Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-butan-2-yl-7-[cyclohexyl(methyl)amino]-3-(4-methylpiperazin-1-yl)pyrido[3,4-b]pyrazin-2-one
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Canonical SMILES
CCC(C)n1c2cc(ncc2nc(N2CCN(C)CC2)c1=O)N(C)C1CCCCC1
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Compound Formula C23H36N6O
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 13000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 780 nM