General Information of the Compound
Compound ID
CP0501332
Compound Name
4-[(N-Cyclohexyl-4-phenyl-piperazine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide
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Structure
Formula
C32H37Cl2N5O
Molecular Weight
578.588
Canonical SMILES
Clc1ccc(CCNC(=O)c2ccc(NC(=NC3CCCCC3)N3CCN(CC3)c3ccccc3)cc2)c(Cl)c1
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InChI
InChI=1S/C32H37Cl2N5O/c33-26-14-11-24(30(34)23-26)17-18-35-31(40)25-12-15-28(16-13-25)37-32(36-27-7-3-1-4-8-27)39-21-19-38(20-22-39)29-9-5-2-6-10-29/h2,5-6,9-16,23,27H,1,3-4,7-8,17-22H2,(H,35,40)(H,36,37)
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InChIKey
XMUPUYAWRNUGJZ-UHFFFAOYSA-N
Physicochemical Property
logP
6.8887
Rotatable Bonds
7
Heavy Atom Count
40
Polar Areas
59.97
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11192466
SID: 16273482
ChEMBL ID
CHEMBL183842
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01804, Melanocortin receptor 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 290 nM
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