Brief Information of the Compound and Protein
Compound Name
7-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-3-[(5-ethylsulfonylpyridin-2-yl)methylamino]-1-propan-2-ylquinoxalin-2-one
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Canonical SMILES
CCS(=O)(=O)c1ccc(CNc2nc3ccc(cc3n(C(C)C)c2=O)-c2c(OC)ncnc2C2CC2)nc1
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Compound Formula C27H30N6O4S
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 350 nM
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