Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[[(2S)-6-(3-chloro-2-fluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]methyl]oxane-4-carboxylic acid
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 PubChem ID
CID: 124133317
Canonical SMILES
OC(=O)C1(C[C@H]2CN(c3cc(ccc3O2)-c2cccc(Cl)c2F)S(=O)(=O)c2cccc(c2)C(F)(F)F)CCOCC1
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Compound Formula C28H24ClF4NO6S
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 103 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
EC50 = 24 nM
   TI
   LI
   LO
   TS