Brief Information of the Compound and Protein
Compound Name
5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-carboxylic acid pyridin-3-ylamide
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PubChem ID
CID: 5163
SID: 14898053
Canonical SMILES
Cn1ccc2cc3N(CCc3cc12)C(=O)Nc1cccnc1
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Compound Formula C17H16N4O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2C
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28335
Gene Name
HTR2C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
Ki = 2.8 nM
   TI
   LI
   LO
   TS
2
Ki = 10 nM
   TI
   LI
   LO
   TS
3
Ki = 12.59 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9.4 nM