| Compound ID |
Compound Name |
Compound Formula |
|
CP0044960
|
(1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-5-one
Show/Hide
|
C19H30O2
|
3
|
| 1 |
EC50 = 0.18 nM
|
|
|
| 2 |
IC50 = 2.1 nM
|
|
|
| 3 |
IC50 = 2.6 nM
|
|
|
|
CP0035660
|
4-(((6-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino)methyl)benzoic acid
Show/Hide
|
C28H24Cl2F3N3O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0093217
|
3-(((6-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino)methyl)benzoic acid
Show/Hide
|
C28H22Cl2F3N3O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0195439
|
4-(((6-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino)methyl)benzoic acid
Show/Hide
|
C28H22Cl2F3N3O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0372562
|
2-chloro-4-[4-[(4-fluorophenyl)methyl]-3,5-dimethylpyrazol-1-yl]benzonitrile
Show/Hide
|
C19H15ClFN3
|
1
|
| 1 |
IC50 = 0.47 nM
|
|
|
|
CP0392728
|
1-benzyl-4-(4-cyanophenyl)-2,5-dimethylpyrrole-3-carbonitrile
Show/Hide
|
C21H17N3
|
2
|
| 1 |
IC50 = 1.4 nM
|
|
|
| 2 |
IC50 = 3 nM
|
|
|
|
CP0372488
|
4-[4-[(4-fluorophenyl)methyl]-3,5-dimethylpyrazol-1-yl]-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C20H15F4N3
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0392437
|
1-benzyl-2,5-dimethyl-3-(4-nitrophenyl)pyrrole
Show/Hide
|
C19H18N2O2
|
2
|
| 1 |
IC50 = 2.2 nM
|
|
|
| 2 |
IC50 = 6.7 nM
|
|
|
|
CP0392737
|
4-(4-cyanophenyl)-2,5-dimethyl-1-(pyridin-3-ylmethyl)pyrrole-3-carbonitrile
Show/Hide
|
C20H16N4
|
2
|
| 1 |
IC50 = 3.4 nM
|
|
|
| 2 |
IC50 = 23 nM
|
|
|
|
CP0398339
|
methyl 1-benzyl-2,5-dimethyl-4-(4-nitrophenyl)pyrrole-3-carboxylate
Show/Hide
|
C21H20N2O4
|
2
|
| 1 |
IC50 = 3.8 nM
|
|
|
| 2 |
IC50 = 5 nM
|
|
|
|
CP0217093
|
Enobosarm
Show/Hide
|
C19H14F3N3O3
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0392731
|
methyl 1-benzyl-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-dimethylpyrrole-3-carboxylate
Show/Hide
|
C23H19F3N2O2
|
2
|
| 1 |
IC50 = 3.9 nM
|
|
|
| 2 |
IC50 = 4.7 nM
|
|
|
|
CP0392430
|
ethyl 1-benzyl-2,5-dimethyl-4-(4-nitrophenyl)pyrrole-3-carboxylate
Show/Hide
|
C22H22N2O4
|
2
|
| 1 |
IC50 = 5.2 nM
|
|
|
| 2 |
IC50 = 5.5 nM
|
|
|
|
CP0392434
|
1-[(6-chloropyridin-3-yl)methyl]-4-(4-cyanophenyl)-2,5-dimethylpyrrole-3-carbonitrile
Show/Hide
|
C20H15ClN4
|
2
|
| 1 |
IC50 = 9 nM
|
|
|
| 2 |
IC50 = 24 nM
|
|
|
|
CP0392736
|
4-(4-cyanophenyl)-1-[[5-(hydroxymethyl)pyridin-3-yl]methyl]-2,5-dimethylpyrrole-3-carbonitrile
Show/Hide
|
C21H18N4O
|
2
|
| 1 |
IC50 = 14 nM
|
|
|
| 2 |
IC50 = 150 nM
|
|
|
|
CP0382456
|
4-[[1-(3-chloro-4-cyanophenyl)-3,5-dimethylpyrazol-4-yl]methyl]benzamide
Show/Hide
|
C20H17ClN4O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0071636
|
956104-40-8
Show/Hide
|
C21H15F4N5O2S
|
2
|
| 1 |
IC50 = 16 nM
|
|
|
| 2 |
IC50 = 160 nM
|
|
|
|
CP0391873
|
ethyl 2,5-dimethyl-4-(4-nitrophenyl)-1H-pyrrole-3-carboxylate
Show/Hide
|
C15H16N2O4
|
2
|
| 1 |
IC50 = 22 nM
|
|
|
| 2 |
IC50 = 34 nM
|
|
|
|
CP0457167
|
methyl 1-benzyl-4-(4-cyanophenyl)-2,5-dimethylpyrrole-3-carboxylate
Show/Hide
|
C22H20N2O2
|
2
|
| 1 |
IC50 = 23 nM
|
|
|
| 2 |
IC50 = 27 nM
|
|
|
|
CP0456774
|
2-chloro-4-[4-[(4-fluorophenyl)-hydroxymethyl]-3,5-dimethylpyrazol-1-yl]benzonitrile
Show/Hide
|
C19H15ClFN3O
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0382660
|
4-[[1-(3-chloro-4-cyanophenyl)-3,5-dimethylpyrazol-4-yl]methyl]-N-methylbenzamide
Show/Hide
|
C21H19ClN4O
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0390361
|
ethyl 1,2,5-trimethyl-4-(4-nitrophenyl)pyrrole-3-carboxylate
Show/Hide
|
C16H18N2O4
|
2
|
| 1 |
IC50 = 30 nM
|
|
|
| 2 |
IC50 = 47 nM
|
|
|
|
CP0244334
|
(2S)-N-(3-chloro-4-cyanophenyl)-3-(5,6-difluoro-2,3-dihydroindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C19H16ClF2N3O2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0244661
|
(2S)-3-(4-bromo-3-fluoropyrazol-1-yl)-N-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-2-hydroxy-2-methylpropanamide
Show/Hide
|
C14H10BrF4N5O2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0528320
|
US10806720, Compound 1036
Show/Hide
|
C15H12F3N5O4
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0392734
|
1-[[6-chloro-5-(hydroxymethyl)pyridin-3-yl]methyl]-4-(4-cyanophenyl)-2,5-dimethylpyrrole-3-carbonitrile
Show/Hide
|
C21H17ClN4O
|
2
|
| 1 |
IC50 = 37 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0474159
|
(2S)-N-(3-chloro-4-cyanophenyl)-3-(6-fluoro-2,3-dihydroindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C19H17ClFN3O2
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0157500
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(6-fluoro-2,3-dihydroindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C20H17F4N3O2
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0479796
|
(2S)-N-(3-chloro-4-cyanophenyl)-3-(3-fluoroindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C19H15ClFN3O2
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0498409
|
(2S)-3-(4-cyanopyrazol-1-yl)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
Show/Hide
|
C16H12F3N5O2
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0337616
|
(2S)-3-(4-cyano-N-methyl-3-phenylanilino)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
Show/Hide
|
C26H21F3N4O2
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0391733
|
ethyl 2,5-dimethyl-4-(4-nitrophenyl)-1-(2-phenylethyl)pyrrole-3-carboxylate
Show/Hide
|
C23H24N2O4
|
2
|
| 1 |
IC50 = 52 nM
|
|
|
| 2 |
IC50 = 150 nM
|
|
|
|
CP0382659
|
2-chloro-4-[4-[2-(4-fluorophenyl)ethyl]-3,5-dimethylpyrazol-1-yl]benzonitrile
Show/Hide
|
C20H17ClFN3
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0146696
|
Bicalutamide
Show/Hide
|
C18H14F4N2O4S
|
3
|
| 1 |
IC50 = 54 nM
|
|
|
| 2 |
IC50 = 120 nM
|
|
|
| 3 |
IC50 = 248 nM
|
|
|
|
CP0167963
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-3-(6-nitroindol-1-yl)propanamide
Show/Hide
|
C20H15F3N4O4
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0234519
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluoro-2,3-dihydroindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C20H17F4N3O2
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0426269
|
(2S)-3-(4-cyanopyrazol-1-yl)-N-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-2-hydroxy-2-methylpropanamide
Show/Hide
|
C15H11F3N6O2
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0392738
|
ethyl 1-(benzenesulfonyl)-2,5-dimethyl-4-(4-nitrophenyl)pyrrole-3-carboxylate
Show/Hide
|
C21H20N2O6S
|
2
|
| 1 |
IC50 = 62 nM
|
|
|
| 2 |
IC50 = 130 nM
|
|
|
|
CP0252157
|
US10806720, Compound 1022
Show/Hide
|
C14H11F4N5O2
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0552835
|
5-[4-oxo-1-(1-oxo-3H-2-benzofuran-5-yl)-2-sulfanylidene-1,3-diazaspiro[4.4]nonan-3-yl]-3-(trifluoromethyl)pyridine-2-carbonitrile
Show/Hide
|
C22H15F3N4O3S
|
1
|
| 1 |
IC50 = 63.8 nM
|
|
|
|
CP0330137
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-3-indol-1-yl-2-methylpropanamide
Show/Hide
|
C20H16F3N3O2
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0392431
|
methyl 1-benzyl-2,5-dimethyl-4-phenylpyrrole-3-carboxylate
Show/Hide
|
C21H21NO2
|
2
|
| 1 |
IC50 = 65 nM
|
|
|
| 2 |
IC50 = 130 nM
|
|
|
|
CP0037494
|
(2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1,7-thieno[2,3-b]thiopyran-6-sulfonamide
Show/Hide
|
C10H16N2O4S3
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0317487
|
US10806720, Compound 1017
Show/Hide
|
C16H12F6N4O2
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0398340
|
1-[[6-chloro-5-(hydroxymethyl)pyridin-3-yl]methyl]-4-(4-cyanophenyl)-2-methylpyrrole-3-carbonitrile
Show/Hide
|
C20H15ClN4O
|
2
|
| 1 |
IC50 = 78 nM
|
|
|
| 2 |
IC50 = 160 nM
|
|
|
|
CP0558273
|
4-[4-oxo-1-(1-oxo-3H-2-benzofuran-5-yl)-2-sulfanylidene-1,3-diazaspiro[4.4]nonan-3-yl]-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C23H16F3N3O3S
|
1
|
| 1 |
IC50 = 80.7 nM
|
|
|
|
CP0348356
|
US10806720, Compound 1058
Show/Hide
|
C15H11BrF4N4O2
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0392435
|
ethyl 1-benzoyl-2,5-dimethyl-4-(4-nitrophenyl)pyrrole-3-carboxylate
Show/Hide
|
C22H20N2O5
|
2
|
| 1 |
IC50 = 85 nM
|
|
|
| 2 |
IC50 = 150 nM
|
|
|
|
CP0205324
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(5-fluoroindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C20H15F4N3O2
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0422584
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(6-fluoroindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C20H15F4N3O2
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0350663
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-3-(5-nitroindol-1-yl)propanamide
Show/Hide
|
C20H15F3N4O4
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0400678
|
4-[4-[(4-fluorophenyl)methyl]-3,5-dimethylpyrazol-1-yl]benzonitrile
Show/Hide
|
C19H16FN3
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
|
CP0390363
|
[1-benzyl-2,5-dimethyl-4-(4-nitrophenyl)pyrrol-3-yl]methanol
Show/Hide
|
C20H20N2O3
|
2
|
| 1 |
IC50 = 92 nM
|
|
|
| 2 |
IC50 = 300 nM
|
|
|
|
CP0553187
|
5-[4-oxo-1-(1-oxo-3H-2-benzofuran-5-yl)-2-sulfanylidene-1,3-diazaspiro[4.5]decan-3-yl]-3-(trifluoromethyl)pyridine-2-carbonitrile
Show/Hide
|
C23H17F3N4O3S
|
1
|
| 1 |
IC50 = 93.3 nM
|
|
|
|
CP0234495
|
(2S)-N-(3-chloro-4-cyanophenyl)-3-(5-fluoroindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C19H15ClFN3O2
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0424995
|
4-[4-oxo-1-(1-oxo-3H-2-benzofuran-5-yl)-2-sulfanylidene-1,3-diazaspiro[4.5]decan-3-yl]-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C24H18F3N3O3S
|
1
|
| 1 |
IC50 = 95.2 nM
|
|
|
|
CP0350686
|
(2S)-N-(3-chloro-4-cyanophenyl)-3-(6-fluoroindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C19H15ClFN3O2
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
|
CP0205322
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(5,6-difluoro-2,3-dihydroindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C20H16F5N3O2
|
1
|
| 1 |
IC50 = 101 nM
|
|
|
|
CP0397142
|
2-chloro-4-[4-(4-fluorophenoxy)-3,5-dimethylpyrazol-1-yl]benzonitrile
Show/Hide
|
C18H13ClFN3O
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0397143
|
N-tert-butyl-4-[[1-(3-chloro-4-cyanophenyl)-3,5-dimethylpyrazol-4-yl]methyl]benzamide
Show/Hide
|
C24H25ClN4O
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0095953
|
ENZALUTAMIDE
Show/Hide
|
C21H16F4N4O2S
|
5
|
| 1 |
IC50 = 112.3 nM
|
|
|
| 2 |
IC50 = 216 nM
|
|
|
| 3 |
IC50 = 450 nM
|
|
|
| 4 |
IC50 = 492 nM
|
|
|
| 5 |
IC50 = 646.9 nM
|
|
|
|
CP0035175
|
2',15'-dimethyl-5,5'-dioxo-(9'R)-spiro[tetrahydrofuran-2,14'-tetracyclo[8.7.0.02,7.011,15]heptadec-6'-ene]-9-yl ethanethioate
Show/Hide
|
C24H32O4S
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0479805
|
(2S)-N-(3-chloro-4-cyanophenyl)-3-(4-fluoro-2,3-dihydroindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C19H17ClFN3O2
|
1
|
| 1 |
IC50 = 126 nM
|
|
|
|
CP0157502
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluoroindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C20H15F4N3O2
|
1
|
| 1 |
IC50 = 127 nM
|
|
|
|
CP0390357
|
1-[1-benzyl-2,5-dimethyl-4-(4-nitrophenyl)pyrrol-3-yl]ethanone
Show/Hide
|
C21H20N2O3
|
2
|
| 1 |
IC50 = 130 nM
|
|
|
| 2 |
IC50 = 390 nM
|
|
|
|
CP0167968
|
(2S)-N-(3-chloro-4-cyanophenyl)-3-(5-fluoro-2,3-dihydroindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C19H17ClFN3O2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0528413
|
4-[4-oxo-1-(1-oxo-3,4-dihydroisochromen-6-yl)-2-sulfanylidene-1,3-diazaspiro[4.4]nonan-3-yl]-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C24H18F3N3O3S
|
1
|
| 1 |
IC50 = 134.6 nM
|
|
|
|
CP0472860
|
(2S)-3-(4-chloropyrazol-1-yl)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
Show/Hide
|
C15H12ClF3N4O2
|
1
|
| 1 |
IC50 = 136 nM
|
|
|
|
CP0368560
|
(2S)-3-(3-bromo-4-chloropyrazol-1-yl)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
Show/Hide
|
C15H11BrClF3N4O2
|
1
|
| 1 |
IC50 = 138 nM
|
|
|
|
CP0558275
|
4-[4-oxo-1-(1-oxo-3H-2-benzofuran-5-yl)-2-sulfanylidene-9-oxa-1,3-diazaspiro[4.5]decan-3-yl]-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C23H16F3N3O4S
|
1
|
| 1 |
IC50 = 140.9 nM
|
|
|
|
CP0129545
|
(2S)-N-(3-chloro-4-cyanophenyl)-3-(4-fluoroindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C19H15ClFN3O2
|
1
|
| 1 |
IC50 = 142 nM
|
|
|
|
CP0205323
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(2,3-dihydroindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C20H18F3N3O2
|
1
|
| 1 |
IC50 = 142 nM
|
|
|
|
CP0528419
|
4-[4,4-dimethyl-5-oxo-3-(1-oxo-3H-2-benzofuran-5-yl)-2-sulfanylideneimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C21H14F3N3O3S
|
1
|
| 1 |
IC50 = 148.6 nM
|
|
|
|
CP0167962
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(5-fluoro-3-methylindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C21H17F4N3O2
|
1
|
| 1 |
IC50 = 157 nM
|
|
|
|
CP0403482
|
4-[[1-(3-chloro-4-cyanophenyl)-3,5-dimethylpyrazol-4-yl]methyl]-N-(2-hydroxyethyl)benzamide
Show/Hide
|
C22H21ClN4O2
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0258994
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(N-(4-fluorophenyl)anilino)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C24H19F4N3O2
|
1
|
| 1 |
IC50 = 172 nM
|
|
|
|
CP0382455
|
2-chloro-4-[4-(4-fluorophenyl)-3,5-dimethylpyrazol-1-yl]benzonitrile
Show/Hide
|
C18H13ClFN3
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0560913
|
(2S)-3-(3-bromo-4-cyanopyrazol-1-yl)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
Show/Hide
|
C16H11BrF3N5O2
|
1
|
| 1 |
IC50 = 181 nM
|
|
|
|
CP0390359
|
1-benzyl-2,5-dimethyl-4-(4-nitrophenyl)pyrrole-3-carboxylic acid
Show/Hide
|
C20H18N2O4
|
2
|
| 1 |
IC50 = 190 nM
|
|
|
| 2 |
IC50 = 620 nM
|
|
|
|
CP0578673
|
N-(2-aminophenyl)-2-[3-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-1-bicyclo[1.1.1]pentanyl]acetamide
Show/Hide
|
C26H24F3N5O2S
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0552883
|
US10806720, Compound 1020
Show/Hide
|
C15H12F4N4O2
|
1
|
| 1 |
IC50 = 192 nM
|
|
|
|
CP0528420
|
4-[4,4-dimethyl-5-oxo-3-(1-oxo-3,4-dihydroisochromen-6-yl)-2-sulfanylideneimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C22H16F3N3O3S
|
1
|
| 1 |
IC50 = 195.5 nM
|
|
|
|
CP0258993
|
US10806720, Compound 1002
Show/Hide
|
C15H12F4N4O2
|
1
|
| 1 |
IC50 = 199 nM
|
|
|
|
CP0350685
|
(2S)-N-(3-chloro-4-cyanophenyl)-3-(5-fluoro-6-phenylindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C25H19ClFN3O2
|
1
|
| 1 |
IC50 = 203 nM
|
|
|
|
CP0419807
|
US10806720, Compound 1014
Show/Hide
|
C16H12F6N4O2
|
1
|
| 1 |
IC50 = 205 nM
|
|
|
|
CP0528391
|
US10806720, Compound 1043
Show/Hide
|
C15H11F6N5O2
|
1
|
| 1 |
IC50 = 208 nM
|
|
|
|
CP0494926
|
N-[(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(4-methylimidazol-1-yl)-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl]pyridine-4-carboxamide
Show/Hide
|
C29H36N4O
|
3
|
| 1 |
IC50 = 208.8 nM
|
|
|
| 2 |
IC50 = 246.6 nM
|
|
|
| 3 |
IC50 = 268.2 nM
|
|
|
|
CP0244337
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(5-fluoro-6-phenylindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C26H19F4N3O2
|
1
|
| 1 |
IC50 = 215 nM
|
|
|
|
CP0558274
|
4-[8-oxo-5-(1-oxo-3H-2-benzofuran-5-yl)-6-sulfanylidene-5,7-diazaspiro[3.4]octan-7-yl]-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C22H14F3N3O3S
|
1
|
| 1 |
IC50 = 216.7 nM
|
|
|
|
CP0563485
|
US10806720, Compound 1063
Show/Hide
|
C19H14F4N6O2
|
1
|
| 1 |
IC50 = 217 nM
|
|
|
|
CP0396090
|
ethyl 2,5-dimethyl-4-(4-nitrophenyl)-1-phenylpyrrole-3-carboxylate
Show/Hide
|
C21H20N2O4
|
2
|
| 1 |
IC50 = 220 nM
|
|
|
| 2 |
IC50 = 550 nM
|
|
|
|
CP0139066
|
US10806720, Compound 1012
Show/Hide
|
C15H12F4N4O2
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0487849
|
US10806720, Compound 1010
Show/Hide
|
C22H17F4N3O2
|
1
|
| 1 |
IC50 = 226 nM
|
|
|
|
CP0157501
|
(2S)-N-(3-chloro-4-cyanophenyl)-3-(7-fluoroindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C19H15ClFN3O2
|
1
|
| 1 |
IC50 = 234 nM
|
|
|
|
CP0558231
|
4-[4-oxo-1-(1-oxo-3H-2-benzofuran-5-yl)-2-sulfanylidene-7-oxa-1,3-diazaspiro[4.4]nonan-3-yl]-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C22H14F3N3O4S
|
1
|
| 1 |
IC50 = 238.8 nM
|
|
|
|
CP0244332
|
(2S)-N-(3-chloro-4-cyanophenyl)-3-(5-fluoro-6-phenyl-2,3-dihydroindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C25H21ClFN3O2
|
1
|
| 1 |
IC50 = 244 nM
|
|
|
|
CP0551532
|
N-[(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(4-methylimidazol-1-yl)-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl]pyridazine-4-carboxamide
Show/Hide
|
C28H35N5O
|
1
|
| 1 |
IC50 = 244 nM
|
|
|
|
CP0037412
|
(2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorobenzene)sulfonyl]-2-hydroxy-2-methylpropanamide
Show/Hide
|
C18H14F4N2O4S
|
2
|
| 1 |
IC50 = 248 nM
|
|
|
| 2 |
IC50 = 350 nM
|
|
|
|
CP0486844
|
N-[4-cyano-3-(trifluoromethyl)phenyl]-2-(4-fluorophenyl)sulfonylacetamide
Show/Hide
|
C16H10F4N2O3S
|
1
|
| 1 |
IC50 = 248 nM
|
|
|
|
CP0372567
|
3-[[1-(3-chloro-4-cyanophenyl)-3,5-dimethylpyrazol-4-yl]methyl]benzamide
Show/Hide
|
C20H17ClN4O
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0426238
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[4-(4-ethynylphenyl)pyrazol-1-yl]-2-hydroxy-2-methylpropanamide
Show/Hide
|
C23H17F3N4O2
|
1
|
| 1 |
IC50 = 276 nM
|
|
|
|
CP0578493
|
N-(2-aminophenyl)-4-[[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]methyl]benzamide
Show/Hide
|
C27H22F3N5O2S
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0368561
|
US10806720, Compound 1059
Show/Hide
|
C21H15F5N4O2
|
1
|
| 1 |
IC50 = 285 nM
|
|
|
|
CP0040191
|
2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide
Show/Hide
|
C11H11F3N2O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0482005
|
8-fluoro-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4,5-dimethylphenanthridin-6-one
Show/Hide
|
C18H12F7NO2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0398338
|
ethyl 1-(cyclohexylmethyl)-2,5-dimethyl-4-(4-nitrophenyl)pyrrole-3-carboxylate
Show/Hide
|
C22H28N2O4
|
2
|
| 1 |
IC50 = 310 nM
|
|
|
| 2 |
IC50 = 350 nM
|
|
|
|
CP0567779
|
US10806720, Compound 1044
Show/Hide
|
C20H15F4N5O2
|
1
|
| 1 |
IC50 = 317 nM
|
|
|
|
CP0139064
|
(2S)-3-(3-chloro-4-methylpyrazol-1-yl)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
Show/Hide
|
C16H14ClF3N4O2
|
1
|
| 1 |
IC50 = 332 nM
|
|
|
|
CP0403488
|
4-[[1-(3-chloro-4-cyanophenyl)-3,5-dimethylpyrazol-4-yl]methyl]-N-(2-hydroxy-2-methylpropyl)benzamide
Show/Hide
|
C24H25ClN4O2
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0559000
|
US10806720, Compound 1045
Show/Hide
|
C20H15F4N5O2
|
1
|
| 1 |
IC50 = 383 nM
|
|
|
|
CP0576288
|
7-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-N-hydroxyheptanamide
Show/Hide
|
C20H23F3N4O3S
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0577615
|
4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-N-hydroxybutanamide
Show/Hide
|
C17H17F3N4O3S
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0521102
|
4-(4-aminophenyl)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]butanamide
Show/Hide
|
C18H18F3N3O4
|
1
|
| 1 |
IC50 = 392 nM
|
|
|
|
CP0132627
|
US10806720, Compound 1007
Show/Hide
|
C14H12ClFN4O2
|
1
|
| 1 |
IC50 = 427 nM
|
|
|
|
CP0487454
|
US10806720, Compound 1050
Show/Hide
|
C15H12BrF3N4O2
|
1
|
| 1 |
IC50 = 427 nM
|
|
|
|
CP0426241
|
US10806720, Compound 1024
Show/Hide
|
C15H12F4N4O
|
1
|
| 1 |
IC50 = 462 nM
|
|
|
|
CP0396091
|
1-[[6-chloro-5-(hydroxymethyl)pyridin-3-yl]methyl]-4-(4-cyanophenyl)-5-methylpyrrole-3-carbonitrile
Show/Hide
|
C20H15ClN4O
|
2
|
| 1 |
IC50 = 490 nM
|
|
|
| 2 |
IC50 = 1100 nM
|
|
|
|
CP0400676
|
2-chloro-4-[3,5-dimethyl-4-[[4-(morpholine-4-carbonyl)phenyl]methyl]pyrazol-1-yl]benzonitrile
Show/Hide
|
C24H23ClN4O2
|
1
|
| 1 |
IC50 = 510 nM
|
|
|
|
CP0494925
|
N-[(3S,8R,9S,10R,13S,14S)-17-imidazol-1-yl-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl]pyridine-4-carboxamide
Show/Hide
|
C28H34N4O
|
1
|
| 1 |
IC50 = 511.2 nM
|
|
|
|
CP0556814
|
5-[4-oxo-1-(1-oxo-3H-2-benzofuran-5-yl)-2-sulfanylidene-7-oxa-1,3-diazaspiro[4.4]nonan-3-yl]-3-(trifluoromethyl)pyridine-2-carbonitrile
Show/Hide
|
C21H13F3N4O4S
|
1
|
| 1 |
IC50 = 516.2 nM
|
|
|
|
CP0542611
|
(2S)-3-(3-cyano-4-phenylpyrazol-1-yl)-N-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-2-hydroxy-2-methylpropanamide
Show/Hide
|
C21H15F3N6O2
|
1
|
| 1 |
IC50 = 579 nM
|
|
|
|
CP0553184
|
4-[4,4-dimethyl-3-(2-methyl-1-oxo-3H-isoindol-5-yl)-5-oxo-2-sulfanylideneimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C22H17F3N4O2S
|
1
|
| 1 |
IC50 = 590.2 nM
|
|
|
|
CP0440038
|
(2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(5-fluoroindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C20H15F4N3O2
|
1
|
| 1 |
IC50 = 598 nM
|
|
|
|
CP0577993
|
4-[7-oxo-4-(1-oxo-3H-2-benzofuran-5-yl)-5-sulfanylidene-4,6-diazaspiro[2.4]heptan-6-yl]-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C21H12F3N3O3S
|
1
|
| 1 |
IC50 = 669.6 nM
|
|
|
|
CP0167960
|
(2S)-3-(5-cyanopyrrolo[3,2-b]pyridin-1-yl)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
Show/Hide
|
C20H14F3N5O2
|
1
|
| 1 |
IC50 = 686 nM
|
|
|
|
CP0577061
|
N-(2-aminophenyl)-5-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C25H19F3N6O2S
|
1
|
| 1 |
IC50 = 750 nM
|
|
|
|
CP0317479
|
US10806720, Compound 1035
Show/Hide
|
C17H15F3N4O3
|
1
|
| 1 |
IC50 = 758 nM
|
|
|
|
CP0498412
|
methyl N-[4-[1-[(2S)-3-[4-cyano-3-(trifluoromethyl)anilino]-2-hydroxy-2-methyl-3-oxopropyl]pyrazol-4-yl]phenyl]carbamate
Show/Hide
|
C23H20F3N5O4
|
1
|
| 1 |
IC50 = 827 nM
|
|
|
|
CP0337614
|
(2S)-3-(5-bromo-2,3-dihydroindol-1-yl)-N-(3-chloro-4-cyanophenyl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C19H17BrClN3O2
|
1
|
| 1 |
IC50 = 835 nM
|
|
|
|
CP0440037
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[4-fluoro-6-(4-fluorophenyl)indol-1-yl]-2-hydroxy-2-methylpropanamide
Show/Hide
|
C26H18F5N3O2
|
1
|
| 1 |
IC50 = 898 nM
|
|
|
|
CP0560914
|
US10806720, Compound 1032
Show/Hide
|
C17H15ClF3N5O3
|
1
|
| 1 |
IC50 = 901 nM
|
|
|
|
CP0488233
|
N-[(3S,8R,9S,10R,13S,14S)-17-(5-methoxypyridin-3-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl]pyridazine-4-carboxamide
Show/Hide
|
C30H36N4O2
|
1
|
| 1 |
IC50 = 914.5 nM
|
|
|
|
CP0244336
|
(2S)-3-(5-bromoindol-1-yl)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
Show/Hide
|
C20H15BrF3N3O2
|
1
|
| 1 |
IC50 = 918 nM
|
|
|
|
CP0372563
|
4-[[1-(3-chloro-4-cyanophenyl)-3,5-dimethylpyrazol-4-yl]methyl]-N,N-dimethylbenzamide
Show/Hide
|
C22H21ClN4O
|
1
|
| 1 |
IC50 = 920 nM
|
|
|
|
CP0553185
|
5-[4,4-dimethyl-5-oxo-3-(1-oxo-3H-2-benzofuran-5-yl)-2-sulfanylideneimidazolidin-1-yl]-3-(trifluoromethyl)pyridine-2-carbonitrile
Show/Hide
|
C20H13F3N4O3S
|
1
|
| 1 |
IC50 = 941.1 nM
|
|
|
|
CP0479964
|
US10806720, Compound 1025
Show/Hide
|
C21H16F4N4O2
|
1
|
| 1 |
IC50 = 969 nM
|
|
|
|
CP0244335
|
ethyl 1-[(2S)-3-[4-cyano-3-(trifluoromethyl)anilino]-2-hydroxy-2-methyl-3-oxopropyl]indole-3-carboxylate
Show/Hide
|
C23H20F3N3O4
|
1
|
| 1 |
IC50 = 972 nM
|
|
|
|
CP0543626
|
N-(2-aminophenyl)-4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]benzamide
Show/Hide
|
C26H20F3N5O2S
|
1
|
| 1 |
IC50 = 980 nM
|
|
|
|
CP0568640
|
N-[(3S,8R,9S,10R,13S,14S)-17-imidazol-1-yl-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl]pyridazine-4-carboxamide
Show/Hide
|
C27H33N5O
|
1
|
| 1 |
IC50 = 980.8 nM
|
|
|
|
CP0556821
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-3-(5-iodoindol-1-yl)-2-methylpropanamide
Show/Hide
|
C20H15F3IN3O2
|
1
|
| 1 |
IC50 = 985 nM
|
|
|
|
CP0569453
|
US10806720, Compound 1019
Show/Hide
|
C15H11F6N5O2
|
1
|
| 1 |
IC50 = 1013 nM
|
|
|
|
CP0440036
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluoro-5-phenylindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C26H19F4N3O2
|
1
|
| 1 |
IC50 = 1015 nM
|
|
|
|
CP0568420
|
US10806720, Compound 1016
Show/Hide
|
C16H18F3N3O3
|
1
|
| 1 |
IC50 = 1018 nM
|
|
|
|
CP0569452
|
US10806720, Compound 1005
Show/Hide
|
C15H12BrF3N4O2
|
1
|
| 1 |
IC50 = 1019 nM
|
|
|
|
CP0473258
|
(2S)-N-(3-chloro-4-cyanophenyl)-3-(5-fluoro-3-phenylindol-1-yl)-2-hydroxy-2-methylpropanamide
Show/Hide
|
C25H19ClFN3O2
|
1
|
| 1 |
IC50 = 1032 nM
|
|
|
|
CP0552055
|
US10806720, Compound 1015
Show/Hide
|
C21H16F4N4O2
|
1
|
| 1 |
IC50 = 1069 nM
|
|
|
|
CP0487875
|
US10806720, Compound 1018
Show/Hide
|
C14H12F3N5O2
|
1
|
| 1 |
IC50 = 1091 nM
|
|
|
|
CP0400677
|
4-[1-(3-chloro-4-cyanophenyl)-3,5-dimethylpyrazol-4-yl]oxy-N-(2-hydroxy-2-methylpropyl)benzamide
Show/Hide
|
C23H23ClN4O3
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0189556
|
GALETERONE
Show/Hide
|
C26H32N2O
|
1
|
| 1 |
IC50 = 1108 nM
|
|
|
|
CP0498410
|
4-[(5S)-5-[(4-fluoropyrazol-1-yl)methyl]-5-methyl-2,4-dioxo-1,3-oxazolidin-3-yl]-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C16H10F4N4O3
|
1
|
| 1 |
IC50 = 1131 nM
|
|
|
|
CP0552056
|
US10806720, Compound 1003
Show/Hide
|
C21H17F3N4O2
|
1
|
| 1 |
IC50 = 1152 nM
|
|
|
|
CP0244662
|
tert-butyl N-[4-[1-[(2S)-3-[4-cyano-3-(trifluoromethyl)anilino]-2-hydroxy-2-methyl-3-oxopropyl]pyrazol-4-yl]phenyl]carbamate
Show/Hide
|
C26H26F3N5O4
|
1
|
| 1 |
IC50 = 1153 nM
|
|
|
|
CP0564518
|
5-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-N-hydroxypentanamide
Show/Hide
|
C18H19F3N4O3S
|
1
|
| 1 |
IC50 = 1170 nM
|
|
|
|
CP0372566
|
N-[5-[1-(3-chloro-4-cyanophenyl)-3,5-dimethylpyrazol-4-yl]oxypyridin-2-yl]acetamide
Show/Hide
|
C19H16ClN5O2
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0551531
|
N-[(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(4-methylimidazol-1-yl)-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl]pyridine-3-carboxamide
Show/Hide
|
C29H36N4O
|
1
|
| 1 |
IC50 = 1285 nM
|
|
|
|
CP0382457
|
2-chloro-4-[3,5-dimethyl-4-[4-(morpholine-4-carbonyl)phenoxy]pyrazol-1-yl]benzonitrile
Show/Hide
|
C23H21ClN4O3
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0543013
|
N-[(3S,8R,9S,10R,13S,14S)-17-(benzimidazol-1-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl]pyridazine-4-carboxamide
Show/Hide
|
C31H35N5O
|
1
|
| 1 |
IC50 = 1348 nM
|
|
|
|
CP0317480
|
US10806720, Compound 1013
Show/Hide
|
C15H13F3N4O2
|
1
|
| 1 |
IC50 = 1442 nM
|
|
|
|
CP0571627
|
6-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-N-hydroxyhexanamide
Show/Hide
|
C19H21F3N4O3S
|
1
|
| 1 |
IC50 = 1450 nM
|
|
|
|
CP0382458
|
3-chloro-4-[4-[(4-fluorophenyl)methyl]-3,5-dimethylpyrazol-1-yl]benzonitrile
Show/Hide
|
C19H15ClFN3
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0542740
|
N-[(3S,8R,9S,10R,13S,14S)-17-(benzimidazol-1-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl]pyridine-4-carboxamide
Show/Hide
|
C32H36N4O
|
1
|
| 1 |
IC50 = 1551 nM
|
|
|
|
CP0533682
|
N-[(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(5-methylpyridin-3-yl)-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl]pyridazine-4-carboxamide
Show/Hide
|
C30H36N4O
|
1
|
| 1 |
IC50 = 1641 nM
|
|
|
|
CP0174028
|
N-(2-aminophenyl)-4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluorobenzamide
Show/Hide
|
C26H19F4N5O2S
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0394584
|
8-fluoro-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4-methyl-5H-phenanthridin-6-one
Show/Hide
|
C17H10F7NO2
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0568422
|
US10806720, Compound 1008
Show/Hide
|
C14H13ClN4O2
|
1
|
| 1 |
IC50 = 1856 nM
|
|
|
|
CP0479965
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-3-(4-iodopyrazol-1-yl)-2-methylpropanamide
Show/Hide
|
C15H12F3IN4O2
|
1
|
| 1 |
IC50 = 2038 nM
|
|
|
|
CP0280646
|
US10806720, Compound 1029
Show/Hide
|
C14H10F4N4O
|
1
|
| 1 |
IC50 = 2124 nM
|
|
|
|
CP0577992
|
4-[3-oxo-1-sulfanylidene-7-[6-(trifluoromethyl)pyridin-3-yl]-4,5-dihydro-3aH-imidazo[1,5-a]quinolin-2-yl]-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C25H14F6N4OS
|
1
|
| 1 |
IC50 = 2183 nM
|
|
|
|
CP0553186
|
5-[4-oxo-1-(7-oxo-5H-furo[3,4-b]pyridin-3-yl)-2-sulfanylidene-1,3-diazaspiro[4.4]nonan-3-yl]-3-(trifluoromethyl)pyridine-2-carbonitrile
Show/Hide
|
C21H14F3N5O3S
|
1
|
| 1 |
IC50 = 2219 nM
|
|
|
|
CP0578295
|
4-[4,4-dimethyl-5-oxo-3-(7-oxo-5H-furo[3,4-b]pyridin-3-yl)-2-sulfanylideneimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C20H13F3N4O3S
|
1
|
| 1 |
IC50 = 2292 nM
|
|
|
|
CP0571628
|
N-(2-aminophenyl)-6-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]pyridine-3-carboxamide
Show/Hide
|
C25H19F3N6O2S
|
1
|
| 1 |
IC50 = 2340 nM
|
|
|
|
CP0552884
|
US10806720, Compound 1041
Show/Hide
|
C12H12ClFN4O2
|
1
|
| 1 |
IC50 = 2470 nM
|
|
|
|
CP0577991
|
4-(3-oxo-1-sulfanylidene-4,5-dihydro-3aH-imidazo[1,5-a]quinolin-2-yl)-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C19H12F3N3OS
|
1
|
| 1 |
IC50 = 2837 nM
|
|
|
|
CP0553182
|
4-(3-oxo-7-phenyl-1-sulfanylidene-4,5-dihydro-3aH-imidazo[1,5-a]quinolin-2-yl)-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C25H16F3N3OS
|
1
|
| 1 |
IC50 = 3438 nM
|
|
|
|
CP0428029
|
6-[1-butyl-5-(4-fluorophenyl)-3-methylpyrazol-4-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C22H22FN3O2
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0379928
|
6-[5-(4-fluorophenyl)-3-methyl-1-(2-methylpropyl)pyrazol-4-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C22H22FN3O2
|
1
|
| 1 |
IC50 = 3700 nM
|
|
|
|
CP0560312
|
4-(3-oxo-7-pyridin-3-yl-1-sulfanylidene-4,5-dihydro-3aH-imidazo[1,5-a]quinolin-2-yl)-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C24H15F3N4OS
|
1
|
| 1 |
IC50 = 3906 nM
|
|
|
|
CP0418099
|
1-[4-[[4-[(2R)-2,3-dihydroxypropoxy]-3-methylphenyl]-diethylsilyl]-2-methylphenoxy]-3,3-dimethylbutan-2-one
Show/Hide
|
C27H40O5Si
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0400267
|
2-[[1-(3-chloro-4-cyanophenyl)-3,5-dimethylpyrazol-4-yl]methyl]benzamide
Show/Hide
|
C20H17ClN4O
|
1
|
| 1 |
IC50 = 4200 nM
|
|
|
|
CP0397140
|
N-[6-[1-(3-chloro-4-cyanophenyl)-3,5-dimethylpyrazol-4-yl]oxypyridin-3-yl]-2,2-dimethylpropanamide
Show/Hide
|
C22H22ClN5O2
|
1
|
| 1 |
IC50 = 4300 nM
|
|
|
|
CP0558228
|
4-(7-bromo-3-oxo-1-sulfanylidene-4,5-dihydro-3aH-imidazo[1,5-a]quinolin-2-yl)-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C19H11BrF3N3OS
|
1
|
| 1 |
IC50 = 4377 nM
|
|
|
|
CP0578294
|
4-[7-(1-cyclopropylpyrazol-3-yl)-3-oxo-1-sulfanylidene-4,5-dihydro-3aH-imidazo[1,5-a]quinolin-2-yl]-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C25H18F3N5OS
|
1
|
| 1 |
IC50 = 4527 nM
|
|
|
|
CP0280648
|
US10806720, Compound 1011
Show/Hide
|
C21H17F3N4O2
|
1
|
| 1 |
IC50 = 4770 nM
|
|
|
|
CP0385142
|
N-(4-phenoxyphenyl)-3-(trifluoromethyl)benzenesulfonamide
Show/Hide
|
C19H14F3NO3S
|
1
|
| 1 |
IC50 = 5300 nM
|
|
|
|
CP0403484
|
N-[6-[1-(3-chloro-4-cyanophenyl)-3,5-dimethylpyrazol-4-yl]oxypyridin-3-yl]acetamide
Show/Hide
|
C19H16ClN5O2
|
1
|
| 1 |
IC50 = 5400 nM
|
|
|
|
CP0426242
|
US10806720, Compound 1052
Show/Hide
|
C15H11F4IN4O2
|
1
|
| 1 |
IC50 = 5450 nM
|
|
|
|
CP0496388
|
(2S)-3-(3-bromo-4-cyanopyrazol-1-yl)-N-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-2-hydroxy-2-methylpropanamide
Show/Hide
|
C15H10BrF3N6O2
|
1
|
| 1 |
IC50 = 5481 nM
|
|
|
|
CP0428028
|
6-[1-benzyl-5-(4-fluorophenyl)-3-methylpyrazol-4-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C25H20FN3O2
|
1
|
| 1 |
IC50 = 5600 nM
|
|
|
|
CP0540771
|
(2S)-3-[4-[diethyl-[4-[(2R)-2-hydroxy-3,3-dimethylbutoxy]-3-methylphenyl]silyl]-2-methylphenoxy]propane-1,2-diol
Show/Hide
|
C27H42O5Si
|
1
|
| 1 |
IC50 = 5800 nM
|
|
|
|
CP0558230
|
4-[7-(3,5-dimethyl-1,2-oxazol-4-yl)-3-oxo-1-sulfanylidene-4,5-dihydro-3aH-imidazo[1,5-a]quinolin-2-yl]-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C24H17F3N4O2S
|
1
|
| 1 |
IC50 = 5978 nM
|
|
|
|
CP0426243
|
US10806720, Compound 1030
Show/Hide
|
C19H21F3N6O4
|
1
|
| 1 |
IC50 = 6108 nM
|
|
|
|
CP0484209
|
1-[4-[[4-(3,3-dimethyl-2-oxobutoxy)-3-methylphenyl]-diethylsilyl]-2-methylphenoxy]-3,3-dimethylbutan-2-one
Show/Hide
|
C30H44O4Si
|
1
|
| 1 |
IC50 = 6200 nM
|
|
|
|
CP0506983
|
(2R)-3-[4-[diethyl-[4-[(2R)-2-hydroxy-3,3-dimethylbutoxy]-3-methylphenyl]silyl]-2-methylphenoxy]propane-1,2-diol
Show/Hide
|
C27H42O5Si
|
1
|
| 1 |
IC50 = 6700 nM
|
|
|
|
CP0895019
|
3-(4-(Diethyl(4-(2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)silyl)-2-methylphenoxy)propane-1,2-diol
Show/Hide
|
C27H42O5Si
|
1
|
| 1 |
IC50 = 6800 nM
|
|
|
|
CP0392397
|
(2R)-3-[4-[diethyl-[4-[(2S)-2-hydroxy-3,3-dimethylbutoxy]-3-methylphenyl]silyl]-2-methylphenoxy]propane-1,2-diol
Show/Hide
|
C27H42O5Si
|
1
|
| 1 |
IC50 = 7400 nM
|
|
|
|
CP0552833
|
4-[7-(2-chloropyrimidin-5-yl)-3-oxo-1-sulfanylidene-4,5-dihydro-3aH-imidazo[1,5-a]quinolin-2-yl]-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C23H13ClF3N5OS
|
1
|
| 1 |
IC50 = 8075 nM
|
|
|
|
CP0552119
|
US10806720, Compound 1055
Show/Hide
|
C16H15F3N4O2
|
1
|
| 1 |
IC50 = 8087 nM
|
|
|
|
CP0506982
|
(2S)-3-[4-[diethyl-[4-[(2S)-2-hydroxy-3,3-dimethylbutoxy]-3-methylphenyl]silyl]-2-methylphenoxy]propane-1,2-diol
Show/Hide
|
C27H42O5Si
|
1
|
| 1 |
IC50 = 8300 nM
|
|
|
|
CP0553183
|
4-(3-oxo-7-quinolin-3-yl-1-sulfanylidene-4,5-dihydro-3aH-imidazo[1,5-a]quinolin-2-yl)-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C28H17F3N4OS
|
1
|
| 1 |
IC50 = 8953 nM
|
|
|
|
CP0353077
|
N-[(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(triazol-1-yl)-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl]pyridazine-4-carboxamide
Show/Hide
|
C26H32N6O
|
1
|
| 1 |
IC50 = 9145 nM
|
|
|
|
CP0428030
|
6-[1-(3,3-difluorobutyl)-5-(4-fluorophenyl)-3-methylpyrazol-4-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C22H20F3N3O2
|
1
|
| 1 |
IC50 = 9200 nM
|
|
|
|
CP0556813
|
4-(7-bromo-3-oxo-1-sulfanylidene-4,5-dihydro-3aH-imidazo[1,5-a]quinoxalin-2-yl)-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C18H10BrF3N4OS
|
1
|
| 1 |
IC50 = 9862 nM
|
|
|
|
CP0003145
|
(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
Show/Hide
|
C27H44O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0134848
|
LG-190178
Show/Hide
|
C28H42O5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0216245
|
LG190155
Show/Hide
|
C31H44O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0368663
|
1-[4-[diethyl-[3-methyl-4-(oxiran-2-ylmethoxy)phenyl]silyl]-2-methylphenoxy]-3,3-dimethylbutan-2-one
Show/Hide
|
C27H38O4Si
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0392396
|
LG190176
Show/Hide
|
C28H38O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0433395
|
1-[4-[[4-[(2S)-2,3-dihydroxypropoxy]-3-methylphenyl]-diethylsilyl]-2-methylphenoxy]-3,3-dimethylbutan-2-one
Show/Hide
|
C27H40O5Si
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0450261
|
1-[4-[[4-[[(2R)-2,3-dihydroxypropyl]amino]-3-methylphenyl]-diethylsilyl]-2-methylphenoxy]-3,3-dimethylbutan-2-one
Show/Hide
|
C27H41NO4Si
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0500703
|
1-[4-[[4-[[(2S)-2,3-dihydroxypropyl]amino]-3-methylphenyl]-diethylsilyl]-2-methylphenoxy]-3,3-dimethylbutan-2-one
Show/Hide
|
C27H41NO4Si
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0500704
|
4-[diethyl-[4-[(2R)-2-hydroxy-3,3-dimethylbutoxy]-3-methylphenyl]silyl]-2-methylphenol
Show/Hide
|
C24H36O3Si
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0386197
|
6-[4-(4-fluorophenyl)-2-methyl-5-oxo-2H-furan-3-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C19H14FNO4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0386198
|
6-[1-ethyl-4-(4-fluorophenyl)-2-methyl-5-oxo-2H-pyrrol-3-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C21H19FN2O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0386199
|
6-[4-(4-fluorophenyl)-5-oxo-2H-furan-3-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C18H12FNO4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0397446
|
6-[4-(4-fluorophenyl)-2-methyl-5-oxo-1,2-dihydropyrrol-3-yl]-8-methyl-4H-1,4-benzoxazin-3-one
Show/Hide
|
C20H17FN2O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0397447
|
6-[4-(4-fluoro-2-methylphenyl)-5-oxo-2H-furan-3-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C19H14FNO4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0403919
|
8-chloro-6-[4-(4-fluorophenyl)-2-methyl-5-oxo-1,2-dihydropyrrol-3-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C19H14ClFN2O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0403920
|
6-[4-(4-fluorophenyl)-2,2-dimethyl-5-oxofuran-3-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C20H16FNO4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0403922
|
6-[4-(4-fluorophenyl)-1-(2-hydroxyethyl)-2-methyl-5-oxo-2H-pyrrol-3-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C21H19FN2O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0403923
|
6-[4-(2,4-difluorophenyl)-5-oxo-2H-furan-3-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C18H11F2NO4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0484531
|
6-[2-ethyl-4-(4-fluorophenyl)-5-oxo-2H-furan-3-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C20H16FNO4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0484532
|
8-fluoro-6-[4-(4-fluorophenyl)-2-methyl-5-oxo-1,2-dihydropyrrol-3-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C19H14F2N2O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0484690
|
6-[2-fluoro-4-(4-fluorophenyl)-2-methyl-5-oxofuran-3-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C19H13F2NO4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0489371
|
6-[1-cyclopropyl-4-(4-fluorophenyl)-2-methyl-5-oxo-2H-pyrrol-3-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C22H19FN2O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0489372
|
6-[4-(4-fluorophenyl)-1,2-dimethyl-5-oxo-2H-pyrrol-3-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C20H17FN2O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0489373
|
6-[4-(4-fluorophenyl)-2-methyl-5-oxo-1,2-dihydropyrrol-3-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C19H15FN2O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0100868
|
methyl (1R,2S,9R,10R,11S,14R,15S,17R)-2,15-dimethyl-5,5'-dioxospiro[18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadec-6-ene-14,2'-oxolane]-9-carboxylate
Show/Hide
|
C24H30O6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0236141
|
6-[2-(4-fluoro-2-methylphenyl)-5-(trifluoromethyl)pyrazol-3-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C19H13F4N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0379342
|
6-[5-(4-fluorophenyl)-1,3-dimethylpyrazol-4-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C19H16FN3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0379885
|
6-[1-(2,2-difluoro-4-hydroxybutyl)-5-(4-fluorophenyl)-3-methylpyrazol-4-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C22H20F3N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0379889
|
6-[4-(4-fluorophenyl)-5-methyl-1,2-oxazol-3-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C18H13FN2O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0379930
|
6-[5-(4-fluorophenyl)-1,3-dimethylpyrazol-4-yl]-8-methyl-4H-1,4-benzoxazin-3-one
Show/Hide
|
C20H18FN3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0418723
|
6-[5-(4-fluorophenyl)-3-methyl-1-(pyridin-4-ylmethyl)pyrazol-4-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H19FN4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0418725
|
6-[5-(4-fluorophenyl)-1-(4-hydroxybutyl)-3-methylpyrazol-4-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C22H22FN3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0418726
|
6-[5-(4-fluorophenyl)-3-methyl-1-(4,4,4-trifluorobutyl)pyrazol-4-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C22H19F4N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0418729
|
N-[2-[5-(4-fluorophenyl)-3-methyl-4-(3-oxo-4H-1,4-benzoxazin-6-yl)pyrazol-1-yl]ethyl]methanesulfonamide
Show/Hide
|
C21H21FN4O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0418792
|
6-[1-(2,2-difluoro-3-hydroxypropyl)-5-(4-fluorophenyl)-3-methylpyrazol-4-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C21H18F3N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0418804
|
6-[5-(4-fluorophenyl)-3-methyl-1-propylpyrazol-4-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C21H20FN3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0418805
|
6-[5-(4-fluorophenyl)-3-methyl-1-(pyridin-3-ylmethyl)pyrazol-4-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H19FN4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0418954
|
6-[4-(4-fluorophenyl)-5-methyl-1H-pyrazol-3-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C18H14FN3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0418955
|
6-[5-(4-fluorophenyl)-3-methyl-1-(pyridin-2-ylmethyl)pyrazol-4-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H19FN4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0418959
|
6-[5-(4-fluorophenyl)-1-(3-hydroxypropyl)-3-methylpyrazol-4-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C21H20FN3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0428025
|
6-[1-(3,3-difluoro-4-hydroxybutyl)-5-(4-fluorophenyl)-3-methylpyrazol-4-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C22H20F3N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0428026
|
6-[5-(4-fluorophenyl)-1-methylpyrazol-4-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C18H14FN3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0428027
|
6-[5-(2,4-difluorophenyl)-1,3-dimethylpyrazol-4-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C19H15F2N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0459594
|
6-[1-ethyl-5-(4-fluorophenyl)-3-methylpyrazol-4-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C20H18FN3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0498692
|
3-[5-(4-fluorophenyl)-3-methyl-4-(3-oxo-4H-1,4-benzoxazin-6-yl)pyrazol-1-yl]propanenitrile
Show/Hide
|
C21H17FN4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0167961
|
1-[(2S)-3-[4-cyano-3-(trifluoromethyl)anilino]-2-hydroxy-2-methyl-3-oxopropyl]indole-3-carboxylic acid
Show/Hide
|
C21H16F3N3O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0440039
|
2-hydroxy-4-(4-isothiocyanatophenyl)-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]butanamide
Show/Hide
|
C19H16F3N3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0531158
|
(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-3-(4-phenylindol-1-yl)propanamide
Show/Hide
|
C26H20F3N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0004988
|
pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate
Show/Hide
|
C21H20N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0552027
|
N-(2-amino-5-thiophen-2-ylphenyl)-6-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]pyridine-3-carboxamide
Show/Hide
|
C29H21F3N6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0577252
|
N-(2-amino-5-phenylphenyl)-6-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]pyridine-3-carboxamide
Show/Hide
|
C31H23F3N6O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0577253
|
N-(2-amino-5-phenylphenyl)-5-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C31H23F3N6O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0578419
|
N-(2-amino-5-thiophen-2-ylphenyl)-5-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C29H21F3N6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0579748
|
N-(2-amino-5-phenylphenyl)-4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]benzamide
Show/Hide
|
C32H24F3N5O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0560311
|
4-(7-bromo-3-oxo-1-sulfanylidene-3a,4-dihydroimidazo[5,1-c][1,4]benzothiazin-2-yl)-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C18H9BrF3N3OS2
|
1
|
| 1 |
IC50 = 18140 nM
|
|
|
|
CP0394583
|
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4-methyl-5H-phenanthridin-6-one
Show/Hide
|
C17H11F6NO2
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0552834
|
5-[8-oxo-5-(1-oxo-3H-2-benzofuran-5-yl)-6-sulfanylidene-2-oxa-5,7-diazaspiro[3.4]octan-7-yl]-3-(trifluoromethyl)pyridine-2-carbonitrile
Show/Hide
|
C20H11F3N4O4S
|
1
|
| 1 |
IC50 = 26735 nM
|
|
|
|
CP0558229
|
4-[3-oxo-1-sulfanylidene-7-[4-(trifluoromethyl)phenyl]-4,5-dihydro-3aH-imidazo[1,5-a]quinolin-2-yl]-2-(trifluoromethyl)benzonitrile
Show/Hide
|
C26H15F6N3OS
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0035186
|
(10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]-14-hydroxy-15-methyl-14-(prop-1-yn-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1,6-dien-5-one
Show/Hide
|
C29H35NO2
|
1
|
| 1 |
Ki = 5.95 nM
|
|
|
|
CP0421494
|
N-[3-[(1E)-1-(6H-benzo[c][1]benzoxepin-11-ylidene)ethyl]phenyl]methanesulfonamide
Show/Hide
|
C23H21NO3S
|
1
|
| 1 |
Ki = 5.98 nM
|
|
|
|
CP0421495
|
N-[3-[(1E)-1-(6H-benzo[c][1]benzoxepin-11-ylidene)propyl]phenyl]methanesulfonamide
Show/Hide
|
C24H23NO3S
|
1
|
| 1 |
Ki = 9.74 nM
|
|
|
|
CP0438181
|
3-[(4-methoxyphenyl)phenylmethyl]indole
Show/Hide
|
C22H19NO
|
1
|
| 1 |
Ki = 68.9 nM
|
|
|
|
CP0413728
|
N-[3-(3-chlorophenyl)-1H-indol-7-yl]methanesulfonamide
Show/Hide
|
C15H13ClN2O2S
|
1
|
| 1 |
Ki = 91 nM
|
|
|
|
CP0035170
|
(S)-N-(3-(1-cyclopropyl-1-(2,4-difluorophenyl)ethyl)-1H-indol-7-yl)methanesulfonamide
Show/Hide
|
C20H20F2N2O2S
|
1
|
| 1 |
Ki = 211 nM
|
|
|
|
CP0862736
|
N-(3-(1-cyclopropyl-1-(4-fluorophenyl)ethyl)-1H-indol-7-yl)methanesulfonamide
Show/Hide
|
C20H21FN2O2S
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0410986
|
N-[2-[[benzyl(methyl)amino]methyl]-5-tert-butyl-3-(4-fluoro-2-methoxyphenyl)-1H-indol-7-yl]methanesulfonamide
Show/Hide
|
C29H34FN3O3S
|
1
|
| 1 |
Ki = 231 nM
|
|
|
|
CP0444548
|
N-[2-[[benzyl(methyl)amino]methyl]-3-(4-fluoro-2-methoxyphenyl)-5-propan-2-yl-1H-indol-7-yl]methanesulfonamide
Show/Hide
|
C28H32FN3O3S
|
1
|
| 1 |
Ki = 232 nM
|
|
|
|
CP0395284
|
N-[3-[(1Z)-1-(10-methoxy-6H-benzo[c][1]benzoxepin-11-ylidene)propyl]phenyl]methanesulfonamide
Show/Hide
|
C25H25NO4S
|
1
|
| 1 |
Ki = 239 nM
|
|
|
|
CP0383683
|
N-(1H-indol-7-yl)methanesulfonamide
Show/Hide
|
C9H10N2O2S
|
1
|
| 1 |
Ki = 355 nM
|
|
|
|
CP0513116
|
N-[3-(2-methoxyphenyl)-1H-indol-7-yl]methanesulfonamide
Show/Hide
|
C16H16N2O3S
|
1
|
| 1 |
Ki = 401 nM
|
|
|
|
CP0473189
|
N-[3-(4-cyano-3-methylphenyl)-1-propan-2-ylindol-6-yl]methanesulfonamide
Show/Hide
|
C20H21N3O2S
|
1
|
| 1 |
Ki = 403 nM
|
|
|
|
CP0395286
|
N-[3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidenemethyl)phenyl]methanesulfonamide
Show/Hide
|
C23H21NO2S
|
1
|
| 1 |
Ki = 418 nM
|
|
|
|
CP0398882
|
N-[3-(4-cyano-3-methoxyphenyl)-1-propan-2-ylindol-6-yl]methanesulfonamide
Show/Hide
|
C20H21N3O3S
|
1
|
| 1 |
Ki = 490 nM
|
|
|
|
CP0412669
|
N-[3-(4-fluorophenyl)-1H-indol-7-yl]methanesulfonamide
Show/Hide
|
C15H13FN2O2S
|
1
|
| 1 |
Ki = 496 nM
|
|
|
|
CP0505641
|
N-[3-(4-cyano-3-fluorophenyl)-1-propan-2-ylindol-6-yl]methanesulfonamide
Show/Hide
|
C19H18FN3O2S
|
1
|
| 1 |
Ki = 648 nM
|
|
|
|
CP0035174
|
(R)-N-(3-(1-cyclopropyl-1-(2,4-difluorophenyl)ethyl)-1H-indol-7-yl)methanesulfonamide
Show/Hide
|
C20H20F2N2O2S
|
1
|
| 1 |
Ki = 676 nM
|
|
|
|
CP0429171
|
N-[2-benzyl-3-(4-fluoro-2-methoxyphenyl)-5-propan-2-yl-1H-indol-7-yl]methanesulfonamide
Show/Hide
|
C26H27FN2O3S
|
1
|
| 1 |
Ki = 684 nM
|
|
|
|
CP0416932
|
N-[3-(5-chloro-2-methoxyphenyl)-1H-indol-7-yl]methanesulfonamide
Show/Hide
|
C16H15ClN2O3S
|
1
|
| 1 |
Ki = 697 nM
|
|
|
|
CP0444573
|
N-[3-(5-fluoro-2-methoxyphenyl)-2-phenyl-1H-indol-7-yl]methanesulfonamide
Show/Hide
|
C22H19FN2O3S
|
1
|
| 1 |
Ki = 905 nM
|
|
|
|
CP0468484
|
N-[3-(5-fluoro-2-methoxyphenyl)-5-methoxy-2-methyl-1H-indol-7-yl]methanesulfonamide
Show/Hide
|
C18H19FN2O4S
|
1
|
| 1 |
Ki = 1120 nM
|
|
|
|
CP0413727
|
N-[5-fluoro-3-(4-fluoro-2-methoxyphenyl)-2-methyl-1H-indol-7-yl]methanesulfonamide
Show/Hide
|
C17H16F2N2O3S
|
1
|
| 1 |
Ki = 1130 nM
|
|
|
|
CP0008077
|
(1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
Show/Hide
|
C22H29FO5
|
1
|
| 1 |
Ki = 1410 nM
|
|
|
|
CP0473330
|
(S)-N-(1-sec-butyl-3-(4-cyanophenyl)-1H-indol-6-yl)methanesulfonamide
Show/Hide
|
C20H21N3O2S
|
1
|
| 1 |
Ki = 1740 nM
|
|
|
|
CP0047174
|
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
Show/Hide
|
C21H28O5
|
1
|
| 1 |
Ki = 2520 nM
|
|
|
|
CP0398867
|
(R)-N-(1-sec-butyl-3-(4-cyanophenyl)-1H-indol-6-yl)methanesulfonamide
Show/Hide
|
C20H21N3O2S
|
1
|
| 1 |
Ki = 2550 nM
|
|
|
|
CP0408933
|
N-[3-(4-cyanophenyl)-1-ethylindol-6-yl]methanesulfonamide
Show/Hide
|
C18H17N3O2S
|
1
|
| 1 |
Ki = 2590 nM
|
|
|
|
CP0429188
|
N-(5-methoxy-2-methyl-3-phenyl-1H-indol-7-yl)methanesulfonamide
Show/Hide
|
C17H18N2O3S
|
1
|
| 1 |
Ki = 4060 nM
|
|
|
|
CP0450605
|
2-[[benzyl(methyl)amino]methyl]-5-fluoro-3-(4-fluoro-2-methoxyphenyl)-1H-indol-7-amine
Show/Hide
|
C24H23F2N3O
|
1
|
| 1 |
Ki = 4140 nM
|
|
|
|
CP0416882
|
N-[3-(5-fluoro-2-methoxyphenyl)-1H-indol-7-yl]acetamide
Show/Hide
|
C17H15FN2O2
|
1
|
| 1 |
Ki = 6120 nM
|
|
|
|
CP0473332
|
N-[3-(4-cyanophenyl)-1-propan-2-ylindol-6-yl]methanesulfonamide
Show/Hide
|
C19H19N3O2S
|
1
|
| 1 |
Ki > 3900 nM
|
|
|
|
CP0473333
|
N-[3-(4-cyanophenyl)-1-methylindol-6-yl]methanesulfonamide
Show/Hide
|
C17H15N3O2S
|
1
|
| 1 |
Ki > 4020 nM
|
|
|
