Brief Information of the Compound and Protein
Compound Name
2-fluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline
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PubChem ID
CID: 54766013
SID: 131530595
Canonical SMILES
Cc1cccc(n1)-c1[nH]c(CNc2ccccc2F)nc1-c1ccc2ncnn2c1
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Compound Formula C22H18FN7
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase STKR family
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TKL protein kinase STKR Type 1 subfamily
Uniprot ID
Q64729
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000245 4T1 Mus musculus (Mouse)  1
1
IC50 = 12.1 nM
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