Brief Information of the Compound and Protein
Compound Name
4-(3-benzyl-2,2-dioxo-2lambda6,1,3-benzothiadiazol-1-yl)-1-pyrrolidin-1-ylbutan-1-one
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PubChem ID
CID: 118728944
Canonical SMILES
O=C(CCCN1c2ccccc2N(Cc2ccccc2)S1(=O)=O)N1CCCC1
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Compound Formula C21H25N3O3S
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 18000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 2700 nM