Brief Information of the Compound and Protein
Compound Name
(R)-4-benzyl-6,6a,7,8,9,10-hexahydro-5H- pyrazino[1,2-a][1,7]naphthyridine
    Show/Hide
PubChem ID
CID: 134265735
Canonical SMILES
C(c1ccccc1)c1cncc2N3CCNC[C@H]3CCc12
    Show/Hide
Compound Formula C18H21N3
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2C
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28335
Gene Name
HTR2C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 0.631 nM
   TI
   LI
   LO
   TS
2
Ki = 0.5012 nM
   TI
   LI
   LO
   TS