General Information of the Compound
Compound ID
CP0914930
Compound Name
2-(4-(N-(4-chloro-2-(pyridine-4-carbonyl)phenyl)sulfamoyl)phenyl)-N,N,2-trimethylpropanamide
    Show/Hide
Structure
Formula
C24H24ClN3O4S
Molecular Weight
485.993
Canonical SMILES
CN(C)C(=O)C(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2C(=O)c2ccncc2)cc1
    Show/Hide
InChI
InChI=1S/C24H24ClN3O4S/c1-24(2,23(30)28(3)4)17-5-8-19(9-6-17)33(31,32)27-21-10-7-18(25)15-20(21)22(29)16-11-13-26-14-12-16/h5-15,27H,1-4H3
    Show/Hide
InChIKey
DORQWLQRKMCLIB-UHFFFAOYSA-N
Physicochemical Property
logP
4.1326
Rotatable Bonds
7
Heavy Atom Count
33
Polar Areas
96.44
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 20827654
ChEMBL ID
CHEMBL3718191
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03549, C-C chemokine receptor type 9
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000116 MOLT-4 Homo sapiens (Human)  2
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
2
IC50 > 1000 nM
   TI
   LI
   LO
   TS