| Compound ID |
Compound Name |
Compound Formula |
|
CP0507590
|
(R)-4-propyl-6,6a,7,8,9,10-hexahydro-5H- pyrazino[1,2-a][1,8]naphthyridine
Show/Hide
|
C14H21N3
|
2
|
| 1 |
EC50 = 0.0631 nM
|
|
|
| 2 |
Ki = 0.1585 nM
|
|
|
|
CP0001238
|
14C-5-hydroxy tryptamine creatinine disulfate
Show/Hide
|
C10H12N2O
|
7
|
| 1 |
EC50 = 0.09 nM
|
|
|
| 2 |
EC50 = 0.21 nM
|
|
|
| 3 |
EC50 = 0.41 nM
|
|
|
| 4 |
EC50 = 25.12 nM
|
|
|
| 5 |
EC50 = 190.55 nM
|
|
|
| 6 |
Ki = 20 nM
|
|
|
| 7 |
Ki = 50.12 nM
|
|
|
|
CP0537707
|
(6aR)-4-(cyclobutylmethyl)-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,8]naphthyridine
Show/Hide
|
C16H23N3
|
3
|
| 1 |
EC50 = 0.1 nM
|
|
|
| 2 |
EC50 = 0.108 nM
|
|
|
| 3 |
Ki = 0.5012 nM
|
|
|
|
CP0417178
|
(6aR)-4-benzyl-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,8]naphthyridine
Show/Hide
|
C18H21N3
|
3
|
| 1 |
EC50 = 0.116 nM
|
|
|
| 2 |
EC50 = 0.1259 nM
|
|
|
| 3 |
Ki = 0.2512 nM
|
|
|
|
CP0514110
|
(6aR)-4-[(3-fluorophenyl)methyl]-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,8]naphthyridine
Show/Hide
|
C18H20FN3
|
1
|
| 1 |
EC50 = 0.19 nM
|
|
|
|
CP0446727
|
7-propyl-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C15H22N2
|
2
|
| 1 |
EC50 = 0.1995 nM
|
|
|
| 2 |
Ki = 0.3981 nM
|
|
|
|
CP0507589
|
(4aR)-7-propyl-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C15H22N2
|
2
|
| 1 |
EC50 = 0.1995 nM
|
|
|
| 2 |
Ki = 0.3162 nM
|
|
|
|
CP0451827
|
7-ethylsulfanyl-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C14H20N2S
|
1
|
| 1 |
EC50 = 0.3162 nM
|
|
|
|
CP0037955
|
METHIOTHEPIN
Show/Hide
|
C20H24N2S2
|
1
|
| 1 |
EC50 = 0.38 nM
|
|
|
|
CP0546024
|
(R)-4-isobutyl-6,6a,7,8,9,10-hexahydro-5H- pyrazino[1,2-a][1,8]naphthyridine
Show/Hide
|
C15H23N3
|
2
|
| 1 |
EC50 = 0.3981 nM
|
|
|
| 2 |
Ki = 0.631 nM
|
|
|
|
CP0557803
|
(R)-4-benzyl-6,6a,7,8,9,10-hexahydro-5H- pyrazino[1,2-a][1,7]naphthyridine
Show/Hide
|
C18H21N3
|
2
|
| 1 |
EC50 = 0.631 nM
|
|
|
| 2 |
Ki = 0.5012 nM
|
|
|
|
CP0700642
|
(+)-(S,S)-trans-[2-(2-Bromophenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H13BrClN
|
1
|
| 1 |
EC50 = 0.78 nM
|
|
|
|
CP0376945
|
9-fluoro-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C12H15FN2
|
1
|
| 1 |
EC50 = 0.7943 nM
|
|
|
|
CP0446725
|
7-(thiophen-2-ylmethyl)-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C17H20N2S
|
2
|
| 1 |
EC50 = 0.7943 nM
|
|
|
| 2 |
Ki = 0.3162 nM
|
|
|
|
CP0408278
|
7-benzyl-8-fluoro-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C19H21FN2
|
2
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
Ki = 0.3981 nM
|
|
|
|
CP0417175
|
(6aR)-4-cyclobutyl-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,8]naphthyridine
Show/Hide
|
C15H21N3
|
1
|
| 1 |
EC50 = 1.14 nM
|
|
|
|
CP0507588
|
(6aR)-4-propyl-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,7]naphthyridine
Show/Hide
|
C14H21N3
|
3
|
| 1 |
EC50 = 1.17 nM
|
|
|
| 2 |
EC50 = 1.259 nM
|
|
|
| 3 |
Ki = 1.995 nM
|
|
|
|
CP0472831
|
(6aR)-4-(3,3,3-trifluoropropyl)-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,8]naphthyridine
Show/Hide
|
C14H18F3N3
|
3
|
| 1 |
EC50 = 1.259 nM
|
|
|
| 2 |
EC50 = 1.33 nM
|
|
|
| 3 |
Ki = 1.585 nM
|
|
|
|
CP0784795
|
trans-[2-(2-Bromophenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H13BrClN
|
1
|
| 1 |
EC50 = 1.3 nM
|
|
|
|
CP0376979
|
7-benzyl-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C19H22N2
|
2
|
| 1 |
EC50 = 1.585 nM
|
|
|
| 2 |
Ki = 0.631 nM
|
|
|
|
CP0376977
|
7-methyl-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C13H18N2
|
1
|
| 1 |
EC50 = 1.995 nM
|
|
|
|
CP0507586
|
(R)-4-methyl-6,6a,7,8,9,10-hexahydro-5H- pyrazino[1,2-a][1,8]naphthyridine
Show/Hide
|
C12H17N3
|
1
|
| 1 |
EC50 = 1.995 nM
|
|
|
|
CP0464654
|
8-Iodo-7-methoxy-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C12H16INO
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0465092
|
8-(1-ethyl-5-pyridazin-3-ylpyrazol-3-yl)quinoline
Show/Hide
|
C18H15N5
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0380003
|
1-(2-Naphthyl)-2-aminopropane
Show/Hide
|
C13H15N
|
1
|
| 1 |
EC50 = 2.3 nM
|
|
|
|
CP0408308
|
(4aR)-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C12H16N2
|
1
|
| 1 |
EC50 = 2.512 nM
|
|
|
|
CP0912053
|
2-Benzyl-N-(4-fluorophenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
|
C21H22ClFN4
|
1
|
| 1 |
EC50 = 2.6 nM
|
|
|
|
CP0071447
|
(1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
Show/Hide
|
C11H14ClN
|
6
|
| 1 |
EC50 = 2.7 nM
|
|
|
| 2 |
EC50 = 3.6 nM
|
|
|
| 3 |
EC50 = 7.943 nM
|
|
|
| 4 |
EC50 = 9 nM
|
|
|
| 5 |
EC50 = 11 nM
|
|
|
| 6 |
Ki = 15 nM
|
|
|
|
CP0390974
|
(1S)-8,9-dichloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
Show/Hide
|
C11H13Cl2N
|
2
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
EC50 = 3.162 nM
|
|
|
|
CP0394842
|
8-Bromo-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol
Show/Hide
|
C11H14BrNO
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0404837
|
(R)-8-Bromo-7-methoxy-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C12H16BrNO
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0700641
|
trans-[2-(2-Chloro-4-fluorophenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H12Cl2FN
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0376981
|
7-(cyclobutylmethyl)-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C17H24N2
|
2
|
| 1 |
EC50 = 3.162 nM
|
|
|
| 2 |
Ki = 0.631 nM
|
|
|
|
CP0408303
|
7-cyclobutyl-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C16H22N2
|
1
|
| 1 |
EC50 = 3.162 nM
|
|
|
|
CP0446724
|
8-fluoro-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C12H15FN2
|
1
|
| 1 |
EC50 = 3.162 nM
|
|
|
|
CP0537711
|
(4aR)-7-(3,3,3-trifluoropropyl)-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C15H19F3N2
|
2
|
| 1 |
EC50 = 3.162 nM
|
|
|
| 2 |
Ki = 1.995 nM
|
|
|
|
CP0849289
|
trans-[2-(3-Fluorophenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H13ClFN
|
1
|
| 1 |
EC50 = 3.3 nM
|
|
|
|
CP0849290
|
trans-[2-(3-Hydroxyphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H14ClNO
|
1
|
| 1 |
EC50 = 3.3 nM
|
|
|
|
CP0086043
|
[(1S,2S)-2-[5-fluoro-2-(2-fluoroethoxy)phenyl]cyclopropyl]methanamine;hydrochloride
Show/Hide
|
C12H16ClF2NO
|
1
|
| 1 |
EC50 = 3.4 nM
|
|
|
|
CP0845430
|
trans-[2-(2-Chloro-6-methylphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C11H15Cl2N
|
1
|
| 1 |
EC50 = 3.5 nM
|
|
|
|
CP0193993
|
(S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine
Show/Hide
|
C11H12ClFN2
|
1
|
| 1 |
EC50 = 3.981 nM
|
|
|
|
CP0378395
|
(1R,S)-7,8-dichloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
Show/Hide
|
C11H13Cl2N
|
2
|
| 1 |
EC50 = 3.981 nM
|
|
|
| 2 |
EC50 = 4 nM
|
|
|
|
CP0412393
|
(5R)-7,8-dichloro-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
Show/Hide
|
C11H13Cl2N
|
1
|
| 1 |
EC50 = 3.981 nM
|
|
|
|
CP0458390
|
(5S)-7-chloro-6-fluoro-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
Show/Hide
|
C11H13ClFN
|
1
|
| 1 |
EC50 = 3.981 nM
|
|
|
|
CP0542436
|
(5aR)-9-chloro-10-methoxy-1,2,3,4,5,5a,6,7-octahydro-[1,4]diazepino[1,2-a]quinoline
Show/Hide
|
C14H19ClN2O
|
1
|
| 1 |
EC50 = 3.981 nM
|
|
|
|
CP0486871
|
7-Methoxy-1-methyl-8-trifluoromethyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C13H16F3NO
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0177271
|
[(1S,2S)-2-(5-fluoro-2-prop-2-enoxyphenyl)cyclopropyl]methanamine;hydrochloride
Show/Hide
|
C13H17ClFNO
|
1
|
| 1 |
EC50 = 4.2 nM
|
|
|
|
CP0647970
|
trans-[2-(3-Methylphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C11H16ClN
|
1
|
| 1 |
EC50 = 4.8 nM
|
|
|
|
CP0377370
|
8-Bromo-7-methoxy-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C12H16BrNO
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0433577
|
(S)-8-Bromo-7-methoxy-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C12H16BrNO
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0413012
|
6-(2-ethyl-5-quinolin-8-ylpyrazol-3-yl)pyridazin-3-amine
Show/Hide
|
C18H16N6
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0507587
|
(R)-4-(methoxymethyl)-6,6a,7,8,9,10-hexahydro- 5H-pyrazino[1,2-a][1,8]naphthyridine
Show/Hide
|
C13H19N3O
|
2
|
| 1 |
EC50 = 5.012 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
|
CP0558632
|
(6aR)-4-chloro-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,8]naphthyridine
Show/Hide
|
C11H14ClN3
|
1
|
| 1 |
EC50 = 5.012 nM
|
|
|
|
CP0900679
|
trans-[2-(2-Chlorophenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H13Cl2N
|
1
|
| 1 |
EC50 = 5.1 nM
|
|
|
|
CP0880097
|
(+)-trans-(S,S)-(2-Phenylcyclopropyl)methylamine Hydrochloride
Show/Hide
|
C10H14ClN
|
1
|
| 1 |
EC50 = 5.2 nM
|
|
|
|
CP0700640
|
trans-[2-(4-Fluorophenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H13ClFN
|
1
|
| 1 |
EC50 = 5.4 nM
|
|
|
|
CP0417177
|
(6aR)-4-(2,2-dimethylpropyl)-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,8]naphthyridine
Show/Hide
|
C16H25N3
|
1
|
| 1 |
EC50 = 5.84 nM
|
|
|
|
CP0454131
|
(1R,S)-8,9-dichloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
Show/Hide
|
C11H13Cl2N
|
2
|
| 1 |
EC50 = 6 nM
|
|
|
| 2 |
EC50 = 7.943 nM
|
|
|
|
CP0870099
|
trans-[2-(4-Fluoro-3-methylphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C11H15ClFN
|
1
|
| 1 |
EC50 = 6 nM
|
|
|
|
CP0327501
|
[4-(hydroxymethyl)piperidin-1-yl]-(4-methyl-2-naphthalen-1-yl-1,3-thiazol-5-yl)methanone
Show/Hide
|
C21H22N2O2S
|
1
|
| 1 |
EC50 = 6 nM
|
|
|
|
CP0387276
|
[4-(hydroxymethyl)piperidin-1-yl]-(2-methyl-5-naphthalen-1-ylpyrazol-3-yl)methanone
Show/Hide
|
C21H23N3O2
|
1
|
| 1 |
EC50 = 6 nM
|
|
|
|
CP0430209
|
(1R,S)-8-chloro-7-fluoro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
Show/Hide
|
C11H13ClFN
|
2
|
| 1 |
EC50 = 6.31 nM
|
|
|
| 2 |
EC50 = 7 nM
|
|
|
|
CP0457653
|
(1R,S)-8-trifluoromethyl-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
Show/Hide
|
C12H14F3N
|
2
|
| 1 |
EC50 = 6.31 nM
|
|
|
| 2 |
EC50 = 7 nM
|
|
|
|
CP0513875
|
(5S)-7-chloro-8-methoxy-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
Show/Hide
|
C12H16ClNO
|
1
|
| 1 |
EC50 = 6.31 nM
|
|
|
|
CP0376950
|
10-chloro-9-fluoro-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C12H14ClFN2
|
1
|
| 1 |
EC50 = 6.31 nM
|
|
|
|
CP0408280
|
7-(1,3-benzodioxol-5-ylmethyl)-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C20H22N2O2
|
2
|
| 1 |
EC50 = 6.31 nM
|
|
|
| 2 |
Ki = 0.7943 nM
|
|
|
|
CP0558629
|
(6aR)-4-cyclopropyl-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,8]naphthyridine
Show/Hide
|
C14H19N3
|
1
|
| 1 |
EC50 = 6.31 nM
|
|
|
|
CP0852202
|
trans-[2-(2,3-Dimethylphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C12H18ClN
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0552352
|
6-(2-ethyl-5-isoquinolin-8-ylpyrazol-3-yl)pyridazin-3-amine
Show/Hide
|
C18H16N6
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0417179
|
(6aR)-4-[(4-fluorophenyl)methyl]-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,8]naphthyridine
Show/Hide
|
C18H20FN3
|
1
|
| 1 |
EC50 = 7.5 nM
|
|
|
|
CP0046618
|
1-(3-chlorophenyl)piperazine
Show/Hide
|
C10H13ClN2
|
5
|
| 1 |
EC50 = 7.943 nM
|
|
|
| 2 |
EC50 = 8.1 nM
|
|
|
| 3 |
EC50 = 12.59 nM
|
|
|
| 4 |
EC50 = 15 nM
|
|
|
| 5 |
Ki = 7.943 nM
|
|
|
|
CP0393037
|
(5R)-5-methyl-7-(trifluoromethyl)-2,3,4,5-tetrahydro-1H-3-benzazepine
Show/Hide
|
C12H14F3N
|
1
|
| 1 |
EC50 = 7.943 nM
|
|
|
|
CP0441710
|
(1R,S)-8-chloro-7-methoxy-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
Show/Hide
|
C12H16ClNO
|
2
|
| 1 |
EC50 = 7.943 nM
|
|
|
| 2 |
EC50 = 11 nM
|
|
|
|
CP0456699
|
(5S)-7,8-dichloro-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
Show/Hide
|
C11H13Cl2N
|
1
|
| 1 |
EC50 = 7.943 nM
|
|
|
|
CP0505009
|
(5R)-7-chloro-8-methoxy-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
Show/Hide
|
C12H16ClNO
|
1
|
| 1 |
EC50 = 7.943 nM
|
|
|
|
CP0505099
|
7-Bromo-8-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C11H14BrNO
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0870083
|
trans-[2-(3,4-Difluorophenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H12ClF2N
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0673446
|
2-Benzyl-N-(3-methoxyphenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
|
C22H25ClN4O
|
1
|
| 1 |
EC50 = 9.2 nM
|
|
|
|
CP0377365
|
8-Bromo-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C11H14BrN
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
EC50 = 12 nM
|
|
|
|
CP0456700
|
(5S)-5-methyl-7-(trifluoromethyl)-2,3,4,5-tetrahydro-1H-3-benzazepine
Show/Hide
|
C12H14F3N
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0849285
|
trans-[2-(3-Chlorophenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H13Cl2N
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0451824
|
(5aR)-10,11-dichloro-9-methoxy-1,2,3,4,5,5a,6,7-octahydro-[1,4]diazepino[1,2-a]quinoline
Show/Hide
|
C14H18Cl2N2O
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0394848
|
8-Bromo-1-ethyl-7-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C13H18BrNO
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0433579
|
(1R,S)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
Show/Hide
|
C11H14ClN
|
2
|
| 1 |
EC50 = 11 nM
|
|
|
| 2 |
EC50 = 12.59 nM
|
|
|
|
CP0882891
|
trans-[2-(2,3-Dichlorophenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H12Cl3N
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0859084
|
(+)-((1S,2S)-2-(5-fluoro-2-propoxyphenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C13H19ClFNO
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0436474
|
7-Chloro-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C10H12ClN
|
2
|
| 1 |
EC50 = 12 nM
|
|
|
| 2 |
EC50 = 12.59 nM
|
|
|
|
CP0517759
|
[4-(hydroxymethyl)piperidin-1-yl]-(2-methyl-5-naphthalen-1-yl-1H-pyrrol-3-yl)methanone
Show/Hide
|
C22H24N2O2
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0521785
|
N,4-dimethyl-2-naphthalen-1-yl-N-(pyridin-3-ylmethyl)-1,3-thiazole-5-carboxamide
Show/Hide
|
C22H19N3OS
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0417176
|
4-(cyclobutylmethyl)-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,8]naphthyridine
Show/Hide
|
C16H23N3
|
1
|
| 1 |
EC50 = 12.3 nM
|
|
|
|
CP0840284
|
trans-(2-Phenylcyclopropyl)methylamine Hydrochloride
Show/Hide
|
C10H14ClN
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0852203
|
trans-[2-(6-Chloro-2-fluoro-3-methylphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C11H14Cl2FN
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0859080
|
(+)-((1S,2S)-2-(5-chloro-2-ethoxyphenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C12H17Cl2NO
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0468762
|
N,4-dimethyl-N-[(1-methylpyrazol-3-yl)methyl]-2-naphthalen-1-yl-1,3-thiazole-5-carboxamide
Show/Hide
|
C21H20N4OS
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0548536
|
8-(1-ethyl-5-pyridazin-3-ylpyrazol-3-yl)isoquinoline
Show/Hide
|
C18H15N5
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0930544
|
trans-[2-(3-Bromophenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H13BrClN
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0393968
|
N-(2-methoxyethyl)-N,4-dimethyl-2-naphthalen-1-yl-1,3-thiazole-5-carboxamide
Show/Hide
|
C19H20N2O2S
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0472729
|
3-(2-ethyl-5-naphthalen-1-ylpyrazol-3-yl)pyridazine
Show/Hide
|
C19H16N4
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0377362
|
(1S)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
Show/Hide
|
C11H14ClN
|
2
|
| 1 |
EC50 = 15.85 nM
|
|
|
| 2 |
EC50 = 16 nM
|
|
|
|
CP0896360
|
trans-[2-(3-Methoxyphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C11H16ClNO
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0413009
|
[4-(hydroxymethyl)piperidin-1-yl]-(3-methyl-1-naphthalen-1-ylpyrazol-4-yl)methanone
Show/Hide
|
C21H23N3O2
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0548538
|
(4-hydroxyazepan-1-yl)-(4-methyl-2-naphthalen-1-yl-1,3-thiazol-5-yl)methanone
Show/Hide
|
C21H22N2O2S
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0859659
|
trans-[2-(2,4-Dichlorophenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H12Cl3N
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
|
CP0873758
|
rac-trans-[2-(2-Ethyloxyphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C12H18ClNO
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
|
CP0533875
|
[4-(2,3-dichlorophenyl)-1,3-thiazol-2-yl]-morpholin-4-ylmethanone
Show/Hide
|
C14H12Cl2N2O2S
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
|
CP0378396
|
(1R,S)-8-chloro-9-fluoro-2,3,4,5-tetrahydro-1-methyl-1H-3-
Show/Hide
|
C11H13ClFN
|
2
|
| 1 |
EC50 = 19.95 nM
|
|
|
| 2 |
EC50 = 22 nM
|
|
|
|
CP0390952
|
(1R,S)-6,8-dichloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
Show/Hide
|
C11H13Cl2N
|
2
|
| 1 |
EC50 = 19.95 nM
|
|
|
| 2 |
EC50 = 20 nM
|
|
|
|
CP0412390
|
(5S)-7-chloro-5-ethyl-2,3,4,5-tetrahydro-1H-3-benzazepine
Show/Hide
|
C12H16ClN
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0408304
|
(5aR)-8-benzyl-9-fluoro-1,2,3,4,5,5a,6,7-octahydro-[1,4]diazepino[1,2-a]quinoline
Show/Hide
|
C20H23FN2
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0446762
|
7-(methoxymethyl)-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C14H20N2O
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0458175
|
7-cyclobutyloxy-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C16H22N2O
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0458675
|
8-propyl-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C15H22N2
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0413007
|
[4-(hydroxymethyl)piperidin-1-yl]-(3-methyl-5-naphthalen-1-ylthiophen-2-yl)methanone
Show/Hide
|
C22H23NO2S
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0724162
|
2-Benzyl-N-phenyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
|
C21H23ClN4
|
1
|
| 1 |
EC50 = 20.1 nM
|
|
|
|
CP0450007
|
[(1S,2S)-2-[2-(cyclopropylmethoxy)-5-fluorophenyl]cyclopropyl]methanamine
Show/Hide
|
C14H18FNO
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
|
CP0446024
|
(2S,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimidin-2-yl)-octahydropyrrolo[3,4-b]pyrrole
Show/Hide
|
C12H15F3N4
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
|
CP0441921
|
[(1S,2S)-2-[5-fluoro-2-(2-fluoroprop-2-enoxy)phenyl]cyclopropyl]methanamine;hydrochloride
Show/Hide
|
C13H16ClF2NO
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
|
CP0403278
|
(3aS,6aS)-1-(4-(trifluoromethyl)pyrimidin-2-yl)-octahydropyrrolo[3,4-b]pyrrole
Show/Hide
|
C11H13F3N4
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
|
CP0893306
|
trans-[2-(2-Methylphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C11H16ClN
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
|
CP0873759
|
rac-trans-[2-(2-Propyloxyphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C13H20ClNO
|
1
|
| 1 |
EC50 = 24 nM
|
|
|
|
CP0387279
|
(4-methyl-2-naphthalen-1-yl-1,3-thiazol-5-yl)-piperidin-1-ylmethanone
Show/Hide
|
C20H20N2OS
|
1
|
| 1 |
EC50 = 24 nM
|
|
|
|
CP0413010
|
3-(2-methyl-5-naphthalen-1-ylpyrazol-3-yl)pyridazine
Show/Hide
|
C18H14N4
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0674236
|
2-Benzyl-N-(3-chlorophenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
|
C21H22Cl2N4
|
1
|
| 1 |
EC50 = 25.1 nM
|
|
|
|
CP0376059
|
(1R,S)-7-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
Show/Hide
|
C11H14ClN
|
2
|
| 1 |
EC50 = 25.12 nM
|
|
|
| 2 |
EC50 = 35 nM
|
|
|
|
CP0393033
|
Nor-d-fenfluramine
Show/Hide
|
C10H12F3N
|
1
|
| 1 |
EC50 = 25.12 nM
|
|
|
|
CP0408306
|
3-chloro-1,13-diazatricyclo[8.6.0.02,7]hexadeca-2(7),3,5-triene
Show/Hide
|
C14H19ClN2
|
1
|
| 1 |
EC50 = 25.12 nM
|
|
|
|
CP0466987
|
(5aR)-9-fluoro-1,2,3,4,5,5a,6,7-octahydro-[1,4]diazepino[1,2-a]quinoline
Show/Hide
|
C13H17FN2
|
1
|
| 1 |
EC50 = 25.12 nM
|
|
|
|
CP0850274
|
trans-[2-(2-Methoxyphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C11H16ClNO
|
1
|
| 1 |
EC50 = 26 nM
|
|
|
|
CP0456441
|
1-ethyl-5-(1-methylimidazol-2-yl)-3-naphthalen-1-ylpyrazole
Show/Hide
|
C19H18N4
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
|
CP0394843
|
8-Bromo-7-ethoxy-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C13H18BrNO
|
1
|
| 1 |
EC50 = 28 nM
|
|
|
|
CP0914908
|
trans-[2-(2-Fluorophenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H13ClFN
|
1
|
| 1 |
EC50 = 29 nM
|
|
|
|
CP0900678
|
trans-[2-(3-Trifluoromethylphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C11H13ClF3N
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0534768
|
N-(2-hydroxyethyl)-N,4-dimethyl-2-naphthalen-1-yl-1,3-thiazole-5-carboxamide
Show/Hide
|
C18H18N2O2S
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0376949
|
(5aR)-11-methoxy-1,2,3,4,5,5a,6,7-octahydro-[1,4]diazepino[1,2-a]quinoline
Show/Hide
|
C14H20N2O
|
1
|
| 1 |
EC50 = 31.62 nM
|
|
|
|
CP0724214
|
(+)-((1S,2S)-2-(5-chloro-2-(2-fluoroethoxy)phenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C12H16Cl2FNO
|
1
|
| 1 |
EC50 = 32 nM
|
|
|
|
CP0252379
|
2-(4-bromo-2,5-dimethoxyphenyl)-N-(2,3-dihydro-1-benzofuran-7-ylmethyl)ethanamine
Show/Hide
|
C19H22BrNO3
|
1
|
| 1 |
EC50 = 32.36 nM
|
|
|
|
CP0472830
|
(6aR)-4-bromo-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,8]naphthyridine
Show/Hide
|
C11H14BrN3
|
1
|
| 1 |
EC50 = 33.6 nM
|
|
|
|
CP0870100
|
trans-[2-(3,4-Dimethylphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C12H18ClN
|
1
|
| 1 |
EC50 = 35 nM
|
|
|
|
CP0456447
|
N,4-dimethyl-2-naphthalen-1-yl-N-(2-pyridin-3-ylethyl)-1,3-thiazole-5-carboxamide
Show/Hide
|
C23H21N3OS
|
1
|
| 1 |
EC50 = 38 nM
|
|
|
|
CP0412391
|
(5R)-7-chloro-5-ethyl-2,3,4,5-tetrahydro-1H-3-benzazepine
Show/Hide
|
C12H16ClN
|
1
|
| 1 |
EC50 = 39.81 nM
|
|
|
|
CP0446760
|
(5aR)-10-chloro-9-methoxy-1,2,3,4,5,5a,6,7-octahydro-[1,4]diazepino[1,2-a]quinoline
Show/Hide
|
C14H19ClN2O
|
1
|
| 1 |
EC50 = 39.81 nM
|
|
|
|
CP0413008
|
[4-(hydroxymethyl)piperidin-1-yl]-(1-methyl-4-naphthalen-1-ylpyrrol-2-yl)methanone
Show/Hide
|
C22H24N2O2
|
1
|
| 1 |
EC50 = 41 nM
|
|
|
|
CP0870098
|
trans-[2-(2,4-Difluorophenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H12ClF2N
|
1
|
| 1 |
EC50 = 42 nM
|
|
|
|
CP0412990
|
(4-methyl-2-naphthalen-1-yl-1,3-thiazol-5-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C20H21N3OS
|
1
|
| 1 |
EC50 = 43 nM
|
|
|
|
CP0055945
|
1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine
Show/Hide
|
C11H16INO2
|
1
|
| 1 |
EC50 = 45.71 nM
|
|
|
|
CP0463341
|
[4-(hydroxymethyl)piperidin-1-yl]-(2-methyl-5-naphthalen-1-ylthiophen-3-yl)methanone
Show/Hide
|
C22H23NO2S
|
1
|
| 1 |
EC50 = 47 nM
|
|
|
|
CP0517758
|
(4-hydroxypiperidin-1-yl)-(4-methyl-2-naphthalen-1-yl-1,3-thiazol-5-yl)methanone
Show/Hide
|
C20H20N2O2S
|
1
|
| 1 |
EC50 = 47 nM
|
|
|
|
CP0900680
|
trans-[2-(2-Trifluoromethylphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C11H13ClF3N
|
1
|
| 1 |
EC50 = 49 nM
|
|
|
|
CP0528050
|
8-chloro-7-methoxy-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
Show/Hide
|
C12H16ClNO
|
1
|
| 1 |
EC50 = 50.12 nM
|
|
|
|
CP0394206
|
7-Benzyloxy-8-bromo-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C18H20BrNO
|
1
|
| 1 |
EC50 = 56 nM
|
|
|
|
CP0451884
|
(2R,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimidin-2-yl)-octahydropyrrolo[3,4-b]pyrrole
Show/Hide
|
C12H15F3N4
|
1
|
| 1 |
EC50 = 57 nM
|
|
|
|
CP0387277
|
1-methyl-5-(1-methylimidazol-2-yl)-3-naphthalen-1-ylpyrazole
Show/Hide
|
C18H16N4
|
1
|
| 1 |
EC50 = 58 nM
|
|
|
|
CP0548046
|
N,N,4-trimethyl-2-naphthalen-1-yl-1,3-thiazole-5-carboxamide
Show/Hide
|
C17H16N2OS
|
1
|
| 1 |
EC50 = 59 nM
|
|
|
|
CP0720028
|
(+)-((1S,2S)-2-(2-(allyloxy)-5-chlorophenyl)cyclopropyl)methanamine trifluoroacetate
Show/Hide
|
C15H17ClF3NO3
|
1
|
| 1 |
EC50 = 60 nM
|
|
|
|
CP0859086
|
(+)-((1S,2S)-2-(5-chloro-2-(prop-2-ynyloxy)phenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C13H15Cl2NO
|
1
|
| 1 |
EC50 = 63 nM
|
|
|
|
CP0548542
|
[4-(hydroxymethyl)piperidin-1-yl]-(4-methyl-2-naphthalen-1-yl-1,3-oxazol-5-yl)methanone
Show/Hide
|
C21H22N2O3
|
1
|
| 1 |
EC50 = 63 nM
|
|
|
|
CP0458677
|
10-methyl-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C13H18N2
|
1
|
| 1 |
EC50 = 63.1 nM
|
|
|
|
CP0458679
|
(10R)-1,13-diazatricyclo[8.6.0.02,7]hexadeca-2,4,6-triene
Show/Hide
|
C14H20N2
|
1
|
| 1 |
EC50 = 63.1 nM
|
|
|
|
CP0466988
|
9-propyl-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C15H22N2
|
1
|
| 1 |
EC50 = 63.1 nM
|
|
|
|
CP0404865
|
8-Bromo-7-isopropoxy-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C14H20BrNO
|
1
|
| 1 |
EC50 = 68 nM
|
|
|
|
CP0517755
|
(4-methyl-2-naphthalen-1-yl-1,3-thiazol-5-yl)-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)methanone
Show/Hide
|
C21H18N4OS
|
1
|
| 1 |
EC50 = 68 nM
|
|
|
|
CP0849286
|
trans-[2-(4-Chlorophenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H13Cl2N
|
1
|
| 1 |
EC50 = 76 nM
|
|
|
|
CP0880104
|
(-)-(R,R)-trans-[2-(2-Methylphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H13BrClN
|
1
|
| 1 |
EC50 = 78 nM
|
|
|
|
CP0408307
|
(5aR)-10-methoxy-1,2,3,4,5,5a,6,7-octahydro-[1,4]diazepino[1,2-a]quinoline
Show/Hide
|
C14H20N2O
|
1
|
| 1 |
EC50 = 79.43 nM
|
|
|
|
CP0849287
|
trans-[2-(2,6-Difluorophenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H12ClF2N
|
1
|
| 1 |
EC50 = 87 nM
|
|
|
|
CP0859083
|
(+)-((1S,2S)-2-(5-chloro-2-(2,2-difluoroethoxy)phenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C12H15Cl2F2NO
|
1
|
| 1 |
EC50 = 91 nM
|
|
|
|
CP0859085
|
(+)-((1S,2S)-2-(5-chloro-2-isopropoxyphenyl)cyclopropyl)methanamine trifluoroacetate
Show/Hide
|
C15H19ClF3NO3
|
1
|
| 1 |
EC50 = 91 nM
|
|
|
|
CP0390023
|
(6aR)-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,8]naphthyridine
Show/Hide
|
C11H15N3
|
2
|
| 1 |
EC50 = 93.4 nM
|
|
|
| 2 |
EC50 = 100 nM
|
|
|
|
CP0547137
|
(4-methyl-2-naphthalen-1-yl-1,3-thiazol-5-yl)-morpholin-4-ylmethanone
Show/Hide
|
C19H18N2O2S
|
1
|
| 1 |
EC50 = 95 nM
|
|
|
|
CP0850281
|
trans-[2-(2-Bromo-4-methylphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C11H15BrClN
|
1
|
| 1 |
EC50 = 97 nM
|
|
|
|
CP0891443
|
trans-[2-(2,3-Difluorophenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H12ClF2N
|
1
|
| 1 |
EC50 = 99 nM
|
|
|
|
CP0458159
|
7-phenoxy-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C18H20N2O
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0442317
|
(3aS,6aS)-1-(3-(trifluoromethyl)phenyl)-octahydropyrrolo[3,4-b]pyrrole
Show/Hide
|
C13H15F3N2
|
1
|
| 1 |
EC50 = 103 nM
|
|
|
|
CP0857297
|
(+)-((1S,2S)-2-(5-chloro-2-propoxyphenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C13H19Cl2NO
|
1
|
| 1 |
EC50 = 103 nM
|
|
|
|
CP0521789
|
[2-(2,3-dichlorophenyl)-1,3-thiazol-4-yl]-morpholin-4-ylmethanone
Show/Hide
|
C14H12Cl2N2O2S
|
1
|
| 1 |
EC50 = 119 nM
|
|
|
|
CP0376978
|
7-phenyl-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C18H20N2
|
1
|
| 1 |
EC50 = 125.89 nM
|
|
|
|
CP0458676
|
8-(cyclobutylmethyl)-1,2,3,4,5,5a,6,7-octahydro-[1,4]diazepino[1,2-a]quinoline
Show/Hide
|
C18H26N2
|
1
|
| 1 |
EC50 = 125.89 nM
|
|
|
|
CP0849291
|
trans-[2-(4-Chloro-2-fluorophenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H12Cl2FN
|
1
|
| 1 |
EC50 = 128 nM
|
|
|
|
CP0548528
|
[2-(2,3-dichlorophenyl)-1,3-thiazol-4-yl]-(2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)methanone
Show/Hide
|
C15H12Cl2N2O2S
|
1
|
| 1 |
EC50 = 129 nM
|
|
|
|
CP0782210
|
(+)-((1S,2S)-2-(5-chloro-2-(2-fluoroallyloxy)phenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C13H16Cl2FNO
|
1
|
| 1 |
EC50 = 133 nM
|
|
|
|
CP0845429
|
trans-[2-(4-Methylphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C11H16ClN
|
1
|
| 1 |
EC50 = 135 nM
|
|
|
|
CP0912297
|
trans-[2-(3-Ethynylphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C12H14ClN
|
1
|
| 1 |
EC50 = 136 nM
|
|
|
|
CP0870003
|
trans-[2-(4-Bromophenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H13BrClN
|
1
|
| 1 |
EC50 = 138 nM
|
|
|
|
CP0400568
|
[(1R,2R)-2-(5-fluoro-2-prop-2-enoxyphenyl)cyclopropyl]methanamine;hydrochloride
Show/Hide
|
C13H17ClFNO
|
1
|
| 1 |
EC50 = 157 nM
|
|
|
|
CP0446761
|
(5aR)-11-chloro-10-methoxy-1,2,3,4,5,5a,6,7-octahydro-[1,4]diazepino[1,2-a]quinoline
Show/Hide
|
C14H19ClN2O
|
1
|
| 1 |
EC50 = 158.49 nM
|
|
|
|
CP0500592
|
8-Bromo-1-isopropyl-7-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C14H20BrNO
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0904513
|
trans-[2-(2-Hydroxyphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C10H14ClNO
|
1
|
| 1 |
EC50 = 161 nM
|
|
|
|
CP0453704
|
1-[4-(trifluoromethyl)pyrimidin-2-yl]-3,3a,4,5,6,6a-hexahydro-2H-pyrrolo[2,3-c]pyrrole
Show/Hide
|
C11H13F3N4
|
1
|
| 1 |
EC50 = 180 nM
|
|
|
|
CP0514755
|
[(1S,2S)-2-[5-chloro-2-(2-methoxyethoxy)phenyl]cyclopropyl]methanamine;hydrochloride
Show/Hide
|
C13H19Cl2NO2
|
1
|
| 1 |
EC50 = 183 nM
|
|
|
|
CP0521786
|
5-(2-ethyl-5-naphthalen-1-ylpyrazol-3-yl)-1-methyl-1,2,4-triazole
Show/Hide
|
C18H17N5
|
1
|
| 1 |
EC50 = 190 nM
|
|
|
|
CP0390950
|
8-Methoxy-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C12H17NO
|
2
|
| 1 |
EC50 = 199.53 nM
|
|
|
| 2 |
EC50 = 420 nM
|
|
|
|
CP0412369
|
7-chloro-5,5-dimethyl-1,2,3,4-tetrahydro-3-benzazepine
Show/Hide
|
C12H16ClN
|
1
|
| 1 |
EC50 = 199.53 nM
|
|
|
|
CP0376973
|
5-chloro-1,13-diazatricyclo[8.6.0.02,7]hexadeca-2(7),3,5-triene
Show/Hide
|
C14H19ClN2
|
1
|
| 1 |
EC50 = 199.53 nM
|
|
|
|
CP0866925
|
(+)-((1S,2S)-2-(5-chloro-2-(3-fluoropropoxy)phenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C13H18Cl2FNO
|
1
|
| 1 |
EC50 = 206 nM
|
|
|
|
CP0865273
|
(+)-((1S,2S)-2-(5-chloro-2-(2-methylallyloxy)phenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C14H19Cl2NO
|
1
|
| 1 |
EC50 = 212 nM
|
|
|
|
CP0377363
|
(1R)-8,9-dichloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
Show/Hide
|
C11H13Cl2N
|
2
|
| 1 |
EC50 = 230 nM
|
|
|
| 2 |
EC50 = 316.23 nM
|
|
|
|
CP0880098
|
trans-{2-[2-(6-Hydroxyhex-1-ynyl)phenyl]cyclopropyl}methylamine Hydrochloride
Show/Hide
|
C16H22ClNO
|
1
|
| 1 |
EC50 = 232 nM
|
|
|
|
CP0449614
|
[(1S,2S)-2-[5-chloro-2-(2-methylsulfanylethoxy)phenyl]cyclopropyl]methanamine;hydrochloride
Show/Hide
|
C13H19Cl2NOS
|
1
|
| 1 |
EC50 = 244 nM
|
|
|
|
CP0912333
|
(+)-((1S,2S)-2-(5-chloro-2-(cyclopropylmethoxy)phenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C14H19Cl2NO
|
1
|
| 1 |
EC50 = 251 nM
|
|
|
|
CP0408277
|
8-methoxy-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline
Show/Hide
|
C13H18N2O
|
1
|
| 1 |
EC50 = 251.19 nM
|
|
|
|
CP0864140
|
rac-trans-[2-(2-Isobutyloxyphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C14H22ClNO
|
1
|
| 1 |
EC50 = 254 nM
|
|
|
|
CP0040203
|
1,2,3,4,8,9,10,11-octahydro-[1,4]diazepino[6,7,1-jk]carbazole
Show/Hide
|
C15H18N2
|
1
|
| 1 |
EC50 = 261 nM
|
|
|
|
CP0709872
|
2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-fluoro-3-methoxybenzyl)ethanamine
Show/Hide
|
C18H21BrFNO3
|
1
|
| 1 |
EC50 = 281.84 nM
|
|
|
|
CP0514754
|
[(1S,2S)-2-(2-butoxy-5-chlorophenyl)cyclopropyl]methanamine;2,2,2-trifluoroacetic acid
Show/Hide
|
C16H21ClF3NO3
|
1
|
| 1 |
EC50 = 288 nM
|
|
|
|
CP0387280
|
1-(1-ethyl-5-pyridazin-3-ylpyrazol-3-yl)isoquinoline
Show/Hide
|
C18H15N5
|
1
|
| 1 |
EC50 = 291 nM
|
|
|
|
CP0908183
|
(-)-((1R,2R)-2-(5-fluoro-2-propoxyphenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C13H19ClFNO
|
1
|
| 1 |
EC50 = 296 nM
|
|
|
|
CP0852027
|
trans-[2-(4'-Fluorobiphenyl-2-yl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C16H17ClFN
|
1
|
| 1 |
EC50 = 301 nM
|
|
|
|
CP0873389
|
rac-trans-[2-(2-Benzyloxyphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C17H20ClNO
|
1
|
| 1 |
EC50 = 304 nM
|
|
|
|
CP0413011
|
4-(1-ethyl-5-pyridazin-3-ylpyrazol-3-yl)quinoline
Show/Hide
|
C18H15N5
|
1
|
| 1 |
EC50 = 315 nM
|
|
|
|
CP0404853
|
1-Methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C11H15N
|
2
|
| 1 |
EC50 = 316.23 nM
|
|
|
| 2 |
EC50 = 340 nM
|
|
|
|
CP0412956
|
(6aR)-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,7]naphthyridine
Show/Hide
|
C11H15N3
|
2
|
| 1 |
EC50 = 316.23 nM
|
|
|
| 2 |
EC50 = 329 nM
|
|
|
|
CP0449727
|
(3aS,6aS)-1-(3-fluorophenyl)-octahydropyrrolo[3,4-b]pyrrole
Show/Hide
|
C12H15FN2
|
1
|
| 1 |
EC50 = 319 nM
|
|
|
|
CP0552340
|
[2-(2,3-dichlorophenyl)-1,3-thiazol-4-yl]-(1,4-oxazepan-4-yl)methanone
Show/Hide
|
C15H14Cl2N2O2S
|
1
|
| 1 |
EC50 = 320 nM
|
|
|
|
CP0913387
|
trans-{2-[3-(6-Hydroxyhex-1-ynyl)phenyl]cyclopropyl}methylamine Hydrochloride
Show/Hide
|
C16H22ClNO
|
1
|
| 1 |
EC50 = 332 nM
|
|
|
|
CP0519929
|
[4-(hydroxymethyl)piperidin-1-yl]-(5-methyl-2-naphthalen-1-yltriazol-4-yl)methanone
Show/Hide
|
C20H22N4O2
|
1
|
| 1 |
EC50 = 334 nM
|
|
|
|
CP0930396
|
(-)-((1R,2R)-2-(5-chloro-2-(prop-2-ynyloxy)phenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C13H15Cl2NO
|
1
|
| 1 |
EC50 = 365 nM
|
|
|
|
CP0476136
|
[4-(hydroxymethyl)piperidin-1-yl]-(4-methyl-1-naphthalen-1-ylpyrrol-3-yl)methanone
Show/Hide
|
C22H24N2O2
|
1
|
| 1 |
EC50 = 369 nM
|
|
|
|
CP0387274
|
[4-(hydroxymethyl)piperidin-1-yl]-(5-methyl-2-naphthalen-1-yl-1,3-oxazol-4-yl)methanone
Show/Hide
|
C21H22N2O3
|
1
|
| 1 |
EC50 = 381 nM
|
|
|
|
CP0376060
|
(1R,S)-8-fluoro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
Show/Hide
|
C11H14FN
|
2
|
| 1 |
EC50 = 398.11 nM
|
|
|
| 2 |
EC50 = 410 nM
|
|
|
|
CP0503364
|
(3aS,4S,6aR)-4-(3-(trifluoromethyl)phenyl)-octahydrocyclopenta[c]pyrrole
Show/Hide
|
C14H16F3N
|
1
|
| 1 |
EC50 = 420 nM
|
|
|
|
CP0456448
|
5-(2-ethyl-5-naphthalen-1-ylpyrazol-3-yl)-1-methyltetrazole
Show/Hide
|
C17H16N6
|
1
|
| 1 |
EC50 = 450 nM
|
|
|
|
CP0521790
|
[2-(2,3-dimethylphenyl)-1,3-thiazol-4-yl]-morpholin-4-ylmethanone
Show/Hide
|
C16H18N2O2S
|
1
|
| 1 |
EC50 = 501 nM
|
|
|
|
CP0465148
|
(3aS,6aS)-1-(3-chlorophenyl)-octahydropyrrolo[3,4-b]pyrrole
Show/Hide
|
C12H15ClN2
|
1
|
| 1 |
EC50 = 503 nM
|
|
|
|
CP0453824
|
[(1R,2R)-2-[5-fluoro-2-(2-fluoroethoxy)phenyl]cyclopropyl]methanamine;hydrochloride
Show/Hide
|
C12H16ClF2NO
|
1
|
| 1 |
EC50 = 514 nM
|
|
|
|
CP0453702
|
(3aR,6aR)-1-(4-(trifluoromethyl)pyrimidin-2-yl)-octahydropyrrolo[3,4-b]pyrrole
Show/Hide
|
C11H13F3N4
|
1
|
| 1 |
EC50 = 519 nM
|
|
|
|
CP0460500
|
4-(1-ethyl-5-pyridazin-3-ylpyrazol-3-yl)isoquinoline
Show/Hide
|
C18H15N5
|
1
|
| 1 |
EC50 = 530 nM
|
|
|
|
CP0521787
|
2-(2-ethyl-5-naphthalen-1-ylpyrazol-3-yl)pyridine
Show/Hide
|
C20H17N3
|
1
|
| 1 |
EC50 = 576 nM
|
|
|
|
CP0376976
|
(5aR)-9-methoxy-1,2,3,4,5,5a,6,7-octahydro-[1,4]diazepino[1,2-a]quinoline
Show/Hide
|
C14H20N2O
|
1
|
| 1 |
EC50 = 630.96 nM
|
|
|
|
CP0374099
|
N-methyl-1-[(1S,2S)-2-phenylcyclopropyl]methanamine
Show/Hide
|
C11H15N
|
1
|
| 1 |
EC50 = 634 nM
|
|
|
|
CP0912315
|
(-)-((1R,2R)-2-(5-chloro-2-ethoxyphenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C12H17Cl2NO
|
1
|
| 1 |
EC50 = 646 nM
|
|
|
|
CP0859082
|
(-)-((1R,2R)-2-(5-chloro-2-(2-methoxyethoxy)phenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C13H19Cl2NO2
|
1
|
| 1 |
EC50 = 667 nM
|
|
|
|
CP0517756
|
[2-(2,3-dichlorophenyl)-1,3-thiazol-4-yl]-(4-hydroxypiperidin-1-yl)methanone
Show/Hide
|
C15H14Cl2N2O2S
|
1
|
| 1 |
EC50 = 679 nM
|
|
|
|
CP0512568
|
[(1R,2R)-2-(2-butoxy-5-chlorophenyl)cyclopropyl]methanamine;2,2,2-trifluoroacetic acid
Show/Hide
|
C16H21ClF3NO3
|
1
|
| 1 |
EC50 = 683 nM
|
|
|
|
CP0916695
|
trans-[2-(4'-Fluorobiphenyl-3-yl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C16H17ClFN
|
1
|
| 1 |
EC50 = 695 nM
|
|
|
|
CP0387272
|
morpholin-4-yl-(4-naphthalen-1-yl-1,3-thiazol-2-yl)methanone
Show/Hide
|
C18H16N2O2S
|
1
|
| 1 |
EC50 = 729 nM
|
|
|
|
CP0864187
|
(-)-((1R,2R)-2-(2-(allyloxy)-5-chlorophenyl)cyclopropyl)methanamine trifluoroacetate
Show/Hide
|
C15H17ClF3NO3
|
1
|
| 1 |
EC50 = 737 nM
|
|
|
|
CP0384469
|
N-[4-[[(1S,2S)-2-(2,3-dichlorophenyl)cyclopropyl]methyl-propylamino]butyl]-4-pyridin-2-ylbenzamide;hydrochloride
Show/Hide
|
C29H34Cl3N3O
|
1
|
| 1 |
EC50 = 738.3 nM
|
|
|
|
CP0387278
|
morpholin-4-yl-(2-naphthalen-1-yl-1,3-thiazol-4-yl)methanone
Show/Hide
|
C18H16N2O2S
|
1
|
| 1 |
EC50 = 766 nM
|
|
|
|
CP0900681
|
trans-[2-(4-Trifluoromethylphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C11H13ClF3N
|
1
|
| 1 |
EC50 = 779 nM
|
|
|
|
CP0377364
|
(1R,S)-9-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
Show/Hide
|
C11H14ClN
|
2
|
| 1 |
EC50 = 794.33 nM
|
|
|
| 2 |
EC50 = 930 nM
|
|
|
|
CP0412392
|
(1R,S)-6-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
Show/Hide
|
C11H14ClN
|
2
|
| 1 |
EC50 = 794.33 nM
|
|
|
| 2 |
EC50 = 860 nM
|
|
|
|
CP0900683
|
trans-[2-(4-Methoxyphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C11H16ClNO
|
1
|
| 1 |
EC50 = 902 nM
|
|
|
|
CP0845422
|
(-)-trans-(R,R)-(2-Phenylcyclopropyl)methylamine Hydrochloride
Show/Hide
|
C10H14ClN
|
1
|
| 1 |
EC50 = 909 nM
|
|
|
|
CP0857295
|
(-)-((1R,2R)-2-(5-chloro-2-(2,2-difluoroethoxy)phenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C12H15Cl2F2NO
|
1
|
| 1 |
EC50 = 914 nM
|
|
|
|
CP0859043
|
(-)-trans-(R,R)-[2-(2-Cyclopropylmethyloxyphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C14H20ClNO
|
1
|
| 1 |
EC50 = 978 nM
|
|
|
|
CP0488216
|
[(1R,2R)-2-[5-fluoro-2-(2-fluoroprop-2-enoxy)phenyl]cyclopropyl]methanamine;hydrochloride
Show/Hide
|
C13H16ClF2NO
|
1
|
| 1 |
EC50 = 985 nM
|
|
|
|
CP0452058
|
(5aR)-8-methoxy-1,2,3,4,5,5a,6,7-octahydro-[1,4]diazepino[1,2-a]quinoline
Show/Hide
|
C14H20N2O
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0521046
|
[4-(hydroxymethyl)piperidin-1-yl]-(3-methyl-5-naphthalen-1-ylfuran-2-yl)methanone
Show/Hide
|
C22H23NO3
|
1
|
| 1 |
EC50 = 1032 nM
|
|
|
|
CP0521784
|
(4-methyl-2-naphthalen-1-yl-1,3-thiazol-5-yl)-piperazin-1-ylmethanone
Show/Hide
|
C19H19N3OS
|
1
|
| 1 |
EC50 = 1040 nM
|
|
|
|
CP0859081
|
(-)-((1R,2R)-2-(5-chloro-2-(cyclopropylmethoxy)phenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C14H19Cl2NO
|
1
|
| 1 |
EC50 = 1082 nM
|
|
|
|
CP0889545
|
(-)-((1R,2R)-2-(5-chloro-2-(2-fluoroethoxy)phenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C12H16Cl2FNO
|
1
|
| 1 |
EC50 = 1127 nM
|
|
|
|
CP0851157
|
trans-[3-(2-Aminomethylcyclopropyl)phenyl]benzylamine Hydrochloride
Show/Hide
|
C17H21ClN2
|
1
|
| 1 |
EC50 = 1179 nM
|
|
|
|
CP0845433
|
trans-[2-(4-Furan-2-ylphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C14H16ClNO
|
1
|
| 1 |
EC50 = 1196 nM
|
|
|
|
CP0856416
|
N,N-Dimethyl-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine hydrochloride
Show/Hide
|
C15H27ClN6
|
1
|
| 1 |
EC50 = 1200 nM
|
|
|
|
CP0859042
|
rac-trans-(2-(2-(cyclobutylmethoxy)phenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C15H22ClNO
|
1
|
| 1 |
EC50 = 1210 nM
|
|
|
|
CP0906298
|
(-)-((1R,2R)-2-(5-chloro-2-propoxyphenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C13H19Cl2NO
|
1
|
| 1 |
EC50 = 1228 nM
|
|
|
|
CP0857299
|
(-)-((1R,2R)-2-(5-chloro-2-(3-fluoropropoxy)phenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C13H18Cl2FNO
|
1
|
| 1 |
EC50 = 1258 nM
|
|
|
|
CP0394197
|
7-methoxy-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C12H17NO
|
2
|
| 1 |
EC50 = 1258.93 nM
|
|
|
| 2 |
EC50 = 2000 nM
|
|
|
|
CP0466991
|
6,6-dimethyl-1,2,3,4,4a,5-hexahydropyrazino[1,2-a]quinoline
Show/Hide
|
C14H20N2
|
1
|
| 1 |
EC50 = 1258.93 nM
|
|
|
|
CP0413005
|
[2-(3-chloro-2-fluorophenyl)-1,3-thiazol-4-yl]-morpholin-4-ylmethanone
Show/Hide
|
C14H12ClFN2O2S
|
1
|
| 1 |
EC50 = 1272 nM
|
|
|
|
CP0857950
|
N-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine hydrochloride
Show/Hide
|
C19H26ClFN6
|
1
|
| 1 |
EC50 = 1500 nM
|
|
|
|
CP0456442
|
[2-(2,3-dichlorophenyl)-5-methyl-1,3-thiazol-4-yl]-morpholin-4-ylmethanone
Show/Hide
|
C15H14Cl2N2O2S
|
1
|
| 1 |
EC50 = 1520 nM
|
|
|
|
CP0413001
|
morpholin-4-yl-(2-naphthalen-1-yl-1,3-thiazol-5-yl)methanone
Show/Hide
|
C18H16N2O2S
|
1
|
| 1 |
EC50 = 1522 nM
|
|
|
|
CP0851156
|
trans-[2-(4'-Chlorobiphenyl-3-yl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C16H17Cl2N
|
1
|
| 1 |
EC50 = 1577 nM
|
|
|
|
CP0413004
|
5-(1-ethyl-5-pyridazin-3-ylpyrazol-3-yl)isoquinoline
Show/Hide
|
C18H15N5
|
1
|
| 1 |
EC50 = 1600 nM
|
|
|
|
CP0465091
|
2-(2-ethyl-5-naphthalen-1-ylpyrazol-3-yl)pyrimidine
Show/Hide
|
C19H16N4
|
1
|
| 1 |
EC50 = 1697 nM
|
|
|
|
CP0400563
|
[(1R,2R)-2-[5-chloro-2-(2-methylsulfanylethoxy)phenyl]cyclopropyl]methanamine;hydrochloride
Show/Hide
|
C13H19Cl2NOS
|
1
|
| 1 |
EC50 = 1762 nM
|
|
|
|
CP0387275
|
[4-(hydroxymethyl)piperidin-1-yl]-(1-methyl-4-naphthalen-1-ylimidazol-2-yl)methanone
Show/Hide
|
C21H23N3O2
|
1
|
| 1 |
EC50 = 1804 nM
|
|
|
|
CP0460501
|
(3,5-dimethyl-2-naphthalen-1-ylimidazol-4-yl)-[4-(hydroxymethyl)piperidin-1-yl]methanone
Show/Hide
|
C22H25N3O2
|
1
|
| 1 |
EC50 = 1870 nM
|
|
|
|
CP0880106
|
trans-C-[2-(2-Benzofuran-2-ylphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C18H18ClNO
|
1
|
| 1 |
EC50 = 1965 nM
|
|
|
|
CP0859044
|
rac-trans-C-[2-(4'-Fluoro-4-methoxy-biphenyl-3-yl)-cyclopropyl]-methylamine Hydrochloride
Show/Hide
|
C17H19ClFNO
|
1
|
| 1 |
EC50 = 2190 nM
|
|
|
|
CP0856415
|
N-(3-Methoxyphenyl)-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine hydrochloride
Show/Hide
|
C20H29ClN6O
|
1
|
| 1 |
EC50 = 2300 nM
|
|
|
|
CP0889420
|
(-)-((1R,2R)-2-(5-chloro-2-isopropoxyphenyl)cyclopropyl)methanamine trifluoroacetate
Show/Hide
|
C15H19ClF3NO3
|
1
|
| 1 |
EC50 = 2481 nM
|
|
|
|
CP0426727
|
N-[4-[[(1S,2S)-2-(2,3-dichlorophenyl)cyclopropyl]methyl-propylamino]butyl]-1H-indole-2-carboxamide;hydrochloride
Show/Hide
|
C26H32Cl3N3O
|
1
|
| 1 |
EC50 = 2549 nM
|
|
|
|
CP0640830
|
tranylcypromine
Show/Hide
|
C18H22N2
|
1
|
| 1 |
EC50 = 2697 nM
|
|
|
|
CP0548537
|
(5-methyl-2-naphthalen-1-yl-1,3-thiazol-4-yl)-morpholin-4-ylmethanone
Show/Hide
|
C19H18N2O2S
|
1
|
| 1 |
EC50 = 2780 nM
|
|
|
|
CP0845431
|
trans-(2-Naphthalen-2-ylcyclopropyl)methylamine Hydrochloride
Show/Hide
|
C14H16ClN
|
1
|
| 1 |
EC50 = 2902 nM
|
|
|
|
CP0896641
|
(+/-)-Cis-(2-Phenylcyclopropyl)methylamine Hydrochloride
Show/Hide
|
C10H14ClN
|
1
|
| 1 |
EC50 = 3019 nM
|
|
|
|
CP0456445
|
[2-(2,3-dichlorophenyl)-1,3-thiazol-4-yl]-piperidin-1-ylmethanone
Show/Hide
|
C15H14Cl2N2OS
|
1
|
| 1 |
EC50 = 3100 nM
|
|
|
|
CP0378393
|
2,3,4,5-tetrahydro-1H-3-benzazepine
Show/Hide
|
C10H13N
|
1
|
| 1 |
EC50 = 3162.28 nM
|
|
|
|
CP0867771
|
rac-trans-C-[2-(2'-Fluoro-4-methoxy-biphenyl-3-yl)-cyclopropyl]-methylamine Hydrochloride
Show/Hide
|
C17H19ClFNO
|
1
|
| 1 |
EC50 = 3310 nM
|
|
|
|
CP0388670
|
N-[[(1S,2S)-2-phenylcyclopropyl]methyl]propan-2-amine
Show/Hide
|
C13H19N
|
1
|
| 1 |
EC50 = 3416 nM
|
|
|
|
CP0895921
|
rac-trans-C-[2-(4-Methoxy-2'-methyl-biphenyl-3-yl)-cyclopropyl]-methylamine Hydrochloride
Show/Hide
|
C18H22ClNO
|
1
|
| 1 |
EC50 = 3470 nM
|
|
|
|
CP0143982
|
N-[4-[[(1S,2S)-2-(2,3-dichlorophenyl)cyclopropyl]methyl-propylamino]butyl]naphthalene-2-carboxamide;hydrochloride
Show/Hide
|
C28H33Cl3N2O
|
1
|
| 1 |
EC50 = 3538 nM
|
|
|
|
CP0867187
|
rac-trans-C-[2-(4-Methoxy-biphenyl-3-yl)-cyclopropyl]-methylamine Hydrochloride
Show/Hide
|
C17H20ClNO
|
1
|
| 1 |
EC50 = 3800 nM
|
|
|
|
CP0468761
|
1-ethyl-5-(3-methylimidazol-4-yl)-3-naphthalen-1-ylpyrazole
Show/Hide
|
C19H18N4
|
1
|
| 1 |
EC50 = 3850 nM
|
|
|
|
CP0521788
|
5-(1-ethyl-5-pyridazin-3-ylpyrazol-3-yl)quinoline
Show/Hide
|
C18H15N5
|
1
|
| 1 |
EC50 = 4528 nM
|
|
|
|
CP0521792
|
[2-(2-chlorophenyl)-1,3-thiazol-4-yl]-morpholin-4-ylmethanone
Show/Hide
|
C14H13ClN2O2S
|
1
|
| 1 |
EC50 = 4600 nM
|
|
|
|
CP0374097
|
N-benzyl-1-[(1S,2S)-2-phenylcyclopropyl]methanamine
Show/Hide
|
C17H19N
|
1
|
| 1 |
EC50 = 5697 nM
|
|
|
|
CP0859045
|
rac-trans-C-[2-(3'-Fluoro-4-methoxy-biphenyl-3-yl)-cyclopropyl]-methylamine Hydrochloride
Show/Hide
|
C17H19ClFNO
|
1
|
| 1 |
EC50 = 7240 nM
|
|
|
|
CP0894254
|
rac-trans-C-[2-(4-Methoxy-3'-methyl-biphenyl-3-yl)-cyclopropyl]-methylamine Hydrochloride
Show/Hide
|
C18H22ClNO
|
1
|
| 1 |
EC50 = 8710 nM
|
|
|
|
CP0946362
|
4-(2-(4-Methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-yl)morpholine hydrochloride
Show/Hide
|
C17H29ClN6O
|
1
|
| 1 |
EC50 = 9600 nM
|
|
|
|
CP0850270
|
trans-{2-[4-(6-Hydroxyhex-1-ynyl)phenyl]cyclopropyl}methylamine Hydrochloride
Show/Hide
|
C16H22ClNO
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0857940
|
2-(4-Methylpiperazin-1-yl)-N-ethyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine hydrochloride
Show/Hide
|
C15H27ClN6
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0857949
|
4-(2-(4-Methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-yl)thiomorpholine hydrochloride
Show/Hide
|
C17H29ClN6S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0887187
|
(S,Z)-5-phenylpent-4-en-2-amine
Show/Hide
|
C11H15N
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0920610
|
(Z)-5-phenylpent-4-en-2-amine
Show/Hide
|
C11H15N
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0376980
|
10-chloro-5,5-dimethyl-1,2,3,4,4a,6-hexahydropyrazino[1,2-a]quinoline
Show/Hide
|
C14H19ClN2
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Ki = 794.33 nM
|
|
|
|
CP0542443
|
(10S)-1,13-diazatricyclo[8.6.0.02,7]hexadeca-2,4,6-triene
Show/Hide
|
C14H20N2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0387273
|
N-(2-hydroxyethyl)-4-methyl-2-naphthalen-1-yl-N-propan-2-yl-1,3-thiazole-5-carboxamide
Show/Hide
|
C20H22N2O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0456446
|
[2-(2,3-dichlorophenyl)-4-methyl-1,3-thiazol-5-yl]-morpholin-4-ylmethanone
Show/Hide
|
C15H14Cl2N2O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0476135
|
morpholin-4-yl-(2-pyridin-3-yl-1,3-thiazol-4-yl)methanone
Show/Hide
|
C13H13N3O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0517757
|
[2-(2-chloro-3-fluorophenyl)-1,3-thiazol-4-yl]-morpholin-4-ylmethanone
Show/Hide
|
C14H12ClFN2O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0521791
|
N-(2-methoxyethyl)-4-methyl-2-naphthalen-1-yl-1,3-thiazole-5-carboxamide
Show/Hide
|
C18H18N2O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0543223
|
[2-(2,3-dichlorophenyl)-1,3-thiazol-5-yl]-morpholin-4-ylmethanone
Show/Hide
|
C14H12Cl2N2O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0548045
|
[2-(2,4-dichlorophenyl)-1,3-thiazol-4-yl]-morpholin-4-ylmethanone
Show/Hide
|
C14H12Cl2N2O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0559070
|
4-methyl-2-naphthalen-1-yl-1,3-thiazole-5-carboxamide
Show/Hide
|
C15H12N2OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0570861
|
(4aR)-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a][1,6]naphthyridine
Show/Hide
|
C11H15N3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0057817
|
2-[[2-(4-bromo-2,5-dimethoxyphenyl)ethylamino]methyl]-6-methoxyphenol
Show/Hide
|
C18H22BrNO4
|
1
|
| 1 |
EC50 = 15488.17 nM
|
|
|
|
CP0228054
|
(3aS,6aS)-5-(4-(2,5-dichlorophenyl)pyrimidin-2-yl)-octahydropyrrolo[3,4-b]pyrrole
Show/Hide
|
C16H16Cl2N4
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0461917
|
(3aS,6aS)-5-(4-(2,5-difluorophenyl)pyrimidin-2-yl)-octahydropyrrolo[3,4-b]pyrrole
Show/Hide
|
C16H16F2N4
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0500594
|
(3aS,6aS)-5-(4-(trifluoromethyl)pyrimidin-2-yl)-octahydropyrrolo[3,4-b]pyrrole
Show/Hide
|
C11H13F3N4
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0199405
|
2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2,6-dimethoxyphenyl)methyl]ethanamine
Show/Hide
|
C19H24BrNO4
|
1
|
| 1 |
EC50 = 87096.36 nM
|
|
|
|
CP0486544
|
(3aS,6aS)-1-(4-(2,5-difluorophenyl)pyrimidin-2-yl)-octahydropyrrolo[3,4-b]pyrrole
Show/Hide
|
C16H16F2N4
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0525915
|
(3aS,6aS)-1-(4-(2,5-dichlorophenyl)pyrimidin-2-yl)-octahydropyrrolo[3,4-b]pyrrole
Show/Hide
|
C16H16Cl2N4
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0845372
|
trans-[2-(4'-Trifluoromethybiphenyl-3-yl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C17H17ClF3N
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0845426
|
trans-C-[2-(3-Benzofuran-2-ylphenyl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C18H18ClNO
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0845432
|
trans-N-[2-(2-Aminomethylcyclopropyl)phenyl]acetamide Hydrochloride
Show/Hide
|
C12H17ClN2O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0850284
|
trans-[2-(4'-Fluorobiphenyl-4-yl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C16H17ClFN
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0850285
|
trans-N-[3-(2-Aminomethylcyclopropyl)phenyl]acetamide Hydrochloride
Show/Hide
|
C12H17ClN2O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0852024
|
trans-N-[3-(2-Aminomethylcyclopropyl)phenyl]benzamide Hydrochloride
Show/Hide
|
C17H19ClN2O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0852025
|
trans-1-[2-(2-Aminomethylcyclopropyl)phenyl]-3-(4-chlorophenyl)urea Hydrochloride
Show/Hide
|
C17H19Cl2N3O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0852026
|
trans-N-[2-(2-Aminomethylcyclopropyl)phenyl]benzamide Hydrochloride
Show/Hide
|
C17H19ClN2O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0880099
|
trans-[2-(4'-Cyanobiphenyl-3-yl)cyclopropyl]methylamine Hydrochloride
Show/Hide
|
C17H17ClN2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0408281
|
5,5-dimethyl-1,2,3,4,4a,6-hexahydropyrazino[1,2-a]quinoline
Show/Hide
|
C14H20N2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0530848
|
(5aR)-9-benzyl-10-methoxy-1,2,3,4,5,5a,6,7-octahydro-[1,4]diazepino[1,2-a]quinoline
Show/Hide
|
C21H26N2O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0569743
|
(4aR)-7-(cyclobutylmethyl)-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a][1,6]naphthyridine
Show/Hide
|
C16H23N3
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0456443
|
1-ethyl-5-(2-methylpyrazol-3-yl)-3-naphthalen-1-ylpyrazole
Show/Hide
|
C19H18N4
|
1
|
| 1 |
EC50 >= 3460 nM
|
|
|
|
CP0413002
|
[4-(hydroxymethyl)piperidin-1-yl]-(2-naphthalen-1-yltetrazol-5-yl)methanone
Show/Hide
|
C18H19N5O2
|
1
|
| 1 |
EC50 >= 4100 nM
|
|
|
|
CP0913264
|
trans-{2-[3-(3-Hydroxy-3-methylbut-1-ynyl)phenyl]cyclopropyl}-methylamine Hydrochloride
Show/Hide
|
C15H20ClNO
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0055944
|
N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide
Show/Hide
|
C27H31F3N4O7S
|
2
|
| 1 |
IC50 = 1.5 nM
|
|
|
| 2 |
Ki = 0.6 nM
|
|
|
|
CP0348221
|
N-[4-[[(1S,2S)-2-(5-fluoro-2-methoxyphenyl)cyclopropyl]methyl-propylamino]butyl]-4-pyridin-2-ylbenzamide;hydrochloride
Show/Hide
|
C30H37ClFN3O2
|
1
|
| 1 |
IC50 = 860 nM
|
|
|
|
CP0348222
|
N-[4-[[(1R,2R)-2-(2,3-dichlorophenyl)cyclopropyl]methyl-propylamino]butyl]-4-pyridin-2-ylbenzamide;hydrochloride
Show/Hide
|
C29H34Cl3N3O
|
1
|
| 1 |
IC50 = 10100 nM
|
|
|
|
CP0533678
|
N-[4-[[(1R,2R)-2-(5-fluoro-2-methoxyphenyl)cyclopropyl]methyl-propylamino]butyl]-4-pyridin-2-ylbenzamide;hydrochloride
Show/Hide
|
C30H37ClFN3O2
|
1
|
| 1 |
IC50 = 14500 nM
|
|
|
|
CP0267566
|
N-[4-[[(1R,2R)-2-(2,3-dichlorophenyl)cyclopropyl]methyl-propylamino]butyl]naphthalene-2-carboxamide;hydrochloride
Show/Hide
|
C28H33Cl3N2O
|
1
|
| 1 |
IC50 = 16100 nM
|
|
|
|
CP0382966
|
N-[4-[[(1R,2R)-2-(2,3-dichlorophenyl)cyclopropyl]methyl-propylamino]butyl]-1H-indole-2-carboxamide;hydrochloride
Show/Hide
|
C26H32Cl3N3O
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0845073
|
[N-methyl-3H]LSD
Show/Hide
|
C20H25N3O
|
1
|
| 1 |
Kd = 52.84 nM
|
|
|
|
CP0270952
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid [4-methyl-3-(4-methyl-pyridin-3-yl)-phenyl]-amide
Show/Hide
|
C24H22F3N3O2
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0363120
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (4'-methyl-[3,3']bipyridinyl-5-yl)-amide
Show/Hide
|
C22H19F3N4O2
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0403961
|
N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-5-methylsulfanyl-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C22H19F3N4O2S
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0470896
|
5-methyl-N-[5-methyl-6-(pyridin-2-ylmethoxy)pyridin-3-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C23H21F3N4O2
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0439644
|
5-fluoro-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-7-(trifluoromethyl)-3H-isoindol-1-one
Show/Hide
|
C24H26F4N2O3
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0267885
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (4-methoxy-3-pyridin-3-yl-phenyl)-amide
Show/Hide
|
C23H20F3N3O3
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0292349
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (7-pyridin-3-yl-2,3-dihydro-benzofuran-5-yl)-amide
Show/Hide
|
C24H20F3N3O3
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0448658
|
6-chloro-N-[6-(4-chloropyridin-3-yl)oxypyridin-3-yl]-5-methyl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C20H16Cl2N4O2
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0445641
|
5-methyl-N-[6-(pyridin-2-ylmethoxy)pyridin-3-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C22H19F3N4O2
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0448376
|
5-methyl-N-[6-(pyrazin-2-ylmethoxy)pyridin-3-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H18F3N5O2
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0112788
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (3-ethyl-5-pyridin-3-yl-phenyl)-amide
Show/Hide
|
C24H22F3N3O2
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0122688
|
N-(3-fluoro-4-methyl-5-pyridin-3-ylphenyl)-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C23H19F4N3O2
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0151120
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid [3-(4-methyl-pyridin-3-yl)-phenyl]-amide
Show/Hide
|
C23H20F3N3O2
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0170950
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid [6-(2-methyl-pyridin-3-yloxy)-pyridin-3-yl]-amide
Show/Hide
|
C22H19F3N4O3
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0363121
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid [4-chloro-3-(4-methyl-pyridin-3-yl)-phenyl]-amide
Show/Hide
|
C23H19ClF3N3O2
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0363973
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid [3,4']bipyridinyl-5-ylamide
Show/Hide
|
C21H17F3N4O2
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0393469
|
6-chloro-N-[5-chloro-6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-5-methyl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H18Cl2N4O2
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0293951
|
(E)-3-(2-chlorophenyl)-1-[5-methoxy-6-(2-piperidin-1-ylethoxy)-2,3-dihydroindol-1-yl]prop-2-en-1-one
Show/Hide
|
C25H29ClN2O3
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0244165
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid [3,3']bipyridinyl-5-ylamide
Show/Hide
|
C21H17F3N4O2
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0467596
|
6-bromo-5-methyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H19BrN4O2
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0378897
|
1-(3,4-dichlorophenyl)-3-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]imidazolidin-2-one
Show/Hide
|
C23H27Cl2N3O3
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0461882
|
7-bromo-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-3H-isoindol-1-one
Show/Hide
|
C23H27BrN2O3
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0049120
|
CAS_181632-25-7
Show/Hide
|
C21H19ClN4O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0096796
|
5-Methyl-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid [6-(2-methyl-pyridin-3-yloxy)-pyridin-3-yl]-amide
Show/Hide
|
C22H19F3N4O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0099734
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (3-fluoro-5-pyridin-3-yl-phenyl)-amide
Show/Hide
|
C22H17F4N3O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0131104
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (3-pyridin-3-yl-phenyl)-amide
Show/Hide
|
C22H18F3N3O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0140321
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (4-methyl-3-pyridin-3-yl-phenyl)-amide
Show/Hide
|
C23H20F3N3O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0431639
|
4,6-dichloro-5-methyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H18Cl2N4O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0465006
|
6-chloro-5-methyl-N-[6-(4-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H19ClN4O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0486643
|
1-(3,5-difluorophenyl)-3-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]imidazolidin-2-one
Show/Hide
|
C23H27F2N3O3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0421901
|
6,7-dichloro-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-3H-isoindol-1-one
Show/Hide
|
C23H26Cl2N2O3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0056798
|
(S)-1-(5,6-difluoro-1H-indol-1-yl)propan-2-amine
Show/Hide
|
C11H12F2N2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0112832
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid [6-(pyridin-3-yloxy)-pyridin-3-yl]-amide
Show/Hide
|
C21H17F3N4O3
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0392821
|
5-bromo-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H16BrF3N4O2
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0392976
|
5-chloro-6-methyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H19ClN4O2
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0449808
|
6-chloro-N-[6-(2-chloropyridin-3-yl)oxypyridin-3-yl]-5-methyl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C20H16Cl2N4O2
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0480551
|
N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-4-(trifluoromethyl)-1,2,7,8-tetrahydrofuro[3,2-e]indole-6-carboxamide
Show/Hide
|
C23H19F3N4O3
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0451267
|
6-chloro-5-methyl-N-[6-(pyridin-4-ylmethoxy)pyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H19ClN4O2
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0428053
|
1-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]-3-phenylimidazolidin-2-one
Show/Hide
|
C23H29N3O3
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0486642
|
1-(3,4-dichlorophenyl)-3-[3-[2-(dimethylamino)ethoxy]-4-methoxyphenyl]imidazolidin-2-one
Show/Hide
|
C20H23Cl2N3O3
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0399954
|
7-chloro-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-3-methyl-3H-isoindol-1-one
Show/Hide
|
C24H29ClN2O3
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0433359
|
5,7-dichloro-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-6-methyl-3H-isoindol-1-one
Show/Hide
|
C24H28Cl2N2O3
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0199724
|
5-methylsulfanyl-N-(3-pyridin-3-ylphenyl)-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C22H18F3N3OS
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0375930
|
6-chloro-5-methyl-N-[6-(2-propylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C23H23ClN4O2
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0380634
|
N-[5-chloro-6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-5-methyl-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C22H18ClF3N4O2
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0437813
|
6-fluoro-5-methyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H19FN4O2
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0449912
|
4-bromo-5-methyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H19BrN4O2
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0503991
|
6-chloro-5-methyl-N-[5-methyl-6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C22H21ClN4O2
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0486640
|
1-(3-fluorophenyl)-3-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]imidazolidin-2-one
Show/Hide
|
C23H28FN3O3
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0399956
|
7-chloro-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-3H-isoindol-1-one
Show/Hide
|
C23H27ClN2O3
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0439645
|
2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-7-(trifluoromethyl)-3H-isoindol-1-one
Show/Hide
|
C24H27F3N2O3
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0442439
|
5,7-dichloro-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-3H-isoindol-1-one
Show/Hide
|
C23H26Cl2N2O3
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0403111
|
2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-3H-[1]benzothiolo[2,3-c]pyrrol-1-one
Show/Hide
|
C25H28N2O3S
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0204187
|
1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-3-(4-chlorophenyl)urea
Show/Hide
|
C23H25BrClN5O2
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0380656
|
6-bromo-5-methylsulfanyl-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C15H14BrN3OS
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0465010
|
6-iodo-5-methylsulfanyl-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C15H14IN3OS
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0053024
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (3-bromo-5-pyridin-3-yl-phenyl)-amide
Show/Hide
|
C22H17BrF3N3O2
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0406015
|
5-methyl-N-[5-(2-methylpyridin-3-yl)oxypyrazin-2-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H18F3N5O2
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0406525
|
6-chloro-5-methyl-N-[6-(2-methylpyridin-3-yl)oxypyridazin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C20H18ClN5O2
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0438717
|
5,6-Dichloro-2,3-dihydro-indole-1-carboxylic acid [6-(2-methyl-pyridin-3-yloxy)-pyridin-3-yl]-amide
Show/Hide
|
C20H16Cl2N4O2
|
2
|
| 1 |
Ki = 1.995 nM
|
|
|
| 2 |
Ki = 2 nM
|
|
|
|
CP0462793
|
5-methyl-N-[6-(4-methylpyrimidin-5-yl)oxypyridin-3-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H18F3N5O2
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0487374
|
6-chloro-N-[6-(2-ethylpyridin-3-yl)oxypyridin-3-yl]-5-methyl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C22H21ClN4O2
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0378895
|
1-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]-3-[4-methyl-3-(trifluoromethyl)phenyl]imidazolidin-2-one
Show/Hide
|
C25H30F3N3O3
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0421896
|
5,7-dichloro-2-[3-[2-(4,4-dimethylpiperidin-1-yl)ethoxy]-4-methoxyphenyl]-3H-isoindol-1-one
Show/Hide
|
C24H28Cl2N2O3
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0433356
|
7-chloro-4,5-difluoro-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-3H-isoindol-1-one
Show/Hide
|
C23H25ClF2N2O3
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0889436
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-ethoxyphenyl]-3-(4-chlorophenyl)urea
Show/Hide
|
C19H18BrClN4O2
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0082470
|
(6aR,9R)-4,7-dimethyl-N-[(1S)-1-methylolpropyl]-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-9-carboxamide;maleate
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0046569
|
5-Methylsulfanyl-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid pyridin-3-ylamide
Show/Hide
|
C16H14F3N3OS
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0408417
|
4,6-dichloro-5-methylsulfanyl-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C15H13Cl2N3OS
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0353541
|
N-[3-(2,4-dimethylpyridin-3-yl)phenyl]-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C24H22F3N3O2
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0379048
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (5-pyridin-3-yl-biphenyl-3-yl)-amide
Show/Hide
|
C28H22F3N3O2
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0375058
|
5-ethyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C23H21F3N4O2
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0403983
|
6-chloro-5-methyl-N-[6-(pyridin-2-ylmethoxy)pyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H19ClN4O2
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0448692
|
5-methyl-N-[4-(pyridin-2-ylmethoxy)phenyl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C23H20F3N3O2
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0399951
|
5,6-dichloro-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-7-methyl-3H-isoindol-1-one
Show/Hide
|
C24H28Cl2N2O3
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0427781
|
2-[3-[2-(azepan-1-yl)ethoxy]-4-methoxyphenyl]-5,7-dichloro-3H-isoindol-1-one
Show/Hide
|
C23H26Cl2N2O3
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0433357
|
2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-7-methyl-3H-isoindol-1-one
Show/Hide
|
C24H30N2O3
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0433360
|
5,7-dichloro-2-[4-methoxy-3-[2-(3-methylpiperidin-1-yl)ethoxy]phenyl]-3H-isoindol-1-one
Show/Hide
|
C23H26Cl2N2O3
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0394711
|
7-chloro-2-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]-4-methyl-3H-pyrrolo[3,4-b]indol-1-one
Show/Hide
|
C25H28ClN3O3
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0400066
|
5-fluoro-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-4-methyl-3H-pyrrolo[3,4-b]indol-1-one
Show/Hide
|
C26H30FN3O3
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0434031
|
7-fluoro-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-4-methyl-3H-pyrrolo[3,4-b]indol-1-one
Show/Hide
|
C26H30FN3O3
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0887366
|
1-[3-(4-Bromo-2-isopropyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(4-chlorophenyl)urea
Show/Hide
|
C20H20BrClN4O2
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0018076
|
5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-carboxylic acid pyridin-3-ylamide
Show/Hide
|
C17H16N4O
|
3
|
| 1 |
Ki = 2.8 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
| 3 |
Ki = 12.59 nM
|
|
|
|
CP0457526
|
1-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
Show/Hide
|
C25H28F3N5O2
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0500048
|
1-(3-(4-chloro-1-methyl-1H-pyrazol-5-yl)-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-3-(4-chlorophenyl)urea
Show/Hide
|
C23H25Cl2N5O2
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0376845
|
6-Iodo-5-methyl-2,3-dihydro-indole-1-carboxylic acid pyridin-3-ylamide
Show/Hide
|
C15H14IN3O
|
2
|
| 1 |
Ki = 3.162 nM
|
|
|
| 2 |
Ki = 3.2 nM
|
|
|
|
CP0400775
|
6-Chloro-5-iodo-2,3-dihydro-indole-1-carboxylic acid pyridin-3-ylamide
Show/Hide
|
C14H11ClIN3O
|
2
|
| 1 |
Ki = 3.162 nM
|
|
|
| 2 |
Ki = 3.2 nM
|
|
|
|
CP0419051
|
5-propan-2-yloxy-N-pyridin-3-yl-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C18H18F3N3O2
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0449625
|
5-ethylsulfanyl-N-pyridin-3-yl-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C17H16F3N3OS
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0151079
|
N-(4-tert-butyl-3-pyridin-3-ylphenyl)-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C26H26F3N3O2
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0217161
|
5-methylsulfanyl-N-(3-pyridin-4-ylphenyl)-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C22H18F3N3OS
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0373258
|
5-Iodo-2,3-dihydro-indole-1-carboxylic acid [6-(2-methyl-pyridin-3-yloxy)-pyridin-3-yl]-amide
Show/Hide
|
C20H17IN4O2
|
2
|
| 1 |
Ki = 3.162 nM
|
|
|
| 2 |
Ki = 3.2 nM
|
|
|
|
CP0376713
|
6-chloro-5-methyl-N-[2-(2-methylpyridin-3-yl)oxypyrimidin-5-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C20H18ClN5O2
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0380585
|
5-Bromo-2,3-dihydro-indole-1-carboxylic acid [6-(2-methyl-pyridin-3-yloxy)-pyridin-3-yl]-amide
Show/Hide
|
C20H17BrN4O2
|
2
|
| 1 |
Ki = 3.162 nM
|
|
|
| 2 |
Ki = 3.2 nM
|
|
|
|
CP0410888
|
4,5-dichloro-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C20H16Cl2N4O2
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0442600
|
5-methyl-N-[6-(2-methylpyridin-3-yl)oxypyridazin-3-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H18F3N5O2
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0397623
|
5-methyl-N-[6-(2-pyridin-2-ylethyl)pyridin-3-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C23H21F3N4O
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0476069
|
1-(3,4-dichlorophenyl)-3-[4-methoxy-3-(2-morpholin-4-ylethoxy)phenyl]imidazolidin-2-one
Show/Hide
|
C22H25Cl2N3O4
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0399950
|
2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-5,7-dimethyl-3H-isoindol-1-one
Show/Hide
|
C25H32N2O3
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0421898
|
7-chloro-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-4-methyl-3H-pyrrolo[3,4-b]indol-1-one
Show/Hide
|
C26H30ClN3O3
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0437826
|
2-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]-3H-[1]benzothiolo[2,3-c]pyrrol-1-one
Show/Hide
|
C24H26N2O3S
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0880334
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(4-chloro-3-trifluoromethylphenyl)urea
Show/Hide
|
C19H15BrClF3N4O2
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0399906
|
N-[5-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]-2-methylphenyl]-4-phenylbenzamide
Show/Hide
|
C29H28ClN5O2
|
1
|
| 1 |
Ki = 3.89 nM
|
|
|
|
CP0410835
|
5-methylsulfanyl-6-(1,1,2,2,2-pentafluoroethyl)-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C17H14F5N3OS
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0467589
|
6-Bromo-5-methyl-2,3-dihydro-indole-1-carboxylic acid pyridin-3-ylamide
Show/Hide
|
C15H14BrN3O
|
2
|
| 1 |
Ki = 3.981 nM
|
|
|
| 2 |
Ki = 4 nM
|
|
|
|
CP0497635
|
4,6-dichloro-5-methyl-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C15H13Cl2N3O
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0381058
|
N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-5-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H17F3N4O2
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0392948
|
6-Chloro-2,3-dihydro-indole-1-carboxylic acid [6-(2-methyl-pyridin-3-yloxy)-pyridin-3-yl]-amide
Show/Hide
|
C20H17ClN4O2
|
2
|
| 1 |
Ki = 3.981 nM
|
|
|
| 2 |
Ki = 4 nM
|
|
|
|
CP0409875
|
5-methyl-N-[6-[(3-methylimidazol-4-yl)methoxy]pyridin-3-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H20F3N5O2
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0429347
|
5-methyl-N-[6-[(3-methylpyridin-2-yl)methoxy]pyridin-3-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C23H21F3N4O2
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0436150
|
1-[3-[2-(dimethylamino)ethoxy]-4-methoxyphenyl]-3-(3-fluorophenyl)imidazolidin-2-one
Show/Hide
|
C20H24FN3O3
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0421894
|
7-chloro-2-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]-3H-isoindol-1-one
Show/Hide
|
C22H25ClN2O3
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0437827
|
6-chloro-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-4-methyl-3H-pyrrolo[3,4-b]indol-1-one
Show/Hide
|
C26H30ClN3O3
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0846108
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(4-bromophenyl)urea
Show/Hide
|
C18H16Br2N4O2
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0846956
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(4-trifluoromethylphenyl)urea
Show/Hide
|
C19H16BrF3N4O2
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0852975
|
1-[3-(4-Bromo-2-isopropyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(4-fluorophenyl)urea
Show/Hide
|
C20H20BrFN4O2
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0113507
|
(R,S)-1-(5-bromo-1H-indol-1-yl)propan-2-amine
Show/Hide
|
C11H13BrN2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0290665
|
1-(6-fluoroindol-1-yl)propan-2-amine
Show/Hide
|
C11H13FN2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0398351
|
(2S,4R)-4-(3-bromophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21BrClN
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0398760
|
(2S,4R)-N,N-dimethyl-4-(3-phenylphenyl)-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C24H26ClN
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0480606
|
6-chloro-5-ethyl-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C16H16ClN3O
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0171734
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (4-chloro-3-pyridin-3-yl-phenyl)-amide
Show/Hide
|
C22H17ClF3N3O2
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0199722
|
5-methoxy-N-(4-pyridin-4-ylphenyl)-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C22H18F3N3O2
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0353555
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid [3-(2-methyl-pyridin-3-yl)-phenyl]-amide
Show/Hide
|
C23H20F3N3O2
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0353662
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (5-phenyl-pyridin-3-yl)-amide
Show/Hide
|
C22H18F3N3O2
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0402316
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid [2,3']bipyridinyl-5-ylamide
Show/Hide
|
C21H17F3N4O2
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0375965
|
N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H17F3N4O2
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0423027
|
6-chloro-5-methyl-N-[6-[(1-methylimidazol-2-yl)methoxy]pyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C20H20ClN5O2
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0448619
|
5-methyl-N-[6-(pyridin-2-ylmethoxy)pyridazin-3-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H18F3N5O2
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0448637
|
6-chloro-5-methyl-N-[6-(1,3-thiazol-2-ylmethoxy)pyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C19H17ClN4O2S
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0448999
|
5-methyl-N-[6-(pyridin-2-yloxymethyl)pyridin-3-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C22H19F3N4O2
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0045725
|
(4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene-4-carboxamide
Show/Hide
|
C20H25N3O
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0421903
|
5,6-dichloro-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-3H-isoindol-1-one
Show/Hide
|
C23H26Cl2N2O3
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0394680
|
6-chloro-2-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]-4-methyl-3H-pyrrolo[3,4-b]indol-1-one
Show/Hide
|
C25H28ClN3O3
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0403098
|
3-hydroxy-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-4-methyl-3H-pyrrolo[3,4-b]indol-1-one
Show/Hide
|
C26H31N3O4
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0514600
|
1-(4-(2-(azetidin-1-yl)ethoxy)-3-(1-methyl-1H-pyrazol-5-yl)phenyl)-3-(4-chlorophenyl)urea
Show/Hide
|
C22H24ClN5O2
|
1
|
| 1 |
Ki = 5.4 nM
|
|
|
|
CP0245277
|
(R,S)-1-(5-fluoro-1H-indol-1-yl)propan-2-amine
Show/Hide
|
C11H13FN2
|
1
|
| 1 |
Ki = 6.3 nM
|
|
|
|
CP0377948
|
6-Chloro-5-methyl-2,3-dihydro-indole-1-carboxylic acid pyridin-3-ylamide
Show/Hide
|
C15H14ClN3O
|
2
|
| 1 |
Ki = 6.3 nM
|
|
|
| 2 |
Ki = 6.31 nM
|
|
|
|
CP0380991
|
5-Chloro-2,3-dihydro-indole-1-carboxylic acid [6-(2-methyl-pyridin-3-yloxy)-pyridin-3-yl]-amide
Show/Hide
|
C20H17ClN4O2
|
2
|
| 1 |
Ki = 6.3 nM
|
|
|
| 2 |
Ki = 6.31 nM
|
|
|
|
CP0400792
|
6-Chloro-5-fluoro-2,3-dihydro-indole-1-carboxylic acid [6-(2-methyl-pyridin-3-yloxy)-pyridin-3-yl]-amide
Show/Hide
|
C20H16ClFN4O2
|
2
|
| 1 |
Ki = 6.3 nM
|
|
|
| 2 |
Ki = 6.31 nM
|
|
|
|
CP0465985
|
6-chloro-5-methylsulfanyl-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C15H14ClN3OS
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0380979
|
5-propylsulfanyl-N-pyridin-3-yl-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C18H18F3N3OS
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0430077
|
5-ethoxy-N-pyridin-3-yl-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C17H16F3N3O2
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0510128
|
5-chloro-N-pyridin-3-yl-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C15H11ClF3N3O
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0299498
|
N-[5-(4-fluorophenyl)pyridin-3-yl]-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C22H17F4N3O2
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0397594
|
5-methyl-N-[6-[(6-methylpyridin-2-yl)methoxy]pyridin-3-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C23H21F3N4O2
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0457268
|
N-[6-(pyridin-2-ylmethoxy)pyridin-3-yl]-5-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H17F3N4O2
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0476070
|
1-(3-fluorophenyl)-3-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]imidazol-2-one
Show/Hide
|
C23H26FN3O3
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0399952
|
5,7-dichloro-2-[3-[2-[(2R,6S)-2,6-dimethylpiperidin-1-yl]ethoxy]-4-methoxyphenyl]-3H-isoindol-1-one
Show/Hide
|
C24H28Cl2N2O3
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0399953
|
4-fluoro-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-7-(trifluoromethyl)-3H-isoindol-1-one
Show/Hide
|
C24H26F4N2O3
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0462887
|
6,7-dichloro-2-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]-4-methyl-3H-pyrrolo[3,4-b]indol-1-one
Show/Hide
|
C25H27Cl2N3O3
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0859962
|
2-(4-methoxy-3-(2-(piperidin-1-yl)ethoxy)phenyl)-4-methyl-2,3-dihydropyrrolo[3,4-b]indol-1(4H)-one
Show/Hide
|
C25H30ClN3O3
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0398758
|
(2S,4R)-4-cyclohexyl-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H28ClN
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0245643
|
(R,S)-1-(5-chloro-1H-indol-1-yl)propan-2-amine
Show/Hide
|
C11H13ClN2
|
1
|
| 1 |
Ki = 7.9 nM
|
|
|
|
CP0377030
|
5,6-Dichloro-2,3-dihydro-indole-1-carboxylic acid pyridin-3-ylamide
Show/Hide
|
C14H11Cl2N3O
|
2
|
| 1 |
Ki = 7.9 nM
|
|
|
| 2 |
Ki = 7.943 nM
|
|
|
|
CP0438718
|
4-Bromo-5-methyl-2,3-dihydro-indole-1-carboxylic acid pyridin-3-ylamide
Show/Hide
|
C15H14BrN3O
|
2
|
| 1 |
Ki = 7.9 nM
|
|
|
| 2 |
Ki = 7.943 nM
|
|
|
|
CP0432868
|
N-[6-(pyridin-2-ylmethoxy)pyridin-3-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H17F3N4O2
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0392080
|
1-[4-methoxy-3-(2-morpholin-4-ylethoxy)phenyl]-3-[4-methyl-3-(trifluoromethyl)phenyl]imidazolidin-2-one
Show/Hide
|
C24H28F3N3O4
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0464498
|
1-(3,5-difluorophenyl)-3-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]imidazol-2-one
Show/Hide
|
C23H25F2N3O3
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0483366
|
(2S,4R)-4-(3-chlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21Cl2N
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0473955
|
1-(4-chlorophenyl)-3-(4-(2-(diethylamino)ethoxy)-3-(1-methyl-1H-pyrazol-5-yl)phenyl)urea
Show/Hide
|
C23H28ClN5O2
|
1
|
| 1 |
Ki = 8.8 nM
|
|
|
|
CP0494717
|
1-(4-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)urea
Show/Hide
|
C23H26ClN5O2
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0573221
|
1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-3-(4-fluorophenyl)urea
Show/Hide
|
C23H25BrFN5O2
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0255767
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid pyridin-3-ylamide
Show/Hide
|
C16H14F3N3O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0449806
|
5-Chloro-6-methyl-2,3-dihydro-indole-1-carboxylic acid pyridin-3-ylamide
Show/Hide
|
C15H14ClN3O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0103662
|
N-(2-chloro-3-pyridin-3-ylphenyl)-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C22H17ClF3N3O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0447960
|
5-methyl-N-[6-(2-pyridin-2-ylethoxy)pyridin-3-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C23H21F3N4O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0486639
|
1-(2,3-dichlorophenyl)-3-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]imidazolidin-2-one
Show/Hide
|
C23H27Cl2N3O3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0400035
|
5,7-dichloro-2-[4-methoxy-3-[2-(2-methylpiperidin-1-yl)ethoxy]phenyl]-3H-isoindol-1-one
Show/Hide
|
C23H26Cl2N2O3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0484334
|
2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-3-oxo-1H-isoindole-4-carbonitrile
Show/Hide
|
C24H27N3O3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0064060
|
1-[3-(4-Bromo-2-methyl-2Hpyrazol-3-yl)-4-methoxyphenyl]-3-(4-chlorophenyl)urea
Show/Hide
|
C18H16BrClN4O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0661944
|
1-[3-(4-Chloro-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(4-chlorophenyl)urea
Show/Hide
|
C18H16Cl2N4O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0895178
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-isopropoxyphenyl]-3-(4-chlorophenyl)urea
Show/Hide
|
C20H20BrClN4O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0398353
|
(2S,4R)-N,N-dimethyl-4-(3-nitrophenyl)-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21ClN2O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0542186
|
(2S,4R)-N,N-dimethyl-4-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C19H21ClF3N
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0430983
|
1-(3-(4-chloro-1-methyl-1H-pyrazol-5-yl)-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-3-(2,4-difluorophenyl)urea
Show/Hide
|
C23H24ClF2N5O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0254513
|
1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-3-(2,4-difluorophenyl)urea
Show/Hide
|
C23H24BrF2N5O2
|
1
|
| 1 |
Ki = 12.4 nM
|
|
|
|
CP0402188
|
6-bromo-5-methoxy-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C15H14BrN3O2
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0505777
|
5-methoxy-6-(1,1,2,2,2-pentafluoroethyl)-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C17H14F5N3O2
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0501963
|
1-(3-fluorophenyl)-3-[4-methoxy-3-(2-morpholin-4-ylethoxy)phenyl]imidazolidin-2-one
Show/Hide
|
C22H26FN3O4
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0427779
|
5,7-dichloro-2-[4-methoxy-3-(2-morpholin-4-ylethoxy)phenyl]-3H-isoindol-1-one
Show/Hide
|
C21H22Cl2N2O4
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0436228
|
6-fluoro-2-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]-4-methyl-3H-pyrrolo[3,4-b]indol-1-one
Show/Hide
|
C25H28FN3O3
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0494768
|
1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)-3-(4-chlorophenyl)urea
Show/Hide
|
C23H25BrClN5O3
|
1
|
| 1 |
Ki = 12.7 nM
|
|
|
|
CP0430824
|
6-cyano-5-methylsulfanyl-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C16H14N4OS
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0480470
|
6-chloro-5-propan-2-yloxy-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C17H18ClN3O2
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0361307
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (4-pyridin-3-yl-phenyl)-amide
Show/Hide
|
C22H18F3N3O2
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0402304
|
4-chloro-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C20H17ClN4O2
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0431636
|
4-bromo-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C20H17BrN4O2
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0406457
|
5-bromo-N-[6-(pyridin-2-ylmethoxy)pyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C20H17BrN4O2
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0170130
|
(6aR,9R)-N-[(2R,5S,8S,8aS)-8-benzyl-8a-hydroxy-2-methyl-5-(2-methylpropyl)-3,6-dioxo-7,8-dihydro-5H-[1,3]oxazolo[3,2-a]pyrazin-2-yl]-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
Show/Hide
|
C34H39N5O5
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0433358
|
6-chloro-2-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]-3H-isoindol-1-one
Show/Hide
|
C22H25ClN2O3
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0439454
|
6-fluoro-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-4-methyl-3H-pyrrolo[3,4-b]indol-1-one
Show/Hide
|
C26H30FN3O3
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0376509
|
1-[3-(4-Bromo-2-methyl-2H- pyrazol-3-yl)-4-methoxy-phenyl]-3- (3-chloro-phenyl)-urea
Show/Hide
|
C18H16BrClN4O2
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0845374
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-trifluoromethoxyphenyl]-3-(4-chlorophenyl)urea
Show/Hide
|
C18H13BrClF3N4O2
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0850174
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(3-trifluoromethylphenyl)urea
Show/Hide
|
C19H16BrF3N4O2
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0904957
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(3,5-difluorophenyl)urea
Show/Hide
|
C18H15BrF2N4O2
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0397444
|
2-(8-fluoro-4-methyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-1-ethanamine
Show/Hide
|
C14H17FN2
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0459040
|
1-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(4-(trifluoromethyl)phenyl)urea
Show/Hide
|
C25H28F3N5O2
|
1
|
| 1 |
Ki = 18.9 nM
|
|
|
|
CP0373428
|
5-tert-butyl-6-chloro-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C18H20ClN3O
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0376565
|
6-chloro-5-propan-2-yl-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C17H18ClN3O
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0380655
|
6-chloro-5-propyl-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C17H18ClN3O
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0503988
|
5-(cyclopropylmethoxy)-N-pyridin-3-yl-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C19H18F3N3O2
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0194607
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (3-pyridin-2-yl-phenyl)-amide
Show/Hide
|
C22H18F3N3O2
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0461475
|
6-chloro-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-3H-isoindol-1-one
Show/Hide
|
C23H27ClN2O3
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0509814
|
1-(3-(4-chloro-1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)-3-(4-chlorophenyl)urea
Show/Hide
|
C23H25Cl2N5O3
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0456120
|
3-(4-methylphenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
Show/Hide
|
C14H16N2O
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0439253
|
1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(4-chlorophenyl)urea
Show/Hide
|
C24H27BrClN5O2
|
1
|
| 1 |
Ki = 21.4 nM
|
|
|
|
CP0485408
|
1-(3-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)urea
Show/Hide
|
C24H28ClN5O2
|
1
|
| 1 |
Ki = 21.7 nM
|
|
|
|
CP0441469
|
1-(3-(4-chloro-1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(4-chlorophenyl)urea
Show/Hide
|
C24H27Cl2N5O2
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0473765
|
1-(4-chlorophenyl)-3-(4-(3-(diethylamino)propoxy)-3-(1-methyl-1H-pyrazol-5-yl)phenyl)urea
Show/Hide
|
C24H30ClN5O2
|
1
|
| 1 |
Ki = 24.3 nM
|
|
|
|
CP0402199
|
4-Iodo-5-methyl-2,3-dihydro-indole-1-carboxylic acid pyridin-3-ylamide
Show/Hide
|
C15H14IN3O
|
2
|
| 1 |
Ki = 25 nM
|
|
|
| 2 |
Ki = 25.12 nM
|
|
|
|
CP0447911
|
4,5-Dichloro-2,3-dihydro-indole-1-carboxylic acid pyridin-3-ylamide
Show/Hide
|
C14H11Cl2N3O
|
2
|
| 1 |
Ki = 25 nM
|
|
|
| 2 |
Ki = 25.12 nM
|
|
|
|
CP0393569
|
5-propan-2-yl-N-pyridin-3-yl-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C18H18F3N3O
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0402187
|
6-chloro-5-ethoxy-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C16H16ClN3O2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0418941
|
5-methylsulfanyl-N-pyridin-3-yl-6-(trifluoromethoxy)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C16H14F3N3O2S
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0279990
|
N-[5-(2,6-difluorophenyl)pyridin-3-yl]-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C22H16F5N3O2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0366871
|
5-methoxy-N-(2-methyl-3-pyridin-3-ylphenyl)-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C23H20F3N3O2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0403926
|
6-chloro-5-methyl-N-[6-(pyridin-3-ylmethoxy)pyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H19ClN4O2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0442145
|
1-(3,4-dichlorophenyl)-3-[6-(2-piperidin-1-ylethoxy)pyridin-3-yl]imidazolidin-2-one
Show/Hide
|
C21H24Cl2N4O2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0421897
|
5-chloro-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-3H-isoindol-1-one
Show/Hide
|
C23H27ClN2O3
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0849887
|
1-[3-(4-Chloro-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(3,4-difluorophenyl)urea
Show/Hide
|
C18H15ClF2N4O2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0852948
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(4-isopropylphenyl)urea
Show/Hide
|
C21H23BrN4O2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0852949
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-dichlorophenyl)urea
Show/Hide
|
C18H15BrCl2N4O2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0400566
|
1-(4-chlorophenyl)-3-(4-(2-(4-methoxypiperidin-1-yl)ethoxy)-3-(1-methyl-1H-pyrazol-5-yl)phenyl)urea
Show/Hide
|
C25H30ClN5O3
|
1
|
| 1 |
Ki = 29.6 nM
|
|
|
|
CP0043142
|
trans-H2-PAT(-)
Show/Hide
|
C18H21N
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0398355
|
(2S,4R)-4-cyclooctyl-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C20H32ClN
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0398379
|
(2R,4S)-4-cyclohexyl-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H28ClN
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0388359
|
N-[3-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]phenyl]-4-phenylbenzamide
Show/Hide
|
C28H26ClN5O2
|
1
|
| 1 |
Ki = 30.2 nM
|
|
|
|
CP0380741
|
N-pyridin-3-yl-5-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C15H12F3N3O
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0418942
|
5-propan-2-ylsulfanyl-N-pyridin-3-yl-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C18H18F3N3OS
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0449802
|
methyl 6-chloro-1-(pyridin-3-ylcarbamoyl)-2,3-dihydroindole-5-carboxylate
Show/Hide
|
C16H14ClN3O3
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0409856
|
5-chloro-N-[6-(pyridin-2-ylmethoxy)pyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C20H17ClN4O2
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0476061
|
1-(2-chlorophenyl)-3-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]imidazolidin-2-one
Show/Hide
|
C23H28ClN3O3
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0444772
|
7-methoxy-2-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]-4-methyl-3H-pyrrolo[3,4-b]indol-1-one
Show/Hide
|
C26H31N3O4
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0715397
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(4-fluorophenyl)urea
Show/Hide
|
C18H16BrFN4O2
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0889437
|
1-(3,5-Bis-trifluoromethylphenyl)-3-[3-(4-bromo-2-methyl-2Hpyrazol-3-yl)-4-methoxyphenyl]urea
Show/Hide
|
C20H15BrF6N4O2
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0397518
|
1N-methyl-2-(8-fluoro-4-methyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-1-ethanamine
Show/Hide
|
C15H19FN2
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0473911
|
1-(3-(4-chloro-1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)-3-(3,5-difluorophenyl)urea
Show/Hide
|
C23H24ClF2N5O3
|
1
|
| 1 |
Ki = 37.8 nM
|
|
|
|
CP0464737
|
5-methylsulfanyl-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C15H15N3OS
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0506553
|
5-tert-butyl-4-chloro-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C18H20ClN3O
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0388246
|
5-Fluoro-2,3-dihydro-indole-1-carboxylic acid [6-(2-methyl-pyridin-3-yloxy)-pyridin-3-yl]-amide
Show/Hide
|
C20H17FN4O2
|
2
|
| 1 |
Ki = 39.81 nM
|
|
|
| 2 |
Ki = 40 nM
|
|
|
|
CP0846955
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(3-fluorophenyl)urea
Show/Hide
|
C18H16BrFN4O2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0403035
|
2-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-1-ethanamine
Show/Hide
|
C13H16N2
|
1
|
| 1 |
Ki = 41 nM
|
|
|
|
CP0398757
|
(2S,4R)-4-(3-fluorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21ClFN
|
1
|
| 1 |
Ki = 43 nM
|
|
|
|
CP0430759
|
(E)-5-[(5,6-Dichloro-1H-indol-3-yl)methylene]-2-imino-1,3-dimethylimidazolidin-4-one
Show/Hide
|
C14H12Cl2N4O
|
1
|
| 1 |
Ki = 46 nM
|
|
|
|
CP0448370
|
2-(8-chloro-2,3-dihydro[1,4]thiazino[2,3,4-hi]indol-6-yl)-1-ethanamine
Show/Hide
|
C12H13ClN2S
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0418938
|
6-Chloro-2,3-dihydro-indole-1-carboxylic acid pyridin-3-ylamide
Show/Hide
|
C14H12ClN3O
|
2
|
| 1 |
Ki = 50 nM
|
|
|
| 2 |
Ki = 50.12 nM
|
|
|
|
CP0483365
|
(2R,4R)-4-(2-chlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21Cl2N
|
1
|
| 1 |
Ki = 50 nM
|
|
|
|
CP0376584
|
5-bromo-6-methylsulfanyl-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C15H14BrN3OS
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0445215
|
5-acetyl-N-pyridin-3-yl-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C17H14F3N3O2
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0493911
|
N-pyridin-3-yl-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C15H12F3N3O
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0873297
|
3-(3-Fluoro-phenyl)-1-[4-methoxy-3-(2-piperidin-1-yl-ethoxy)-phenyl]-imidazolidine-2,4-dione
Show/Hide
|
C23H26FN3O4
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0399958
|
2-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]-3H-isoindol-1-one
Show/Hide
|
C22H26N2O3
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0442438
|
5-chloro-2-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]-3H-isoindol-1-one
Show/Hide
|
C22H25ClN2O3
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0848868
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-hydroxyphenyl]-3-(4-chlorophenyl)urea
Show/Hide
|
C17H14BrClN4O2
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0439305
|
1-(4-chlorophenyl)-3-(4-(2-(3-methoxyazetidin-1-yl)ethoxy)-3-(1-methyl-1H-pyrazol-5-yl)phenyl)urea
Show/Hide
|
C23H26ClN5O3
|
1
|
| 1 |
Ki = 50.7 nM
|
|
|
|
CP0473954
|
1-(4-(2-(diethylamino)ethoxy)-3-(1-methyl-1H-pyrazol-5-yl)phenyl)-3-(4-fluorophenyl)urea
Show/Hide
|
C23H28FN5O2
|
1
|
| 1 |
Ki = 53.2 nM
|
|
|
|
CP0398352
|
(2R,4S)-4-(4-chlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21Cl2N
|
1
|
| 1 |
Ki = 55 nM
|
|
|
|
CP0494767
|
1-(4-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)urea
Show/Hide
|
C24H28ClN5O2
|
1
|
| 1 |
Ki = 58.9 nM
|
|
|
|
CP0534489
|
1-(3-acetylphenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)urea
Show/Hide
|
C26H31N5O3
|
1
|
| 1 |
Ki = 59.1 nM
|
|
|
|
CP0235418
|
(R,S)-1-(5-methyl-1H-indol-1-yl)propan-2-amine
Show/Hide
|
C12H16N2
|
1
|
| 1 |
Ki = 63 nM
|
|
|
|
CP0503516
|
4-chloro-5-methylsulfanyl-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C15H14ClN3OS
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0845373
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(3-cyanophenyl)urea
Show/Hide
|
C19H16BrN5O2
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0846960
|
1-(3,5-Bis-trifluoromethylphenyl)-3-[3-(4-chloro-2-methyl-2Hpyrazol-3-yl)-4-methoxyphenyl]urea
Show/Hide
|
C20H15ClF6N4O2
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0103517
|
3-methyl-N-pyridin-3-yl-7,8-dihydropyrrolo[3,2-e]indole-6-carboxamide
Show/Hide
|
C17H16N4O
|
1
|
| 1 |
Ki = 66.07 nM
|
|
|
|
CP0535217
|
1-(4-chlorophenyl)-3-(4-(2-(4-hydroxypiperidin-1-yl)ethoxy)-3-(1-methyl-1H-pyrazol-5-yl)phenyl)urea
Show/Hide
|
C24H28ClN5O3
|
1
|
| 1 |
Ki = 66.2 nM
|
|
|
|
CP0513046
|
(2S,4R)-4-(4-fluorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21ClFN
|
1
|
| 1 |
Ki = 68 nM
|
|
|
|
CP0428878
|
(2R,4S)-4-(4-bromophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21BrClN
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0428881
|
(2S,4S)-4-(2-bromophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21BrClN
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0527811
|
(2R,4S)-4-(4-fluorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21ClFN
|
1
|
| 1 |
Ki = 75 nM
|
|
|
|
CP0398354
|
(2R,4R)-4-(2-bromophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21BrClN
|
1
|
| 1 |
Ki = 78 nM
|
|
|
|
CP0393105
|
5-Chloro-2,3-dihydro-indole-1-carboxylic acid pyridin-3-ylamide
Show/Hide
|
C14H12ClN3O
|
2
|
| 1 |
Ki = 79 nM
|
|
|
| 2 |
Ki = 79.43 nM
|
|
|
|
CP0403970
|
5-propan-2-yl-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C17H19N3O
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0199723
|
N-[5-(3,5-difluorophenyl)pyridin-3-yl]-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C22H16F5N3O2
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0374649
|
4-chloro-N-[6-(pyridin-2-ylmethoxy)pyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C20H17ClN4O2
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0400034
|
7-fluoro-2-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]-3H-isoindol-1-one
Show/Hide
|
C22H25FN2O3
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0336148
|
1-(4-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(2-methylpiperidin-1-yl)ethoxy)phenyl)urea
Show/Hide
|
C25H30ClN5O2
|
1
|
| 1 |
Ki = 98 nM
|
|
|
|
CP0473951
|
1-(4-(2-(1,4-oxazepan-4-yl)ethoxy)-3-(1-methyl-1H-pyrazol-5-yl)phenyl)-3-(4-chlorophenyl)urea
Show/Hide
|
C24H28ClN5O3
|
1
|
| 1 |
Ki = 98.7 nM
|
|
|
|
CP0388247
|
2,3-Dihydro-indole-1-carboxylic acid [6-(2-methyl-pyridin-3-yloxy)-pyridin-3-yl]-amide
Show/Hide
|
C20H18N4O2
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0428880
|
(2S,4R)-4-(4-bromophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21BrClN
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0485406
|
1-(4-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)urea
Show/Hide
|
C24H29ClN6O2
|
1
|
| 1 |
Ki = 102.7 nM
|
|
|
|
CP0510767
|
1-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-p-tolylurea
Show/Hide
|
C25H31N5O2
|
1
|
| 1 |
Ki = 104 nM
|
|
|
|
CP0073994
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
Show/Hide
|
C18H15BrF2N4O2
|
2
|
| 1 |
Ki = 110 nM
|
|
|
| 2 |
Ki = 158.49 nM
|
|
|
|
CP0398377
|
(2S,4R)-4-(4-chlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21Cl2N
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0398759
|
(2R,4S)-N,N-dimethyl-4-(3-nitrophenyl)-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21ClN2O2
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0375960
|
5-phenyl-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C20H17N3O
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0497777
|
6-chloro-5-phenyl-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C20H16ClN3O
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0392812
|
6-chloro-5-methyl-N-[6-(2-propan-2-ylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C23H23ClN4O2
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0400036
|
4-chloro-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-3H-isoindol-1-one
Show/Hide
|
C23H27ClN2O3
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0433361
|
2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-5,7-dimethyl-3H-isoindol-1-imine
Show/Hide
|
C25H33N3O2
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0887330
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(4-chloro-2-trifluoromethylphenyl)urea
Show/Hide
|
C19H15BrClF3N4O2
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0887364
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(4-methoxyphenyl)urea
Show/Hide
|
C19H19BrN4O3
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0534496
|
1-(4-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperazin-1-yl)ethoxy)phenyl)urea
Show/Hide
|
C23H27ClN6O2
|
1
|
| 1 |
Ki = 133 nM
|
|
|
|
CP0846054
|
1-(1-Methyl-1H-indol-5-yl)-3-pyridin-3-yl-urea
Show/Hide
|
C15H15ClN4O
|
1
|
| 1 |
Ki = 138.04 nM
|
|
|
|
CP0535397
|
1-(3,5-difluorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)urea
Show/Hide
|
C24H27F2N5O2
|
1
|
| 1 |
Ki = 147 nM
|
|
|
|
CP0485405
|
1-(4-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(3-morpholinopropoxy)phenyl)urea
Show/Hide
|
C24H28ClN5O3
|
1
|
| 1 |
Ki = 151 nM
|
|
|
|
CP0497741
|
5-methyl-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C15H15N3O
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0384378
|
1-[4-Benzyloxy-3-(4-bromo-2- methyl-2H-pyrazol-3-yl)-phenyl]-3- (4-chloro-phenyl)-urea
Show/Hide
|
C24H20BrClN4O2
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0846113
|
1-(4-Chlorophenyl)-3-[4-methoxy-3-(2-methyl-2H-pyrazol-3-yl)-phenyl]urea
Show/Hide
|
C18H17ClN4O2
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0373761
|
(E)-5-[(6-Chloro-1H-indol-3yl)methylene]-2-imino-1,3-dimethylimidazolidin-4-one
Show/Hide
|
C14H13ClN4O
|
1
|
| 1 |
Ki = 166 nM
|
|
|
|
CP0428882
|
(2R,4S)-4-(3-chlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21Cl2N
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0459039
|
1-(4-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-thiomorpholinoethoxy)phenyl)urea
Show/Hide
|
C23H26ClN5O2S
|
1
|
| 1 |
Ki = 187 nM
|
|
|
|
CP0383654
|
2-(8-fluoro-2,4-dimethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-1-ethanamine
Show/Hide
|
C15H19FN2
|
1
|
| 1 |
Ki = 194 nM
|
|
|
|
CP0429034
|
N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-4-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H17F3N4O2
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0431635
|
5-methoxy-N-[4-methyl-6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C23H21F3N4O3
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0437824
|
7-methoxy-2-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]-3H-isoindol-1-one
Show/Hide
|
C23H28N2O4
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0398376
|
(2R,4S)-4-(3-bromophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21BrClN
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0527813
|
(2R,4S)-4-(3-fluorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21ClFN
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0391906
|
3-(4-fluorophenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
Show/Hide
|
C13H14FN3
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0508273
|
1-(2-fluoro-5-methylphenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)urea
Show/Hide
|
C25H30FN5O2
|
1
|
| 1 |
Ki = 210 nM
|
|
|
|
CP0398262
|
1-(4-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)urea
Show/Hide
|
C23H26ClN5O3
|
1
|
| 1 |
Ki = 213 nM
|
|
|
|
CP0485407
|
1-(4-(2-(4-acetylpiperazin-1-yl)ethoxy)-3-(1-methyl-1H-pyrazol-5-yl)phenyl)-3-(4-chlorophenyl)urea
Show/Hide
|
C25H29ClN6O3
|
1
|
| 1 |
Ki = 216 nM
|
|
|
|
CP0398752
|
(2R,4S)-N,N-dimethyl-4-[4-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C19H21ClF3N
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0535218
|
1-(2-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)urea
Show/Hide
|
C24H28ClN5O2
|
1
|
| 1 |
Ki = 223 nM
|
|
|
|
CP0383796
|
2-(2-methyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-1-ethanamine
Show/Hide
|
C14H18N2
|
1
|
| 1 |
Ki = 225 nM
|
|
|
|
CP0329114
|
N-[3-(2-methylpyrazol-3-yl)-4-(2-pyrrolidin-1-ylethoxy)phenyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C24H25F3N4O2
|
1
|
| 1 |
Ki = 225 nM
|
|
|
|
CP0398382
|
(2R,4S)-N,N-dimethyl-4-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C19H21ClF3N
|
1
|
| 1 |
Ki = 230 nM
|
|
|
|
CP0399957
|
4-chloro-2-[4-methoxy-3-(2-piperidin-1-ylethoxy)phenyl]-3H-isoindol-1-one
Show/Hide
|
C22H25ClN2O3
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0846938
|
1-(3-Acetylphenyl)-3-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]urea
Show/Hide
|
C20H19BrN4O3
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0887207
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-(4-chlorobenzyloxy)-phenyl]-3-(4-chlorophenyl)urea
Show/Hide
|
C24H19BrCl2N4O2
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0061062
|
6-(2-{2-[4-(4-Chloro-phenoxy)-piperidin-1-yl]-ethyl}-pyrrolidine-1-sulfonyl)-1H-indole; hydrochloride
Show/Hide
|
C25H30ClN3O3S
|
1
|
| 1 |
Ki = 269.15 nM
|
|
|
|
CP0386626
|
(2S,4S)-4-(2-chlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21Cl2N
|
1
|
| 1 |
Ki = 290 nM
|
|
|
|
CP0391904
|
3-(4-methylphenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
Show/Hide
|
C14H17N3
|
1
|
| 1 |
Ki = 296 nM
|
|
|
|
CP0388360
|
N-[3-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]-2-methylphenyl]-4-phenylbenzamide
Show/Hide
|
C29H28ClN5O2
|
1
|
| 1 |
Ki = 302 nM
|
|
|
|
CP0453550
|
5-(dimethylamino)-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C16H18N4O
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0509936
|
5-bromo-7-nitro-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C14H11BrN4O3
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0535073
|
5-nitro-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C14H12N4O3
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0866949
|
1-[3-(4-Chloro-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
Show/Hide
|
C18H15ClF2N4O2
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0845072
|
(cyclo[(6-bromo-8-entryptophan)arginine])
Show/Hide
|
C17H19BrN6O2
|
1
|
| 1 |
Ki = 340 nM
|
|
|
|
CP0397115
|
1-(4-methoxyphenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)urea
Show/Hide
|
C25H31N5O3
|
1
|
| 1 |
Ki = 385 nM
|
|
|
|
CP0183577
|
5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid ((S)-3-hexahydro-pyrrolo[1,2-a]pyrazin-2-yl-4-methoxy-phenyl)-amide
Show/Hide
|
C23H26ClN3O3S2
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0861232
|
3-Cyclopentyl-N-(2-dimethylamino-ethyl)-N-[4'-(phenethylamino-methyl)-biphenyl-4-ylmethyl]-propionamide with di TFA
Show/Hide
|
C38H47F6N3O5
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0378902
|
1-(3,4-dichlorophenyl)-3-[6-(pyridin-2-ylmethoxy)pyridin-3-yl]imidazolidin-2-one
Show/Hide
|
C20H16Cl2N4O2
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0852993
|
1-(3,4-Difluorophenyl)-3-[3-(4-fluoro-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]urea
Show/Hide
|
C18H15F3N4O2
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0887362
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2-fluorophenyl)urea
Show/Hide
|
C18H16BrFN4O2
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0917365
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(4-dimethylaminophenyl)urea
Show/Hide
|
C20H22BrN5O2
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0430982
|
1-(3-methoxyphenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)urea
Show/Hide
|
C25H31N5O3
|
1
|
| 1 |
Ki = 403 nM
|
|
|
|
CP0204186
|
1-(3-(4-chloro-1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)-3-(2,4-difluorophenyl)urea
Show/Hide
|
C23H24ClF2N5O3
|
1
|
| 1 |
Ki = 405 nM
|
|
|
|
CP0900317
|
1-Benzo[b]thiophen-5-yl-3-(3-methyl-isothiazol-5-yl)-urea
Show/Hide
|
C13H11N3OS2
|
1
|
| 1 |
Ki = 416.87 nM
|
|
|
|
CP0386622
|
trans-H2-PAT(+)
Show/Hide
|
C18H21N
|
1
|
| 1 |
Ki = 430 nM
|
|
|
|
CP0457525
|
1-(4-fluorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)urea
Show/Hide
|
C24H28FN5O2
|
1
|
| 1 |
Ki = 466 nM
|
|
|
|
CP0400567
|
1-(4-chlorophenyl)-3-(4-(2-((2R,6S)-2,6-dimethylpiperidin-1-yl)ethoxy)-3-(1-methyl-1H-pyrazol-5-yl)phenyl)urea
Show/Hide
|
C26H32ClN5O2
|
1
|
| 1 |
Ki = 481 nM
|
|
|
|
CP0503986
|
4-chloro-N-pyridin-3-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C14H12ClN3O
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0113176
|
5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
Show/Hide
|
C21H24ClN3O3S2
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0398378
|
(2S,4R)-N,N-dimethyl-4-[4-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C19H21ClF3N
|
1
|
| 1 |
Ki = 520 nM
|
|
|
|
CP0307921
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H26FN3O3S2
|
1
|
| 1 |
Ki = 540 nM
|
|
|
|
CP0165719
|
N-[3-[(8aR)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-4-methoxyphenyl]-5-chloro-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H26ClN3O3S2
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0853819
|
(E)-N-(2-Dimethylamino-ethyl)-N-[4'-(phenethylamino-methyl)-biphenyl-4-ylmethyl]-3-phenyl-acrylamide TFA
Show/Hide
|
C37H40F3N3O3
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0504137
|
7-[4-[2-(4-fluorophenyl)ethyl]piperazine-1-carbonyl]-1H-indole-3-carbonitrile
Show/Hide
|
C22H21FN4O
|
1
|
| 1 |
Ki = 645 nM
|
|
|
|
CP0473953
|
1-(3-fluorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)urea
Show/Hide
|
C24H28FN5O2
|
1
|
| 1 |
Ki = 760 nM
|
|
|
|
CP0391908
|
3-(4-fluorophenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
Show/Hide
|
C13H13FN2O
|
1
|
| 1 |
Ki = 785 nM
|
|
|
|
CP0405380
|
6,7-Dichloro-2,3-dihydro-indole-1-carboxylic acid pyridin-3-ylamide
Show/Hide
|
C14H11Cl2N3O
|
2
|
| 1 |
Ki = 794 nM
|
|
|
| 2 |
Ki = 794.33 nM
|
|
|
|
CP0852976
|
1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-phenethyloxyphenyl]-3-(4-chlorophenyl)urea
Show/Hide
|
C25H22BrClN4O2
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0391901
|
3-(4-chlorophenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
Show/Hide
|
C13H14ClN3
|
1
|
| 1 |
Ki = 799 nM
|
|
|
|
CP0518738
|
(2R,4S)-4-cyclooctyl-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C20H32ClN
|
1
|
| 1 |
Ki = 800 nM
|
|
|
|
CP0506482
|
1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-3-(4-hydroxyphenyl)urea
Show/Hide
|
C23H26BrN5O3
|
1
|
| 1 |
Ki = 810 nM
|
|
|
|
CP0185590
|
4-Bromo-N-[4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-benzenesulfonamide
Show/Hide
|
C18H22BrN3O3S
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0198069
|
(R)-4-Methyl-1-(2-(1-(naphthalene-1-sulfonyl)-pyrrolidin-2-yl)-ethyl)-piperidine(10)
Show/Hide
|
C22H30N2O2S
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0847634
|
(E)-N-[4'-(Phenethylamino-methyl)-biphenyl-4-ylmethyl]-3-phenyl-N-pyridin-3-ylmethyl-acrylamide TFA
Show/Hide
|
C39H36F3N3O3
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0398755
|
(2R,4S)-N,N-dimethyl-4-(3-phenylphenyl)-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C24H26ClN
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0428879
|
(2R,4S)-N,N-dimethyl-4-(4-nitrophenyl)-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C18H21ClN2O2
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0473952
|
1-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-phenylurea
Show/Hide
|
C24H29N5O2
|
1
|
| 1 |
Ki = 1090 nM
|
|
|
|
CP0391907
|
3-(4-chlorophenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
Show/Hide
|
C13H13ClN2O
|
1
|
| 1 |
Ki = 1099 nM
|
|
|
|
CP0446627
|
N-[3-(2-methylpyrazol-3-yl)-4-(2-pyrrolidin-1-ylethoxy)phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C24H25F3N4O2
|
1
|
| 1 |
Ki = 1140 nM
|
|
|
|
CP0509815
|
1-(2-fluorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)urea
Show/Hide
|
C24H28FN5O2
|
1
|
| 1 |
Ki = 1150 nM
|
|
|
|
CP0400569
|
1-(2,4-difluorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-yl)ethoxy)phenyl)urea
Show/Hide
|
C24H27F2N5O2
|
1
|
| 1 |
Ki = 1170 nM
|
|
|
|
CP0317110
|
1-(3-fluorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)urea
Show/Hide
|
C23H26FN5O3
|
1
|
| 1 |
Ki = 1230 nM
|
|
|
|
CP0418457
|
2,3-Dihydro-indole-1-carboxylic acid pyridin-3-ylamide
Show/Hide
|
C14H13N3O
|
2
|
| 1 |
Ki = 1258.93 nM
|
|
|
| 2 |
Ki = 1259 nM
|
|
|
|
CP0170807
|
5-chloro-3-ethyl-N-(4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H23ClN4O2S2
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0208303
|
5-chloro-2-methyl-N-(4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-3-sulfonamide
Show/Hide
|
C22H21ClN4O2S2
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0296883
|
7-fluoro-6-[[1-[2-(7-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H27F2N3O3
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0485732
|
1-(3-fluorophenyl)-3-[3-(2-hydroxyethoxy)-4-methoxyphenyl]imidazolidin-2-one
Show/Hide
|
C18H19FN2O4
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0038617
|
2-[4-(4-Chloro-1-methyl-1H-pyrazole-3-carbonyl)piperazin-1-yl]-1-(4-fluorophenyl)ethanone
Show/Hide
|
C17H18ClFN4O2
|
1
|
| 1 |
Ki = 1410 nM
|
|
|
|
CP0504136
|
1-(4-Fluorophenyl)-2-[4-(1-methyl-1H-pyrazole-3-carbonyl)-piperazin-1-yl]ethanone
Show/Hide
|
C17H19FN4O2
|
1
|
| 1 |
Ki = 1420 nM
|
|
|
|
CP0388361
|
N-[3-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]-2-methylphenyl]-4-(6-methoxypyridin-3-yl)benzamide
Show/Hide
|
C29H29ClN6O3
|
1
|
| 1 |
Ki = 1548.82 nM
|
|
|
|
CP0398381
|
(2S,4R)-N,N-dimethyl-4-(2-methylphenyl)-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C19H24ClN
|
1
|
| 1 |
Ki = 1600 nM
|
|
|
|
CP0941206
|
Paynantheine
Show/Hide
|
C23H28N2O4
|
1
|
| 1 |
Ki = 1770 nM
|
|
|
|
CP0674190
|
5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid (4-methoxy-3-piperazin-1-yl-phenyl)-amide hydrochloride
Show/Hide
|
C20H23Cl2N3O3S2
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0244136
|
N-(2-fluoro-5-pyridin-3-ylphenyl)-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C22H17F4N3O2
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0041243
|
5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-methyl-1-benzothiophene-2-sulfonamide hydrochloride
Show/Hide
|
C20H22ClN3O3S2
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0398380
|
(2R,4S)-N,N-dimethyl-4-(2-methylphenyl)-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
Show/Hide
|
C19H24ClN
|
1
|
| 1 |
Ki = 2000 nM
|
|
|
|
CP0377040
|
(E)-5-[(6-Fluoro-1H-indol-3-yl)methylene]-2-imino-1,3-dimethylimidazolidin-4-one
Show/Hide
|
C14H13FN4O
|
1
|
| 1 |
Ki = 2114 nM
|
|
|
|
CP0422007
|
2-[4-(4-Bromo-1-methyl-1H-pyrazole-3-carbonyl)piperazin-1-yl]-1-(4-fluorophenyl)ethanone
Show/Hide
|
C17H18BrFN4O2
|
1
|
| 1 |
Ki = 2120 nM
|
|
|
|
CP0055735
|
5-(6-Bromo-1H-indol-3-ylmethylene)-2-imino-1,3-dimethyl-imidazolidin-4-one
Show/Hide
|
C14H13BrN4O
|
1
|
| 1 |
Ki = 2202 nM
|
|
|
|
CP0522073
|
N-[4-(2-aminoethoxy)-3-(2-methylpyrazol-3-yl)phenyl]-3-methoxybenzamide
Show/Hide
|
C20H22N4O3
|
1
|
| 1 |
Ki = 2347 nM
|
|
|
|
CP0082421
|
5-chloro-3-methyl-N-(2-methyl-4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H23ClN4O2S2
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0035199
|
5-fluoro-6-[[1-[2-(7-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H27F2N3O3
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0332841
|
6-[[1-[2-(7-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-8-fluoro-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H27ClFN3O3
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0099712
|
3-(2-aminoethyl)-1H-indole-5-carboxamide
Show/Hide
|
C11H13N3O
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0422010
|
2-[4-(4-Chloro-1H-pyrazole-3-carbonyl)piperazin-1-yl]-1-(4-fluorophenyl)ethanone
Show/Hide
|
C16H16ClFN4O2
|
1
|
| 1 |
Ki = 2750 nM
|
|
|
|
CP0428411
|
N-[2-methyl-3-[(6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]phenyl]-4-phenylbenzamide
Show/Hide
|
C29H29N5O2
|
1
|
| 1 |
Ki = 2818.38 nM
|
|
|
|
CP0093940
|
(4-Bromo-1-methyl-1H-pyrazol-3-yl)-{4-[2-(2,4-difluorophenyl)-ethyl]piperazin-1-yl}methanone
Show/Hide
|
C17H19BrF2N4O
|
1
|
| 1 |
Ki = 2820 nM
|
|
|
|
CP0488639
|
2-[4-(4-Bromo-1,5-dimethyl-1H-pyrazole-3-carbonyl)piperazin-1-yl]-1-(4-fluorophenyl)ethanone
Show/Hide
|
C18H20BrFN4O2
|
1
|
| 1 |
Ki = 2933 nM
|
|
|
|
CP0400087
|
N-[3-(4-chloro-2-methylpyrazol-3-yl)-4-(2-morpholin-4-ylethoxy)phenyl]-3-fluorobenzamide
Show/Hide
|
C23H24ClFN4O3
|
1
|
| 1 |
Ki = 3380 nM
|
|
|
|
CP0422011
|
US9434692, 52
Show/Hide
|
C17H18BrFN4O2
|
1
|
| 1 |
Ki = 3573 nM
|
|
|
|
CP0464613
|
1-(4-Fluorophenyl)-2-[4-(5-methyl-2-phenyl-2H-pyrazole-3-carbonyl)piperazin-1-yl]ethanone
Show/Hide
|
C23H23FN4O2
|
1
|
| 1 |
Ki = 3714 nM
|
|
|
|
CP0467469
|
1-(4-Fluorophenyl)-2-[4-(1-methyl-5-trifluoromethyl-1H-pyrazole-3-carbonyl)piperazin-1-yl]ethanone
Show/Hide
|
C18H18F4N4O2
|
1
|
| 1 |
Ki = 3866 nM
|
|
|
|
CP0504139
|
1-(4-Fluorophenyl)-2-[4-(4-iodo-1-methyl-1H-pyrazole-3-carbonyl)piperazin-1-yl]ethanone
Show/Hide
|
C17H18FIN4O2
|
1
|
| 1 |
Ki = 3866 nM
|
|
|
|
CP0295528
|
6-[[1-[2-(7-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-5-fluoro-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H27ClFN3O3
|
1
|
| 1 |
Ki = 3981.07 nM
|
|
|
|
CP0904783
|
1-Methyl-1,6,7,8-tetrahydro-pyrrolo[2,3-g]quinoline-5-carboxylic acid pyridin-3-ylamide
Show/Hide
|
C18H18N4O
|
1
|
| 1 |
Ki = 4073.8 nM
|
|
|
|
CP0422005
|
(4-Bromo-1-methyl-1Hpyrazol-3-yl)-{4-[2-(4-fluorophenyl)ethyl]piperazin-1-yl}methanone
Show/Hide
|
C17H20BrFN4O
|
1
|
| 1 |
Ki = 4146 nM
|
|
|
|
CP0372923
|
2-[3-[(2S,5S)-5-[(6-bromo-1H-indol-3-yl)methyl]-3,6-dioxopiperazin-2-yl]propyl]guanidine
Show/Hide
|
C17H21BrN6O2
|
1
|
| 1 |
Ki = 4630 nM
|
|
|
|
CP0377031
|
(E)-3-Ethyl-5-[(6-fluoro-1H-indol-3-yl)methylene]-2-imino-1methylimidazolidin-4-one
Show/Hide
|
C15H15FN4O
|
1
|
| 1 |
Ki = 5230 nM
|
|
|
|
CP0915741
|
Speciogynine
Show/Hide
|
C23H30N2O4
|
1
|
| 1 |
Ki = 5430 nM
|
|
|
|
CP0288558
|
N-[4-[2-(4-acetylpiperazin-1-yl)ethoxy]-3-(2-methylpyrazol-3-yl)phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C26H28F3N5O3
|
1
|
| 1 |
Ki = 5614 nM
|
|
|
|
CP0467472
|
2-[4-(4-Bromo-1-methyl-1H-pyrazole-3-carbonyl)piperazin-1-yl]-1-(4-trifluoromethoxyphenyl)ethanone
Show/Hide
|
C18H18BrF3N4O3
|
1
|
| 1 |
Ki = 5614 nM
|
|
|
|
CP0507243
|
N-[4-[2-(2-hydroxyethylamino)ethoxy]-3-(2-methylpyrazol-3-yl)phenyl]-3-methoxybenzamide
Show/Hide
|
C22H26N4O4
|
1
|
| 1 |
Ki = 5874 nM
|
|
|
|
CP0501873
|
4-{2-[4-(3-Methoxy-benzoylamino)-2-(2-methyl-2H-pyrazol-3-yl)-phenoxy]-ethyl}-piperazine-1-carboxylicAcid Amide
Show/Hide
|
C25H30N6O4
|
1
|
| 1 |
Ki = 5890 nM
|
|
|
|
CP0501999
|
N-[3-(2-methylpyrazol-3-yl)-4-(2-morpholin-4-ylethoxy)phenyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C24H25F3N4O3
|
1
|
| 1 |
Ki = 5900 nM
|
|
|
|
CP0377014
|
(Z)-5-((1H-Indol-3yl)methylene)-3-ethyl-2-imino-1-methylimidazolidin-4-one
Show/Hide
|
C15H16N4O
|
1
|
| 1 |
Ki = 8323 nM
|
|
|
|
CP0502000
|
N-[4-[2-(4-acetylpiperazin-1-yl)ethoxy]-3-(4-chloro-2-methylpyrazol-3-yl)phenyl]-3-fluorobenzamide
Show/Hide
|
C25H27ClFN5O3
|
1
|
| 1 |
Ki = 8600 nM
|
|
|
|
CP0535116
|
2-[4-(4-Bromo-1-methyl-1H-pyrazole-3-carbonyl)piperazin-1-yl]-1-(4-fluorophenyl)ethanone O-Methyloxime
Show/Hide
|
C18H21BrFN5O2
|
1
|
| 1 |
Ki = 8600 nM
|
|
|
|
CP0438786
|
N-[4-[2-(3,3-difluoropyrrolidin-1-yl)ethoxy]-3-(2-methylpyrazol-3-yl)phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C24H23F5N4O2
|
1
|
| 1 |
Ki = 9250 nM
|
|
|
|
CP0502296
|
2-[4-(4-Bromo-1-methyl-1H-pyrazole-3-carbonyl)piperazin-1-yl]-1-(2-fluorophenyl)ethanone
Show/Hide
|
C17H18BrFN4O2
|
1
|
| 1 |
Ki = 9800 nM
|
|
|
|
CP0071244
|
4-(6-methoxypyridin-3-yl)-N-[2-methyl-3-[(6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]phenyl]benzamide
Show/Hide
|
C29H30N6O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0336115
|
3-Methoxy-N-[3-(2-methyl-2H-pyrazol-3-yl)-4-(2-morpholin-4-yl-ethoxy)-phenyl]-benzamide
Show/Hide
|
C24H28N4O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0417094
|
3-Methoxy-N-{3-(1-methyl-1H-pyrazol-5-yl)-4-[2-(4-(methylsulfonyl)piperazin-1-yl)ethoxy]phenyl}benzamide
Show/Hide
|
C25H31N5O5S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0417798
|
4-Fluoro-N-[3-(2-methyl-2H-pyrazol-3-yl)-4-(2-morpholin-4-ylethoxy)-phenyl]-benzamide
Show/Hide
|
C23H25FN4O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0417800
|
3,4-Difluoro-N-[3-(2-methyl-2H-pyrazol-3-yl)-4-(2-morpholin-4-yl-ethoxy)-phenyl]-benzamide
Show/Hide
|
C23H24F2N4O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0446628
|
3-Fluoro-N-[3-(2-methyl-2H-pyrazol-3-yl)-4-(2-morpholin-4-ylethoxy)-phenyl]-benzamide
Show/Hide
|
C23H25FN4O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0452155
|
N-[3-(2-methylpyrazol-3-yl)-4-[2-(3-oxopiperazin-1-yl)ethoxy]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C24H24F3N5O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0452156
|
2,4-Difluoro-N-[3-(2-Methyl-2H-pyrazol-3-yl)-4-(2-morpholin-4-yl-ethoxy)-phenyl]-benzamide
Show/Hide
|
C23H24F2N4O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0490909
|
N-[4-[2-(4-acetylpiperazin-1-yl)ethoxy]-3-(2-methylpyrazol-3-yl)phenyl]-3-methoxybenzamide
Show/Hide
|
C26H31N5O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0507242
|
N-[4-[2-(4-acetylpiperazin-1-yl)ethoxy]-3-(2-methylpyrazol-3-yl)phenyl]-3-fluorobenzamide
Show/Hide
|
C25H28FN5O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0507244
|
N-[3-(2-methylpyrazol-3-yl)-4-(2-morpholin-4-ylethoxy)phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C24H25F3N4O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0518444
|
N-[3-(4-chloro-2-methylpyrazol-3-yl)-4-[2-(3-oxopiperazin-1-yl)ethoxy]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C24H23ClF3N5O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0388108
|
(4-Bromo-1-methyl-1H-pyrazol-3-yl)-{4-[2-(4-fluorophenyl)-2-hydroxyethyl]piperazin-1-yl}methanone
Show/Hide
|
C17H20BrFN4O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0388109
|
(4-Bromo-1-methyl-1H-pyrazol-3-yl)-{4-[2-(3-fluorophenyl)ethyl]-piperazin-1-yl}methanone
Show/Hide
|
C17H20BrFN4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0388110
|
(4-Bromo-1-methyl-1H-pyrazol-3-yl)-{4-[2-(4-chlorophenyl)-ethyl]piperazin-1-yl}methanone
Show/Hide
|
C17H20BrClN4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0416369
|
2-[4-(1,5-Dimethyl-1H-pyrazole-3-carbonyl)piperazin-1-yl]-1-(4-fluorophenyl)ethanone
Show/Hide
|
C18H21FN4O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0422006
|
(4-Bromo-1-methyl-1H-pyrazol-3-yl)-(4-phenethylpiperazin-1-yl)methanone
Show/Hide
|
C17H21BrN4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0422008
|
2-[4-(4-Bromo-1-methyl-1H-pyrazole-3-carbonyl)piperazin-1-yl]-1-(2,4-difluorophenyl)ethanone
Show/Hide
|
C17H17BrF2N4O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0422012
|
2-[4-(1-tert-Butyl-5-methyl-1H-pyrazole-3-carbonyl)piperazin-1-yl]-1-(4-fluorophenyl)ethanone
Show/Hide
|
C21H27FN4O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0467468
|
2-{2-[4-(4-Bromo-1-methyl-1H-pyrazole-3-carbonyl)piperazin-1-yl]ethyl}isoindoline-1,3-dione
Show/Hide
|
C19H20BrN5O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0467471
|
N-[3-(4-chloro-2-methylpyrazol-3-yl)-4-methoxyphenyl]-4-[2-(4-fluorophenyl)ethyl]piperazine-1-carboxamide
Show/Hide
|
C24H27ClFN5O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0476455
|
3-{2-[4-(4-Bromo-1-methyl-1H-pyrazole-3-carbonyl)piperazin-1-yl]ethyl}-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C20H27BrN6O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0488632
|
(4-Bromo-1-methyl-1H-pyrazol-3-yl)-{4-[2-(4-methoxyphenyl)-ethyl]piperazin-1-yl}methanone
Show/Hide
|
C18H23BrN4O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0488640
|
2-[4-(4-Chloro-1-ethyl-1H-pyrazole-3-carbonyl)piperazin-1-yl]-1-(4-fluorophenyl)ethanone
Show/Hide
|
C18H20ClFN4O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0488641
|
(4-Bromo-1-methyl-1Hpyrazol-3-yl)-{4-[2-(2-fluorophenyl)ethyl]piperazin-1-yl}methanone
Show/Hide
|
C17H20BrFN4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0513532
|
N-(4-bromo-1H-pyrazol-5-yl)-4-[2-(4-fluorophenyl)ethyl]piperazine-1-carboxamide
Show/Hide
|
C16H19BrFN5O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0514844
|
1-(4-Fluorophenyl)-2-[4-(5-methyl-2H-pyrazole-3-carbonyl)-piperazin-1-yl]ethanone
Show/Hide
|
C17H19FN4O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0520882
|
2-[4-(4-Bromo-1-methyl-1H-pyrazole-3-carbonyl)piperazin-1-yl]-1-(4-trifluoromethylphenyl)ethanone
Show/Hide
|
C18H18BrF3N4O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0135923
|
CHEBI:6956
Show/Hide
|
C23H30N2O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0312260
|
2-Dipropylamino-1,2,3,4-tetrahydro-naphthalene-1,8-diol
Show/Hide
|
C16H26N2O
|
1
|
| 1 |
Ki = 12589.25 nM
|
|
|
|
CP0253203
|
(E)-5-((1H-Indol-3yl)methylene)-2-imino-1,3-dimethylimidazolidin-4-one
Show/Hide
|
C14H14N4O
|
1
|
| 1 |
Ki = 14451 nM
|
|
|
|
CP0271460
|
(R)-1-(2-(1-(3,4-Dichloro-benzene sulfonyl)-pyrrolidin-2-yl)-ethyl)-4-methyl piperidine
Show/Hide
|
C18H26Cl2N2O2S
|
1
|
| 1 |
Ki < 1000 nM
|
|
|
|
CP0379280
|
2-[3-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]propoxy]benzamide
Show/Hide
|
C28H30N4O4S
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0081712
|
4-tert-butyl-N-(4-piperazin-1-ylquinolin-6-yl)benzenesulfonamide
Show/Hide
|
C23H28N4O2S
|
1
|
| 1 |
Ki < 1995.26 nM
|
|
|
|
CP0111551
|
5-chloro-N-(4-piperazin-1-ylquinolin-6-yl)naphthalene-2-sulfonamide
Show/Hide
|
C23H21ClN4O2S
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0173778
|
5-chloro-3-methyl-N-(4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-2-sulfonamide
Show/Hide
|
C22H21ClN4O2S2
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0216543
|
N-[3-(1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazin-2-yl)-4-methoxyphenyl]-5-chloro-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H28ClN3O3S2
|
1
|
| 1 |
Ki < 3162.28 nM
|
|
|
|
CP0343547
|
5-chloro-3-methyl-N-[4-[(3S)-3-methylpiperazin-1-yl]quinolin-6-yl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H23ClN4O2S2
|
1
|
| 1 |
Ki < 3981.07 nM
|
|
|
|
CP0051242
|
(R)-1-(2-(1-(3-bromo-benzenesulfonyl)-pyrrolidin-2-yl)-ethyl)-4-methyl piperidine
Show/Hide
|
C18H27BrN2O2S
|
1
|
| 1 |
Ki < 5011.87 nM
|
|
|
|
CP0182705
|
(R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidin-2-yl)-ethyl)-piperidine (Oxalate salt)
Show/Hide
|
C19H30N2O2S
|
1
|
| 1 |
Ki < 5011.87 nM
|
|
|
|
CP0306083
|
5-chloro-3-methyl-N-[4-(4-methylpiperazin-1-yl)quinolin-6-yl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H23ClN4O2S2
|
1
|
| 1 |
Ki < 5011.87 nM
|
|
|
|
CP0332842
|
6-[[1-[2-(7-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-7-fluoro-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H27ClFN3O3
|
1
|
| 1 |
Ki < 5011.87 nM
|
|
|
|
CP0399908
|
3-[4-[[3-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]-2-methylphenyl]carbamoyl]phenyl]benzamide
Show/Hide
|
C30H29ClN6O3
|
1
|
| 1 |
Ki > 6025.6 nM
|
|
|
|
CP0870822
|
3-Methyl-8,9-dihydro-3H,7H-pyrrolo[3,2-f]quinoline-6-carboxylic acid pyridin-3-ylamide
Show/Hide
|
C18H18N4O
|
1
|
| 1 |
Ki < 6309.57 nM
|
|
|
|
CP0152118
|
6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H29N3O3
|
1
|
| 1 |
Ki < 7943.28 nM
|
|
|
|
CP0096286
|
(R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidin-1-ylsulfonyl)phenol
Show/Hide
|
C18H28N2O3S
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
|
CP0712961
|
(R)-sulfonamide1-(4-methylhexahydro-1-pyridinyl)-2-[1-(1-naphthylsulfonyl)hexahydro-2-pyridinyl]ethane
Show/Hide
|
C23H32N2O2S
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
|
CP0658944
|
(RS)-1-(4-methylhexahydro-1-pyridinyl)-2-[1-(1-naphthylsulfonyl)hexahydro-2-pyridinyl]ethane
Show/Hide
|
C23H32N2O2S
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
|
CP0371948
|
8-fluoro-6-[[1-[2-(7-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H27F2N3O3
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
|
CP0156235
|
3,N-Dimethyl-N-[(R)-1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide
Show/Hide
|
C18H30N2O2S
|
1
|
| 1 |
Ki < 15848.93 nM
|
|
|
