Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[3-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,2-dioxo-2lambda6,1,3-benzothiadiazol-1-yl]-N-(4-hydroxybutan-2-yl)-N-methylbutanamide
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 PubChem ID
CID: 118728935
Canonical SMILES
CC(CCO)N(C)C(=O)CCCN1c2ccccc2N(Cc2ccc(cc2)C(O)(C(F)(F)F)C(F)(F)F)S1(=O)=O
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Compound Formula C25H29F6N3O5S
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 5700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5400 nM
2 Kd = 1600 nM