| Compound ID |
Compound Name |
Compound Formula |
|
CP0372168
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Ac-Nle-c[Asp-trans-4-guanidinyl-Pro-DNal(2')-Arg-Trp-Lys]-NH2
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C54H74N16O9
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2
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| 1 |
EC50 = 0.3 nM
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| 2 |
IC50 = 0.7 nM
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CP0041451
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CAS_75921-69-6
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C78H111N21O19
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5
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| 1 |
EC50 = 0.4 nM
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|
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| 2 |
EC50 = 1 nM
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| 3 |
EC50 = 1.1 nM
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| 4 |
IC50 = 2.2 nM
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| 5 |
Ki = 9.9 nM
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CP0382074
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,7,13-tetramethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C58H79N15O9
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2
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| 1 |
EC50 = 0.8 nM
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|
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| 2 |
IC50 = 8.1 nM
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CP0390481
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(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]-5-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-2-oxoethyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]pentanoic acid
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C78H113N21O18
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2
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| 1 |
EC50 = 1 nM
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|
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| 2 |
IC50 = 2.2 nM
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CP0149707
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8-(3-Guanidino-propyl)-2-(3H-imidazol-4-ylmethyl)-11-(1H-indol-3-ylmethyl)-5-naphthalen-2-ylmethyl-3,6,9,12,20,24-hexaoxo-1,4,7,10,13,19hexaaza-cyclotetracosane-14-carboxylic acid amide
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C47H59N13O7
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2
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| 1 |
EC50 = 1.01 nM
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|
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| 2 |
Ki = 26 nM
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CP0376221
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C57H77N15O9
|
3
|
| 1 |
EC50 = 1.1 nM
|
|
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| 2 |
IC50 = 268 nM
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|
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| 3 |
Kd = 39.81 nM
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CP0050965
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21-(2-Acetylamino-hexanoylamino)-7-[3-(diaminomethaniminium)-propyl]-10-(1H-indol-3-ylmethyl)-4-naphthalen-2-ylmethyl-2,5,8,11,19,22-hexaoxo-3,6,9,12,18,23-hexaaza-tricyclo[21.7.0.0*24,29*]triaconta-24(29),25,27
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C54H71N15O9
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2
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| 1 |
EC50 = 1.2 nM
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| 2 |
IC50 = 0.9 nM
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CP0375705
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Ac-Nle-c[Asp-trans-4-guanidinyl-Pro-DPhe-Arg-Trp-Lys]-NH2
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C50H72N16O9
|
2
|
| 1 |
EC50 = 1.6 nM
|
|
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| 2 |
IC50 = 2.5 nM
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CP0091326
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(3S,6S,9R,12S,15S,23S)-15-((S)-2-acetylamino-hexanoylamino)-9-benzyl-6-(3-guanidino-propyl)-12-(3H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotricosane-23-carboxylic acid amide
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|
C50H69N15O9
|
13
|
| 1 |
EC50 = 1.7 nM
|
|
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| 2 |
EC50 = 3.3 nM
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|
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| 3 |
EC50 = 5.7 nM
|
|
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| 4 |
EC50 = 6 nM
|
|
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| 5 |
EC50 = 8 nM
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|
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| 6 |
EC50 = 33.9 nM
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| 7 |
IC50 = 1.5 nM
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| 8 |
IC50 = 4 nM
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| 9 |
IC50 = 4.2 nM
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| 10 |
IC50 = 7 nM
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|
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| 11 |
IC50 = 7.47 nM
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| 12 |
IC50 = 7.5 nM
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|
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| 13 |
IC50 = 23.44 nM
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CP0388054
|
Ac-Tyr-Val-Nle-Gly-His-DPhe-Arg-Trp-Asp-Arg-Phe-Gly-NH2)
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|
C77H104N22O16
|
2
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| 1 |
EC50 = 1.9 nM
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| 2 |
IC50 = 2.4 nM
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CP0393265
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Ac-Tyr-Val-Nle-Gly-His-D-Phe-Arg-Trp-Asp-Arg-Phe-Gly-NH2
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C77H104N22O17
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2
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| 1 |
EC50 = 1.9 nM
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| 2 |
IC50 = 2.4 nM
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CP0402650
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(11S,14S,17S,20R,23S)-20-benzyl-17-[3-(diaminomethylideneamino)propyl]-23-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-8,13,16,19,22,25-hexaoxo-7,12,15,18,21,24-hexazaspiro[5.19]pentacosane-11-carboxamide
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C44H57N13O7
|
2
|
| 1 |
EC50 = 1.9 nM
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|
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| 2 |
IC50 = 630 nM
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CP0404108
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(9S,12S,15S,18R,21S)-18-benzyl-15-[3-(diaminomethylideneamino)propyl]-21-(1H-imidazol-5-ylmethyl)-12-(1H-indol-3-ylmethyl)-6,11,14,17,20,23-hexaoxo-5,10,13,16,19,22-hexazaspiro[3.19]tricosane-9-carboxamide
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|
C42H53N13O7
|
2
|
| 1 |
EC50 = 2 nM
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| 2 |
IC50 = 380 nM
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CP0762853
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15-(2-Acetylamino-hexanoylamino)-9-benzyl-6-(3-guanidino-propyl)-12-(3H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotetracosane-24-carboxylic acid amide
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|
C51H71N15O9
|
2
|
| 1 |
EC50 = 3.3 nM
|
|
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| 2 |
Ki = 6.96 nM
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CP0462964
|
(3S,6S,9R,12S,15S,23S)-15-[(2S)-2-aminohexanamido]-6-(3-carbamimidamidopropyl)-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-23-carboxamide
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|
C52H69N15O8
|
2
|
| 1 |
EC50 = 3.3 nM
|
|
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| 2 |
IC50 = 7.47 nM
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CP0045745
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(S)-2-{(R)-2-[(S)-2-Acetylamino-3-(1H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
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C34H43N11O5
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2
|
| 1 |
EC50 = 3.9 nM
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| 2 |
IC50 = 109 nM
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CP0388945
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C54H71N15O9
|
2
|
| 1 |
EC50 = 7 nM
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|
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| 2 |
IC50 = 6.9 nM
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CP0045108
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(4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S)-6-amino-1-[(2S)-2-{[(1S)-1-carbamoyl-2-methylpropyl]carbamoyl}pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}methyl)carbamoyl]-2-(1H-indol-3-yl)ethyl]carbamoyl}-4-carbamimidamidobutyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-(1H-imidazol-5-yl)ethyl]carbamoyl}-4-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-acetamido-3-hydroxypropanamido]-3-(4-hydroxyphenyl)propanamido]-3-hydroxypropanamido]-4-(methylsulfanyl)butanamido]butanoic acid
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|
C77H109N21O19S
|
5
|
| 1 |
EC50 = 8.1 nM
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|
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| 2 |
EC50 = 29 nM
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| 3 |
EC50 = 35.3 nM
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| 4 |
EC50 = 360 nM
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| 5 |
IC50 = 18 nM
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CP0390103
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(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-2-oxoethyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]pentanoic acid
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|
C77H111N21O18S
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2
|
| 1 |
EC50 = 8.1 nM
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| 2 |
IC50 = 18 nM
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CP0377559
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(3S,9S,17S,20S,23S,26R,29S)-9-[[(2S)-2-acetamidohexanoyl]amino]-23-[3-(diaminomethylideneamino)propyl]-20-(1H-indol-3-ylmethyl)-26-(naphthalen-2-ylmethyl)-2,8,11,19,22,25,28-heptaoxo-1,7,12,18,21,24,27-heptazatricyclo[27.3.0.03,7]dotriacontane-17-carboxamide
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|
C58H78N14O10
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2
|
| 1 |
EC50 = 10.1 nM
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| 2 |
IC50 = 300 nM
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CP0402649
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(5S,8R,11S,14S,17S)-8-benzyl-11-[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-2,2-dimethyl-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
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|
C41H53N13O7
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2
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| 1 |
EC50 = 14 nM
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| 2 |
IC50 = 440 nM
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CP0390482
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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|
C74H102N20O15
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2
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| 1 |
EC50 = 16 nM
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| 2 |
IC50 = 18 nM
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CP0383562
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(5S,8R,11S,14S,17S)-11-[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-2,2-dimethyl-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,19-hexaoxo-1,4,7,10,13,16-hexazacyclononadecane-17-carboxamide
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C44H53N13O7
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2
|
| 1 |
EC50 = 18 nM
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| 2 |
IC50 = 165 nM
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CP0377558
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(3R,6R,14R,17S,20S,23S,26R)-6-[[(2S)-2-acetamidohexanoyl]amino]-20-[3-(diaminomethylideneamino)propyl]-3,17-bis(1H-indol-3-ylmethyl)-23-(naphthalen-2-ylmethyl)-2,5,8,16,19,22,25-heptaoxo-1,4,9,15,18,21,24-heptazabicyclo[24.3.0]nonacosane-14-carboxamide
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|
C64H81N15O10
|
2
|
| 1 |
EC50 = 20 nM
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| 2 |
IC50 = 580 nM
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CP0375708
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Ac-Nle-c[Asp-cis-4-guanidinyl-Pro-DPhe-Arg-Trp-Lys]-NH2
Show/Hide
|
C50H72N16O9
|
2
|
| 1 |
EC50 = 21 nM
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| 2 |
IC50 = 1.1 nM
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CP0384356
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(7S,10R,13S,16S,19S)-13-[3-(diaminomethylideneamino)propyl]-16-(1H-indol-3-ylmethyl)-10-(naphthalen-2-ylmethyl)-2,8,11,14,17,28-hexaoxo-3,9,12,15,18,24-hexazatricyclo[27.4.0.03,7]tritriaconta-1(33),29,31-triene-19-carboxamide
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|
C52H63N11O7
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2
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| 1 |
EC50 = 23 nM
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| 2 |
IC50 = 27 nM
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CP0389089
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(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
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|
C34H42N8O5
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2
|
| 1 |
EC50 = 37 nM
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| 2 |
IC50 = 46 nM
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CP0870111
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(3R,6S,9S,12R,15S)-12-benzyl-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-6-(1H-indol-3-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
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|
C42H47N13O8S
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2
|
| 1 |
EC50 = 44 nM
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| 2 |
IC50 = 190 nM
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CP0545381
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-4,4-dimethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.2.2]octacosa-1(26),24,27-triene-5-carboxamide
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C56H74N14O8S2
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2
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| 1 |
EC50 = 48 nM
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| 2 |
IC50 = 69 nM
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CP0400882
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1-methyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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|
C55H73N15O9
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2
|
| 1 |
EC50 = 60 nM
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| 2 |
IC50 = 6.1 nM
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CP0378891
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,10,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C57H77N15O9
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2
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| 1 |
EC50 = 62.52 nM
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| 2 |
IC50 = 571.5 nM
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CP0374300
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(3S,6S,9R,12S,15S,23S)-15-[[(2S)-2-acetamidohexanoyl]amino]-9-benzyl-6-[3-(diaminomethylideneamino)propyl]-12-(4H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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|
C50H69N15O9
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1
|
| 1 |
EC50 = 69 nM
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CP0377557
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(3S,6S,14S,17R,20R,23R,26S)-6-[[(2R)-2-acetamidohexanoyl]amino]-23-benzyl-20-[3-(diaminomethylideneamino)propyl]-3,17-bis(1H-indol-3-ylmethyl)-2,5,8,16,19,22,25-heptaoxo-1,4,9,15,18,21,24-heptazabicyclo[24.3.0]nonacosane-14-carboxamide
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C60H79N15O10
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2
|
| 1 |
EC50 = 73 nM
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| 2 |
IC50 > 1000 nM
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CP0376106
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-(carboxymethylamino)-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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|
C75H101N21O16
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2
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| 1 |
EC50 = 82 nM
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| 2 |
IC50 = 636 nM
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CP0376199
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(3S)-3-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-5-carbamimidamido-1-[[(2S)-1-(carboxymethylamino)-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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|
C74H99N21O16S
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2
|
| 1 |
EC50 = 82 nM
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| 2 |
IC50 = 340 nM
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CP0387782
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Ac-Nle-c[Asp-cis-4-guanidinyl-Pro-DNal(2')-Arg-Trp-Lys]-NH2
Show/Hide
|
C54H74N16O9
|
2
|
| 1 |
EC50 = 85 nM
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|
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| 2 |
IC50 = 2.2 nM
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CP0383561
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(9S,12S,15S,18R,21S)-15-[3-(diaminomethylideneamino)propyl]-21-(1H-imidazol-5-ylmethyl)-12-(1H-indol-3-ylmethyl)-18-(naphthalen-2-ylmethyl)-7,11,14,17,20,23-hexaoxo-6,10,13,16,19,22-hexazaspiro[4.18]tricosane-9-carboxamide
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|
C46H55N13O7
|
2
|
| 1 |
EC50 = 96 nM
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| 2 |
IC50 = 160 nM
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CP0382502
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-aminooxy-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C75H102N22O16
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2
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| 1 |
EC50 = 99 nM
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| 2 |
IC50 = 200 nM
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CP0437025
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(4R,7S,10S,13R,16S,19S,22R)-22-[[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]amino]-13-benzyl-16-(1H-imidazol-5-ylmethyl)-7-(1H-indol-3-ylmethyl)-10,19-dimethyl-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexazacyclotricosane-4-carboxamide
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C46H61N15O9S2
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1
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| 1 |
EC50 = 109.7 nM
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CP0551927
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-21,21-dimethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(28),24,26-triene-5-carboxamide
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C56H74N14O8S2
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2
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| 1 |
EC50 = 126 nM
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| 2 |
IC50 = 93.5 nM
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CP0507015
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-3-[[(2S)-2-aminopropanoyl]amino]-9-benzyl-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C48H63N17O9S
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1
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| 1 |
EC50 = 137 nM
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CP0404107
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(5S,8R,11S,14S,17S)-8-benzyl-11-[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-2,2-dimethyl-3,6,9,12,15,19-hexaoxo-1,4,7,10,13,16-hexazacyclononadecane-17-carboxamide
Show/Hide
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C40H51N13O7
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2
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| 1 |
EC50 = 140 nM
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| 2 |
IC50 > 1000 nM
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CP0228070
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6-(3-Guanidino-propyl)-12-(3H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-9-naphthalen-2-ylmethyl-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotricosane-23-carboxylic acid amide
Show/Hide
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C46H57N13O7
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2
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| 1 |
EC50 = 150 nM
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| 2 |
Ki = 140 nM
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CP0382079
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4-methyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C55H73N15O9
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2
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| 1 |
EC50 = 169 nM
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| 2 |
IC50 = 16.8 nM
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CP0402648
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(10S,13S,16S,19R,22S)-16-[3-(diaminomethylideneamino)propyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-19-(naphthalen-2-ylmethyl)-8,12,15,18,21,24-hexaoxo-7,11,14,17,20,23-hexazaspiro[5.18]tetracosane-10-carboxamide
Show/Hide
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C47H57N13O7
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2
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| 1 |
EC50 = 170 nM
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| 2 |
IC50 > 1000 nM
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CP0432502
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(2S,5S,8R,11S,14S,17S)-8-benzyl-2-butyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-5-propan-2-yl-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C42H59N11O7
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2
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| 1 |
EC50 = 180 nM
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| 2 |
IC50 = 110 nM
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CP0444827
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(2R,5S,8S,11S,19S)-19-[(2S)-2-aminohexanamido]-5-(3-carbamimidamidopropyl)-2-[(4-chlorophenyl)methyl]-8-(1H-indol-3-ylmethyl)-3,6,9,17,20,31-hexaoxo-1,4,7,10,16,21-hexaazatricyclo[20.8.1.0^{24,29}]hentriaconta-24(29),25,27-triene-11-carboxamide
Show/Hide
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C52H68ClN13O8
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2
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| 1 |
EC50 = 180 nM
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| 2 |
IC50 = 123 nM
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CP0432503
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(2S,5S,8R,11S,14S,17S)-2,5-dibutyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C47H63N11O7
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2
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| 1 |
EC50 = 200 nM
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| 2 |
IC50 = 3.8 nM
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CP0393262
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(3S)-3-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-aminooxy-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C77H103N21O16
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2
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| 1 |
EC50 = 200 nM
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| 2 |
IC50 = 5 nM
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CP0388943
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,7,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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2
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| 1 |
EC50 = 239 nM
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| 2 |
IC50 = 2.82 nM
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CP0863666
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H-Tyr-Val-Nle-Gly-Pro-Phe-Arg-D-Nal(2'')-Asp-Arg-Phe-Gly-NH2
Show/Hide
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C76H102N18O16
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2
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| 1 |
EC50 = 250 nM
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| 2 |
IC50 = 650 nM
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CP0390462
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
Show/Hide
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C51H70N18O9S
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1
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| 1 |
EC50 = 298.7 nM
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CP0432500
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(2S,5R,8R,11S,14S,17S)-5-(3-amino-3-oxopropyl)-8-benzyl-2-butyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C42H58N12O8
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2
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| 1 |
EC50 = 300 nM
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| 2 |
IC50 = 500 nM
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CP0437027
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-15-(1H-indol-3-ylmethyl)-6-methyl-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
Show/Hide
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C48H68N16O9S
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1
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| 1 |
EC50 = 375.2 nM
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CP0407278
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C74H100N22O15S
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2
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| 1 |
EC50 = 390 nM
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| 2 |
IC50 = 330 nM
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CP0376683
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(3S)-3-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-aminooxy-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C75H102N22O16
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2
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| 1 |
EC50 = 410 nM
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| 2 |
IC50 = 11 nM
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CP0389097
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(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
Show/Hide
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C34H41ClN8O5
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1
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| 1 |
EC50 = 433 nM
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CP0388946
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,7-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C56H75N15O9
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2
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| 1 |
EC50 = 446 nM
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| 2 |
IC50 = 6 nM
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CP0376220
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,7-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C56H75N15O9
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2
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| 1 |
EC50 = 460 nM
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| 2 |
IC50 = 16.46 nM
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CP0410091
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-phenylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-aminooxy-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C77H103N21O16
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2
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| 1 |
EC50 = 490 nM
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| 2 |
IC50 = 3.3 nM
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CP0099822
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CAS_72711-43-4
Show/Hide
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C74H99N21O16S
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2
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| 1 |
EC50 = 550 nM
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| 2 |
IC50 = 2200 nM
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CP0197083
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9-Benzyl-6-(3-guanidino-propyl)-12-(3H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotricosane-23-carboxylic acid amide
Show/Hide
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C42H55N13O7
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2
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| 1 |
EC50 = 560 nM
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| 2 |
Ki = 660 nM
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CP0389079
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(8S,11S,14S,17R,20S)-14-[3-(diaminomethylideneamino)propyl]-20-(1H-imidazol-5-ylmethyl)-11-(1H-indol-3-ylmethyl)-17-(naphthalen-2-ylmethyl)-6,10,13,16,19,22-hexaoxo-5,9,12,15,18,21-hexazaspiro[3.18]docosane-8-carboxamide
Show/Hide
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C45H53N13O7
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2
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| 1 |
EC50 = 560 nM
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| 2 |
IC50 > 1000 nM
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CP0384353
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(11S,14S,17S,20R,23S)-20-benzyl-17-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-2,13,16,19,22-pentaoxo-1,6,12,15,18,21-hexazabicyclo[21.3.0]hexacosane-11-carboxamide
Show/Hide
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C41H57N11O6
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2
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| 1 |
EC50 = 570 nM
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| 2 |
IC50 = 870 nM
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CP0436848
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]propanoic acid
Show/Hide
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C49H66N18O9
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1
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| 1 |
EC50 = 635 nM
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CP0094502
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(O)C-(C6H4)-C(O)-c[His-D-Nal(2')-Arg-Trp-Lys]-NH2) (MK-7)
Show/Hide
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C50H57N13O7
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2
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| 1 |
EC50 = 640 nM
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| 2 |
Ki = 5700 nM
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CP0390464
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-3-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-9-benzyl-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
Show/Hide
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C51H70N20O9S
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1
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| 1 |
EC50 = 752.3 nM
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CP0376209
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,7,10,13-tetramethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C58H79N15O9
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2
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| 1 |
EC50 = 818 nM
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| 2 |
IC50 = 1050 nM
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CP0382076
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,7,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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2
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| 1 |
EC50 = 838 nM
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| 2 |
IC50 = 871 nM
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CP0403239
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(3S,8S,11S,14S,17R,20R)-17-benzyl-3-butyl-14-[3-(diaminomethylideneamino)propyl]-11-(1H-indol-3-ylmethyl)-2,5,10,13,16,19-hexaoxo-1,4,9,12,15,18-hexazabicyclo[18.3.0]tricosane-8-carboxamide
Show/Hide
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C42H57N11O7
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2
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| 1 |
EC50 = 850 nM
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| 2 |
IC50 = 400 nM
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CP0376105
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-aminooxy-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C82H106N20O16
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2
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| 1 |
EC50 = 870 nM
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| 2 |
IC50 = 1000 nM
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CP0437028
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(2S)-2-[[(2S,5S,8R,11S,14S,17S)-8-benzyl-2,11-bis[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13,16,20,21-octazabicyclo[17.2.1]docosa-19(22),20-diene-17-carbonyl]amino]-4-methylsulfanylbutanoic acid
Show/Hide
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C48H64N18O8S
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1
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| 1 |
EC50 = 916 nM
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CP0374304
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((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridin-2-yl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
Show/Hide
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C29H31F2N3O2
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1
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| 1 |
EC50 = 960 nM
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CP0400431
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-7-methyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C55H73N15O9
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2
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| 1 |
EC50 = 1060 nM
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| 2 |
IC50 = 3.41 nM
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CP0341428
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4-[[(2S)-1-[[(2R)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C42H57N13O8
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2
|
| 1 |
EC50 = 1100 nM
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| 2 |
Ki = 880 nM
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CP0652962
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22-Benzyl-19-(3-guanidino-propyl)-16-(1H-indol-3-ylmethyl)-4,7,15,18,21,24-hexaoxo-docosahydro-3a,8,14,17,20,23-hexaaza-cyclopentacyclotricosene-13-carboxylic acid amide
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C41H55N11O7
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2
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| 1 |
EC50 = 1300 nM
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| 2 |
Ki = 990 nM
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CP0374314
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((3R,4S)-1-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
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C28H36F2N2O2
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1
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| 1 |
EC50 = 1430 nM
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CP0382072
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,10,13-tetramethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C58H79N15O9
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2
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| 1 |
EC50 = 1450 nM
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| 2 |
IC50 = 4290 nM
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CP0376211
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,7,10,13-tetramethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C58H79N15O9
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2
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| 1 |
EC50 = 1520 nM
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| 2 |
IC50 = 177 nM
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CP0376217
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C56H75N15O9
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2
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| 1 |
EC50 = 1560 nM
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| 2 |
IC50 = 15 nM
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CP0378892
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-7,10,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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2
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| 1 |
EC50 = 1680 nM
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| 2 |
IC50 = 115 nM
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CP0374301
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((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4R,5R)-4-(3-fluorophenyl)-4-hydroxy-3,5-dimethylpiperidin-1-yl)methanone
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C28H35F3N2O2
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1
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| 1 |
EC50 = 1800 nM
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CP0849936
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(3R,4R,5S)-1-{[(3S,4R)-1-tert-Butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl]carbonyl}-3,5-dimethyl-4-phenylpiperidin-4-ol Hydrochloride
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C28H37ClF2N2O2
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1
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| 1 |
EC50 = 1980 nM
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CP0375709
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Ac-Nle-c[Asp-His-DNal(2')-trans-4-guanidinyl-Pro-Trp-Lys]-NH2
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C54H69N15O9
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2
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| 1 |
EC50 = 2400 nM
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| 2 |
IC50 = 22 nM
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CP0372162
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Ac-Nle-c[Asp-His-DPhe-trans-4-guanidinyl-Pro-Trp-Lys]-NH2
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C50H67N15O9
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2
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| 1 |
EC50 = 2500 nM
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| 2 |
IC50 = 590 nM
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CP0149367
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(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-(4-cyclohexyl-4-[1,2,4]triazol-1-ylmethyl-piperidin-1-yl)-2-oxo-ethyl]-amide
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C33H41ClN6O2
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2
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| 1 |
EC50 = 2700 nM
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| 2 |
Ki = 860 nM
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CP0391042
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((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4R,5R)-4-(2,4-difluorophenyl)-4-hydroxy-3,5-dimethylpiperidin-1-yl)methanone
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C28H34F4N2O2
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1
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| 1 |
EC50 = 3500 nM
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CP0845107
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(3R,4R,5S)-1-{[(3S,4R)-1-tert-Butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl]carbonyl}-4-(4-fluorophenyl)-3,5-dimethylpiperidin-4-ol Hydrochloride
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C28H36ClF3N2O2
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1
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| 1 |
EC50 = 3600 nM
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CP0383468
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((3S,4R)-4-(2,4-difluorophenyl)-1-isopropylpyrrolidin-3-yl)((3S,4R,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
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C27H34F2N2O2
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1
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| 1 |
EC50 = 3640 nM
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CP0866921
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(S)-2-((R)-2-((S)-4-acetamido-3-oxo-4,5-dihydroazepino[3,4-b]indol-2(1H,3H,10H)-yl)-3-(4-fluorophenyl)propanamido)-N-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-5-guanidinopentanamide
Show/Hide
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C40H45FN10O5
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2
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| 1 |
EC50 = 4112 nM
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| 2 |
IC50 = 167 nM
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CP0401418
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((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4R,5R)-4-(4-chlorophenyl)-4-hydroxy-3,5-dimethylpiperidin-1-yl)methanone
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C28H35ClF2N2O2
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1
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| 1 |
EC50 = 5190 nM
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CP0391026
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((3S,4R)-4-(2,4-difluorophenyl)-1-ethylpyrrolidin-3-yl)((3S,4R,5R)-4-(3-fluorophenyl)-4-hydroxy-3,5-dimethylpiperidin-1-yl)methanone
Show/Hide
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C26H31F3N2O2
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1
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| 1 |
EC50 = 6410 nM
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CP0096571
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9-Benzyl-6-(3-guanidino-propyl)-3-(1H-indol-3-ylmethyl)-12-methyl-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotricosane-23-carboxylic acid amide
Show/Hide
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C39H53N11O7
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1
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| 1 |
EC50 > 10000 nM
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CP0103609
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9-Benzyl-12-(3H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-6-methyl-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotricosane-23-carboxylic acid amide
Show/Hide
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C39H48N10O7
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1
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| 1 |
EC50 > 10000 nM
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CP0103613
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6-(3-Guanidino-propyl)-12-(3H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-9-methyl-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotricosane-23-carboxylic acid amide
Show/Hide
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C36H51N13O7
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1
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| 1 |
EC50 > 10000 nM
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CP0184588
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5-Benzyl-8-(3-guanidino-propyl)-2-(3H-imidazol-4-ylmethyl)-11-(1H-indol-3-ylmethyl)-3,6,9,12,20,24-hexaoxo-1,4,7,10,13,19hexaaza-cyclotetracosane-14-carboxylic acid amide
Show/Hide
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C43H57N13O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
Ki = 3100 nM
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CP0371887
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4-[(3S,8aS)-3-benzyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-N-[2-(1H-indol-3-yl)ethyl]-4-oxobutanamide
Show/Hide
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C28H34N4O2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 0.5 nM
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CP0371892
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1-((3R,8aS)-3-benzyl-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-3-(1H-indol-3-yl)propan-1-one
Show/Hide
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C25H29N3O
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0371896
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4-[(3R,8aS)-3-benzyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-N-[2-(1H-indol-3-yl)ethyl]-4-oxobutanamide
Show/Hide
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C28H34N4O2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 0.1 nM
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CP0381774
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N-[(2S)-1-[(3S,8aS)-3-benzyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-3-(1H-indol-3-yl)propanamide
Show/Hide
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C31H41N7O2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 0.1 nM
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CP0381776
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1-((3R,8aS)-3-benzyl-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-phenylethanone
Show/Hide
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C22H26N2O
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0381777
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N-[6-[(3S,8aS)-3-benzyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-6-oxohexyl]-3-(1H-indol-3-yl)propanamide
Show/Hide
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C31H40N4O2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 0.4 nM
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CP0381817
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1-((3S,8aS)-3-benzyl-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-phenylethanone
Show/Hide
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C22H26N2O
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0424734
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1-((3S,8aS)-3-benzyl-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-3-(1H-indol-3-yl)propan-1-one
Show/Hide
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C25H29N3O
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 0.8 nM
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CP0378867
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(2S,5S,8R,11S,14S,17S)-2-butyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-5-propan-2-yl-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C46H61N11O7
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3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 2.2 nM
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| 3 |
Kd = 1.995 nM
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CP0403235
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(2S,5R,8R,11S,14S,17S)-2-butyl-5,11-bis[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C47H64N14O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 2.3 nM
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CP0403236
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2-[(2S,5S,8R,11S,14S,17S)-8-benzyl-2-butyl-17-carbamoyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicos-5-yl]acetic acid
Show/Hide
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C41H55N11O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0403237
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(2S,5R,8R,11S,14S,17S)-8-benzyl-2-butyl-5,11-bis[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C43H62N14O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 68 nM
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CP0403238
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(2S,5S,8R,11S,14S,17S)-8-benzyl-2,5-dibutyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C43H61N11O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 70 nM
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CP0432499
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(2S,5S,8R,11S,14S,17S)-8-benzyl-2-butyl-11-[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C43H57N13O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 100 nM
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CP0432501
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2-[(2S,5R,8R,11S,14S,17S)-2-butyl-17-carbamoyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicos-5-yl]acetic acid
Show/Hide
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C45H57N11O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 220 nM
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CP0432514
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(2S,5S,8R,11S,14S,17S)-5-(3-amino-3-oxopropyl)-2-butyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C46H60N12O8
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 1.4 nM
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CP0432515
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3-[(2S,5R,8R,11S,14S,17S)-8-benzyl-2-butyl-17-carbamoyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicos-5-yl]propanoic acid
Show/Hide
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C42H57N11O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 3060 nM
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CP0441512
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3-[(2S,5S,8R,11S,14S,17S)-2-butyl-17-carbamoyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicos-5-yl]propanoic acid
Show/Hide
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C46H59N11O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 44 nM
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CP0441513
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(2S,5S,8R,11S,14S,17S)-2-butyl-11-[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C47H59N13O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 2.3 nM
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CP0442492
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(3S,8S,11S,14S,17R,20S)-3-butyl-14-[3-(diaminomethylideneamino)propyl]-11-(1H-indol-3-ylmethyl)-17-(naphthalen-2-ylmethyl)-2,5,10,13,16,19-hexaoxo-1,4,9,12,15,18-hexazabicyclo[18.3.0]tricosane-8-carboxamide
Show/Hide
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C46H59N11O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 10 nM
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CP0444828
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(2R,5S,8S,11S,19S)-19-[(2S)-2-aminohexanamido]-2-benzyl-5-(3-carbamimidamidopropyl)-8-(1H-indol-3-ylmethyl)-3,6,9,17,20,31-hexaoxo-1,4,7,10,16,21-hexaazatricyclo[20.8.1.0^{24,29}]hentriaconta-24(29),25,27-triene-11-carboxamide
Show/Hide
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C52H69N13O8
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 2900 nM
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CP0462965
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(S)-3-((R)-2-acetamidohexanamido)-4-(2-((S)-1-((S)-1-((S)-1-((S)-1,6-diamino-1-oxohexan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-5-guanidino-1-oxopentan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-ylamino)
Show/Hide
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C54H73N13O10
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0485356
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(2R,5S,8S,11S,19S)-19-[(2S)-2-aminohexanamido]-5-(3-carbamimidamidopropyl)-8-(1H-indol-3-ylmethyl)-2-(naphthalen-2-ylmethyl)-3,6,9,17,20,31-hexaoxo-1,4,7,10,16,21-hexaazatricyclo[20.8.1.0^{24,29}]hentriaconta-24(29),25,27-triene-11-carboxamide
Show/Hide
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C56H71N13O8
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 87 nM
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CP0376205
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-10-methyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C55H73N15O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 27.7 nM
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CP0376215
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,10-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 592 nM
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CP0376219
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,13-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C56H75N15O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 13 nM
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CP0376246
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,7,10,13-pentamethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C59H81N15O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 257 nM
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CP0376248
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-7,10-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C56H75N15O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 35.2 nM
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CP0378890
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,7-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C57H77N15O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 6.66 nM
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CP0382073
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-7,13-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C56H75N15O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 6.33 nM
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CP0382077
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,7,10-tetramethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C58H79N15O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 1510 nM
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CP0382100
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-13-methyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C55H73N15O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 5 nM
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CP0400880
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,10-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C56H75N15O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 95 nM
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CP0400881
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-10,13-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C56H75N15O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 1670 nM
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CP0374303
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((3R,4S)-4-(2,4-difluorophenyl)-1-(pyrimidin-2-yl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
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C28H30F2N4O2
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1
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| 1 |
EC50 > 11100 nM
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CP0383465
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((3R,4S)-4-(2,4-difluorophenyl)-1-(pyrimidin-4-yl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
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C28H30F2N4O2
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1
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| 1 |
EC50 > 14000 nM
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CP0401674
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((3S,4R)-4-(2,4-difluorophenyl)-1-methylpyrrolidin-3-yl)((3S,4R,5R)-4-(4-fluorophenyl)-4-hydroxy-3,5-dimethylpiperidin-1-yl)methanone
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C25H29F3N2O2
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1
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| 1 |
EC50 = 15000 nM
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CP0402317
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((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4R,5R)-4-hydroxy-3,5-dimethyl-4-(pyridin-2-yl)piperidin-1-yl)methanone
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C27H35F2N3O2
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1
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| 1 |
EC50 = 17800 nM
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CP0383467
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((3S,4R)-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4R,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
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C24H28F2N2O2
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1
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| 1 |
EC50 > 20000 nM
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CP0400031
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((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridazin-3-yl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
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C28H30F2N4O2
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1
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| 1 |
EC50 > 20000 nM
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CP0402318
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((3R,4S)-4-(2,4-difluorophenyl)-1-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
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C29H36F2N2O3
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1
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| 1 |
EC50 > 20000 nM
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CP0858960
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(3R,4R,5S)-1-{[(3S,4R)-4-(2,4-Difluorophenyl)-1-methylpyrrolidin-3-yl]carbonyl}-3,5-dimethyl-4-phenylpiperidin-4-ol Hydrochloride
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C25H31ClF2N2O2
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1
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| 1 |
EC50 = 20000 nM
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CP0389236
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[2-[[(2S)-5-amino-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[(2S)-2-[[(2S,3S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-6-amino-1-[[(2S,3S)-1-[[(2S)-5-amino-1-[[2-[[(2S,3R)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2R)-1-[[(2R)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-2-oxoethyl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
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C167H263N49O49S6
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1
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| 1 |
EC50 > 100000 nM
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CP0393623
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(3S)-3-amino-4-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-6-amino-1-[[(1R,6aR,7S,10S,13S,16S,19S,22S,25S,31S,34S,37S,43S,46S,49S,55S,58S,61R,66R,69S,72S,75S,84S,88R,90S,93S,96S,99S)-19,37,49-tris(4-aminobutyl)-13,58-bis(2-amino-2-oxoethyl)-25,72-bis(3-amino-3-oxopropyl)-84-benzyl-93-(3-carbamimidamidopropyl)-46-(carboxymethyl)-6a-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]-16,31-bis[(1R)-1-hydroxyethyl]-10,96,99-tris(hydroxymethyl)-75-(1H-imidazol-5-ylmethyl)-22,69,90-tris(2-methylpropyl)-a,2,8,8a,11,14,17,20,23,26,29,32,35,38,44,47,50,56,59,67,70,73,76,79,82,85,87,91,94,97-triacontaoxo-3a,4a,10a,11a,63,64-hexathia-1a,3,7a,9,12,15,18,21,24,27,30,33,36,39,45,48,51,57,60,68,71,74,77,80,83,86,89,92,95,98-triacontazahexacyclo[59.40.7.434,88.03,7.039,43.051,55]dodecahectan-66-yl]amino]-1-oxohexan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-oxobutanoic acid
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C165H262N52O51S6
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1
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| 1 |
EC50 > 100000 nM
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CP0396404
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(3S)-3-amino-4-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[(2S)-2-[[(2S)-1-[[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-5-amino-1-[[2-[[(2S,3R)-1-[[(2R)-1-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-1-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-4-amino-1-[[(2R)-1-[[(2R)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1,4-dioxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-sulfanylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-oxobutanoic acid
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C165H268N52O51S6
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1
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| 1 |
EC50 > 100000 nM
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CP0436883
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(aR,1R,6S,9S,12S,15S,18S,21S,24S,30S,33R,36S,39S,45S,48S,51S,54R,59R,62S,65S,68S,77S,80R,83S,86R,89S,92S)-18,45,51-tris(4-aminobutyl)-24-(3-amino-3-oxopropyl)-12-benzyl-9,21-bis[(2S)-butan-2-yl]-39-(3-carbamimidamidopropyl)-77-(2-carboxyethyl)-a-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]-15,30-bis[(1R)-1-hydroxyethyl]-65,68,89-tris(hydroxymethyl)-36,86-bis[(4-hydroxyphenyl)methyl]-48,92-dimethyl-83-(2-methylpropyl)-2a,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,63,66,69,72,75,78,81,84,87,90,93,95-triacontaoxo-62-propan-2-yl-4a,5a,56,57,97,98-hexathia-1a,2,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,61,64,67,70,73,76,79,82,85,88,91,94-triacontazatetracyclo[52.41.7.433,80.02,6]hexahectan-59-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
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C167H256N48O50S6
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1
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| 1 |
EC50 > 100000 nM
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CP0437026
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-15-methyl-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C43H65N17O9S
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1
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| 1 |
EC50 >= 809 nM
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CP0378448
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(2R,5S,8S,11S,25S)-25-amino-2-benzyl-5-[3-(diaminomethylideneamino)propyl]-8-(1H-indol-3-ylmethyl)-3,6,9,17,20,26-hexaoxo-1,4,7,10,16-pentazacyclohexacosane-11-carboxamide
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C42H59N11O7
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 520 nM
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CP0407277
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C73H100N20O15S
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 36 nM
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CP0389091
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(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-bromophenyl)propanoyl]amino]-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
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C34H41BrN8O5
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1
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| 1 |
EC50 > 1000 nM
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CP0389092
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(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-[4-(trifluoromethyl)phenyl]propanoyl]amino]-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
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C35H41F3N8O5
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 37 nM
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CP0545380
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.4.0]octacosa-1(28),24,26-triene-5-carboxamide
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C54H70N14O8S2
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 78 nM
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CP0547334
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carboxamide
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C54H70N14O8S2
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 4.4 nM
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CP0550596
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.2.2]octacosa-1(26),24,27-triene-5-carboxamide
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C54H70N14O8S2
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 2 nM
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CP0551926
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-4,4-dimethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carboxamide
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C56H74N14O8S2
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 30 nM
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CP0376213
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,10-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C56H75N15O9
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2
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| 1 |
EC50 > 2000 nM
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| 2 |
IC50 = 2260 nM
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CP0381782
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,7,10-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C57H77N15O9
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2
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| 1 |
EC50 > 2000 nM
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| 2 |
IC50 = 159 nM
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CP0400476
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,13-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C56H75N15O9
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2
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| 1 |
EC50 > 2000 nM
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| 2 |
IC50 = 91 nM
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CP0269557
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(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-oxo-2-[4-(2-[1,2,4]triazol-1-ylmethyl-phenyl)-piperazin-1-yl]-ethyl}-amide
Show/Hide
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C32H34ClN7O2
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2
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| 1 |
EC50 > 3000 nM
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| 2 |
Ki = 1200 nM
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CP0393281
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(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-oxo-2-[4-(2-[1,2,4]triazol-4-ylmethyl-phenyl)-piperazin-1-yl]-ethyl}-amide
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C32H34ClN7O2
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1
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| 1 |
EC50 > 3000 nM
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CP0388955
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,7,10-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C57H77N15O9
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2
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| 1 |
EC50 > 3000 nM
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|
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| 2 |
IC50 = 39.7 nM
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CP0390467
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-9-methyl-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C45H66N18O9S
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1
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| 1 |
EC50 > 3000 nM
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CP0410709
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(2S)-2-[[(3S,6S,9S,12S,15S,18S)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C51H70N18O9S
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1
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| 1 |
EC50 > 3000 nM
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CP0410710
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-15-(1-benzothiophen-3-ylmethyl)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C51H69N17O9S2
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1
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| 1 |
EC50 > 3000 nM
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CP0410711
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-9-[(2R)-butan-2-yl]-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C48H72N18O9S
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1
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| 1 |
EC50 > 3000 nM
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CP0436850
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-15-(1H-imidazol-5-ylmethyl)-6-(1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C51H70N18O9S
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1
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| 1 |
EC50 > 3000 nM
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CP0436853
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-12-(4-aminobutyl)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C51H70N16O9S
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1
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| 1 |
EC50 > 3000 nM
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CP0436854
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-12-(3-aminopropyl)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
Show/Hide
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C50H68N16O9S
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1
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| 1 |
EC50 > 3000 nM
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CP0456638
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(2S)-2-[[(5S,8S,11R,14S,17S,20S)-5-amino-11-benzyl-14-[3-(diaminomethylideneamino)propyl]-8-(1H-imidazol-5-ylmethyl)-17-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,7,10,13,16,19,23,24-octazabicyclo[20.2.1]pentacosa-22(25),23-diene-20-carbonyl]amino]-4-methylsulfanylbutanoic acid
Show/Hide
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C47H62N16O8S
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1
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| 1 |
EC50 > 3000 nM
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CP0495602
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-15-(naphthalen-2-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
Show/Hide
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C53H71N17O9S
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1
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| 1 |
EC50 > 3000 nM
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|
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CP0507016
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-12-methyl-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
Show/Hide
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C48H63N15O9S
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1
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| 1 |
EC50 > 3000 nM
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CP0184629
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(O)C-(C6H4)-C(O)-c[His-D-Phe-Arg-Trp-Lys]-NH2) (MK-6)
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C46H55N13O7
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1
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| 1 |
EC50 > 5000 nM
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|
|
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CP0376207
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,10,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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2
|
| 1 |
EC50 > 5000 nM
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|
|
| 2 |
IC50 = 388 nM
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CP0462856
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((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4R,5R)-4-(2,6-difluorophenyl)-4-hydroxy-3,5-dimethylpiperidin-1-yl)methanone
Show/Hide
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C28H34F4N2O2
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1
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| 1 |
EC50 > 5810 nM
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|
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CP0407275
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C74H101N17O15
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1
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| 1 |
IC50 = 0.42 nM
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CP0393261
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(3S)-3-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-aminooxy-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C80H105N19O16
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1
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| 1 |
IC50 = 2 nM
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CP0393258
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-(carboxymethylamino)-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C79H103N21O16
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1
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| 1 |
IC50 = 3.5 nM
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CP0674615
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H-Tyr-Val-Nle-Gly-His-D-Nal(2)-Arg-D-Trp-Asp-Arg-Phe-Gly-NH2
Show/Hide
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C79H104N22O15
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1
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| 1 |
IC50 = 3.5 nM
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CP0383563
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(5S,8R,11S,14S,17S)-11-[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-2,2-dimethyl-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C45H55N13O7
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1
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| 1 |
IC50 = 12 nM
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CP0412765
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(2R,5S,8S,11S,25S)-25-amino-5-[3-(diaminomethylideneamino)propyl]-8-(1H-indol-3-ylmethyl)-2-(naphthalen-2-ylmethyl)-3,6,9,17,20,26-hexaoxo-1,4,7,10,16-pentazacyclohexacosane-11-carboxamide
Show/Hide
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C46H61N11O7
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2
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| 1 |
IC50 = 17 nM
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|
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| 2 |
Kd = 1.995 nM
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CP0383565
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(11S,14S,17S,20R,23S)-17-[3-(diaminomethylideneamino)propyl]-23-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-20-(naphthalen-2-ylmethyl)-8,13,16,19,22,25-hexaoxo-7,12,15,18,21,24-hexazaspiro[5.19]pentacosane-11-carboxamide
Show/Hide
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C48H59N13O7
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1
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| 1 |
IC50 = 20 nM
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CP0429705
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(9S,12S,15S,18R,21S)-15-[3-(diaminomethylideneamino)propyl]-21-(1H-imidazol-5-ylmethyl)-12-(1H-indol-3-ylmethyl)-18-(naphthalen-2-ylmethyl)-6,11,14,17,20,23-hexaoxo-5,10,13,16,19,22-hexazaspiro[3.19]tricosane-9-carboxamide
Show/Hide
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C46H55N13O7
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1
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| 1 |
IC50 = 21 nM
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CP0848656
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(S)-2-((R)-2-((S)-4-acetamido-3-oxo-4,5-dihydro-1H-benzo[c]azepin-2(3H)-yl)-3-phenylpropanamido)-N-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-5-guanidinopentanamide
Show/Hide
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C38H45N9O5
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1
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| 1 |
IC50 = 37.3 nM
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CP0870113
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(3R,6S,9S,12R,15S)-12-benzyl-9-(3-carbamimidamidopropyl)-15-(cyclohexylmethyl)-6-(1H-indol-3-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
Show/Hide
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C45H55N11O8S
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1
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| 1 |
IC50 = 38 nM
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CP0545281
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-4,4-dimethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.4.0]octacosa-1(28),24,26-triene-5-carboxamide
Show/Hide
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C56H74N14O8S2
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1
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| 1 |
IC50 = 46 nM
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|
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CP0870609
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(7S,10R,13S,16S,19R)-10-benzyl-13-(3-carbamimidamidopropyl)-19-carbamoyl-16-(1H-indol-3-ylmethyl)-N-methyl-N,2,8,11,14,17-hexaoxo-21-thia-3,9,12,15,18-pentaazatricyclo[20.4.0.0^{3,7}]hexacosa-1(26),22,24-trien-25-aminium
Show/Hide
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C41H47N11O8S
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1
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| 1 |
IC50 = 58 nM
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CP0432640
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,38-dimethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
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C77H113N23O16S2
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1
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| 1 |
IC50 = 58.88 nM
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CP0865305
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(S)-2-((R)-2-((S)-4-acetamido-3-oxo-4,5-dihydroazepino[3,4-b]indol-2(1H,3H,10H)-yl)-3-(4-bromophenyl)propanamido)-N-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-5-guanidinopentanamide
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C40H45BrN10O5
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1
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| 1 |
IC50 = 70.3 nM
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CP0850181
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(3R,6S,9S,12S,25aS)-6-(3-carbamimidamidopropyl)-9-(1H-indol-3-ylmethyl)-3-(naphthalen-2-ylmethyl)-1,4,7,10,18,21-hexaoxo-1H,2H,3H,4H,5H,6H,7H,8H,9H,10H,11H,12H,13H,14H,15H,16H,17H,18H,21H,23H,24H,25H,25aH-pyrrolo[2,1-l]1,4,7,10,13,18-hexaazacyclotricosane-12-carboxamide
Show/Hide
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C45H55N11O7
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1
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| 1 |
IC50 = 120 nM
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|
|
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CP0858763
|
(3R,6S,9S,12S,15S)-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-6-(1H-indol-3-ylmethyl)-12-(naphthalen-2-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
Show/Hide
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C46H49N13O8S
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2
|
| 1 |
IC50 = 130 nM
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|
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| 2 |
Kd = 5.012 nM
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CP0848658
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(S)-2-((R)-2-((S)-7-acetamido-6-oxo-7,8-dihydro-4H-[1,2,3]triazolo[1,5-a][1,4]diazepin-5(6H)-yl)-3-phenylpropanamido)-N-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-5-guanidinopentanamide
Show/Hide
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C34H42N12O5
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1
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| 1 |
IC50 = 137 nM
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|
|
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CP0577292
|
(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-21,21-dimethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.4.0]octacosa-1(28),24,26-triene-5-carboxamide
Show/Hide
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C56H74N14O8S2
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1
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| 1 |
IC50 = 157 nM
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|
|
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CP0568756
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-4,4,21,21-tetramethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carboxamide
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C58H78N14O8S2
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1
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| 1 |
IC50 = 172 nM
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|
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CP0455645
|
BREMELANOTIDE
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C50H68N14O10
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1
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| 1 |
IC50 = 194.98 nM
|
|
|
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CP0376305
|
Ac-c[Cys-His-D-Nal(2)'-Cys]-N-alpha-guanidinylbutyl-D-Trp-NH2
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C43H52N12O6S2
|
1
|
| 1 |
IC50 = 209 nM
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|
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CP0378387
|
(7S,10R,13S,16S,19S)-13-[3-(diaminomethylideneamino)propyl]-16-(1H-indol-3-ylmethyl)-10-(naphthalen-2-ylmethyl)-2,8,11,14,17,25-hexaoxo-3,9,12,15,18,24-hexazatricyclo[24.4.0.03,7]triaconta-1(30),26,28-triene-19-carboxamide
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C49H57N11O7
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1
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| 1 |
IC50 = 210 nM
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|
|
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CP0378449
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(4R,7S,10S,13S)-7-[3-(diaminomethylideneamino)propyl]-10-(1H-indol-3-ylmethyl)-4-(naphthalen-2-ylmethyl)-2,5,8,11,19-pentaoxo-3,6,9,12,18,21,24-heptazabicyclo[18.4.0]tetracosa-1(24),20,22-triene-13-carboxamide
Show/Hide
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C42H48N12O6
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1
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| 1 |
IC50 = 230 nM
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|
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CP0402862
|
(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-5-carbamimidamido-1-[[(2S)-1-(carboxymethylamino)-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C75H101N21O16
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1
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| 1 |
IC50 = 254 nM
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CP0455642
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,38,47-trimethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
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C78H115N23O16S2
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1
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| 1 |
IC50 = 281.84 nM
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CP0858758
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(3R,6S,9S,12R,15S)-12-benzyl-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-6-(naphthalen-2-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
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C44H48N12O8S
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1
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| 1 |
IC50 = 340 nM
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CP0571200
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-21,21-dimethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.2.2]octacosa-1(26),24,27-triene-5-carboxamide
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C56H74N14O8S2
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1
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| 1 |
IC50 = 422 nM
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CP0543865
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-4,4,21,21-tetramethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.4.0]octacosa-1(28),24,26-triene-5-carboxamide
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C58H78N14O8S2
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1
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| 1 |
IC50 = 507 nM
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CP0858764
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(3R,6S,9S,12R)-12-benzyl-9-(3-carbamimidamidopropyl)-6-(1H-indol-3-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-1',3',3,4,5,6,7,8,9,10,11,12,13,14,16,17-hexadecahydro-2H-spiro[1,4,7,10,13,16-benzothiapentazacyclononadecine-15,2'-indene]-3-carboxamide
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C46H49N11O8S
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1
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| 1 |
IC50 = 560 nM
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CP0859091
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(S)-2-((R)-2-((S)-4-acetamido-3-oxo-4,5-dihydroazepino[3,4-b]indol-2(1H,3H,10H)-yl)-3-phenylpropanamido)-N-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-5-guanidinopentanamide
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C40H46N10O5
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1
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| 1 |
IC50 = 636 nM
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CP0432200
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25-methyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
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C76H111N23O16S2
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1
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| 1 |
IC50 = 707.95 nM
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CP0408822
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,38,41,47-tetramethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
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C79H117N23O16S2
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1
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| 1 |
IC50 = 758.58 nM
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|
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CP0870610
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(3R,6S,9S,12R,15S)-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-6-(1H-indol-3-ylmethyl)-12-(naphthalen-2-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
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C46H49N13O8S
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1
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| 1 |
IC50 = 760 nM
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CP0847693
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(3R,6S,9S,12S,25aS)-3-benzyl-6-(3-carbamimidamidopropyl)-9-(1H-indol-3-ylmethyl)-1,4,7,10,18,21-hexaoxo-1H,2H,3H,4H,5H,6H,7H,8H,9H,10H,11H,12H,13H,14H,15H,16H,17H,18H,21H,23H,24H,25H,25aH-pyrrolo[2,1-l]1,4,7,10,13,18-hexaazacyclotricosane-12-carboxamide
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C41H53N11O7
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1
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| 1 |
IC50 = 790 nM
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|
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CP0408810
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,38,41-trimethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
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C78H115N23O16S2
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1
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| 1 |
IC50 = 812.83 nM
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|
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CP0408806
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,41-dimethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
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C77H113N23O16S2
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1
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| 1 |
IC50 = 1122.02 nM
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CP0473015
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(2S)-2-acetamido-N-[(2R)-1-[[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-amino-1-oxo-3-sulfanylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide
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C49H70N18O9S2
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1
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| 1 |
IC50 = 1905.46 nM
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CP0408821
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43S,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25-methyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
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C76H111N23O16S2
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1
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| 1 |
IC50 = 4073.8 nM
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CP0408819
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,41,47-trimethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
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C78H115N23O16S2
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1
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| 1 |
IC50 = 4168.69 nM
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CP0408808
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,47-dimethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
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C77H113N23O16S2
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1
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| 1 |
IC50 = 6606.93 nM
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CP0432645
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-14,23-dimethyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
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C81H111N23O17S2
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1
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| 1 |
IC50 = 7079.46 nM
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CP0408813
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
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C79H107N23O17S2
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1
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| 1 |
IC50 = 8511.38 nM
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CP0378391
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(4R,7S,10S,13S)-4-benzyl-7-[3-(diaminomethylideneamino)propyl]-10-(1H-indol-3-ylmethyl)-2,5,8,11,19-pentaoxo-3,6,9,12,18,21,24-heptazabicyclo[18.4.0]tetracosa-1(24),20,22-triene-13-carboxamide
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C38H46N12O6
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1
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| 1 |
IC50 > 10000 nM
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CP0378445
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(4R,7S,10S,13S)-4-benzyl-7-[3-(diaminomethylideneamino)propyl]-10-(1H-indol-3-ylmethyl)-2,5,8,11,19-pentaoxo-3,6,9,12,18,24-hexazabicyclo[18.3.1]tetracosa-1(23),20(24),21-triene-13-carboxamide
Show/Hide
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C39H47N11O6
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1
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| 1 |
IC50 > 10000 nM
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CP0378446
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(4R,7S,10S,13S)-7-[3-(diaminomethylideneamino)propyl]-10-(1H-indol-3-ylmethyl)-4-(naphthalen-2-ylmethyl)-2,5,8,11,19-pentaoxo-3,6,9,12,18,24-hexazabicyclo[18.3.1]tetracosa-1(23),20(24),21-triene-13-carboxamide
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C43H49N11O6
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1
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| 1 |
IC50 > 10000 nM
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|
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CP0408820
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-23-methyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
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C80H109N23O17S2
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1
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| 1 |
IC50 = 11220.18 nM
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CP0396381
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-17,23-dimethyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
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C81H111N23O17S2
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1
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| 1 |
IC50 = 16218.1 nM
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CP0432642
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-14-methyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
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C80H109N23O17S2
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1
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| 1 |
IC50 = 25118.86 nM
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CP0432648
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-14,17,23-trimethyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
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C82H113N23O17S2
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1
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| 1 |
IC50 > 100000 nM
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CP0427899
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(7S,10R,13S,16S,19S)-10-benzyl-13-[3-(diaminomethylideneamino)propyl]-16-(1H-indol-3-ylmethyl)-2,8,11,14,17,25-hexaoxo-3,9,12,15,18,24-hexazatricyclo[24.4.0.03,7]triaconta-1(30),26,28-triene-19-carboxamide
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C45H55N11O7
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1
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| 1 |
IC50 > 1000 nM
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CP0407279
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C75H102N22O15
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1
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| 1 |
IC50 > 1000 nM
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CP0396380
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-14,17-dimethyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
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C81H111N23O17S2
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1
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| 1 |
IC50 > 1000 nM
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CP0408815
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-17-methyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
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C80H109N23O17S2
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1
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| 1 |
IC50 > 1000 nM
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CP0460800
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2-[(1R,4S,7S,13S,16S,19S,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
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C79H107N23O17S2
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1
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| 1 |
IC50 > 1000 nM
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CP0383564
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(8S,11S,14S,17R,20S)-17-benzyl-14-[3-(diaminomethylideneamino)propyl]-20-(1H-imidazol-5-ylmethyl)-11-(1H-indol-3-ylmethyl)-6,10,13,16,19,22-hexaoxo-5,9,12,15,18,21-hexazaspiro[3.18]docosane-8-carboxamide
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C41H51N13O7
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1
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| 1 |
IC50 > 1000 nM
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CP0383567
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(10S,13S,16S,19R,22S)-16-[3-(diaminomethylideneamino)propyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-19-(naphthalen-2-ylmethyl)-7,12,15,18,21,24-hexaoxo-6,11,14,17,20,23-hexazaspiro[4.19]tetracosane-10-carboxamide
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C47H57N13O7
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1
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| 1 |
IC50 > 1000 nM
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CP0404106
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(10S,13S,16S,19R,22S)-19-benzyl-16-[3-(diaminomethylideneamino)propyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-8,12,15,18,21,24-hexaoxo-7,11,14,17,20,23-hexazaspiro[5.18]tetracosane-10-carboxamide
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C43H55N13O7
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1
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| 1 |
IC50 > 1000 nM
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CP0576761
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-4,4,21,21-tetramethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.2.2]octacosa-1(26),24,27-triene-5-carboxamide
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C58H78N14O8S2
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1
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| 1 |
IC50 > 1000 nM
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CP0870114
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(3R,6R,9S,12R,15S)-12-benzyl-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-6-(1H-indol-3-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
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C42H47N13O8S
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1
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| 1 |
IC50 > 2000 nM
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CP0166249
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(4S)-5-[(2S)-1-[(2S)-1-[(2S)-1-[(2S)-1-[2-[(2S)-6-amino-1-[(2S)-2-[N-[(2S)-1-(carboxymethylimino)-1-hydroxy-3-methylbutan-2-yl]-C-hydroxycarbonimidoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]imino-2-hydroxyethyl]imino-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl]imino-5-carbamimidamido-1-hydroxypentan-2-yl]imino-1-hydroxy-3-phenylpropan-2-yl]imino-1-hydroxy-3-(1H-imidazol-5-yl)propan-2-yl]imino-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[[(2S)-1-[(2S)-2-[[(2S)-2-amino-1,4-dihydroxy-4-iminobutylidene]amino]-3-carboxypropanoyl]pyrrolidin-2-yl]-hydroxymethylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxy-3-(4-hydroxyphenyl)propylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxy-4-methylsulfanylbutylidene]amino]-5-hydroxypentanoic acid
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C90H127N25O26S
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1
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| 1 |
Ki = 0.17 nM
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CP0378500
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Ac-YRMEHdFRWGSPPKD-NH2
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C84H119N25O21S
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1
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| 1 |
Ki = 0.26 nM
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CP0456406
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(3S)-3-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-phenylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C77H103N21O15
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1
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| 1 |
Ki = 0.71 nM
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CP0395138
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(3S)-3-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C79H104N22O15
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1
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| 1 |
Ki = 0.76 nM
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CP0439884
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Ac-YRMEHdFRWG-NH2
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C61H83N19O13S
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1
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| 1 |
Ki = 0.84 nM
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CP0391680
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(3S)-3-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-6-(hex-5-ynoylamino)hexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C91H122N24O17
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1
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| 1 |
Ki = 1.4 nM
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CP0290684
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4-[((R)-N-Cyclohexyl-3-methyl-piperazine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
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C27H35Cl2N5O
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1
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| 1 |
Ki = 2.1 nM
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CP0391678
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(3S)-3-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-6-(hex-5-ynoylamino)hexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-phenylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C89H121N23O17
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1
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| 1 |
Ki = 3.9 nM
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CP0210565
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4-[N''-(2-Amino-2-methyl-propyl)-N''''-cyclohexyl-guanidino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
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C26H35Cl2N5O
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1
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| 1 |
Ki = 5.3 nM
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CP0149427
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4-[((S)-N-(R)-Cyclohexyl-2,5-dimethyl-piperazine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
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C28H37Cl2N5O
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1
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| 1 |
Ki = 5.9 nM
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CP0102543
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4-[(N-Cyclohexyl-3,5-dimethyl-piperazine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
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C28H37Cl2N5O
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1
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| 1 |
Ki = 11 nM
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CP0433388
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1-{2-[(1S)-(Methylaminoacetamido)-2-methylpropyl]-4-chlorophenyl}-4-[(2R)-methyl-3-(2-methoxy-4-dichlorophenyl)propionyl]piperazine
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C28H38Cl2N4O3
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1
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| 1 |
Ki = 13 nM
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CP0052754
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4-[(N-Cyclohexyl-piperazine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
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C26H33Cl2N5O
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1
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| 1 |
Ki = 18 nM
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CP0077679
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4-[((S)-N-Cyclohexyl-3-methyl-piperazine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
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C27H35Cl2N5O
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1
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| 1 |
Ki = 21 nM
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CP0378499
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(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-(2-aminoacetyl)pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[(2S)-2-[(2S)-2-[[(2S)-6-amino-1-[[(2S)-1-amino-3-carboxy-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
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C89H127N27O22S
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1
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| 1 |
Ki = 24.8 nM
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CP0278410
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4-(N''-Cyclohexyl-N''''-pyrrolidin-3-yl-guanidino)-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
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C26H33Cl2N5O
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1
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| 1 |
Ki = 26 nM
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CP0459213
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(2S)-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-5-(diaminomethylideneamino)-2-[[(2R)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(4-phenylbutanoylamino)propanoyl]amino]-3-phenylpropanoyl]amino]pentanamide
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C42H51N11O5
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1
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| 1 |
Ki = 27 nM
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CP0442623
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1-{2-[(1S)-((2R)-Aminopropionamido)-2-methylpropyl]-4-chlorophenyl}-4-[(2R)-methyl-3-(2-methoxy-4-dichlorophenyl)propionyl]piperazine
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C28H38Cl2N4O3
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1
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| 1 |
Ki = 34 nM
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CP0277007
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4-[(N-Cyclohexyl-3-methylamino-pyrrolidine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
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C27H35Cl2N5O
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1
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| 1 |
Ki = 36 nM
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CP0439875
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Ac-YR[CEH(d-2alpha-Nal)RWC]-NH2
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C64H81N19O13S2
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1
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| 1 |
Ki = 37.8 nM
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CP0439876
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Ac-YR[CEH(pCl-dF)RWC]-NH2
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C60H78ClN19O13S2
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1
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| 1 |
Ki = 42.19 nM
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CP0497385
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4-[(4-Benzyl-N-cyclohexyl-piperazine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
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C33H39Cl2N5O
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1
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| 1 |
Ki = 44 nM
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CP0393548
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(2S)-2-[[2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2R)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(4-phenylbutanoylamino)propanoyl]amino]-3-phenylpropanoyl]amino]pentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]acetyl]amino]-6-(hex-5-ynoylamino)hexanamide
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C56H72N14O8
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1
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| 1 |
Ki = 46 nM
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CP0466989
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4-[(N-Cyclohexyl-4-methyl-piperazine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
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C27H35Cl2N5O
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1
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| 1 |
Ki = 50 nM
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CP0391679
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(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-acetamido-4-phenylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-5-(diaminomethylideneamino)pentanamide
Show/Hide
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C44H54N12O6
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1
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| 1 |
Ki = 58 nM
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CP0464640
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Ac-YRC(Me)*EHdFRWC(Me)NH2
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C62H85N19O13S2
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1
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| 1 |
Ki = 62.11 nM
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CP0415759
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1-{2-[(1S)-(Methylaminoacetamido)-2-methylpropyl]-6-fluorophenyl}-4-[(2R)-methyl-3-(2-methoxy-4-chlorophenyl)propionyl]piperazine
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C28H38ClFN4O3
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1
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| 1 |
Ki = 67 nM
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CP0494627
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4-[N''-Cyclohexyl-N''''-(3,5-difluoro-benzyl)-guanidino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
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C29H30Cl2F2N4O
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1
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| 1 |
Ki = 70 nM
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CP0434327
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Beta MSH
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C118H174N34O35S
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1
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| 1 |
Ki = 76.9 nM
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CP0496767
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4-[(N-Cyclohexyl-4-pyrrolidin-1-yl-piperidine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
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C31H41Cl2N5O
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1
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| 1 |
Ki = 77 nM
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CP0376144
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(1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)propionyl]-1-piperazinyl}-5-(trifluoromethyl)phenyl]-3-methylbutylamine
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C27H35ClF3N3O2
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1
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| 1 |
Ki = 86 nM
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CP0404709
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N-[2-(2,4-dichlorophenyl)ethyl]-4-[(N,N'-dicyclohexyl-N-methylcarbamimidoyl)amino]benzamide
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C29H38Cl2N4O
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1
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| 1 |
Ki = 91 nM
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CP0442631
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1-{2-[(1S)-(Methylaminoacetamido)-2-methylpropyl]-4-chlorophenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine
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C27H36Cl2N4O2
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1
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| 1 |
Ki = 110 nM
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CP0565426
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4-[(N-Cyclohexyl-3,5-dimethyl-piperidine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
Show/Hide
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C29H38Cl2N4O
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1
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| 1 |
Ki = 144 nM
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CP0391662
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N-[(2R)-3-(2,4-dichlorophenyl)-1-oxo-1-[4-[2-[(2-thiophen-2-ylethylamino)methyl]phenyl]piperazin-1-yl]propan-2-yl]pyrrolidine-1-carboxamide
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C31H37Cl2N5O2S
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1
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| 1 |
Ki = 160 nM
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CP0395344
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3-amino-N-((1S)-1-(2-(4-(3-(2,4-dichlorophenyl)propanoyl)piperazin-1-yl)-5-(trifluoromethyl)phenyl)-2-methylbutyl)propanamide
Show/Hide
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C28H35Cl2F3N4O2
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1
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| 1 |
Ki = 170 nM
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CP0058986
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1-{2-[(1S)-(methylaminoacetamido)-2-methylpropyl]-4-methylphenyl}-4-[(2R)-methyl-3-(2-fluoro-4-chlorophenyl)propionyl]piperazine
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C28H38ClFN4O2
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1
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| 1 |
Ki = 180 nM
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CP0430022
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4-[(4-Amino-N-cyclohexyl-piperidine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
Show/Hide
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C27H35Cl2N5O
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1
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| 1 |
Ki = 230 nM
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CP0485105
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Ac-YR[CEH(pF-dF)RWC]-NH2
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C60H78FN19O13S2
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1
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| 1 |
Ki = 239.3 nM
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CP0234420
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(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-amide
Show/Hide
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C36H40ClN5O2S
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1
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| 1 |
Ki = 240 nM
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CP0373687
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1-{4-[(1R)-2-(amino-3-methylbutyl)-6-fluorophenyl]-4-[(2R)-(3-aminopropionylamido)-3-(2,4-dichlorophenyl)propionyl]}-piperazine
Show/Hide
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C27H36Cl2FN5O2
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1
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| 1 |
Ki = 240 nM
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CP0135959
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1-((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-(trifluoromethyl)phenyl)piperazin-1-yl)-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl)pyrrolidin-2-one
Show/Hide
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C29H35Cl2F3N4O2
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1
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| 1 |
Ki = 250 nM
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CP0437137
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1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-(2-{[2-(2-fluoro-phenyl)-ethylamino]-methyl}-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-amide
Show/Hide
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C38H41ClFN5O2
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1
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| 1 |
Ki = 260 nM
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CP0378145
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(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[1-(piperidin-3-ylamino)-ethyl]-phenyl}-piperazin-1-yl)-ethyl]-amide
Show/Hide
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C36H45ClN6O2
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1
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| 1 |
Ki = 270 nM
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CP0234419
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(R)-3-amino-N-(3-(2,4-dichlorophenyl)-1-oxo-1-(4-(2-((2-(thiophen-2-yl)ethylamino)methyl)phenyl)piperazin-1-yl)propan-2-yl)propanamide
Show/Hide
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C29H35Cl2N5O2S
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1
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| 1 |
Ki = 280 nM
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CP0501332
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4-[(N-Cyclohexyl-4-phenyl-piperazine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
Show/Hide
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C32H37Cl2N5O
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1
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| 1 |
Ki = 290 nM
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CP0059755
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1-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-3-ethyl-urea
Show/Hide
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C29H35Cl2N5O2S
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1
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| 1 |
Ki = 300 nM
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CP0497221
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4-[(N-Cyclohexyl-4-pyrimidin-2-yl-piperazine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
Show/Hide
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C30H35Cl2N7O
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1
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| 1 |
Ki = 305 nM
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CP0136197
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1-{2-[(1S)-(aminopropionyl)amino-2-methylpropyl]-4-methylphenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine
Show/Hide
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C28H39ClN4O2
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1
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| 1 |
Ki = 320 nM
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CP0296428
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1-{2-[(1S)-(methylaminopropionyl)amino-2-methylpropyl]-4-methylphenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine
Show/Hide
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C29H41ClN4O2
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1
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| 1 |
Ki = 340 nM
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CP0436667
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4-[(N-Cyclohexyl-2,6-dimethyl-morpholine-4-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
Show/Hide
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C28H36Cl2N4O2
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1
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| 1 |
Ki = 350 nM
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CP0279198
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1-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-3-(2-hydroxy-ethyl)-urea
Show/Hide
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C29H35Cl2N5O3S
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1
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| 1 |
Ki = 350 nM
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CP0382383
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3-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-1,1-dimethyl-urea
Show/Hide
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C29H35Cl2N5O2S
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1
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| 1 |
Ki = 350 nM
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CP0446682
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4-(N''''-Cyclohexyl-N'',N''-dipropyl-guanidino)-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
Show/Hide
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C28H38Cl2N4O
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1
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| 1 |
Ki = 360 nM
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CP0373690
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1-[(R)-2-{4-[(1S)-2-(1-amino-3-methylbutyl)-4-trifluoromethylphenyl]piperazin-1-yl}-1-(2,4-dichlorobenzyl)-2-oxoethyl]-piperazin-2-one
Show/Hide
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C29H36Cl2F3N5O2
|
1
|
| 1 |
Ki = 360 nM
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CP0386368
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1-{2-[(1S)-(3-Dimethylaminopropionamino)-2-methylpropyl]-4-chlorophenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine
Show/Hide
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C29H40Cl2N4O2
|
1
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| 1 |
Ki = 390 nM
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CP0503293
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1-{2-[(1S)-(1-Methyl-3-azetadinylcarbonyl)-amino-2-methylpropyl]-4-chlorophenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine
Show/Hide
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C29H38Cl2N4O2
|
1
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| 1 |
Ki = 400 nM
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CP0439032
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N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-(diethylamino)-1-(2-fluorophenyl)ethyl]piperazin-1-yl]-1-oxopropan-2-yl]-1,1-dimethyl-3,4-dihydro-2H-isoquinoline-3-carboxamide
Show/Hide
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C37H47ClFN5O2
|
1
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| 1 |
Ki = 420 nM
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CP0448705
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3-Amino-N-{(R)-1-(2,4-dichloro-benzyl)-2-[4-(1-{[2-(3-methoxy-phenyl)-acetylamino]-methyl}-cyclohexyl)-piperazin-1-yl]-2-oxo-ethyl}-propionamide
Show/Hide
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C32H43Cl2N5O4
|
1
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| 1 |
Ki = 470 nM
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CP0391936
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3-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-{1-[(2-thiophen-2-yl-acetylamino)-methyl]-cyclohexyl}-piperazin-1-yl)-ethyl]-propionamide
Show/Hide
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C29H39Cl2N5O3S
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1
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| 1 |
Ki = 480 nM
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CP0373165
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(S)-2-amino-N-(1-(2-(4-(3-(2,4-dichlorophenyl)propanoyl)piperazin-1-yl)-5-(trifluoromethyl)phenyl)-3-methylbutyl)acetamide
Show/Hide
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C27H33Cl2F3N4O2
|
1
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| 1 |
Ki = 500 nM
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CP0135976
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N-[(1S)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl]piperazin-1-yl]-5-methylphenyl]-3-methylbutyl]-3-(dimethylamino)propanamide
Show/Hide
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C34H47Cl2N5O3
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1
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| 1 |
Ki = 520 nM
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CP0422196
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(R)-3-amino-N-(3-(2,4-dichlorophenyl)-1-(4-(1-((2-(4-methoxyphenyl)acetamido)methyl)cyclohexyl)piperazin-1-yl)-1-oxopropan-2-yl)propanamide
Show/Hide
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C32H43Cl2N5O4
|
1
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| 1 |
Ki = 540 nM
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CP0404707
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4-[(N-Cyclohexyl-3-oxo-piperazine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
Show/Hide
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C26H31Cl2N5O2
|
1
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| 1 |
Ki = 560 nM
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CP0392260
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2-fluoroethyl N-[(2R)-3-(2,4-dichlorophenyl)-1-oxo-1-[4-[2-[(2-thiophen-2-ylethylamino)methyl]phenyl]piperazin-1-yl]propan-2-yl]carbamate
Show/Hide
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C29H33Cl2FN4O3S
|
1
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| 1 |
Ki = 560 nM
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CP0377910
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1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[1-((S)-pyrrolidin-3-ylamino)-ethyl]-phenyl}-piperazin-1-yl)-ethyl]-amide
Show/Hide
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C35H43ClN6O2
|
1
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| 1 |
Ki = 590 nM
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CP0050799
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N-[(1S)-1-[5-chloro-2-[4-[(2R)-3-(4-chlorophenyl)-2-methylpropanoyl]piperazin-1-yl]phenyl]-3-methylbutyl]-3-(dimethylamino)propanamide
Show/Hide
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C30H42Cl2N4O2
|
1
|
| 1 |
Ki = 600 nM
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CP0041099
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propan-2-yl N-[(2R)-3-(2,4-dichlorophenyl)-1-oxo-1-[4-[2-[(2-thiophen-2-ylethylamino)methyl]phenyl]piperazin-1-yl]propan-2-yl]carbamate
Show/Hide
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C30H36Cl2N4O3S
|
1
|
| 1 |
Ki = 680 nM
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CP0466190
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1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-(2-imidazol-1-ylmethyl-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-amide
Show/Hide
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C33H35ClN6O2
|
1
|
| 1 |
Ki = 700 nM
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CP0378345
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N-[(1S)-1-[2-[4-[(2R)-3-(4-chlorophenyl)-2-methylpropanoyl]piperazin-1-yl]-5-methylphenyl]-3-methylbutyl]-3-(dimethylamino)propanamide
Show/Hide
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C31H45ClN4O2
|
1
|
| 1 |
Ki = 710 nM
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CP0430024
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N-[(2R)-3-(4-chlorophenyl)-1-oxo-1-[4-[2-[(2-thiophen-2-ylethylamino)methyl]phenyl]piperazin-1-yl]propan-2-yl]piperidine-3-carboxamide
Show/Hide
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C32H40ClN5O2S
|
1
|
| 1 |
Ki = 720 nM
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CP0403268
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N-[(2R)-3-(4-chlorophenyl)-1-oxo-1-[4-[2-[(2-thiophen-2-ylethylamino)methyl]phenyl]piperazin-1-yl]propan-2-yl]pyridine-3-carboxamide
Show/Hide
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C32H34ClN5O2S
|
1
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| 1 |
Ki = 730 nM
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CP0050225
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(R)-N-(3-(2,4-dichlorophenyl)-1-oxo-1-(4-(2-((2-(thiophen-2-yl)ethylamino)methyl)phenyl)piperazin-1-yl)propan-2-yl)acetamide
Show/Hide
|
C28H32Cl2N4O2S
|
1
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| 1 |
Ki = 730 nM
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CP0197235
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1-((R)-1-(4-(2-((S)-1-(2-aminoethylamino)-3-methylbutyl)-6-fluorophenyl)piperazin-1-yl)-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl)pyrrolidin-2-one
Show/Hide
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C30H40Cl2FN5O2
|
1
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| 1 |
Ki = 850 nM
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CP0424915
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N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-(diethylamino)-1-(2-fluorophenyl)ethyl]piperazin-1-yl]-1-oxopropan-2-yl]-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)acetamide
Show/Hide
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C36H45ClFN5O2
|
1
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| 1 |
Ki = 910 nM
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CP0486406
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3-Amino-N-((R)-1-(2,4-dichloro-benzyl)-2-oxo-2-{4-[1-(phenylacetylamino-methyl)-cyclohexyl]-piperazin-1-yl}-ethyl)-propionamide
Show/Hide
|
C31H41Cl2N5O3
|
1
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| 1 |
Ki = 920 nM
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CP0424914
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N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-(diethylamino)-1-(2-fluorophenyl)ethyl]piperazin-1-yl]-1-oxopropan-2-yl]isoquinoline-3-carboxamide
Show/Hide
|
C35H39ClFN5O2
|
1
|
| 1 |
Ki = 920 nM
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CP0424911
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(R)-N-((R)-3-(4-chlorophenyl)-1-(4-(2-(diethylamino)-1-(2-fluorophenyl)ethyl)piperazin-1-yl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
Show/Hide
|
C35H43ClFN5O2
|
1
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| 1 |
Ki = 950 nM
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CP0425108
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-(2R)-[2-aminoacetamido]-3-(4-chlorophenyl)propionyl-1-2-[(2-thienyl)ethylaminomethyl]phenyl piperazine
Show/Hide
|
C28H34ClN5O2S
|
1
|
| 1 |
Ki = 990 nM
|
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CP0296277
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1-[(R)-2-{4-[2-((S)-1-amino-3-methylbutyl)-4-trifluoromethylphenyl]-piperazin-1-yl}-1-(4-dichlorobenzyl)-2-oxoethyl]pyrrolidin-2-one
Show/Hide
|
C29H36ClF3N4O2
|
1
|
| 1 |
Ki = 990 nM
|
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CP0399948
|
3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-propionamide
Show/Hide
|
C29H36ClN5O2S
|
1
|
| 1 |
Ki = 1000 nM
|
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CP0442321
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4-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-butyramide
Show/Hide
|
C30H38ClN5O2S
|
1
|
| 1 |
Ki = 1000 nM
|
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CP0453047
|
(1S)-(2-{4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]-1-piperazinyl}-5-methylphenyl)-3-methylbutylamine
Show/Hide
|
C26H36ClN3O
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
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CP0509848
|
4-[(N-Cyclohexyl-2-methyl-3-oxo-piperazine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
Show/Hide
|
C27H33Cl2N5O2
|
1
|
| 1 |
Ki = 1050 nM
|
|
|
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CP0173276
|
1-{2-[(1S)-(3-Dimethylaminopropionamino)-2-methylpropyl]-6-fluorophenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine
Show/Hide
|
C29H40ClFN4O2
|
1
|
| 1 |
Ki = 1100 nM
|
|
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CP0415761
|
1-{2-[(1S)-(Methylaminoacetamido)-2-methylpropyl]-6-fluorophenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine
Show/Hide
|
C27H36ClFN4O2
|
1
|
| 1 |
Ki = 1100 nM
|
|
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CP0393003
|
N-[(1R)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-methylpropanoyl]piperazin-1-yl]-6-methylpyridin-3-yl]-3-methylbutyl]-3-(dimethylamino)propanamide
Show/Hide
|
C30H43Cl2N5O2
|
1
|
| 1 |
Ki = 1200 nM
|
|
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CP0449030
|
3-Amino-N-((R)-1-(2,4-dichloro-benzyl)-2-oxo-2-{4-[1-(phenethylamino-methyl)-cyclohexyl]-piperazin-1-yl}-ethyl)-propionamide
Show/Hide
|
C31H43Cl2N5O2
|
1
|
| 1 |
Ki = 1200 nM
|
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CP0432776
|
N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-(diethylamino)-1-(2-fluorophenyl)ethyl]piperazin-1-yl]-1-oxopropan-2-yl]-2-(2,3-dihydro-1H-isoindol-1-yl)acetamide
Show/Hide
|
C35H43ClFN5O2
|
1
|
| 1 |
Ki = 1200 nM
|
|
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CP0370229
|
(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-(2-methanesulfonylamino-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-amide
Show/Hide
|
C30H34ClN5O4S
|
1
|
| 1 |
Ki = 1200 nM
|
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|
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CP0394376
|
(S)-1-(4-(2-(1-amino-3-methylbutyl)-6-fluorophenyl)piperazin-1-yl)-3-(2,4-dichlorophenyl)propan-1-one
Show/Hide
|
C24H30Cl2FN3O
|
1
|
| 1 |
Ki = 1200 nM
|
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CP0058988
|
1-{2-[(1S)-(3-dimethylaminopropionyl)amino-2-methylpropyl]-4-methylphenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine
Show/Hide
|
C30H43ClN4O2
|
1
|
| 1 |
Ki = 1200 nM
|
|
|
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CP0391594
|
3-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-(4-{1-[(2-fluoro-benzylamino)-methyl]-cyclohexyl}-piperazin-1-yl)-2-oxo-ethyl]-propionamide
Show/Hide
|
C30H40Cl2FN5O2
|
1
|
| 1 |
Ki = 1400 nM
|
|
|
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CP0424913
|
N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-(diethylamino)-1-(2-fluorophenyl)ethyl]piperazin-1-yl]-1-oxopropan-2-yl]-2-(1-methyl-2,3-dihydroisoindol-1-yl)acetamide
Show/Hide
|
C36H45ClFN5O2
|
1
|
| 1 |
Ki = 1400 nM
|
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CP0460887
|
(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-(2-dimethylaminomethyl-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-amide
Show/Hide
|
C32H38ClN5O2
|
1
|
| 1 |
Ki = 1400 nM
|
|
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CP0506580
|
4-{[N-Cyclohexyl-4-(2,5-dimethyl-phenyl)-piperazine-1-carboximidoyl]-amino}-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
Show/Hide
|
C34H41Cl2N5O
|
1
|
| 1 |
Ki = 1760 nM
|
|
|
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CP0378182
|
3-Amino-N-{(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-[4-(1-{[(thiophen-2-ylmethyl)-amino]-methyl}-cyclohexyl)-piperazin-1-yl]-ethyl}-propionamide
Show/Hide
|
C28H39Cl2N5O2S
|
1
|
| 1 |
Ki = 1900 nM
|
|
|
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CP0500013
|
N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-(diethylamino)-1-(2-fluorophenyl)ethyl]piperazin-1-yl]-1-oxopropan-2-yl]-2-(2-methyl-1,3-dihydroisoindol-1-yl)acetamide
Show/Hide
|
C36H45ClFN5O2
|
1
|
| 1 |
Ki = 2000 nM
|
|
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CP0496016
|
(R)-N-(1-(4-(3-((2-methoxyphenethylamino)methyl)pyridin-2-yl)piperazin-1-yl)-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl)-3-aminopropanamide
Show/Hide
|
C31H38Cl2N6O3
|
1
|
| 1 |
Ki = 2100 nM
|
|
|
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CP0160526
|
(R)-N-((R)-1-(4-(2-(aminomethyl)phenyl)piperazin-1-yl)-3-(4-chlorophenyl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
Show/Hide
|
C30H34ClN5O2
|
1
|
| 1 |
Ki = 2300 nM
|
|
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CP0523759
|
1-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-3-(2-fluoro-benzyl)-urea
Show/Hide
|
C34H36Cl2FN5O2S
|
1
|
| 1 |
Ki = 2300 nM
|
|
|
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CP0185382
|
Ac-dR[CEHdFRWC]-NH2
Show/Hide
|
C51H70N18O11S2
|
1
|
| 1 |
Ki > 500 nM
|
|
|
|
CP0276967
|
Ac-YR[CEHdFRWC]-NH2
Show/Hide
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C60H79N19O13S2
|
1
|
| 1 |
Ki > 500 nM
|
|
|
|
CP0403125
|
Ac-YCit[CEHdFRWC]-NH2
Show/Hide
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C60H78N18O14S2
|
1
|
| 1 |
Ki > 500 nM
|
|
|
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CP0436210
|
Ac-YR[CE(1-Me-H)dFRWC]-NH2
Show/Hide
|
C61H81N19O13S2
|
1
|
| 1 |
Ki > 500 nM
|
|
|
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CP0485106
|
Ac-[CEHdFRWC]-NH2
Show/Hide
|
C45H58N14O10S2
|
1
|
| 1 |
Ki > 500 nM
|
|
|
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CP0486686
|
Ac-YK[CEHdFRWC]-NH2
Show/Hide
|
C60H79N17O13S2
|
1
|
| 1 |
Ki > 500 nM
|
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|
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CP0486687
|
Ac-R[CEHdFRWC]-NH2
Show/Hide
|
C51H70N18O11S2
|
1
|
| 1 |
Ki > 500 nM
|
|
|
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CP0847736
|
Ac-YR[CEHdFRWC]SPPKD-NH2
Show/Hide
|
C83H115N25O21S2
|
1
|
| 1 |
Ki > 500 nM
|
|
|
|
CP0877876
|
Ac-YR[CEHFRWC]-NH2
Show/Hide
|
C60H79N19O13S2
|
1
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| 1 |
Ki > 500 nM
|
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