General Information of the Cell Line
Cell Line ID
CL000370
Cell Line Name
SC-3
Category
Cancer cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_D3L9
Tissue Information
Mammary gland
Disease
Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01577, Androgen receptor
Compound ID Compound Name Compound Formula
CP0104937
(2S)-3-{4-[1-ethyl-1-(4-{[(2R)-2-hydroxy-3,3-dimethylbutyl]oxy}-3-methylphenyl)propyl]-2-methylphenoxy}propane-1,2-diol
   Show/Hide
C28H42O5
 1
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
CP0216247
1-(4-{1-[4-(2,3-Dihydroxy-propylamino)-3-methyl-phenyl]-1-ethyl-propyl}-2-methyl-phenoxy)-3,3-dimethyl-butan-2-one
   Show/Hide
C28H41NO4
 1
1
IC50 = 7.6 nM
   TI
   LI
   LO
   TS
CP0216246
3-(4-{1-Ethyl-1-[4-(2-hydroxy-3,3-dimethyl-butoxy)-3-methyl-phenyl]-propyl}-2-methyl-phenylamino)-propane-1,2-diol
   Show/Hide
C28H43NO4
 1
1
IC50 = 9 nM
   TI
   LI
   LO
   TS
CP0162322
(S)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol
   Show/Hide
C28H42O5
 1
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
CP0064103
(R)-3-(4-(3-(4-((R)-2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol
   Show/Hide
C28H42O5
 1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
CP0092948
(R)-1-(4-(3-(4-(2,3-dihydroxypropoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)-3,3-dimethylbutan-2-one
   Show/Hide
C28H40O5
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0134848
LG-190178
   Show/Hide
C28H42O5
 1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
CP0146330
(S)-1-(4-(3-(4-(2,3-dihydroxypropoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)-3,3-dimethylbutan-2-one
   Show/Hide
C28H40O5
 1
1
IC50 = 32 nM
   TI
   LI
   LO
   TS
CP0105737
(R)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol
   Show/Hide
C28H42O5
 1
1
IC50 = 68 nM
   TI
   LI
   LO
   TS
CP0392397
(2R)-3-[4-[diethyl-[4-[(2S)-2-hydroxy-3,3-dimethylbutoxy]-3-methylphenyl]silyl]-2-methylphenoxy]propane-1,2-diol
   Show/Hide
C27H42O5Si
 1
1
IC50 = 72 nM
   TI
   LI
   LO
   TS
CP0418099
1-[4-[[4-[(2R)-2,3-dihydroxypropoxy]-3-methylphenyl]-diethylsilyl]-2-methylphenoxy]-3,3-dimethylbutan-2-one
   Show/Hide
C27H40O5Si
 1
1
IC50 = 113 nM
   TI
   LI
   LO
   TS
CP0373634
(2S)-3-(4-(3-(4-(2-hydroxy-3,3-dimethyl-6-phenylhexyloxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol
   Show/Hide
C36H50O5
 1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
CP0040191
2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide
   Show/Hide
C11H11F3N2O4
 2
1
IC50 = 370 nM
   TI
   LI
   LO
   TS
2
IC50 = 1400 nM
   TI
   LI
   LO
   TS
CP0146696
Bicalutamide
   Show/Hide
C18H14F4N2O4S
 2
1
IC50 = 670 nM
   TI
   LI
   LO
   TS
2
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0408556
N-[4-(4-hydroxyphenoxy)-3-methylphenyl]-3-methoxybenzamide
   Show/Hide
C21H19NO4
 1
1
IC50 = 750 nM
   TI
   LI
   LO
   TS
CP0320240
1-(4-{1-Ethyl-1-[4-(3-hydroxy-3-methyl-butylamino)-3-methyl-phenyl]-propyl}-2-methyl-phenoxy)-3,3-dimethyl-butan-2-one
   Show/Hide
C30H45NO3
 1
1
IC50 = 820 nM
   TI
   LI
   LO
   TS
CP0400163
(2S)-3-(4-(3-(4-(2-hydroxy-3,3-dimethyl-5-phenylpentyloxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol
   Show/Hide
C35H48O5
 1
1
IC50 = 880 nM
   TI
   LI
   LO
   TS
CP0172886
1-[4-[3-[4-[(2-hydroxy-3,3-dimethylbutyl)amino]-3-methylphenyl]pentan-3-yl]-2-methylanilino]-3,3-dimethylbutan-2-ol
   Show/Hide
C31H50N2O2
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0180381
1-[4-[3-[4-[(3,3-dimethyl-2-oxobutyl)amino]-3-methylphenyl]pentan-3-yl]-2-methylanilino]-3,3-dimethylbutan-2-one
   Show/Hide
C31H46N2O2
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0405899
(S)-1-(4-(3-(4-(2,3-dihydroxypropoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)-3,3-dimethyl-5-phenylpentan-2-one
   Show/Hide
C35H46O5
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0200347
1-[4-[3-[4-(3,3-dimethyl-2-oxobutoxy)-3-methylphenyl]pentan-3-yl]-2-methylanilino]-3,3-dimethylbutan-2-one
   Show/Hide
C31H45NO3
 1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0373633
(2S)-3-(4-(3-(4-(2-hydroxy-3,3-dimethyl-4-phenylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol
   Show/Hide
C34H46O5
 1
1
IC50 = 1700 nM
   TI
   LI
   LO
   TS
CP0216245
LG190155
   Show/Hide
C31H44O4
 1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0435121
N-[4-(4-hydroxyphenoxy)phenyl]-3-methoxybenzamide
   Show/Hide
C20H17NO4
 1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
CP0461442
N-[4-(4-hydroxyphenoxy)-3,5-dimethylphenyl]-3-methoxybenzamide
   Show/Hide
C22H21NO4
 1
1
IC50 = 2900 nM
   TI
   LI
   LO
   TS
CP0478781
3-(dimethylamino)-N-[4-(4-hydroxyphenoxy)phenyl]benzamide
   Show/Hide
C21H20N2O3
 1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0306007
1-[4-[3-(4-hydroxy-3-methylphenyl)pentan-3-yl]-2-methylanilino]-3,3-dimethylbutan-2-one
   Show/Hide
C25H35NO2
 1
1
IC50 = 3500 nM
   TI
   LI
   LO
   TS
CP0540079
N-[2-(4-hydroxyphenoxy)pyrimidin-5-yl]-3-methoxybenzamide
   Show/Hide
C18H15N3O4
 1
1
IC50 = 5900 nM
   TI
   LI
   LO
   TS
CP0438255
4-(dimethylamino)-N-[4-(4-hydroxyphenoxy)phenyl]benzamide
   Show/Hide
C21H20N2O3
 1
1
IC50 = 6700 nM
   TI
   LI
   LO
   TS
CP0170585
4-(4-{1-Ethyl-1-[4-(3-hydroxy-3-methyl-butylamino)-3-methyl-phenyl]-propyl}-2-methyl-phenylamino)-2-methyl-butan-2-ol
   Show/Hide
C29H46N2O2
 1
1
IC50 = 6800 nM
   TI
   LI
   LO
   TS
CP0476803
N-[6-(4-hydroxyphenoxy)pyridin-3-yl]-3-methoxybenzamide
   Show/Hide
C19H16N2O4
 1
1
IC50 = 7200 nM
   TI
   LI
   LO
   TS
CP0478780
N-[4-(4-hydroxyphenoxy)phenyl]pyridine-2-carboxamide
   Show/Hide
C18H14N2O3
 1
1
IC50 = 8700 nM
   TI
   LI
   LO
   TS
CP0438256
2-hydroxy-N-[4-(4-hydroxyphenoxy)phenyl]benzamide
   Show/Hide
C19H15NO4
 1
1
IC50 = 8800 nM
   TI
   LI
   LO
   TS
CP0554497
N-[4-(4-hydroxyphenoxy)phenyl]benzamide
   Show/Hide
C19H15NO3
 1
1
IC50 = 9400 nM
   TI
   LI
   LO
   TS
CP0476804
N-[4-(4-hydroxyphenoxy)phenyl]pyridine-3-carboxamide
   Show/Hide
C18H14N2O3
 1
1
IC50 = 9700 nM
   TI
   LI
   LO
   TS
CP0502679
(S)-1-(4-(3-(4-(2,3-dihydroxypropoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)-3,3-dimethyl-6-phenylhexan-2-one
   Show/Hide
C36H48O5
 1
1
IC50 = 9800 nM
   TI
   LI
   LO
   TS
CP0377245
(2S)-3-(4-(3-(4-(2-hydroxy-3,3-dimethyl-4-(naphthalen-2-yl)butoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol
   Show/Hide
C38H48O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0377246
(2S)-3-(4-(3-(4-(2-hydroxy-3,3-dimethyl-7-phenylheptyloxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol
   Show/Hide
C37H52O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0386138
(2S)-3-(4-(3-(4-(1-benzyl-4-hydroxypyrrolidin-3-yloxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol
   Show/Hide
C33H43NO5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0388209
(S)-1-(4-(3-(4-(2,3-dihydroxypropoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)-3,3-dimethyl-4-phenylbutan-2-one
   Show/Hide
C34H44O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0519900
(2S)-3-[4-[3-[4-[2-(1-adamantyl)-2-hydroxyethoxy]-3-methylphenyl]pentan-3-yl]-2-methylphenoxy]propane-1,2-diol
   Show/Hide
C34H48O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0379850
N-[4-(4-hydroxyphenoxy)phenyl]-3-nitrobenzamide
   Show/Hide
C19H14N2O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0424503
N-(4-phenoxyphenyl)benzamide
   Show/Hide
C19H15NO2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0435126
N-[4-(4-hydroxyphenoxy)phenyl]-4-nitrobenzamide
   Show/Hide
C19H14N2O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0476805
N-[4-(4-hydroxyphenoxy)phenyl]-2-nitrobenzamide
   Show/Hide
C19H14N2O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0492999
N-[4-(4-hydroxyphenoxy)phenyl]pyridine-4-carboxamide
   Show/Hide
C18H14N2O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0493004
N-[4-(4-hydroxyphenoxy)phenyl]-2-methoxybenzamide
   Show/Hide
C20H17NO4
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0554496
N-[4-(4-hydroxyphenoxy)phenyl]-4-methoxybenzamide
   Show/Hide
C20H17NO4
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0377244
1-(1-adamantyl)-2-[4-[3-[4-[(2S)-2,3-dihydroxypropoxy]-3-methylphenyl]pentan-3-yl]-2-methylphenoxy]ethanone
   Show/Hide
C34H46O5
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0386137
(S)-1-(4-(3-(4-(2,3-dihydroxypropoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)-3,3-dimethyl-4-(naphthalen-2-yl)butan-2-one
   Show/Hide
C38H46O5
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0400164
benzyl (3R,4S)-3-[4-[3-[4-[(2S)-2,3-dihydroxypropoxy]-3-methylphenyl]pentan-3-yl]-2-methylphenoxy]-4-hydroxypyrrolidine-1-carboxylate
   Show/Hide
C34H43NO7
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0519898
(S)-1-(4-(3-(4-(2,3-dihydroxypropoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)-3,3-dimethyl-7-phenylheptan-2-one
   Show/Hide
C37H50O5
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Mammary gland)
Cell Line Name Organism Disease
4T1 Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
EMT6 Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
SC-115 Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
C127 Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
NMU Rattus norvegicus (Rat) Adenocarcinoma of the rat mammary gland
HC11 Mus musculus (Mouse) -