General Information of the Compound
Compound ID
CP0931108
Compound Name
N-[4-Chloro-2-(6-methylpyridine-3-carbonyl)-phenyl]-4-(cis-2,6-dimethyl-morpholin-4-yl)-3-fluorobenzenesulfonamide
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Structure
Formula
C25H25ClFN3O4S
Molecular Weight
518.01
Canonical SMILES
Cc1ccc(C(=O)c2cc(Cl)ccc2NS(=O)(=O)c2ccc(N3C[C@@H](C)O[C@@H](C)C3)c(F)c2)cn1
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InChI
InChI=1S/C25H25ClFN3O4S/c1-15-4-5-18(12-28-15)25(31)21-10-19(26)6-8-23(21)29-35(32,33)20-7-9-24(22(27)11-20)30-13-16(2)34-17(3)14-30/h4-12,16-17,29H,13-14H2,1-3H3/t16-,17+
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InChIKey
VOCNRPSKUVPJCF-CALCHBBNSA-N
Physicochemical Property
logP
4.82792
Rotatable Bonds
6
Heavy Atom Count
35
Polar Areas
88.6
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 59788542
ChEMBL ID
CHEMBL3717697
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03549, C-C chemokine receptor type 9
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000116 MOLT-4 Homo sapiens (Human)  1
1
IC50 < 1000 nM
   TI
   LI
   LO
   TS