General Information of the Cell Line
Cell Line ID
CL000237
Cell Line Name
22Rv1
Synonyms
22RV1
22Rv-1
22rV1
CWR-22rv1
CWR22-Rv1
CWR22R-V1
CWR22-R1
CWR22Rv1
CWR22R
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1045
Tissue Information
Prostate
Disease
Prostate carcinoma (NCIt: C4863)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT02692, Aldo-keto reductase family 1 member C3
 Protein Info 
Compound ID Compound Name Compound Formula
CP0106946
 Compound Info 
[4-(2-hydroxy-2-methylpropyl)piperidin-1-yl]-(5-methyl-1H-indol-2-yl)methanone
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C19H26N2O2
  1
1
IC50 = 1.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0456265
 Compound Info 
[4-(2-hydroxyethyl)piperidin-1-yl]-(5-methyl-1H-indol-2-yl)methanone
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C17H22N2O2
  1
1
IC50 = 58 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT00894, Androgen receptor
 Protein Info 
Protein ID: PT01566, Histone-lysine N-methyltransferase EHMT2
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0077992
 Compound Info 
[4-(3-chloro-4-fluoroanilino)thieno[2,3-d]pyrimidin-6-yl]-(5-hydroxy-1H-indol-2-yl)methanone
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 C21H12ClFN4O2S  1
1
IC50 = 5610 nM
   TI
   LI
   LO
   TS
CP0095287
 Compound Info 
[4-(3-chloroanilino)thieno[2,3-d]pyrimidin-6-yl]-(1H-indol-2-yl)methanone
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 C21H13ClN4OS  1
1
IC50 = 14000 nM
   TI
   LI
   LO
   TS
CP0341308
 Compound Info 
N-[1-(cyclohexylmethyl)piperidin-4-yl]-6-methoxy-7-(3-piperidin-1-ylpropoxy)-2-(4-propan-2-yl-1,4-diazepan-1-yl)quinazolin-4-amine
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 C37H61N7O2  1
1
EC50 = 2500 nM
   TI
   LI
   LO
   TS
CP0390714
 Compound Info 
2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-[2-(trifluoromethoxy)phenoxy]propanamide
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 C18H14F6N2O6  1
1
IC50 = 6600 nM
   TI
   LI
   LO
   TS
CP0410877
 Compound Info 
3,3,3-trifluoro-2-hydroxy-N-[4-nitro-3-(trifluoromethyl)phenyl]-2-[[2-(trifluoromethyl)phenyl]sulfanylmethyl]propanamide
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 C18H11F9N2O4S  1
1
IC50 = 1277 nM
   TI
   LI
   LO
   TS
CP0412977
 Compound Info 
N-[4-[2-fluoro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]phenyl]heptanamide
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 C22H22F7NO2  1
1
IC50 = 5640 nM
   TI
   LI
   LO
   TS
CP0483514
 Compound Info 
O-[(3S,8R,9S,10R,13S,14S)-17-(benzimidazol-1-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl] imidazole-1-carbothioate
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 C30H34N4OS  1
1
IC50 = 7520 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Prostate)
Cell Line Name Organism Disease
NPrEC
 Cell Line Info 
Homo sapiens (Human) -