General Information of the Compound
| Compound ID |
CP0171734
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| Compound Name |
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (4-chloro-3-pyridin-3-yl-phenyl)-amide
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| Structure |
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| Formula |
C22H17ClF3N3O2
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| Molecular Weight |
447.844
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| Canonical SMILES |
COc1cc2CCN(C(=O)Nc3ccc(Cl)c(c3)-c3cccnc3)c2cc1C(F)(F)F
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| InChI |
InChI=1S/C22H17ClF3N3O2/c1-31-20-9-13-6-8-29(19(13)11-17(20)22(24,25)26)21(30)28-15-4-5-18(23)16(10-15)14-3-2-7-27-12-14/h2-5,7,9-12H,6,8H2,1H3,(H,28,30)
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| InChIKey |
QODRLEBXZLZSBQ-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00825, 5-hydroxytryptamine receptor 2A
Protein ID: PT01019, 5-hydroxytryptamine receptor 2B
Protein ID: PT00939, 5-hydroxytryptamine receptor 2C