Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10806720, Compound 1002
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 PubChem ID
CID: 132214622
Canonical SMILES
C[C@](O)(Cn1cc(F)cn1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F
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Compound Formula C15H12F4N4O2
Compound Structure
Protein Name
 Protein Info 
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000880 COS
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 219 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 199 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2000 nM