Brief Information of the Compound and Protein
Compound Name
4-[7-oxo-4-(1-oxo-3H-2-benzofuran-5-yl)-5-sulfanylidene-4,6-diazaspiro[2.4]heptan-6-yl]-2-(trifluoromethyl)benzonitrile
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Canonical SMILES
FC(F)(F)c1cc(ccc1C#N)N1C(=S)N(c2ccc3C(=O)OCc3c2)C2(CC2)C1=O
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Compound Formula C21H12F3N3O3S
Compound Structure
Protein Name
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 669.6 nM
   TI
   LI
   LO
   TS