General Information of the Compound
Compound ID
CP0914928
Compound Name
2-{4-[4-Chloro-2-(pyridine-4-carbonyl)-phenylsulfamoyl]-phenyl}-indole-1-carboxylic acid tert-Butyl ester
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Structure
Formula
C31H26ClN3O5S
Molecular Weight
588.085
Canonical SMILES
CC(C)(C)OC(=O)n1c(-c2ccc(S(=O)(=O)Nc3ccc(Cl)cc3C(=O)c3ccncc3)cc2)cc2ccccc21
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InChI
InChI=1S/C31H26ClN3O5S/c1-31(2,3)40-30(37)35-27-7-5-4-6-22(27)18-28(35)20-8-11-24(12-9-20)41(38,39)34-26-13-10-23(32)19-25(26)29(36)21-14-16-33-17-15-21/h4-19,34H,1-3H3
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InChIKey
UTPDYJUBTDFAOK-UHFFFAOYSA-N
Physicochemical Property
logP
7.1717
Rotatable Bonds
6
Heavy Atom Count
41
Polar Areas
107.36
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
41

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 59788590
ChEMBL ID
CHEMBL3719171
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03549, C-C chemokine receptor type 9
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000116 MOLT-4 Homo sapiens (Human)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS