General Information of the Compound
Compound ID
CP0848995
Compound Name
N-(2-(3-benzylpiperidine-1-carbonyl)-4-chlorophenyl)-4-methoxybenzenesulfonamide
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Structure
Formula
C26H27ClN2O4S
Molecular Weight
499.032
Canonical SMILES
COc1ccc(S(=O)(=O)Nc2ccc(Cl)cc2C(=O)N2CCCC(Cc3ccccc3)C2)cc1
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InChI
InChI=1S/C26H27ClN2O4S/c1-33-22-10-12-23(13-11-22)34(31,32)28-25-14-9-21(27)17-24(25)26(30)29-15-5-8-20(18-29)16-19-6-3-2-4-7-19/h2-4,6-7,9-14,17,20,28H,5,8,15-16,18H2,1H3
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InChIKey
UYZRPGALSJWDEL-UHFFFAOYSA-N
Physicochemical Property
logP
5.2443
Rotatable Bonds
7
Heavy Atom Count
34
Polar Areas
75.71
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 59788619
ChEMBL ID
CHEMBL3715892
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03549, C-C chemokine receptor type 9
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000116 MOLT-4 Homo sapiens (Human)  1
1
IC50 > 1000 nM
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