfanylmethyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
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Canonical SMILES
Cc1cc2nc(CSc3ccccc3)cc(O)n2n1
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Compound Formula C14H13N3OS
Compound Structure
Protein Name
C-X-C chemokine receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CXC chemokine receptor
Uniprot ID
P25025
Gene Name
CXCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
2
IC50 = 10300 nM
   TI
   LI
   LO
   TS