Brief Information of the Compound and Protein
Compound Name
4-[4,4-dimethyl-5-oxo-3-(1-oxo-3,4-dihydroisochromen-6-yl)-2-sulfanylideneimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
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Canonical SMILES
CC1(C)N(C(=S)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F)c1ccc2C(=O)OCCc2c1
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Compound Formula C22H16F3N3O3S
Compound Structure
Protein Name
Androgen receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 195.5 nM
   TI
   LI
   LO
   TS