Brief Information of the Compound and Protein
Compound Name
 Compound Info 
956104-40-8
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 PubChem ID
CID: 24872560
SID: 50127665
Canonical SMILES
CNC(=O)c1ccc(cc1F)N1C(=S)N(C(=O)C11CCC1)c1cnc(C#N)c(c1)C(F)(F)F
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Compound Formula C21H15F4N5O2S
Compound Structure
Protein Name
 Protein Info 
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
2
IC50 = 160 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 200 nM
2 Ki = 34.7 nM
3 Ki = 93 nM
4 Ki = 1452 nM