Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT02663 , Nuclear receptor ROR-gamma
Gene Name RORC
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P51449
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT02663
 
Compound ID Compound Name Compound Formula
CP0534361
4-[[(2S)-6-[3-(difluoromethoxy)-5-fluorophenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]methyl]oxane-4-carboxylic acid
   Show/Hide
C29H25F6NO7S
 1
1
EC50 = 58 nM
   TI
   LI
   LO
   TS
CP0420011
3-[(2S)-6-[3-(difluoromethoxy)-5-fluorophenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C25H19F6NO6S
 1
1
EC50 = 76 nM
   TI
   LI
   LO
   TS
CP0487451
3-[(2S)-6-(3-chloro-2-fluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]-2,2-dimethylpropanoic acid
   Show/Hide
C26H22ClF4NO5S
 1
1
EC50 = 79 nM
   TI
   LI
   LO
   TS
CP0138560
4-[[(2S)-6-(3-chloro-2-fluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]methyl]oxane-4-carboxylic acid
   Show/Hide
C28H24ClF4NO6S
 1
1
EC50 = 103 nM
   TI
   LI
   LO
   TS
CP0060756
3-[(2S)-6-[3-(difluoromethoxy)-5-fluorophenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]-2,2-dimethylpropanoic acid
   Show/Hide
C27H23F6NO6S
 1
1
EC50 = 120 nM
   TI
   LI
   LO
   TS
CP0471268
3-[(2S)-6-(2-chloro-3,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C24H17ClF5NO5S
 1
1
EC50 = 120 nM
   TI
   LI
   LO
   TS
CP0420013
3-[[(2S)-6-[3-(difluoromethoxy)-5-fluorophenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]methyl]oxetane-3-carboxylic acid
   Show/Hide
C27H21F6NO7S
 1
1
EC50 = 123 nM
   TI
   LI
   LO
   TS
CP0552378
3-[(2S)-6-(2-chloro-5-fluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C24H18ClF4NO5S
 1
1
EC50 = 124 nM
   TI
   LI
   LO
   TS
CP0351090
(2R)-3-[(2S)-6-(2,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]-2-methylpropanoic acid
   Show/Hide
C25H20F5NO5S
 1
1
EC50 = 126 nM
   TI
   LI
   LO
   TS
CP0553547
3-[(2S)-6-(2-chloro-3-fluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C24H18ClF4NO5S
 1
1
EC50 = 144 nM
   TI
   LI
   LO
   TS
CP0552370
(2R)-4-[(2S)-6-(2,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]-2-hydroxybutanoic acid
   Show/Hide
C25H20F5NO6S
 1
1
EC50 = 166 nM
   TI
   LI
   LO
   TS
CP0549139
3-[(2S)-6-(3,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C24H18F5NO5S
 1
1
EC50 = 174 nM
   TI
   LI
   LO
   TS
CP0471269
3-[[(2S)-6-(2,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]methyl]oxetane-3-carboxylic acid
   Show/Hide
C26H20F5NO6S
 1
1
EC50 = 179 nM
   TI
   LI
   LO
   TS
CP0534099
3-[(2S)-6-(2,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C24H18F5NO5S
 1
1
EC50 = 181 nM
   TI
   LI
   LO
   TS
CP0471267
3-[(2S)-6-(3-methoxyphenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C25H22F3NO6S
 1
1
EC50 = 197 nM
   TI
   LI
   LO
   TS
CP0189596
3-[(2S)-6-[(E)-2-(2-chloro-6-fluorophenyl)prop-1-enyl]-4-[(2-ethoxy-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)sulfonyl]-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C29H31ClFN3O6S
 1
1
EC50 = 199 nM
   TI
   LI
   LO
   TS
CP0552379
3-[(2S)-6-(3-fluoro-5-methoxyphenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C25H21F4NO6S
 1
1
EC50 = 217 nM
   TI
   LI
   LO
   TS
CP0138637
3-[(2S)-6-[(E)-2-[2-chloro-6-(trifluoromethyl)phenyl]ethenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C27H20ClF6NO5S
 1
1
EC50 = 229 nM
   TI
   LI
   LO
   TS
CP0564257
3-[(2S)-6-[3-(difluoromethoxy)phenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C25H20F5NO6S
 1
1
EC50 = 278 nM
   TI
   LI
   LO
   TS
CP0471271
3-[(2S)-6-[(E)-2-(2-chloro-6-fluorophenyl)prop-1-enyl]-4-[3-(difluoromethoxy)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C27H23ClF3NO6S
 1
1
EC50 = 280 nM
   TI
   LI
   LO
   TS
CP0534098
3-[(2S)-6-[(E)-2-(2-methylphenyl)prop-1-enyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C28H26F3NO5S
 1
1
EC50 = 285 nM
   TI
   LI
   LO
   TS
CP0552372
3-[(2S)-6-[(E)-2-[2-(trifluoromethyl)phenyl]prop-1-enyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C28H23F6NO5S
 1
1
EC50 = 290 nM
   TI
   LI
   LO
   TS
CP0546383
3-[(2S)-6-(3-chlorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C24H19ClF3NO5S
 1
1
EC50 = 309 nM
   TI
   LI
   LO
   TS
CP0471263
3-[(2S)-6-[(E)-2-(2-chloro-6-fluorophenyl)prop-1-enyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C27H22ClF4NO5S
 1
1
EC50 = 324 nM
   TI
   LI
   LO
   TS
CP0138639
3-[(2S)-6-[(E)-2-(2-methoxyphenyl)prop-1-enyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C28H26F3NO6S
 1
1
EC50 = 328 nM
   TI
   LI
   LO
   TS
CP0471273
3-[(2S)-6-(2,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]-2,2-dimethylpropanoic acid
   Show/Hide
C26H22F5NO5S
 1
1
EC50 = 344 nM
   TI
   LI
   LO
   TS
CP0138557
3-[(2S)-6-[(E)-2-(2-chloro-6-fluorophenyl)prop-1-enyl]-4-[[2-(2-hydroxyethoxy)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl]sulfonyl]-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C29H31ClFN3O7S
 1
1
EC50 = 381 nM
   TI
   LI
   LO
   TS
CP0168528
4-[4-[[benzylsulfonyl(2-methylpropyl)amino]methyl]phenyl]benzamide
   Show/Hide
C25H28N2O3S
 1
1
EC50 = 400 nM
   TI
   LI
   LO
   TS
CP0539745
3-[(2S)-6-(3-fluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C24H19F4NO5S
 1
1
EC50 = 408 nM
   TI
   LI
   LO
   TS
CP0550332
3-[(2S)-6-[(E)-2-(2-chloro-6-fluorophenyl)prop-1-enyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C27H21ClF5NO5S
 1
1
EC50 = 411 nM
   TI
   LI
   LO
   TS
CP0552384
3-[(2S)-6-(2-chlorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C24H19ClF3NO5S
 1
1
EC50 = 414 nM
   TI
   LI
   LO
   TS
CP0257822
N-(2-methylpropyl)-N-[[4-(4-methylsulfonylphenyl)phenyl]methyl]-1-phenylmethanesulfonamide
   Show/Hide
C25H29NO4S2
 1
1
EC50 = 450 nM
   TI
   LI
   LO
   TS
CP0059785
N-[[4-[4-(methanesulfonamido)phenyl]phenyl]methyl]-N-(2-methylpropyl)-1-phenylmethanesulfonamide
   Show/Hide
C25H30N2O4S2
 1
1
EC50 = 470 nM
   TI
   LI
   LO
   TS
CP0527541
3-[(2S)-6-[(E)-2-(2,6-dichlorophenyl)prop-1-enyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C27H22Cl2F3NO5S
 1
1
EC50 = 487 nM
   TI
   LI
   LO
   TS
CP0557795
(2S)-3-[(2S)-6-(2,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]-2-methylpropanoic acid
   Show/Hide
C25H20F5NO5S
 1
1
EC50 = 489 nM
   TI
   LI
   LO
   TS
CP0552371
3-[(2S)-6-[(E)-2-(2-chloro-6-fluorophenyl)prop-1-enyl]-4-(3-cyclopropyl-4-fluorophenyl)sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C29H26ClF2NO5S
 1
1
EC50 = 495 nM
   TI
   LI
   LO
   TS
CP0471264
(2S)-4-[(2S)-6-(2,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]-2-hydroxybutanoic acid
   Show/Hide
C25H20F5NO6S
 1
1
EC50 = 501 nM
   TI
   LI
   LO
   TS
CP0487452
3-[(2S)-6-[(E)-2-(2-chloro-6-fluorophenyl)prop-1-enyl]-4-(4-fluoro-3-methoxyphenyl)sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C27H24ClF2NO6S
 1
1
EC50 = 520 nM
   TI
   LI
   LO
   TS
CP0550333
3-[(2S)-6-[(E)-2-(2-chloro-6-fluorophenyl)ethenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C26H20ClF4NO5S
 1
1
EC50 = 617 nM
   TI
   LI
   LO
   TS
CP0534360
3-[(2S)-6-[(E)-2-phenylprop-1-enyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C27H24F3NO5S
 1
1
EC50 = 631 nM
   TI
   LI
   LO
   TS
CP0234135
N-(2-methylpropyl)-N-[[5-(4-methylsulfonylphenyl)thiophen-2-yl]methyl]-1-phenylmethanesulfonamide
   Show/Hide
C23H27NO4S3
 1
1
EC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0562991
[3-[[(2S)-6-bromo-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]methyl]oxetan-3-yl]methanol
   Show/Hide
C20H19BrF3NO5S
 1
1
EC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0059780
N-(2-methylpropyl)-N-[[5-(3-methylsulfonylphenyl)thiophen-2-yl]methyl]-1-phenylmethanesulfonamide
   Show/Hide
C23H27NO4S3
 1
1
EC50 = 2400 nM
   TI
   LI
   LO
   TS
CP0189594
3-[(2S)-6-[(E)-2-(2-chlorophenyl)prop-1-enyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C27H23ClF3NO5S
 1
1
EC50 = 2740 nM
   TI
   LI
   LO
   TS
CP0205289
N-[5-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]sulfamoyl]-4-methyl-1,3-thiazol-2-yl]acetamide
   Show/Hide
C15H13F6N3O4S2
 1
1
EC50 = 4000 nM
   TI
   LI
   LO
   TS
CP0138638
3-[(2S)-6-(4-propan-2-ylphenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C27H26F3NO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0527539
4-[[(2S)-6-(2,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]methyl]oxane-4-carboxylic acid
   Show/Hide
C28H24F5NO6S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0546382
3-[(2S)-6-[(E)-2-(4-methylphenyl)ethenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C27H24F3NO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0546458
3-[(2S)-6-[3-(2-hydroxyethoxy)phenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C26H24F3NO7S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0546643
3-[(2S)-6-[(E)-2-(4-chloro-2-fluorophenyl)ethenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
   Show/Hide
C26H20ClF4NO5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0411472
2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]-N-(2-fluorophenyl)-2-methylpropanamide
   Show/Hide
C26H27FN2O4S
 1
1
IC50 = 4.4 nM
   TI
   LI
   LO
   TS
CP0489514
N-(4-chloropyridin-2-yl)-2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]-2-methylpropanamide
   Show/Hide
C25H26ClN3O4S
 1
1
IC50 = 8.2 nM
   TI
   LI
   LO
   TS
CP0411477
2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]-N-(3-fluorophenyl)-2-methylpropanamide
   Show/Hide
C26H27FN2O4S
 1
1
IC50 = 9.8 nM
   TI
   LI
   LO
   TS
CP0262112
N-[4-[1-(2,3-dihydroindol-1-yl)-2-methyl-1-oxopropan-2-yl]phenyl]-2-(4-ethylsulfonylphenyl)acetamide
   Show/Hide
C28H30N2O4S
 1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
CP0168881
2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]-2-methyl-N-phenylpropanamide
   Show/Hide
C26H28N2O4S
 1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
CP0262111
2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]-N,2-dimethyl-N-phenylpropanamide
   Show/Hide
C27H30N2O4S
 1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
CP0116135
N-(4-cyanopyridin-2-yl)-2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]-2-fluorophenyl]-2-methylpropanamide
   Show/Hide
C26H25FN4O4S
 1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
CP0262113
2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]-2-fluorophenyl]-N-(4-fluorophenyl)-2-methylpropanamide
   Show/Hide
C26H26F2N2O4S
 1
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
CP0440462
2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]-2-methyl-N-[4-(trifluoromethyl)pyridin-2-yl]propanamide
   Show/Hide
C26H26F3N3O4S
 1
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
CP0116165
N-(2,4-difluorophenyl)-2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]-2-fluorophenyl]-2-methylpropanamide
   Show/Hide
C26H25F3N2O4S
 1
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
CP0411468
2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]-N-(4-fluoropyridin-2-yl)-2-methylpropanamide
   Show/Hide
C25H26FN3O4S
 1
1
IC50 = 31 nM
   TI
   LI
   LO
   TS
CP0116134
2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]-N-(4-fluorophenyl)-2-methylpropanamide
   Show/Hide
C26H27FN2O4S
 1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS
CP0392911
2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]-2-methyl-N-pyridin-2-ylpropanamide
   Show/Hide
C25H27N3O4S
 1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
CP0407819
N-(4-cyanopyridin-2-yl)-2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]-2-methylpropanamide
   Show/Hide
C26H26N4O4S
 1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
CP0577410
US9598415, 201
   Show/Hide
C28H32N8O3S
 1
1
IC50 = 74 nM
   TI
   LI
   LO
   TS
CP0566256
US9598415, 158
   Show/Hide
C27H30N8O3S
 1
1
IC50 = 90 nM
   TI
   LI
   LO
   TS
CP0440463
N-(2,4-difluorophenyl)-2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]-2-methylpropanamide
   Show/Hide
C26H26F2N2O4S
 1
1
IC50 = 95 nM
   TI
   LI
   LO
   TS
CP0490584
US9598415, 138
   Show/Hide
C27H36N8O3S
 1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
CP0553078
US9598415, 113
   Show/Hide
C27H27F3N8O4S
 1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
CP0485005
US9598415, 17
   Show/Hide
C26H30N8O4S
 1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
CP0411464
2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]-2-methyl-N-(2-methylphenyl)propanamide
   Show/Hide
C27H30N2O4S
 1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
CP0440464
2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]-2-methyl-N-pyridin-3-ylpropanamide
   Show/Hide
C25H27N3O4S
 1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
CP0423733
US9598415, 136
   Show/Hide
C26H28N8O3S
 1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
CP0558782
US9598415, 128
   Show/Hide
C26H28N8O3S
 1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
CP0243406
N-[4-[1-(azetidin-1-yl)-2-methyl-1-oxopropan-2-yl]phenyl]-2-(4-ethylsulfonylphenyl)acetamide
   Show/Hide
C23H28N2O4S
 1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS
CP0566255
8-[(1S)-1-cyclopropylethyl]-2-(4-cyclopropyl-6-methylpyrimidin-5-yl)-6-[(5-methylsulfonylpyrazin-2-yl)methylamino]pteridin-7-one
   Show/Hide
C25H27N9O3S
 1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS
CP0479578
US9598415, 69
   Show/Hide
C27H30N8O3S
 1
1
IC50 = 190 nM
   TI
   LI
   LO
   TS
CP0553077
US9598415, 9
   Show/Hide
C25H28N8O4S
 1
1
IC50 = 190 nM
   TI
   LI
   LO
   TS
CP0558868
US9598415, 214
   Show/Hide
C25H27N9O3S
 1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
CP0540108
US9598415, 8
   Show/Hide
C26H30N8O4S
 1
1
IC50 = 230 nM
   TI
   LI
   LO
   TS
CP0571442
US9598415, 170
   Show/Hide
C27H32N8O4S
 1
1
IC50 = 230 nM
   TI
   LI
   LO
   TS
CP0361258
N-[4-[1-(1,3-dihydroisoindol-2-yl)-2-methyl-1-oxopropan-2-yl]phenyl]-2-(4-ethylsulfonylphenyl)acetamide
   Show/Hide
C28H30N2O4S
 1
1
IC50 = 260 nM
   TI
   LI
   LO
   TS
CP0552040
US9598415, 137
   Show/Hide
C27H29N7O3S
 1
1
IC50 = 260 nM
   TI
   LI
   LO
   TS
CP0552579
6-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-2-[(5-ethylsulfonylpyridin-2-yl)methylamino]-4-propan-2-ylpyrido[2,3-b]pyrazin-3-one
   Show/Hide
C26H29N7O4S
 1
1
IC50 = 260 nM
   TI
   LI
   LO
   TS
CP0537560
US9598415, 70
   Show/Hide
C26H29N9O3S
 1
1
IC50 = 270 nM
   TI
   LI
   LO
   TS
CP0558861
US9598415, 142
   Show/Hide
C25H29N9O3S
 1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS
CP0558858
US9598415, 253
   Show/Hide
C26H30N8O4S
 1
1
IC50 = 290 nM
   TI
   LI
   LO
   TS
CP0528374
US9598415, 11
   Show/Hide
C25H28N8O3S
 1
1
IC50 = 300 nM
   TI
   LI
   LO
   TS
CP0396018
2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]-N-(3-fluoropyridin-2-yl)-2-methylpropanamide
   Show/Hide
C25H26FN3O4S
 1
1
IC50 = 310 nM
   TI
   LI
   LO
   TS
CP0495610
US9598415, 15
   Show/Hide
C27H30N8O3S
 1
1
IC50 = 310 nM
   TI
   LI
   LO
   TS
CP0553079
US9598415, 12
   Show/Hide
C27H32N8O4S
 1
1
IC50 = 310 nM
   TI
   LI
   LO
   TS
CP0490585
US9598415, 103
   Show/Hide
C25H28N8O3S2
 1
1
IC50 = 320 nM
   TI
   LI
   LO
   TS
CP0479580
US9598415, 68
   Show/Hide
C27H30N8O4S
 1
1
IC50 = 330 nM
   TI
   LI
   LO
   TS
CP0558866
7-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-3-[(5-ethylsulfonylpyridin-2-yl)methylamino]-1-propan-2-ylquinoxalin-2-one
   Show/Hide
C27H30N6O4S
 1
1
IC50 = 350 nM
   TI
   LI
   LO
   TS
CP0484643
US9598415, 22
   Show/Hide
C27H32N8O4S
 1
1
IC50 = 360 nM
   TI
   LI
   LO
   TS
CP0560908
US9598415, 21
   Show/Hide
C26H30N8O3S
 1
1
IC50 = 360 nM
   TI
   LI
   LO
   TS
CP0407763
2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]-N,N,2-trimethylpropanamide
   Show/Hide
C22H28N2O4S
 1
1
IC50 = 370 nM
   TI
   LI
   LO
   TS
CP0558869
8-[(1S)-1-cyclopropylethyl]-2-(4-cyclopropyl-6-methylpyrimidin-5-yl)-6-[(2-ethylsulfonylspiro[3.3]heptan-6-yl)methylamino]pteridin-7-one
   Show/Hide
C29H37N7O3S
 1
1
IC50 = 370 nM
   TI
   LI
   LO
   TS
CP0555726
6-[[[8-[(1S)-1-cyclopropylethyl]-2-(4-cyclopropyl-6-methylpyrimidin-5-yl)-7-oxopteridin-6-yl]amino]methyl]-N-methylpyridine-3-sulfonamide
   Show/Hide
C26H29N9O3S
 1
1
IC50 = 380 nM
   TI
   LI
   LO
   TS
CP0552577
US9598415, 24
   Show/Hide
C27H32N8O4S
 1
1
IC50 = 390 nM
   TI
   LI
   LO
   TS
CP0116164
ethyl 2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]-2-methylpropanoate
   Show/Hide
C22H27NO5S
 1
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
CP0423455
US9598415, 74
   Show/Hide
C27H30N8O4S
 1
1
IC50 = 410 nM
   TI
   LI
   LO
   TS
CP0552580
5-(4-hydroxy-2-methylphenyl)-N-[[4-(methylsulfamoyl)phenyl]methyl]spiro[2H-pyrrolo[3,2-b]pyridine-3,1'-cyclopentane]-1-carboxamide
   Show/Hide
C27H30N4O4S
 1
1
IC50 = 410 nM
   TI
   LI
   LO
   TS
CP0495609
US9598415, 52
   Show/Hide
C26H28N8O4S
 1
1
IC50 = 420 nM
   TI
   LI
   LO
   TS
CP0085610
2-(4-ethylsulfonylphenyl)-N-[4-(2-methyl-1-oxo-1-piperidin-1-ylpropan-2-yl)phenyl]acetamide
   Show/Hide
C25H32N2O4S
 1
1
IC50 = 430 nM
   TI
   LI
   LO
   TS
CP0560909
US9598415, 146
   Show/Hide
C24H28N8O3S
 1
1
IC50 = 440 nM
   TI
   LI
   LO
   TS
CP0361257
N-[4-[1-(2-azaspiro[3.3]heptan-2-yl)-2-methyl-1-oxopropan-2-yl]phenyl]-2-(4-ethylsulfonylphenyl)acetamide
   Show/Hide
C26H32N2O4S
 1
1
IC50 = 470 nM
   TI
   LI
   LO
   TS
CP0485006
US9598415, 61
   Show/Hide
C25H25F3N8O4S
 1
1
IC50 = 470 nM
   TI
   LI
   LO
   TS
CP0553080
6-[(5-ethylsulfonylpyridin-2-yl)methylamino]-2-(6-methoxyquinolin-5-yl)-8-propan-2-ylpteridin-7-one
   Show/Hide
C27H27N7O4S
 1
1
IC50 = 480 nM
   TI
   LI
   LO
   TS
CP0536883
2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]-2-methyl-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
   Show/Hide
C26H26F3N3O4S
 1
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
CP0552110
US9598415, 249
   Show/Hide
C28H30N8O3S
 1
1
IC50 = 520 nM
   TI
   LI
   LO
   TS
CP0528375
8-[(1S)-1-cyclopropylethyl]-2-(4-cyclopropyl-6-methylpyrimidin-5-yl)-6-[[5-(methylsulfonimidoyl)pyridin-2-yl]methylamino]pteridin-7-one
   Show/Hide
C26H29N9O2S
 1
1
IC50 = 540 nM
   TI
   LI
   LO
   TS
CP0556065
8-tert-butyl-2-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-6-[(5-ethylsulfonylpyridin-2-yl)methylamino]pteridin-7-one
   Show/Hide
C26H30N8O4S
 1
1
IC50 = 670 nM
   TI
   LI
   LO
   TS
CP0558867
US9598415, 204
   Show/Hide
C27H28N8O2
 1
1
IC50 = 670 nM
   TI
   LI
   LO
   TS
CP0459436
5-butyl-9-chloro-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenanthridin-6-one
   Show/Hide
C20H16ClF6NO2
 1
1
IC50 = 690 nM
   TI
   LI
   LO
   TS
CP0540107
US9598415, 34
   Show/Hide
C26H30N8O5S
 1
1
IC50 = 740 nM
   TI
   LI
   LO
   TS
CP0553081
US9598415, 141
   Show/Hide
C23H26N8O5S
 1
1
IC50 = 800 nM
   TI
   LI
   LO
   TS
CP0487873
5-butyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-9-methylphenanthridin-6-one
   Show/Hide
C21H19F6NO2
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0488049
5-butyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-9-methoxyphenanthridin-6-one
   Show/Hide
C21H19F6NO3
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0248164
1-[4-[[3-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,2-dioxo-2lambda6,1,3-benzothiadiazol-1-yl]methyl]piperidin-1-yl]-2-methylpropan-1-one
   Show/Hide
C26H29F6N3O4S
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0560910
6-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-2-[(5-ethylsulfonylpyridin-2-yl)methylamino]-4-propan-2-ylpyrazino[2,3-b]pyrazin-3-one
   Show/Hide
C25H28N8O4S
 1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0141496
1-[3-[[3-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,2-dioxo-2lambda6,1,3-benzothiadiazol-1-yl]methyl]piperidin-1-yl]propan-1-one
   Show/Hide
C25H27F6N3O4S
 1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS
CP0558865
7-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-3-[(5-ethylsulfonylpyridin-2-yl)methylamino]-1-propan-2-ylpyrido[3,4-b]pyrazin-2-one
   Show/Hide
C26H29N7O4S
 1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS
CP0565059
1-(4-fluorophenyl)-7-methoxy-N-[[4-(methylsulfamoyl)phenyl]methyl]pyrazolo[3,4-c]pyridine-4-carboxamide
   Show/Hide
C22H20FN5O4S
 1
1
IC50 = 1600 nM
   TI
   LI
   LO
   TS
CP0411475
2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]-2-methyl-N-pyridin-4-ylpropanamide
   Show/Hide
C25H27N3O4S
 1
1
IC50 = 1800 nM
   TI
   LI
   LO
   TS
CP0335474
4-[3-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,2-dioxo-2lambda6,1,3-benzothiadiazol-1-yl]-1-pyrrolidin-1-ylbutan-1-one
   Show/Hide
C24H25F6N3O4S
 1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0558860
2-(3-cyclopropylpyrazin-2-yl)-6-[(5-ethylsulfonylpyridin-2-yl)methylamino]-8-propan-2-ylpteridin-7-one
   Show/Hide
C24H26N8O3S
 1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
CP0247502
4-[3-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,2-dioxo-2lambda6,1,3-benzothiadiazol-1-yl]-N-methyl-N-[(2-methylphenyl)methyl]butanamide
   Show/Hide
C29H29F6N3O4S
 1
1
IC50 = 2200 nM
   TI
   LI
   LO
   TS
CP0459435
5-butyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-9-(trifluoromethyl)phenanthridin-6-one
   Show/Hide
C21H16F9NO2
 1
1
IC50 = 2600 nM
   TI
   LI
   LO
   TS
CP0558859
6-[(5-ethylsulfonylpyridin-2-yl)methylamino]-2-(4-fluoro-2-methylphenyl)-8-propan-2-ylpteridin-7-one
   Show/Hide
C24H25FN6O3S
 1
1
IC50 = 2800 nM
   TI
   LI
   LO
   TS
CP0528373
2-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-6-[(5-ethylsulfonylpyridin-2-yl)methylamino]-8-propylpteridin-7-one
   Show/Hide
C25H28N8O4S
 1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0260030
4-[2,2-dioxo-3-[(4-pentan-3-ylphenyl)methyl]-2lambda6,1,3-benzothiadiazol-1-yl]-1-pyrrolidin-1-ylbutan-1-one
   Show/Hide
C26H35N3O3S
 1
1
IC50 = 3400 nM
   TI
   LI
   LO
   TS
CP0484642
2-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-6-[(5-ethylsulfonylpyridin-2-yl)methylamino]-8-phenylpteridin-7-one
   Show/Hide
C28H26N8O4S
 1
1
IC50 = 3800 nM
   TI
   LI
   LO
   TS
CP0380839
5-butyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenanthridin-6-one
   Show/Hide
C20H17F6NO2
 2
1
IC50 = 3900 nM
   TI
   LI
   LO
   TS
2
IC50 = 4700 nM
   TI
   LI
   LO
   TS
CP0524496
5-butyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-9-hydroxyphenanthridin-6-one
   Show/Hide
C20H17F6NO3
 1
1
IC50 = 4100 nM
   TI
   LI
   LO
   TS
CP0334820
4-[3-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,2-dioxo-2lambda6,1,3-benzothiadiazol-1-yl]-N-[(3-methoxyphenyl)methyl]-N-methylbutanamide
   Show/Hide
C29H29F6N3O5S
 1
1
IC50 = 4100 nM
   TI
   LI
   LO
   TS
CP0484644
7-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-3-[(5-ethylsulfonylpyridin-2-yl)methylamino]-1-propan-2-ylpyrido[2,3-b]pyrazin-2-one
   Show/Hide
C26H29N7O4S
 1
1
IC50 = 4100 nM
   TI
   LI
   LO
   TS
CP0395440
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-5-propylphenanthridin-6-one
   Show/Hide
C19H15F6NO2
 1
1
IC50 = 4200 nM
   TI
   LI
   LO
   TS
CP0381823
2-(5,5-diethylbenzo[b][1]benzosilol-2-yl)-1,1,1,3,3,3-hexafluoropropan-2-ol
   Show/Hide
C19H18F6OSi
 1
1
IC50 = 4200 nM
   TI
   LI
   LO
   TS
CP0456138
2-(5-butyl-5-methylbenzo[b][1]benzosilol-2-yl)-1,1,1,3,3,3-hexafluoropropan-2-ol
   Show/Hide
C20H20F6OSi
 1
1
IC50 = 4400 nM
   TI
   LI
   LO
   TS
CP0003740
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide
   Show/Hide
C17H12F9NO3S
 2
1
IC50 = 4400 nM
   TI
   LI
   LO
   TS
2
IC50 = 6500 nM
   TI
   LI
   LO
   TS
CP0481996
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-5-hexylphenanthridin-6-one
   Show/Hide
C22H21F6NO2
 1
1
IC50 = 4700 nM
   TI
   LI
   LO
   TS
CP0401199
2-(5,5-dimethylbenzo[b][1]benzosilol-2-yl)-1,1,1,3,3,3-hexafluoropropan-2-ol
   Show/Hide
C17H14F6OSi
 1
1
IC50 = 5400 nM
   TI
   LI
   LO
   TS
CP0389304
2-(5,5-dibutylbenzo[b][1]benzosilol-2-yl)-1,1,1,3,3,3-hexafluoropropan-2-ol
   Show/Hide
C23H26F6OSi
 1
1
IC50 = 5500 nM
   TI
   LI
   LO
   TS
CP0089428
4-[2,2-dioxo-3-[(4-propan-2-ylphenyl)methyl]-2lambda6,1,3-benzothiadiazol-1-yl]-1-pyrrolidin-1-ylbutan-1-one
   Show/Hide
C24H31N3O3S
 1
1
IC50 = 5600 nM
   TI
   LI
   LO
   TS
CP0473976
5-butyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-10-methoxyphenanthridin-6-one
   Show/Hide
C21H19F6NO3
 1
1
IC50 = 5700 nM
   TI
   LI
   LO
   TS
CP0129839
4-[3-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,2-dioxo-2lambda6,1,3-benzothiadiazol-1-yl]-N-(4-hydroxybutan-2-yl)-N-methylbutanamide
   Show/Hide
C25H29F6N3O5S
 1
1
IC50 = 5700 nM
   TI
   LI
   LO
   TS
CP0552578
5-[(1S)-1-cyclopropylethyl]-3-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-7-[(5-ethylsulfonylpyridin-2-yl)methylamino]pyrazino[2,3-c]pyridazin-6-one
   Show/Hide
C27H30N8O4S
 1
1
IC50 = 5700 nM
   TI
   LI
   LO
   TS
CP0488050
5-(cyclohexylmethyl)-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenanthridin-6-one
   Show/Hide
C23H21F6NO2
 1
1
IC50 = 5800 nM
   TI
   LI
   LO
   TS
CP0467808
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-5-propan-2-ylphenanthridin-6-one
   Show/Hide
C19H15F6NO2
 1
1
IC50 = 6000 nM
   TI
   LI
   LO
   TS
CP0499213
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-5-(2,2,2-trifluoroethyl)phenanthridin-6-one
   Show/Hide
C18H10F9NO2
 1
1
IC50 = 9000 nM
   TI
   LI
   LO
   TS
CP0380838
5-butyl-2-ethylphenanthridin-6-one
   Show/Hide
C19H21NO
 1
1
IC50 = 9200 nM
   TI
   LI
   LO
   TS
CP0395912
5-butyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-3-methoxyphenanthridin-6-one
   Show/Hide
C21H19F6NO3
 1
1
IC50 = 9200 nM
   TI
   LI
   LO
   TS
CP0459432
5-(cyclopropylmethyl)-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenanthridin-6-one
   Show/Hide
C20H15F6NO2
 1
1
IC50 = 9300 nM
   TI
   LI
   LO
   TS
CP0467810
5-butyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4-methoxyphenanthridin-6-one
   Show/Hide
C21H19F6NO3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0487874
5-butyl-2-tert-butylphenanthridin-6-one
   Show/Hide
C21H25NO
 1
1
IC50 = 10400 nM
   TI
   LI
   LO
   TS
CP0385671
N-[4-[hydroxy(dimethyl)silyl]phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide
   Show/Hide
C16H18F3NO3SSi
 1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS
CP0467809
5-butyl-2-propan-2-ylphenanthridin-6-one
   Show/Hide
C20H23NO
 1
1
IC50 = 11900 nM
   TI
   LI
   LO
   TS
CP0459431
5-butyl-2-hexylphenanthridin-6-one
   Show/Hide
C23H29NO
 1
1
IC50 = 13000 nM
   TI
   LI
   LO
   TS
CP0553082
1-butan-2-yl-7-[cyclohexyl(methyl)amino]-3-(4-methylpiperazin-1-yl)pyrido[3,4-b]pyrazin-2-one
   Show/Hide
C23H36N6O
 1
1
IC50 = 13000 nM
   TI
   LI
   LO
   TS
CP0417384
5-butylphenanthridin-6-one
   Show/Hide
C17H17NO
 1
1
IC50 = 14500 nM
   TI
   LI
   LO
   TS
CP0334821
4-[2,2-dioxo-3-[[4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl]methyl]-2lambda6,1,3-benzothiadiazol-1-yl]-1-pyrrolidin-1-ylbutan-1-one
   Show/Hide
C23H26F3N3O4S
 1
1
IC50 = 16000 nM
   TI
   LI
   LO
   TS
CP0459433
5-butyl-2-methylphenanthridin-6-one
   Show/Hide
C18H19NO
 1
1
IC50 = 16800 nM
   TI
   LI
   LO
   TS
CP0577430
2-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-6-[(5-ethylsulfonylpyridin-2-yl)methylamino]-8-(2-hydroxypropan-2-yl)pteridin-7-one
   Show/Hide
C25H28N8O5S
 1
1
IC50 = 17000 nM
   TI
   LI
   LO
   TS
CP0152535
4-(3-benzyl-2,2-dioxo-2lambda6,1,3-benzothiadiazol-1-yl)-1-pyrrolidin-1-ylbutan-1-one
   Show/Hide
C21H25N3O3S
 1
1
IC50 = 18000 nM
   TI
   LI
   LO
   TS
CP0395918
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-5-nonylphenanthridin-6-one
   Show/Hide
C25H27F6NO2
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0395919
5-ethyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenanthridin-6-one
   Show/Hide
C18H13F6NO2
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0397540
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-5-methylphenanthridin-6-one
   Show/Hide
C17H11F6NO2
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0459434
5-butyl-2-(hydroxymethyl)phenanthridin-6-one
   Show/Hide
C18H19NO2
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0478004
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-5H-phenanthridin-6-one
   Show/Hide
C16H9F6NO2
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0394583
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4-methyl-5H-phenanthridin-6-one
   Show/Hide
C17H11F6NO2
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0390984
N-butyl-N-[4-[hydroxy(dimethyl)silyl]phenyl]benzenesulfonamide
   Show/Hide
C18H25NO3SSi
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0396597
N-[4-(2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide
   Show/Hide
C17H18F3NO3S
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0396599
N-[4-[hydroxy(dimethyl)silyl]phenyl]-N-(2-phenylethyl)benzenesulfonamide
   Show/Hide
C22H25NO3SSi
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0396600
N-benzyl-N-[4-[hydroxy(dimethyl)silyl]phenyl]benzenesulfonamide
   Show/Hide
C21H23NO3SSi
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0466299
N-ethyl-N-[4-[hydroxy(dimethyl)silyl]phenyl]benzenesulfonamide
   Show/Hide
C16H21NO3SSi
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0555785
methyl 2-[N-(benzenesulfonyl)-4-(2-hydroxypropan-2-yl)anilino]acetate
   Show/Hide
C18H21NO5S
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0558863
2-(4-cyclopropyl-6-oxo-1H-pyrimidin-5-yl)-6-[(5-ethylsulfonylpyridin-2-yl)methylamino]-8-propan-2-ylpteridin-7-one
   Show/Hide
C24H26N8O4S
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0558864
6-[(5-ethylsulfonylpyridin-2-yl)methylamino]-8-propan-2-yl-2-pyrimidin-5-ylpteridin-7-one
   Show/Hide
C21H22N8O3S
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS