General Information of the Cell Line
Cell Line ID
CL000564
Cell Line Name
EMT6
Synonyms
EMT-6
Experimental Mammary Tumour-6
Category
Cancer cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_1923
Tissue Information
Mammary gland
Disease
Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT05905, 5'-nucleotidase
 Protein Info 
Compound ID Compound Name Compound Formula
CP0426496
 Compound Info 
[(2R)-2-[[(2R,3S,4R,5R)-5-[6-chloro-4-(cyclopentylamino)pyrazolo[3,4-d]pyrimidin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxy]-1-hydroxy-3-methoxypropan-2-yl]phosphonic acid
   Show/Hide
C19H29ClN5O9P
  1
1
EC50 = 14 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0426495
 Compound Info 
[(2R)-2-[[(2R,3S,4R,5R)-5-[6-chloro-4-(cyclopentylamino)pyrazolo[3,4-d]pyrimidin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxy]-1-hydroxypropan-2-yl]phosphonic acid
   Show/Hide
C18H27ClN5O8P
  1
1
EC50 = 41 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0466407
 Compound Info 
[2-[[(2R,3S,4R,5R)-5-[6-chloro-4-(cyclopentylamino)pyrazolo[3,4-d]pyrimidin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxy]-1,3-dihydroxypropan-2-yl]phosphonic acid
   Show/Hide
C18H27ClN5O9P
  1
1
EC50 = 46 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0135378
 Compound Info 
[[(2R,3S,4R,5R)-5-[6-chloro-4-[[(1S)-1-(2-fluorophenyl)ethyl]amino]pyrazolo[3,4-b]pyridin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]methylphosphonic acid
   Show/Hide
C20H24ClFN4O9P2
  1
1
EC50 = 198 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0435681
 Compound Info 
US8686018, 107
   Show/Hide
 C22H18F5N3O4  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Mammary gland)
Cell Line Name Organism Disease
4T1
 Cell Line Info 
Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
SC-3
 Cell Line Info 
Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
SC-115
 Cell Line Info 
Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
C127
 Cell Line Info 
Mus musculus (Mouse) Malignant neoplasms of the mouse mammary gland
NMU
 Cell Line Info 
Rattus norvegicus (Rat) Adenocarcinoma of the rat mammary gland
HC11
 Cell Line Info 
Mus musculus (Mouse) -