General Information of the Cell Line
Cell Line ID
CL000245
Cell Line Name
4T1
Synonyms
4T1-A
4T1.0
4T1/WT
Category
Cancer cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0125
Tissue Information
Mammary gland
Disease
Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT04556, TGF-beta receptor type-1
 Protein Info 
Compound ID Compound Name Compound Formula
CP0055625
 Compound Info 
2-fluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline
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C22H18FN7
  1
1
IC50 = 12.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0173805
 Compound Info 
3-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-yl)methyl)benzamide
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C25H20N6O
  1
1
IC50 = 44.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0015550
 Compound Info 
2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridine
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C20H21N3O2
  1
1
IC50 = 76.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0010529
 Compound Info 
GALUNISERTIB
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C22H19N5O
  1
1
IC50 > 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Mammary gland)
Cell Line Name Organism Disease
SC-3
 Cell Line Info 
Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
EMT6
 Cell Line Info 
Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
SC-115
 Cell Line Info 
Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
C127
 Cell Line Info 
Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
NMU
 Cell Line Info 
Rattus norvegicus (Rat) Adenocarcinoma of the rat mammary gland
HC11
 Cell Line Info 
Mus musculus (Mouse) -