Protein Information

General Information of the Protein

Protein ID	PT03549
Protein Name	C-C chemokine receptor type 9
Secondarily Protein Name	G-protein coupled receptor 28 GPR-9-6
Gene Name	CCR9
Secondarily Gene Name	GPR28
Sequence	MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFIVGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCKVVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALCIPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHTLIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQVTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLLETTSGALSL Show/Hide
Organism	Homo sapiens, Human
Protein Classification	Membrane receptor > Family A G protein-coupled receptor > Peptide receptor (family A GPCR) > Chemokine receptor > CC chemokine receptor
Function	Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level. Show/Hide
Uniprot ID	Primary ID: P51686 Secondarily ID: Q4VBM3 Q549E0 Q9UQQ6 Show/Hide
Ensembl ID	ENSG00000173585
HGNC ID	HGNC:1610
Subcellular Location	Cell membrane

Map of Molecular Bioactivity Related to the Protein

Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Protein

Cell Line ID: CL000116 , MOLT-4

Cell Line Info

Compound ID	Compound Name	Compound Formula
CP0109129 Compound Info	4-tert-butyl-N-[4-chloro-2-(1-oxidopyridin-1-ium-4-carbonyl)phenyl]benzenesulfonamide Show/Hide	C22H21ClN2O4S	5
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
3	Ki = 1.1 nM Bioactivity Info	TI LI LO TS
4	Ki = 3.7 nM Bioactivity Info	TI LI LO TS
5	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0848996 Compound Info	N-(4-bromo-2-(pyridine-4-carbonyl)phenyl)-4-tert-butylbenzenesulfonamide Show/Hide	C22H21BrN2O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0848998 Compound Info	N-(4-chloro-2-(2-methyl-pyridine-4-carbonyl)phenyl)-4-(trifluoromethoxy)benzenesulfonamide Show/Hide	C20H14ClF3N2O4S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0849002 Compound Info	N-(4-chloro-2-(2-methyl-pyridine-3-carbonyl)phenyl)-4-isopropoxybenzenesulfonamide Show/Hide	C22H21ClN2O4S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0849005 Compound Info	N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)-4-tert-pentylbenzenesulfonamide Show/Hide	C23H23ClN2O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0849008 Compound Info	N-[4-Chloro-2-(6-methyl-1-oxy-pyridine-3-carbonyl)-phenyl]-4-trifluoromethoxy-benzenesulfonamide Show/Hide	C20H14ClF3N2O5S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0849011 Compound Info	N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)-4-(2,4-dimethyloxazol-5-yl)benzenesulfonamide Show/Hide	C23H18ClN3O4S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0849013 Compound Info	N-(4-chloro-2-(pyridine-3-carbonyl)phenyl)-4-(oxazol-4-yl)benzenesulfonamide Show/Hide	C21H14ClN3O4S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0850706 Compound Info	4-(5-chloro-2-(4-(oxazol-5-yl)phenylsulfonamido)benzoyl)pyridine 1-oxide Show/Hide	C21H14ClN3O5S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0850707 Compound Info	2-(4-(N-(4-chloro-2-(pyridine4-4-carbonyl)phenyl)sulfamoyl)phenyl)-2-methylpropyl acetate Show/Hide	C24H23ClN2O5S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0850708 Compound Info	N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)-4-methylbenzenesulfonamide Show/Hide	C19H15ClN2O3S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0850710 Compound Info	4-tert-butyl-N-(4-chloro-2-(pyrimidine-4-carbonyl)phenyl)benzenesulfonamide Show/Hide	C21H20ClN3O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0850711 Compound Info	N-(4-chloro-2-(2-methyl-pyridine-3-carbonyl)phenyl)-4-(methylsulfonyl)benzenesulfonamide Show/Hide	C20H17ClN2O5S2	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0850719 Compound Info	N-[4-Chloro-2-(2-methyl-1-oxy-pyridine-3-carbonyl)-phenyl]-4-isopropoxy-benzenesulfonamide Show/Hide	C22H21ClN2O5S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0858009 Compound Info	4-tert-butyl-N-(4-chloro-2-(pyridine-2-carbonyl)phenyl)benzenesulfonamide Show/Hide	C22H21ClN2O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0858011 Compound Info	4-tert-butyl-N-(4,5-difluoro-2-(pyridine-4-carbonyl)phenyl)benzenesulfonamide Show/Hide	C22H20F2N2O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0858012 Compound Info	4-tert-butyl-N-(4-chloro-2-(6-methyl-pyridine-3-carbonyl)phenyl)benzenesulfonamide Show/Hide	C23H23ClN2O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0858013 Compound Info	N-(4-bromo-2-(pyridine-4-carbonyl)phenyl)-4-isopropoxybenzenesulfonamide Show/Hide	C21H19BrN2O4S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0858014 Compound Info	4-tert-butyl-N-(4-chloro-2-(6-methyl-pyridine-2-carbonyl)phenyl)benzenesulfonamide Show/Hide	C23H23ClN2O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0858034 Compound Info	N-(4-chloro-2-(2-methyl-pyridine-3-carbonyl)phenyl)-4-(trifluoromethoxy)benzenesulfonamide Show/Hide	C20H14ClF3N2O4S	1
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
CP0858035 Compound Info	4-tert-butyl-N-(4-chloro-2-(6-(methylsulfonyl)pyridine-3-carbonyl)phenyl)benzenesulfonamide Show/Hide	C23H23ClN2O5S2	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0858036 Compound Info	4-tert-butyl-N-(4-chloro-2-(2-methoxy-pyridine-4-carbonyl)phenyl)benzenesulfonamide Show/Hide	C23H23ClN2O4S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0861678 Compound Info	4-tert-butyl-N-(4-chloro-2-(2-methyl-pyridine-4-carbonyl)phenyl)benzenesulfonamide Show/Hide	C23H23ClN2O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0861679 Compound Info	4-tert-butyl-N-(4-chloro-2-(6-(methylthio)pyridine-3-carbonyl)phenyl)benzenesulfonamide Show/Hide	C23H23ClN2O3S2	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0865029 Compound Info	N-(4-chloro-2-(2-methyl-pyridine-4-carbonyl)phenyl)-4-(oxazol-5-yl)benzenesulfonamide Show/Hide	C22H16ClN3O4S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0865030 Compound Info	4-tert-butyl-N-(3,4-difluoro-2-(pyridine-4-carbonyl)phenyl)benzenesulfonamide Show/Hide	C22H20F2N2O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866063 Compound Info	N-(4-chloro-2-(pyridine-3-carbonyl)phenyl)-4-(oxazol-5-yl)benzenesulfonamide Show/Hide	C21H14ClN3O4S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866400 Compound Info	5-(5-chloro-2-(4-(3-methoxy-3-oxopropyl)phenylsulfonamido)benzoyl)-2-methylpyridine 1-oxide Show/Hide	C23H21ClN2O6S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866408 Compound Info	N-[4-Chloro-2-(2-methyl-1-oxy-pyridine-4-carbonyl)-phenyl]-4-trifluoromethoxy-benzenesulfonamide Show/Hide	C20H14ClF3N2O5S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866410 Compound Info	methyl 3-(4-(N-(4-chloro-2-(pyridine-3-carbonyl)phenyl)sulfamoyl)phenyl)propanoate Show/Hide	C22H19ClN2O5S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866411 Compound Info	4-tert-butyl-N-(5-chloro-2-(pyridine-4-carbonyl)phenyl)benzenesulfonamide Show/Hide	C22H21ClN2O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866414 Compound Info	N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)-4-(oxazol-5-yl)benzenesulfonamide Show/Hide	C21H14ClN3O4S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866415 Compound Info	N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)-4-(trifluoromethoxy)benzenesulfonamide Show/Hide	C19H12ClF3N2O4S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0867455 Compound Info	N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)-4-methoxybenzenesulfonamide Show/Hide	C19H15ClN2O4S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0880968 Compound Info	5-(2-(4-tert-butylphenylsulfonamido)-5-chlorobenzoyl)-2-methylpyridine 1-oxide Show/Hide	C23H23ClN2O4S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0894520 Compound Info	4-tert-butyl-N-(4-chloro-2-(pyridine-3-carbonyl)phenyl)benzenesulfonamide Show/Hide	C22H21ClN2O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0896504 Compound Info	N-(4-chloro-2-(6-chloro-pyridine-3-carbonyl)phenyl)-4-(trifluoromethoxy)benzenesulfonamide Show/Hide	C19H11Cl2F3N2O4S	1
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
CP0918239 Compound Info	N-(4-chloro-2-(pyridine-2-carbonyl)phenyl)-4-methoxybenzenesulfonamide Show/Hide	C19H15ClN2O4S	1
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
CP0926532 Compound Info	N-[4-Chloro-2-(2-methyl-1-oxy-pyridine-4-carbonyl)-phenyl]-4-isopropoxy-benzenesulfonamide Show/Hide	C22H21ClN2O5S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0940837 Compound Info	N-(4-chloro-2-(4-methylbenzoyl)phenyl)-4-(oxazol-5-yl)benzenesulfonamide Show/Hide	C23H17ClN2O4S	1
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
CP0952192 Compound Info	4-tert-Butyl-N-[4-chloro-2-(1-oxy-pyridine-3-carbonyl)-phenyl]benzenesulfonamide Show/Hide	C22H21ClN2O4S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0849000 Compound Info	N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)biphenyl-4-sulfonamide Show/Hide	C24H17ClN2O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0849009 Compound Info	N-[4-Chloro-2-(6-methyl-1-oxy-pyridine-3-carbonyl)-phenyl]-4-isopropoxy-benzenesulfonamide Show/Hide	C22H21ClN2O5S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0849010 Compound Info	4-tert-butyl-N-(4-chloro-2-(pyridine-4-carbonyl)-3-methoxyphenyl)benzenesulfonamide Show/Hide	C23H23ClN2O4S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0849017 Compound Info	N-(4-chloro-2-(pyridine-3-carbonyl)phenyl)-4-isopropoxybenzenesulfonamide Show/Hide	C21H19ClN2O4S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0849020 Compound Info	N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)-4-ethylbenzenesulfonamide Show/Hide	C20H17ClN2O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0857791 Compound Info	methyl 3-(4-(N-(4-chloro-2-(2-methyl-pyridine-4-carbonyl)phenyl)sulfamoyl)phenyl)propanoate Show/Hide	C23H21ClN2O5S	1
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
CP0857792 Compound Info	4-tert-Butyl-N-[4-chloro-2-methyl-1-oxy-pyridine-3-carbonyl)-phenyl]-benzenesulfonamide Show/Hide	C23H23ClN2O4S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0857793 Compound Info	4-tert-butyl-N-(4-chloro-2-(2-methyl-pyridine-3-carbonyl)phenyl)benzenesulfonamide Show/Hide	C23H23ClN2O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0858010 Compound Info	4-tert-butyl-N-(2-chloro-6-(pyridine-4-carbonyl)phenyl)benzenesulfonamide Show/Hide	C22H21ClN2O3S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0858016 Compound Info	N-(4-chloro-2-(pyrimidine-2-carbonyl)phenyl)-4-(oxazol-5-yl)benzenesulfonamide Show/Hide	C20H13ClN4O4S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0858017 Compound Info	methyl 3-(4-(N-(4-chloro-2-(6-methyl-pyridine-3-carbonyl)phenyl)sulfamoyl)phenyl)propanoate Show/Hide	C23H21ClN2O5S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0858018 Compound Info	4-tert-butyl-N-(4-chloro-2-(2-(methylthio)pyridine-4-carbonyl)phenyl)benzenesulfonamide Show/Hide	C23H23ClN2O3S2	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0858019 Compound Info	4-bromo-N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)benzenesulfonamide Show/Hide	C18H12BrClN2O3S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0858020 Compound Info	N-(4-bromo-2-(pyridine-4-carbonyl)phenyl)-4-(trifluoromethoxy)benzenesulfonamide Show/Hide	C19H12BrF3N2O4S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0858021 Compound Info	N-(4-chloro-2-(6-methyl-pyridine-3-carbonyl)phenyl)-4-(methylsulfonyl)benzenesulfonamide Show/Hide	C20H17ClN2O5S2	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0858022 Compound Info	N-(4-chloro-2-(pyridine-3-carbonyl)phenyl)-4-(methylsulfonyl)benzenesulfonamide Show/Hide	C19H15ClN2O5S2	1
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
CP0859833 Compound Info	2-(2-(4-tert-butylphenylsulfonamido)-5-chlorobenzoyl)pyridine 1-oxide Show/Hide	C22H21ClN2O4S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0859834 Compound Info	N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)-1,2,3,4-tetrahydroisoquinoline-7-sulfonamide Show/Hide	C21H18ClN3O3S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0859843 Compound Info	4-tert-butyl-N-(4-chloro-2-(2-chloro-pyridine-4-carbonyl)phenyl)benzenesulfonamide Show/Hide	C22H20Cl2N2O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0859844 Compound Info	N-(4-chloro-2-(6-methyl-pyridine-3-carbonyl)phenyl)-4-isopropoxybenzenesulfonamide Show/Hide	C22H21ClN2O4S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0859845 Compound Info	N-(4-bromo-2-(2-(methylsulfonyl)pyridine-4-carbonyl)phenyl)-4-tert-butylbenzenesulfonamide Show/Hide	C23H23BrN2O5S2	1
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
CP0861402 Compound Info	N-(4-bromo-2-(pyridine-4-carbonyl)phenyl)-4-(methylsulfonyl)benzenesulfonamide Show/Hide	C19H15BrN2O5S2	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0861404 Compound Info	4-(5-chloro-2-(4-(1-hydroxy-2-methylpropan-2-yl)phenylsulfonamido)benzoyl)pyridine 1-oxide Show/Hide	C22H21ClN2O5S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0861680 Compound Info	N-(4-bromo-2-(pyridine-4-carbonyl)phenyl)-4-ethylbenzenesulfonamide Show/Hide	C20H17BrN2O3S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0862325 Compound Info	4-tert-butyl-N-(4-chloro-2-(2-cyano(pyridine-4-carbonyl))phenyl)benzenesulfonamide Show/Hide	C23H20ClN3O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866420 Compound Info	4-tert-butyl-N-(4-chloro-2-(pyrimidine-2-carbonyl)phenyl)benzenesulfonamide Show/Hide	C21H20ClN3O3S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0867456 Compound Info	N-(4-chloro-2-(2-methyl-pyridine-4-carbonyl)phenyl)-4-isopropoxybenzenesulfonamide Show/Hide	C22H21ClN2O4S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0867457 Compound Info	N-(4-chloro-2-(3-methylbenzoyl)phenyl)-4-(oxazol-5-yl)benzenesulfonamide Show/Hide	C23H17ClN2O4S	1
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
CP0867458 Compound Info	N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)-4-isopropoxybenzenesulfonamide Show/Hide	C21H19ClN2O4S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0880969 Compound Info	N-(4-chloro-2-(pyridine-3-carbonyl)phenyl)-4-(trifluoromethoxy)benzenesulfonamide Show/Hide	C19H12ClF3N2O4S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0880970 Compound Info	2-chloro-5-(5-chloro-2-(4-(methylsulfonyl)phenylsulfonamido)benzoyl)pyridine 1-oxide Show/Hide	C19H14Cl2N2O6S2	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0880971 Compound Info	4-tert-butyl-N-(4-fluoro-2-(pyridine-4-carbonyl)phenyl)benzenesulfonamide Show/Hide	C22H21FN2O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0902168 Compound Info	N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide Show/Hide	C22H21ClN2O4S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0902231 Compound Info	4-tert-butyl-N-(4-chloro-2-(pyrazine-2-carbonyl)phenyl)benzenesulfonamide Show/Hide	C21H20ClN3O3S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0902240 Compound Info	4-tert-butyl-N-(4-chloro-2-(6-chloro-pyridine-3-carbonyl)phenyl)benzenesulfonamide Show/Hide	C22H20Cl2N2O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0902247 Compound Info	4-tert-butyl-N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)benzenesulfonamide Show/Hide	C22H21ClN2O3S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0903294 Compound Info	4-(2-(4-tert-butylphenylsulfonamido)-5-chlorobenzoyl)-2-chloropyridine 1-oxide Show/Hide	C22H20Cl2N2O4S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0903309 Compound Info	4-(2-(4-tert-butylphenylsulfonamido)-5-chlorobenzoyl)-2-methylpyridine 1-oxide Show/Hide	C23H23ClN2O4S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0904280 Compound Info	5-(5-chloro-2-(4-(methylsulfonyl)phenylsulfonamido)benzoyl)-2-methylpyridine 1-oxide Show/Hide	C20H17ClN2O6S2	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0914032 Compound Info	N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)-4-nitrobenzenesulfonamide Show/Hide	C18H12ClN3O5S	1
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
CP0914932 Compound Info	4-tert-butyl-N-(4-chloro-2-(2-(methylsulfonyl)pyridine-4-carbonyl)phenyl)benzenesulfonamide Show/Hide	C23H23ClN2O5S2	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0951854 Compound Info	methyl 3-(4-(N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)sulfamoyl)phenyl)propanoate Show/Hide	C22H19ClN2O5S	2
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0952130 Compound Info	4-acetyl-N-(4-bromo-2-(pyridine-4-carbonyl)phenyl)benzenesulfonamide Show/Hide	C20H15BrN2O4S	1
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
CP0952193 Compound Info	methyl 3-(4-(N-(4-chloro-2-(2-methyl-pyridine-3-carbonyl)phenyl)sulfamoyl)phenyl)propanoate Show/Hide	C23H21ClN2O5S	2
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
2	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0967877 Compound Info	N-(4-chloro-2-(2-methyl-pyridine-4-carbonyl)phenyl)-4-(methylsulfonyl)benzenesulfonamide Show/Hide	C20H17ClN2O5S2	1
1	IC50 < 100 nM Bioactivity Info	TI LI LO TS
CP0240491 Compound Info	6-chloro-1-[[4-(1-methoxy-2-methylpropan-2-yl)phenyl]methyl]pyrrolo[3,2-b]pyridine-2-carboxylic acid Show/Hide	C20H21ClN2O3	1
1	IC50 = 218 nM Bioactivity Info	TI LI LO TS
CP0190640 Compound Info	1-[(4-tert-butylphenyl)methyl]-6-chloropyrrolo[3,2-b]pyridine-2-carboxylic acid Show/Hide	C19H19ClN2O2	1
1	IC50 = 277 nM Bioactivity Info	TI LI LO TS
CP0068011 Compound Info	6-chloro-1-[[4-(trifluoromethyl)phenyl]methyl]pyrrolo[3,2-b]pyridine-2-carboxylic acid Show/Hide	C16H10ClF3N2O2	1
1	IC50 = 590 nM Bioactivity Info	TI LI LO TS
CP0848991 Compound Info	4-tert-butyl-N-(2-pyridine-4-carbonyl-4-(pyrrolidin-1-ylsulfonyl)phenyl)benzenesulfonamide Show/Hide	C26H29N3O5S2	2
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
2	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0848992 Compound Info	N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)-4-(trifluoromethyl)benzenesulfonamide Show/Hide	C19H12ClF3N2O3S	2
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
2	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0850705 Compound Info	N-(4-chloro-2-(6-methyl-pyridine-2-carbonyl)phenyl)-4-(2-methyloxazol-5-yl)benzenesulfonamide Show/Hide	C23H18ClN3O4S	2
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
2	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0858032 Compound Info	3-(4-(N-(4-chloro-2-(4-methylbenzoyl)phenyl)sulfamoyl)phenyl)-N,N-dimethylpropanamide Show/Hide	C25H25ClN2O4S	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0858033 Compound Info	3-(4-(N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)sulfamoyl)phenyl)-N,N-dimethylpropanamide Show/Hide	C23H22ClN3O4S	2
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
2	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0866401 Compound Info	4-acetyl-N-(4-chloro-2-(6-methylnicotinoyl)phenyl)benzenesulfonamide Show/Hide	C21H17ClN2O4S	2
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
2	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0914021 Compound Info	N-(4-chloro-2-(pyrimidine-4-carbonyl)phenyl)-4-(oxazol-5-yl)benzenesulfonamide Show/Hide	C20H13ClN4O4S	2
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
2	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0949199 Compound Info	N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)-4-(methylsulfonyl)benzenesulfonamide Show/Hide	C19H15ClN2O5S2	2
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
2	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0951880 Compound Info	4-acetyl-N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)benzenesulfonamide Show/Hide	C20H15ClN2O4S	2
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
2	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0952986 Compound Info	N-(4-bromo-2-(pyridine-4-carbonyl)phenyl)-4-methoxybenzenesulfonamide Show/Hide	C19H15BrN2O4S	2
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
2	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0858015 Compound Info	N-(4-chloro-2-(1-methyl-1H-imidazole-2-carbonyl)phenyl)-4-methoxybenzenesulfonamide Show/Hide	C18H16ClN3O4S	2
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
2	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0866083 Compound Info	4-tert-butyl-N-(4-chloro-2-(6-morpholino-pyridine-3-carbonyl)phenyl)benzenesulfonamide Show/Hide	C26H28ClN3O4S	2
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
2	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0866084 Compound Info	4-(2-(4-tert-butylphenylsulfonamido)-5-(pyrrolidin-1-ylsulfonyl)benzoyl)pyridine 1-oxide Show/Hide	C26H29N3O6S2	2
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
2	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0866418 Compound Info	4-chloro-N-(4-chloro-2-(pyridine-3-carbonyl)phenyl)benzenesulfonamide Show/Hide	C18H12Cl2N2O3S	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0880964 Compound Info	4-acetyl-N-(4-chloro-2-(2-methyl-pyridine-4-carbonyl)phenyl)benzenesulfonamide Show/Hide	C21H17ClN2O4S	2
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
2	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0902230 Compound Info	N-(4-chloro-2-(2-methyl-pyridine-3-carbonyl)phenyl)-4-(oxazol-5-yl)benzenesulfonamide Show/Hide	C22H16ClN3O4S	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0914930 Compound Info	2-(4-(N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)sulfamoyl)phenyl)-N,N,2-trimethylpropanamide Show/Hide	C24H24ClN3O4S	2
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
2	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0914931 Compound Info	N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)-3-(5-methyl-1,3,4-oxadiazol-2-yl)benzenesulfonamide Show/Hide	C21H15ClN4O4S	2
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
2	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0190641 Compound Info	6-chloro-1-[[4-(4-methyloxan-4-yl)phenyl]methyl]pyrrolo[3,2-b]pyridine-2-carboxylic acid Show/Hide	C21H21ClN2O3	1
1	IC50 = 1050 nM Bioactivity Info	TI LI LO TS
CP0190639 Compound Info	1-[(4-tert-butylphenyl)methyl]-6-chloroindole-2-carboxylic acid Show/Hide	C20H20ClNO2	1
1	IC50 = 1365 nM Bioactivity Info	TI LI LO TS
CP0329147 Compound Info	1-[(4-tert-butylphenyl)methyl]-5-chloropyrrolo[2,3-c]pyridine-2-carboxylic acid Show/Hide	C19H19ClN2O2	1
1	IC50 = 2600 nM Bioactivity Info	TI LI LO TS
CP0133635 Compound Info	1-[(4-tert-butylphenyl)methyl]-6-chloropyrrolo[3,2-c]pyridine-2-carboxylic acid Show/Hide	C19H19ClN2O2	1
1	IC50 = 5400 nM Bioactivity Info	TI LI LO TS
CP0848985 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-(2-(2-oxopiperidin-1-yl)propan-2-yl)benzenesulfonamide Show/Hide	C26H26ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0848987 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-(oxazol-2-yl)benzenesulfonamide Show/Hide	C21H14ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0848989 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-(3,5-dimethylisoxazol-4-yl)benzenesulfonamide Show/Hide	C23H18ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0848993 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-(thiazol-2-yl)benzenesulfonamide Show/Hide	C21H14ClN3O3S2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0848994 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-(piperazin-1-yl)benzenesulfonamide Show/Hide	C22H21ClN4O3S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0848995 Compound Info	N-(2-(3-benzylpiperidine-1-carbonyl)-4-chlorophenyl)-4-methoxybenzenesulfonamide Show/Hide	C26H27ClN2O4S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0850479 Compound Info	N-(4-bromo-2-isonicotinoylphenyl)-4-isopropylbenzenesulfonamide Show/Hide	C21H19BrN2O3S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0850709 Compound Info	2-{4-[4-Chloro-2-(pyridine-4-carbonyl)-phenylsulfamoyl]-phenyl}-pyrrole-1-carboxylic acid tert-butyl ester Show/Hide	C27H24ClN3O5S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0860076 Compound Info	N-[4-Chloro-2-(pyridine-3-carbonyl)-phenyl]-4-(1-methyl-1-oxazol-2-yl-ethyl)-benzenesulfonamide Show/Hide	C24H20ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0862322 Compound Info	N-[4-Chloro-2-(pyridine4-carbonyl)-phenyl]-3-fluoro-4-morpholin4-yl-benzenesulfonamide Show/Hide	C22H19ClFN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866308 Compound Info	N-(4-chloro-2-(1H-pyrazole-3-carbonyl)phenyl)-3-fluoro-4-(4-methyltetrahydro-2H-pyran-4-yl)benzenesulfonamide Show/Hide	C22H21ClFN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866309 Compound Info	N-[4-Chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-4-morpholin-4-yl-3-fluorobenzenesulfonamide Show/Hide	C22H19ClFN3O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866310 Compound Info	N-(4-chloro-2-(2-methylisonicotinoyl)phenyl)-4-(4-methyl-tetrahydro-2H-pyran-4-yl)benzenesulfonamide Show/Hide	C25H25ClN2O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0867426 Compound Info	4-(5-chloro-2-(4-(2-(oxazol-2-yl)propan-2-yl)phenylsulfonamido)benzoyl)pyridine 1-oxide Show/Hide	C24H20ClN3O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0867427 Compound Info	N-[4-Chloro-2-(pyridine-3-carbonyl)-phenyl]-4-(4-methyl-tetrahydropyran-4-yl)-benzenesulfonamide Show/Hide	C24H23ClN2O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0867428 Compound Info	N-[4-Chloro-2-(pyridine-4-carbonyl)-phenyl]-4-(cis-2,6-dimethyl-morpholin-4-yl)-3-fluorobenzenesulfonamide Show/Hide	C24H23ClFN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0867429 Compound Info	N-[4-Chloro-2-(6-methylpyridine-3-carbonyl)-phenyl]-4-(1-methyl-1-oxazol-4-yl-ethyl)-benzenesulfonamide Show/Hide	C25H22ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0867430 Compound Info	N-(4-chloro-2-(6-methylnicotinoyl)phenyl)-4-(2-(oxazol-2-yl)propan-2-yl)benzenesulfonamide Show/Hide	C25H22ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0867431 Compound Info	4-(5-chloro-2-(4-(furan-3-yl)phenylsulfonamido)benzoyl)pyridine 1-oxide Show/Hide	C22H15ClN2O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0867432 Compound Info	N-(4-chloro-2-(6-methylnicotinoyl)phenyl)-4-(2-(oxazol-5-yl)propan-2-yl)benzenesulfonamide Show/Hide	C25H22ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0867433 Compound Info	4-tert-butyl-N-(4-chloro-2-(thiazole-2-carbonyl)phenyl)benzenesulfonamide Show/Hide	C20H19ClN2O3S2	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0867700 Compound Info	N-[4,5-Difluoro-2-(pyridine-3-carbonyl)-phenyl]-4-morpholin-4-yl-benzenesulfonamide Show/Hide	C22H19F2N3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0867701 Compound Info	5-(5-chloro-2-(4-(2-(oxazol-2-yl)propan-2-yl)phenylsulfonamido)benzoyl)-2-methylpyridine 1-oxide Show/Hide	C25H22ClN3O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0868022 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-((2,4-dimethyl-1,3-dioxolan-2-yl)methyl)benzenesulfonamide Show/Hide	C24H23ClN2O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0874181 Compound Info	N-(4-chloro-2-(6-methylnicotinoyl)phenyl)-4-(4-methyloxazol-5-yl)benzenesulfonamide Show/Hide	C23H18ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0880925 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-2-(2-(oxazol-2-yl)propan-2-yl)benzenesulfonamide Show/Hide	C24H20ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0880926 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-(pyrrolidin-1-yl)benzenesulfonamide Show/Hide	C22H20ClN3O3S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0900311 Compound Info	N-[4-Chloro-2-(pyridine-4-carbonyl)-phenyl]-4-thiomorpholin-4-yl-benzenesulfonamide Show/Hide	C22H20ClN3O3S2	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0900312 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-morpholinobenzenesulfonamide Show/Hide	C22H20ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0902229 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-(isopropylthio)benzenesulfonamide Show/Hide	C21H19ClN2O3S2	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0902239 Compound Info	N-[4-cloro-2-(6-methylpyridine-3-carbonyl)-phenyl]-4-(2-methyloxazol-5-yl)-benzenesulfonamide Show/Hide	C23H18ClN3O4S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0903304 Compound Info	4-(azetidin-1-yl)-N-(4-chloro-2-isonicotinoylphenyl)benzenesulfonamide Show/Hide	C21H18ClN3O3S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0911529 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-(1,2,3-thiadiazol-4-yl)benzenesulfonamide Show/Hide	C20H13ClN4O3S2	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0926531 Compound Info	N-(4-chloro-2-(6-methylpicolinoyl)phenyl)-4-(oxazol-5-yl)benzenesulfonamide Show/Hide	C22H16ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0931105 Compound Info	4-Chloro-2-(pyridine-4-carbonyl)-phenyl]-3-([1H]-1-methyltetrazol-3-yl)-benzenesulfonamide Show/Hide	C20H15ClN6O3S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0931106 Compound Info	N-[4-Chloro-2-(pyridine4-carbonyl)-phenyl]-4-(2-fluoropyridin-3-yl)-benzenesulfonamide Show/Hide	C23H15ClFN3O3S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0935584 Compound Info	N-[4-Chloro-2-(pyridine-4-carbonyl)-phenyl]-4-pyrimidin-5-yl-benzenesulfonamide Show/Hide	C22H15ClN4O3S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0935585 Compound Info	N-(4-chloro-2-(piperazine-1-carbonyl)phenyl)-4-methoxybenzenesulfonamide Show/Hide	C18H20ClN3O4S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0949197 Compound Info	N-benzyl-5-chloro-2-(4-methoxyphenylsulfonamido)benzamide Show/Hide	C21H19ClN2O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0949198 Compound Info	5-chloro-2-(4-methoxyphenylsulfonamido)-N-phenylbenzamide Show/Hide	C20H17ClN2O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0951500 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-(piperidin-1-yl)benzenesulfonamide Show/Hide	C23H22ClN3O3S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0951808 Compound Info	4-(5-chloro-2-(4-morpholinophenylsulfonamido)benzoyl)pyridine 1-oxide Show/Hide	C22H20ClN3O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0952104 Compound Info	N-[4-Chloro-2-(1-oxy-pynidime-4-carbonyl)-phenyl]-4-(cis-2,6-dimethyl-morpholin-4-yl)-3-fluorobenzenesulfonamide Show/Hide	C24H23ClFN3O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0952993 Compound Info	N-[4-Chloro-2-(2-methyl-pyridine-3-carbonyl)-phenyl]-4-(4-methyl-tetrahydropyran-4-yl)-benzenesulfonamide Show/Hide	C25H25ClN2O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0952994 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-(furan-3-yl)benzenesulfonamide Show/Hide	C22H15ClN2O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0953508 Compound Info	N-(4-chloro-2-nicotinoylphenyl)-4-(5-methyl-1,3,4-oxadiazol-2-yl)benzenesulfonamide Show/Hide	C21H15ClN4O4S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0954264 Compound Info	3-(5-chloro-2-(4-morpholinophenylsulfonamido)benzoyl)pyridine 1-oxide Show/Hide	C22H20ClN3O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0967241 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-(4-((4R,5R)-2,4,5-trimethyl-1,3-dioxolan-2-yl)piperazin-1-yl)benzenesulfonamide Show/Hide	C28H31ClN4O5S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0849006 Compound Info	N-(4-chloro-2-picolinoylphenyl)-4-(2-(oxazol-5-yl)propan-2-yl)benzenesulfonamide Show/Hide	C24H20ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0849007 Compound Info	N-[4-Chloro-2-(6-methylpyridine-2-carbonyl)-phenyl]-4-(4-methyl-tetrahydropyran-4-yl)-benzenesulfonamide Show/Hide	C25H25ClN2O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0849012 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-iodobenzenesulfonamide Show/Hide	C18H12ClIN2O3S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0850712 Compound Info	N-[4-Chloro-2-(6-methylpyridine-3-carbonyl)-phenyl]-3-fluoro-4-morpholin-4-yl-benzenesulfonamide Show/Hide	C23H21ClFN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0850714 Compound Info	N-[4-Chloro-2-(1-oxy-pyridine-3-carbonyl)-phenyl]-4-(4-methyl-tetrahydropyran-4-yl)-benzenesulfonamide Show/Hide	C24H23ClN2O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0850715 Compound Info	N-[4-Chloro-2-(pyridine-2-carbonyl)-phenyl]-4-(4-methyl-tetrahydropyran-4-yl)-benzenesulfonamide Show/Hide	C24H23ClN2O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0850716 Compound Info	N-(4-chloro-2-(4-methylnicotinoyl)phenyl)-4-(oxazol-5-yl)benzenesulfonamide Show/Hide	C22H16ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0850717 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-(furan-2-yl)benzenesulfonamide Show/Hide	C22H15ClN2O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0850718 Compound Info	N-(4-chloro-2-(2-chloroisonicotinoyl)phenyl)-4-(2-(oxazol-2-yl)propan-2-yl)benzenesulfonamide Show/Hide	C24H19Cl2N3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0850720 Compound Info	3-(5-chloro-2-(4-(2-(oxazol-2-yl)propan-2-yl)phenylsulfonamido)benzoyl)pyridine 1-oxide Show/Hide	C24H20ClN3O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0850721 Compound Info	N-(4,5-difluoro-2-picolinoylphenyl)-4-(2-(oxazol-2-yl)propan-2-yl)benzenesulfonamide Show/Hide	C24H19F2N3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0857804 Compound Info	4-tert-butyl-N-(4-chloro-2-(1-methyl-1H-1,2,3-triazole-5-carbonyl)phenyl)benzenesulfonamide Show/Hide	C20H21ClN4O3S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0857805 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-(2-(oxazol-5-yl)propan-2-yl)benzenesulfonamide Show/Hide	C24H20ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0857806 Compound Info	N-(4-chloro-2-picolinoylphenyl)-4-(5-methyl-1,3,4-oxadiazol-2-yl)benzenesulfonamide Show/Hide	C21H15ClN4O4S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0857807 Compound Info	N-[4-Chloro-2-(pyridine-4-carbonyl)-phenyl]-4-(1H-indol-2-yl)-benzenesulfonamide Show/Hide	C26H18ClN3O3S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0861403 Compound Info	5-(2-(4-acetylphenylsulfonamido)-5-chlorobenzoyl)-2-methylpyridine 1-oxide Show/Hide	C21H17ClN2O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866058 Compound Info	N-(4-chloro-2-nicotinoylphenyl)-4-morpholinobenzenesulfonamide Show/Hide	C22H20ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866059 Compound Info	N-[4-Chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-4-(4-methyltetrahydropyran-4-yl)-benzenesulfonamide Show/Hide	C24H23ClN2O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866060 Compound Info	N-[4-Chloro-2-(6-methylpyridine-3-carbonyl)-phenyl]-4-(cis-2,6-dimethyl-morpholin-4-yl)benzensulfonamide Show/Hide	C25H26ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866061 Compound Info	4-(5-chloro-2-(4-((2S,6R)-2,6-dimethylmorpholino)phenylsulfonamido)benzoyl)pyridine 1-oxide Show/Hide	C24H24ClN3O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866062 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-(2-methyl-1,3-dioxolan-2-yl)benzenesulfonamide Show/Hide	C22H19ClN2O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866081 Compound Info	N-(4-chloro-2-(6-methylpicolinoyl)phenyl)-4-(2-(oxazol-2-yl)propan-2-yl)benzenesulfonamide Show/Hide	C25H22ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866082 Compound Info	5-chloro-2-(4-methoxyphenylsulfonamido)-N-phenethylbenzamide Show/Hide	C22H21ClN2O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866085 Compound Info	4-tert-Butyl-N-[4-chloro-2-(1-methyl-1H-indazole-3-carbonyl)-phenyl]-benzenesulfonamide Show/Hide	C25H24ClN3O3S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0866404 Compound Info	N-[4-Chloro-2-(1-oxy-pyridine-4-carbonyl)phenyl]-4-(1-methyl-1-oxazol-5-ylethyl)-benzenesulfonamide Show/Hide	C24H20ClN3O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0866406 Compound Info	5-(5-chloro-2-(4-morpholinophenylsulfonamido)benzoyl)-2-methylpyridine 1-oxide Show/Hide	C23H22ClN3O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0896511 Compound Info	N-(4-chloro-2-nicotinoylphenyl)-4-(oxazol-2-yl)benzenesulfonamide Show/Hide	C21H14ClN3O4S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0896512 Compound Info	ethyl 2-(5-chloro-2-(4-methoxyphenylsulfonamido)benzamido)acetate Show/Hide	C18H19ClN2O6S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0902232 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-((2S,6R)-2,6-dimethylmorpholino)benzenesulfonamide Show/Hide	C24H24ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0902246 Compound Info	4-chloro-N-(4-chloro-2-isonicotinoylphenyl)benzenesulfonamide Show/Hide	C18H12Cl2N2O3S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0903306 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-(4-methyltetrahydro-2H-pyran-4-yl)benzenesulfonamide Show/Hide	C24H23ClN2O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0903307 Compound Info	N-(4-chloro-2-(6-methylnicotinoyl)phenyl)-4-(trifluoromethoxy)benzenesulfonamide Show/Hide	C20H14ClF3N2O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0903310 Compound Info	N-[4-Chloro-2-(pyridine4-carbonyl)-phenyl]-4-(1H-pyrrol-2-yl)-benzenesulfonamide Show/Hide	C22H16ClN3O3S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0914022 Compound Info	N-[4-Chloro-2(pyridine-4-carbonyl)-phenyl]-4-(1,1-dioxothiomorpholin-4-yl)-benzenesulfonamide Show/Hide	C22H20ClN3O5S2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0914928 Compound Info	2-{4-[4-Chloro-2-(pyridine-4-carbonyl)-phenylsulfamoyl]-phenyl}-indole-1-carboxylic acid tert-Butyl ester Show/Hide	C31H26ClN3O5S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0914929 Compound Info	N-(4-chloro-2-(piperidine-1-carbonyl)phenyl)-4-methoxybenzenesulfonamide Show/Hide	C19H21ClN2O4S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0916668 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-(thiophen-3-yl)benzenesulfonamide Show/Hide	C22H15ClN2O3S2	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0918254 Compound Info	5-(5-chloro-2-(4-((2S,6R)-2,6-dimethylmorpholino)phenylsulfonamido)benzoyl)-2-methylpyridine 1-oxide Show/Hide	C25H26ClN3O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0931108 Compound Info	N-[4-Chloro-2-(6-methylpyridine-3-carbonyl)-phenyl]-4-(cis-2,6-dimethyl-morpholin-4-yl)-3-fluorobenzenesulfonamide Show/Hide	C25H25ClFN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0931109 Compound Info	N-[4-Chloro-2-(pyridine-4-carbonyl)phenyl]-4-(2-oxazol-2-ylethyl)benzenesulfonamide Show/Hide	C23H18ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0931110 Compound Info	N-[4-Chloro-2-(6-methylpyridine-3-carbonyl)-phenyl]-4-(4-methyl-tetrahydropyran-4-yl)-benzenesulfonamide Show/Hide	C25H25ClN2O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0931111 Compound Info	4-tert-Butyl-N-[3,4-difluoro-2-(pyridine-3-carbonyl)-phenyl]benzenesulfonamide Show/Hide	C22H20F2N2O3S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0935576 Compound Info	3-(5-chloro-2-(4-((2S,6R)-2,6-dimethylmorpholino)phenylsulfonamido)benzoyl)pyridine 1-oxide Show/Hide	C24H24ClN3O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0940833 Compound Info	4-(4-acetylpiperazin-1-yl)-N-(4-chloro-2-isonicotinoylphenyl)benzenesulfonamide Show/Hide	C24H23ClN4O4S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0947502 Compound Info	N-[4-Chloro-2-(6-methylpyridine-3-carbonyl)-phenyl]-4-oxazol-5-yl-benzenesulfonamide Show/Hide	C22H16ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0951309 Compound Info	4-tert-butyl-N-(4-chloro-2-(1-methyl-1H-1,2,3-triazole-4-carbonyl)phenyl)benzenesulfonamide Show/Hide	C20H21ClN4O3S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0952467 Compound Info	N-[4-Chloro-2-(6-methyl-1-oxy-pyridine-3-carbonyl)-phenyl]-4-(4-methyl-tetrahydropyran-4-yl)-benzenesulfonamide Show/Hide	C25H25ClN2O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0952468 Compound Info	N-[4-Chloro-2-(pyridine-4-carbonyl)-phenyl]-4-(1-methyl-1-oxazol-2-yl-ethyl)-benzenesulfonamide Show/Hide	C24H20ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0952469 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-(2-(oxazol-2-yl)propan-2-yl)benzenesulfonamide Show/Hide	C24H20ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0952470 Compound Info	4-tert-Butyl-N-4-chloro-2-(1H-pyrazole-3-carbonyl)-phenyl]benzenesulfonamide Show/Hide	C20H20ClN3O3S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0953510 Compound Info	4-(5-chloro-2-(4-(2-methyl-1,3-dioxolan-2-yl)phenylsulfonamido)benzoyl)pyridine 1-oxide Show/Hide	C22H19ClN2O6S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0953978 Compound Info	N-[4-Chloro-2-(pyridine-3-carbonyl)-phenyl]-4-(cis-2,6-dimethyl-morpholine-4-yl]-3-fluorobenzenesulfonamide Show/Hide	C24H24ClN3O4S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0958948 Compound Info	N-(4-chloro-2-(6-methylnicotinoyl)phenyl)-4-(5-methyl-1,3,4-oxadiazol-2-yl)benzenesulfonamide Show/Hide	C22H17ClN4O4S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0960620 Compound Info	N-(4-chloro-2-isonicotinoylphenyl)-4-(4-(2,2,2-trifluoroethyl)piperazin-1-yl)benzenesulfonamide Show/Hide	C24H22ClF3N4O3S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0967540 Compound Info	4-(5-chloro-2-(4-(4-methyl-tetrahydro-2H-pyran-4-yl)phenylsulfonamido)benzoyl)-2-methylpyridine 1-oxide Show/Hide	C25H25ClN2O5S	1
1	IC50 < 1000 nM Bioactivity Info	TI LI LO TS
CP0409626 Compound Info	US9969687, Compound 119 Show/Hide	C24H22ClN3O5S	3
1	Ki = 2 nM Bioactivity Info	TI LI LO TS
2	Ki = 3 nM Bioactivity Info	TI LI LO TS
3	Ki = 35 nM Bioactivity Info	TI LI LO TS
CP0407546 Compound Info	US9969687, Compound 175 Show/Hide	C24H22ClN3O4S	3
1	Ki = 3 nM Bioactivity Info	TI LI LO TS
2	Ki = 12 nM Bioactivity Info	TI LI LO TS
3	Ki = 14 nM Bioactivity Info	TI LI LO TS
CP0409628 Compound Info	US9969687, Compound 183 Show/Hide	C24H22ClN3O5S	2
1	Ki = 3 nM Bioactivity Info	TI LI LO TS
2	Ki = 32 nM Bioactivity Info	TI LI LO TS
CP0456066 Compound Info	US9969687, Compound 194 Show/Hide	C24H22ClN3O6S	3
1	Ki = 4 nM Bioactivity Info	TI LI LO TS
2	Ki = 6 nM Bioactivity Info	TI LI LO TS
3	Ki = 113 nM Bioactivity Info	TI LI LO TS
CP0414634 Compound Info	US9969687, Compound 228 Show/Hide	C24H22ClN3O4S	3
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
2	Ki = 6 nM Bioactivity Info	TI LI LO TS
3	Ki = 19 nM Bioactivity Info	TI LI LO TS
CP0414635 Compound Info	US9969687, Compound 224 Show/Hide	C25H24ClN3O4S	3
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
2	Ki = 6 nM Bioactivity Info	TI LI LO TS
3	Ki > 300 nM Bioactivity Info	TI LI LO TS
CP0409625 Compound Info	US9969687, Compound 222 Show/Hide	C23H20ClN3O4S	3
1	Ki = 6 nM Bioactivity Info	TI LI LO TS
2	Ki = 9 nM Bioactivity Info	TI LI LO TS
3	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0414633 Compound Info	US9969687, Compound 199 Show/Hide	C24H22ClN3O5S	3
1	Ki = 6 nM Bioactivity Info	TI LI LO TS
2	Ki = 10 nM Bioactivity Info	TI LI LO TS
3	Ki = 40 nM Bioactivity Info	TI LI LO TS
CP0420140 Compound Info	US9969687, Compound 176 Show/Hide	C24H22ClN3O5S	3
1	Ki = 6 nM Bioactivity Info	TI LI LO TS
2	Ki = 13 nM Bioactivity Info	TI LI LO TS
3	Ki = 24 nM Bioactivity Info	TI LI LO TS
CP0567146 Compound Info	US9969687, Compound 244 Show/Hide	C24H22ClN3O4S	1
1	Ki = 6 nM Bioactivity Info	TI LI LO TS
CP0409627 Compound Info	US9969687, Compound 218 Show/Hide	C23H19ClFN3O4S	3
1	Ki = 7 nM Bioactivity Info	TI LI LO TS
2	Ki = 26 nM Bioactivity Info	TI LI LO TS
3	Ki = 91 nM Bioactivity Info	TI LI LO TS
CP0570916 Compound Info	US9969687, Compound 185 Show/Hide	C24H22ClN3O4S	1
1	Ki = 7 nM Bioactivity Info	TI LI LO TS
CP0414564 Compound Info	US9969687, Compound 230 Show/Hide	C25H24ClN3O6S	1
1	Ki = 8 nM Bioactivity Info	TI LI LO TS
CP0414632 Compound Info	US9969687, Compound 201 Show/Hide	C24H22ClN3O4S	3
1	Ki = 8 nM Bioactivity Info	TI LI LO TS
2	Ki = 17 nM Bioactivity Info	TI LI LO TS
3	Ki > 100 nM Bioactivity Info	TI LI LO TS
CP0573776 Compound Info	US9969687, Compound 271 Show/Hide	C25H24ClN3O5S	1
1	Ki = 9 nM Bioactivity Info	TI LI LO TS
CP0499797 Compound Info	US9969687, Compound 219 Show/Hide	C23H19ClFN3O4S	1
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0499796 Compound Info	US9969687, Compound 264 Show/Hide	C23H20ClN3O4S	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0534603 Compound Info	US9969687, Compound 263 Show/Hide	C25H24ClN3O4S	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0399124 Compound Info	US9969687, Compound 213 Show/Hide	C25H24ClN3O5S	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0420259 Compound Info	US9969687, Compound 65 Show/Hide	C24H22ClN3O5S	3
1	Ki = 13 nM Bioactivity Info	TI LI LO TS
2	Ki = 38 nM Bioactivity Info	TI LI LO TS
3	Ki = 74 nM Bioactivity Info	TI LI LO TS
CP0553209 Compound Info	US9969687, Compound 239 Show/Hide	C24H21ClFN3O4S	1
1	Ki = 13 nM Bioactivity Info	TI LI LO TS
CP0553210 Compound Info	US9969687, Compound 259 Show/Hide	C25H24ClN3O5S	1
1	Ki = 13 nM Bioactivity Info	TI LI LO TS
CP0534601 Compound Info	US9969687, Compound 238 Show/Hide	C25H24ClN3O5S	1
1	Ki = 14 nM Bioactivity Info	TI LI LO TS
CP0399275 Compound Info	US9969687, Compound 44 Show/Hide	C23H20ClN3O5S	1
1	Ki = 16 nM Bioactivity Info	TI LI LO TS
CP0534602 Compound Info	US9969687, Compound 261 Show/Hide	C25H24ClN3O5S	1
1	Ki = 16 nM Bioactivity Info	TI LI LO TS
CP0573773 Compound Info	US9969687, Compound 260 Show/Hide	C25H24ClN3O5S	1
1	Ki = 16 nM Bioactivity Info	TI LI LO TS
CP0534599 Compound Info	US9969687, Compound 242 Show/Hide	C25H24ClN3O5S	1
1	Ki = 18 nM Bioactivity Info	TI LI LO TS
CP0573775 Compound Info	US9969687, Compound 256 Show/Hide	C25H21ClN4O4S	1
1	Ki = 18 nM Bioactivity Info	TI LI LO TS
CP0419965 Compound Info	US9969687, Compound 182 Show/Hide	C24H22ClN3O4S	1
1	Ki = 19 nM Bioactivity Info	TI LI LO TS
CP0534604 Compound Info	US9969687, Compound 82 Show/Hide	C25H22N4O4S	1
1	Ki = 19 nM Bioactivity Info	TI LI LO TS
CP0570917 Compound Info	4-tert-butyl-N-[7-chloro-2-(6-fluoropyridin-3-yl)-1,3-dioxoisoindol-4-yl]benzenesulfonamide Show/Hide	C23H19ClFN3O4S	1
1	Ki = 19 nM Bioactivity Info	TI LI LO TS
CP0386115 Compound Info	US9969687, Compound 191 Show/Hide	C24H22ClN3O4S	1
1	Ki = 20 nM Bioactivity Info	TI LI LO TS
CP0568655 Compound Info	US9969687, Compound 226 Show/Hide	C24H22ClN3O4S	1
1	Ki = 21 nM Bioactivity Info	TI LI LO TS
CP0409678 Compound Info	US9969687, Compound 276 Show/Hide	C23H19ClFN3O4S	1
1	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0420141 Compound Info	US9969687, Compound 64 Show/Hide	C24H22ClN3O4S	3
1	Ki = 22 nM Bioactivity Info	TI LI LO TS
2	Ki = 27 nM Bioactivity Info	TI LI LO TS
3	Ki = 357 nM Bioactivity Info	TI LI LO TS
CP0420258 Compound Info	US9969687, Compound 202 Show/Hide	C24H22ClN3O5S	1
1	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0499799 Compound Info	US9969687, Compound 90 Show/Hide	C24H22ClN3O5S	1
1	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0556968 Compound Info	US9969687, Compound 258 Show/Hide	C25H24ClN3O4S	1
1	Ki = 23 nM Bioactivity Info	TI LI LO TS
CP0390669 Compound Info	US9969687, Compound 208 Show/Hide	C25H24ClN3O4S	1
1	Ki = 24 nM Bioactivity Info	TI LI LO TS
CP0534598 Compound Info	US9969687, Compound 257 Show/Hide	C26H26ClN3O5S	1
1	Ki = 25 nM Bioactivity Info	TI LI LO TS
CP0570918 Compound Info	US9969687, Compound 43 Show/Hide	C23H20ClN3O4S	1
1	Ki = 25 nM Bioactivity Info	TI LI LO TS
CP0534600 Compound Info	US9969687, Compound 237 Show/Hide	C25H24ClN3O5S	1
1	Ki = 28 nM Bioactivity Info	TI LI LO TS
CP0483486 Compound Info	US9969687, Compound 104 Show/Hide	C24H22ClN3O4S	1
1	Ki = 30 nM Bioactivity Info	TI LI LO TS
CP0573774 Compound Info	US9969687, Compound 207 Show/Hide	C24H19ClN4O4S	1
1	Ki = 30 nM Bioactivity Info	TI LI LO TS
CP0574413 Compound Info	US9969687, Compound 209 Show/Hide	C24H22ClN3O5S	1
1	Ki = 30 nM Bioactivity Info	TI LI LO TS
CP0534551 Compound Info	US9969687, Compound 195 Show/Hide	C25H21ClN4O4S	1
1	Ki = 31 nM Bioactivity Info	TI LI LO TS
CP0474134 Compound Info	US9969687, Compound 200 Show/Hide	C24H19ClN4O4S	1
1	Ki = 45 nM Bioactivity Info	TI LI LO TS
CP0553211 Compound Info	US9969687, Compound 251 Show/Hide	C25H24ClN3O4S	1
1	Ki = 51 nM Bioactivity Info	TI LI LO TS
CP0419964 Compound Info	US9969687, Compound 225 Show/Hide	C24H22ClN3O4S	1
1	Ki = 54 nM Bioactivity Info	TI LI LO TS
CP0556969 Compound Info	US9969687, Compound 254 Show/Hide	C25H24ClN3O4S	1
1	Ki = 58 nM Bioactivity Info	TI LI LO TS
CP0557990 Compound Info	US9969687, Compound 212 Show/Hide	C25H24ClN3O5S	1
1	Ki = 59 nM Bioactivity Info	TI LI LO TS
CP0469648 Compound Info	4-tert-butyl-N-[7-chloro-2-(5-cyanopyridin-3-yl)-1,3-dioxoisoindol-4-yl]benzenesulfonamide Show/Hide	C24H19ClN4O4S	1
1	Ki = 73 nM Bioactivity Info	TI LI LO TS
CP0399123 Compound Info	US9969687, Compound 247 Show/Hide	C25H24ClN3O5S	1
1	Ki = 78 nM Bioactivity Info	TI LI LO TS
CP0499798 Compound Info	4-tert-butyl-N-[7-chloro-2-(6-methoxypyridin-3-yl)-1,3-dioxoisoindol-4-yl]benzenesulfonamide Show/Hide	C24H22ClN3O5S	1
1	Ki = 78 nM Bioactivity Info	TI LI LO TS
CP0434645 Compound Info	4-tert-butyl-N-[7-chloro-2-[(6-methylpyridin-3-yl)methyl]-1,3-dioxoisoindol-4-yl]benzenesulfonamide Show/Hide	C25H24ClN3O4S	1
1	Ki = 85 nM Bioactivity Info	TI LI LO TS
CP0573777 Compound Info	4-tert-butyl-N-[7-chloro-1,3-dioxo-2-(2-pyridin-3-ylethyl)isoindol-4-yl]benzenesulfonamide Show/Hide	C25H24ClN3O4S	1
1	Ki = 100 nM Bioactivity Info	TI LI LO TS
CP0483544 Compound Info	4-tert-butyl-N-[7-chloro-2-[(2-methoxypyridin-4-yl)methyl]-1,3-dioxoisoindol-4-yl]benzenesulfonamide Show/Hide	C25H24ClN3O5S	1
1	Ki = 108 nM Bioactivity Info	TI LI LO TS
CP0542107 Compound Info	N-(1,3-dioxo-2-pyridin-3-ylisoindol-4-yl)-4-(trifluoromethoxy)benzenesulfonamide Show/Hide	C20H12F3N3O5S	1
1	Ki = 123 nM Bioactivity Info	TI LI LO TS
CP0557989 Compound Info	US9969687, Compound 235 Show/Hide	C25H24ClN3O5S	1
1	Ki = 123 nM Bioactivity Info	TI LI LO TS
CP0409679 Compound Info	US9969687, Compound 103 Show/Hide	C25H24ClN3O5S	1
1	Ki = 128 nM Bioactivity Info	TI LI LO TS
CP0490505 Compound Info	4-tert-butyl-N-(7-methyl-1,3-dioxo-2-pyridin-3-ylisoindol-4-yl)benzenesulfonamide Show/Hide	C24H23N3O4S	1
1	Ki = 189 nM Bioactivity Info	TI LI LO TS
CP0570920 Compound Info	4-chloro-N-(1,3-dioxo-2-pyridin-3-ylisoindol-4-yl)-3-(trifluoromethyl)benzenesulfonamide Show/Hide	C20H11ClF3N3O4S	1
1	Ki = 206 nM Bioactivity Info	TI LI LO TS
CP0419966 Compound Info	US9969687, Compound 160 Show/Hide	C25H25N3O4S	1
1	Ki = 456 nM Bioactivity Info	TI LI LO TS
CP0459695 Compound Info	US9969687, Compound 1 Show/Hide	C23H21N3O4S	1
1	Ki = 479 nM Bioactivity Info	TI LI LO TS
CP0570919 Compound Info	4-tert-butyl-N-[1,3-dioxo-2-(pyridin-3-ylmethyl)isoindol-4-yl]benzenesulfonamide Show/Hide	C24H23N3O4S	1
1	Ki = 618 nM Bioactivity Info	TI LI LO TS
CP0399276 Compound Info	N-(1,3-dioxo-2-pyridin-3-ylisoindol-4-yl)-4-fluoro-3-(trifluoromethyl)benzenesulfonamide Show/Hide	C20H11F4N3O4S	1
1	Ki = 1322 nM Bioactivity Info	TI LI LO TS
CP0499800 Compound Info	N-(1,3-dioxo-2-pyridin-3-ylisoindol-4-yl)-3-(trifluoromethyl)benzenesulfonamide Show/Hide	C20H12F3N3O4S	1
1	Ki = 2713 nM Bioactivity Info	TI LI LO TS

Biochemical Assays

Compound ID	Compound Name	Compound Formula
CP0133635 Compound Info	1-[(4-tert-butylphenyl)methyl]-6-chloropyrrolo[3,2-c]pyridine-2-carboxylic acid Show/Hide	C19H19ClN2O2	1
1	IC50 = 1.5 nM
CP0109129 Compound Info	4-tert-butyl-N-[4-chloro-2-(1-oxidopyridin-1-ium-4-carbonyl)phenyl]benzenesulfonamide Show/Hide	C22H21ClN2O4S	5
1	IC50 = 5 nM
2	IC50 = 6 nM
3	IC50 = 10 nM
4	IC50 = 11 nM
5	IC50 = 539 nM
CP0190640 Compound Info	1-[(4-tert-butylphenyl)methyl]-6-chloropyrrolo[3,2-b]pyridine-2-carboxylic acid Show/Hide	C19H19ClN2O2	1
1	IC50 = 20 nM
CP0240491 Compound Info	6-chloro-1-[[4-(1-methoxy-2-methylpropan-2-yl)phenyl]methyl]pyrrolo[3,2-b]pyridine-2-carboxylic acid Show/Hide	C20H21ClN2O3	1
1	IC50 = 35 nM
CP0190641 Compound Info	6-chloro-1-[[4-(4-methyloxan-4-yl)phenyl]methyl]pyrrolo[3,2-b]pyridine-2-carboxylic acid Show/Hide	C21H21ClN2O3	1
1	IC50 = 70 nM
CP0068011 Compound Info	6-chloro-1-[[4-(trifluoromethyl)phenyl]methyl]pyrrolo[3,2-b]pyridine-2-carboxylic acid Show/Hide	C16H10ClF3N2O2	1
1	IC50 = 113 nM
CP0190639 Compound Info	1-[(4-tert-butylphenyl)methyl]-6-chloroindole-2-carboxylic acid Show/Hide	C20H20ClNO2	1
1	IC50 = 232 nM
CP0329147 Compound Info	1-[(4-tert-butylphenyl)methyl]-5-chloropyrrolo[2,3-c]pyridine-2-carboxylic acid Show/Hide	C19H19ClN2O2	1
1	IC50 = 378 nM

Clinical Information about the Protein

Target 1 ( C-C chemokine receptor type 9 (CCR9) )

Target Type	Clinical trial Target
Disease	1 Target-related Disease				1
1	Crohn disease [ICD-11: DD70]
Clinical Trial Drug(s)	1 Clinical Trial Drug				1
1	Vercirnon	Drug Info	Phase 3	Crohn disease

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han