General Information of the Compound
Compound ID
CP0446682
Compound Name
4-(N''''-Cyclohexyl-N'',N''-dipropyl-guanidino)-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
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Structure
Formula
C28H38Cl2N4O
Molecular Weight
517.545
Canonical SMILES
CCCN(CCC)C(Nc1ccc(cc1)C(=O)NCCc1ccc(Cl)cc1Cl)=NC1CCCCC1
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InChI
InChI=1S/C28H38Cl2N4O/c1-3-18-34(19-4-2)28(32-24-8-6-5-7-9-24)33-25-14-11-22(12-15-25)27(35)31-17-16-21-10-13-23(29)20-26(21)30/h10-15,20,24H,3-9,16-19H2,1-2H3,(H,31,35)(H,32,33)
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InChIKey
JVEDQEAAHLSYLV-UHFFFAOYSA-N
Physicochemical Property
logP
7.1885
Rotatable Bonds
10
Heavy Atom Count
35
Polar Areas
56.73
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11443753
SID: 16541992
ChEMBL ID
CHEMBL186189
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01804, Melanocortin receptor 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 360 nM
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