General Information of the Compound
| Compound ID |
CP0071447
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| Compound Name |
(1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
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| Synonyms |
(R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
10-chloro-2-methyl-4-azabicyclo[5.4.0]undeca-8,10,12-triene
APD 356
APD356
AR-10A
Lorcaserin
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| Structure |
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| Formula |
C11H14ClN
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| Molecular Weight |
195.693
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| Canonical SMILES |
C[C@H]1CNCCc2ccc(Cl)cc12
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| InChI |
InChI=1S/C11H14ClN/c1-8-7-13-5-4-9-2-3-10(12)6-11(8)9/h2-3,6,8,13H,4-5,7H2,1H3/t8-/m0/s1
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| InChIKey |
XTTZERNUQAFMOF-QMMMGPOBSA-N
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| CAS |
616202-92-7
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00825, 5-hydroxytryptamine receptor 2A
Protein ID: PT01019, 5-hydroxytryptamine receptor 2B
Cell-based Assay
Protein ID: PT00939, 5-hydroxytryptamine receptor 2C
Cell-based Assay
Clinical Information about the Compound