Brief Information of the Compound and Protein
Compound Name
(2S)-N-(3-chloro-4-cyanophenyl)-3-(5-fluoro-6-phenylindol-1-yl)-2-hydroxy-2-methylpropanamide
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PubChem ID
CID: 122640109
Canonical SMILES
C[C@](O)(Cn1ccc2cc(F)c(cc12)-c1ccccc1)C(=O)Nc1ccc(C#N)c(Cl)c1
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Compound Formula C25H19ClFN3O2
Compound Structure
Protein Name
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 203 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 133 nM