General Information of the Compound
| Compound ID |
CP0040191
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| Compound Name |
2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide
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| Synonyms |
2-Hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide
2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
Alpha, alpha, alpha-trifluoro-2-methyl-4'-nitro-m-lactotoluidide
Alpha,alpha,alpha-Trifluoro-2-methyl-4'-nitro-m-lactotoluidide
HFT
Hydroxy-flutamide
Hydroxyflutamide
Hydroxyniphtholide
OH-flutamide
PC1193
Sch 16423
Sch-16423
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| Structure |
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| Formula |
C11H11F3N2O4
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| Molecular Weight |
292.213
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| Canonical SMILES |
CC(C)(O)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O
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| InChI |
InChI=1S/C11H11F3N2O4/c1-10(2,18)9(17)15-6-3-4-8(16(19)20)7(5-6)11(12,13)14/h3-5,18H,1-2H3,(H,15,17)
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| InChIKey |
YPQLFJODEKMJEF-UHFFFAOYSA-N
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| CAS |
52806-53-8
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00894, Androgen receptor
Cell-based Assay
Protein ID: PT01577, Androgen receptor
Protein ID: PT01172, Progesterone receptor
Clinical Information about the Compound