Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[3-[[3-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,2-dioxo-2lambda6,1,3-benzothiadiazol-1-yl]methyl]piperidin-1-yl]propan-1-one
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 PubChem ID
CID: 118728940
Canonical SMILES
CCC(=O)N1CCCC(CN2c3ccccc3N(Cc3ccc(cc3)C(O)(C(F)(F)F)C(F)(F)F)S2(=O)=O)C1
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Compound Formula C25H27F6N3O4S
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 440 nM
2 Kd = 450 nM