General Information of the Compound
Compound ID
CP0967241
Compound Name
N-(4-chloro-2-isonicotinoylphenyl)-4-(4-((4R,5R)-2,4,5-trimethyl-1,3-dioxolan-2-yl)piperazin-1-yl)benzenesulfonamide
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Structure
Formula
C28H31ClN4O5S
Molecular Weight
571.099
Canonical SMILES
C[C@H]1OC(C)(N2CCN(c3ccc(S(=O)(=O)Nc4ccc(Cl)cc4C(=O)c4ccncc4)cc3)CC2)O[C@@H]1C
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InChI
InChI=1S/C28H31ClN4O5S/c1-19-20(2)38-28(3,37-19)33-16-14-32(15-17-33)23-5-7-24(8-6-23)39(35,36)31-26-9-4-22(29)18-25(26)27(34)21-10-12-30-13-11-21/h4-13,18-20,31H,14-17H2,1-3H3/t19-,20-/m1/s1
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InChIKey
JAIIDNMTTHBYDA-WOJBJXKFSA-N
Physicochemical Property
logP
4.3863
Rotatable Bonds
7
Heavy Atom Count
39
Polar Areas
101.07
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
8
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 127024543
ChEMBL ID
CHEMBL3718094
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03549, C-C chemokine receptor type 9
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000116 MOLT-4 Homo sapiens (Human)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS