General Information of the Compound
Compound ID
CP0952104
Compound Name
N-[4-Chloro-2-(1-oxy-pynidime-4-carbonyl)-phenyl]-4-(cis-2,6-dimethyl-morpholin-4-yl)-3-fluorobenzenesulfonamide
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Structure
Formula
C24H23ClFN3O5S
Molecular Weight
519.982
Canonical SMILES
C[C@@H]1CN(c2ccc(S(=O)(=O)Nc3ccc(Cl)cc3C(=O)c3cc[n+]([O-])cc3)cc2F)C[C@H](C)O1
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InChI
InChI=1S/C24H23ClFN3O5S/c1-15-13-28(14-16(2)34-15)23-6-4-19(12-21(23)26)35(32,33)27-22-5-3-18(25)11-20(22)24(30)17-7-9-29(31)10-8-17/h3-12,15-16,27H,13-14H2,1-2H3/t15-,16+
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InChIKey
DIJHIJMLWZYVAL-IYBDPMFKSA-N
Physicochemical Property
logP
3.7579
Rotatable Bonds
6
Heavy Atom Count
35
Polar Areas
102.65
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 59788538
ChEMBL ID
CHEMBL3715317
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03549, C-C chemokine receptor type 9
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000116 MOLT-4 Homo sapiens (Human)  1
1
IC50 < 1000 nM
   TI
   LI
   LO
   TS