General Information of the Compound
| Compound ID |
CP0217093
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| Compound Name |
Enobosarm
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| Synonyms |
(2R)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
(R)-N-(4-Cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide
(R)-Ostarine
1132656-73-5
370C134
841205-47-8 pound not1202044-20-9
AOB87717
AS-17044
BCP9001038
BCPP000135
BRD-K16621777-001-01-9
C19H14F3N3O3
CHEBI:94527
DTXSID70649384
FT-0673314
GTx-024
I06-2154
NCGC00408913-01
SCHEMBL2197534
Y0247
ZINC35793633
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| Structure |
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| Formula |
C19H14F3N3O3
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| Molecular Weight |
389.333
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| Canonical SMILES |
C[C@](O)(COc1ccc(cc1)C#N)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F
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| InChI |
InChI=1S/C19H14F3N3O3/c1-18(27,11-28-15-6-2-12(9-23)3-7-15)17(26)25-14-5-4-13(10-24)16(8-14)19(20,21)22/h2-8,27H,11H2,1H3,(H,25,26)/t18-/m0/s1
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| InChIKey |
JNGVJMBLXIUVRD-SFHVURJKSA-N
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| CAS |
841205-47-8
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00894, Androgen receptor
Protein ID: PT01486, Androgen receptor
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000141 | LNCaP | Homo sapiens (Human) | 1 |
| 1 |
IC50 = 20900 nM
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| CL000700 | VCaP | Homo sapiens (Human) | 1 |
| 1 |
IC50 = 24470 nM
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LO
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Clinical Information about the Compound