Brief Information of the Compound and Protein
Compound Name
2-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-6-[(5-ethylsulfonylpyridin-2-yl)methylamino]-8-(2-hydroxypropan-2-yl)pteridin-7-one
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Canonical SMILES
CCS(=O)(=O)c1ccc(CNc2nc3cnc(nc3n(c2=O)C(C)(C)O)-c2c(OC)ncnc2C2CC2)nc1
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Compound Formula C25H28N8O5S
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 17000 nM
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