General Information of the Protein
Protein ID
PT01561
Protein Name
Glycogen phosphorylase, liver form
Gene Name
PYGL
Sequence
MAKPLTDQEKRRQISIRGIVGVENVAELKKSFNRHLHFTLVKDRNVATTRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQLGLDIEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIRDGWQVEEADDWLRYGNPWEKSRPEFMLPVHFYGKVEHTNTGTKWIDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLRDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKASKFGSTRGAGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWELTQKTFAYTNHTVLPEALERWPVDLVEKLLPRHLEIIYEINQKHLDRIVALFPKDVDRLRRMSLIEEEGSKRINMAHLCIVGSHAVNGVAKIHSDIVKTKVFKDFSELEPDKFQNKTNGITPRRWLLLCNPGLAELIAEKIGEDYVKDLSQLTKLHSFLGDDVFLRELAKVKQENKLKFSQFLETEYKVKINPSSMFDVQVKRIHEYKRQLLNCLHVITMYNRIKKDPKKLFVPRTVIIGGKAAPGYHMAKMIIKLITSVADVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRIDDVAALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPKQPDLFKDIINMLFYHDRFKVFADYEAYVKCQDKVSQLYMNPKAWNTMVLKNIAASGKFSSDRTIKEYAQNIWNVEPSDLKISLSNESNKVNGN
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Organism
Homo sapiens, Human
Protein Classification
Enzyme
Function
Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
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Uniprot ID
Primary ID:
P06737

Secondarily ID:
A6NDQ4
B4DUB7
F5H816
O60567
O60752
O60913
Q501V9
Q641R5
Q96G82
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Ensembl ID
ENSG00000100504
HGNC ID
HGNC:9725
Subcellular Location
Cytoplasm
Cytosol
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000063 , Hep-G2
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0521342
 Compound Info 
(2S,3R)-3-(tert-butoxy)-2-{[4-(4-methoxyphenyl)-2-{[(2,4,6-trimethylphenyl)carbamoyl]amino}phenyl]formamido}butanoic acid
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C32H39N3O6
  1
1
IC50 = 34 nM
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CP0452531
 Compound Info 
(2S,3R)-3-(tert-butoxy)-2-{[4-(4-fluorophenyl)-2-{[(2,4,6-trimethylphenyl)carbamoyl]amino}phenyl]formamido}butanoic acid
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C31H36FN3O5
  1
1
IC50 = 88 nM
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CP0491351
 Compound Info 
(2S,3R)-3-(tert-butoxy)-2-{[4-(3-fluorophenyl)-2-{[(2,4,6-trimethylphenyl)carbamoyl]amino}phenyl]formamido}butanoic acid
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C31H36FN3O5
  1
1
IC50 = 104 nM
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CP0549458
 Compound Info 
(2S,3R)-3-(tert-butoxy)-2-{[4-(3-methoxyphenyl)-2-{[(2,4,6-trimethylphenyl)carbamoyl]amino}phenyl]formamido}butanoic acid
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C32H39N3O6
  1
1
IC50 = 109 nM
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CP0439570
 Compound Info 
(2S,3R)-3-(tert-butoxy)-2-[(4-phenyl-2-{[(2,4,6-trimethylphenyl)carbamoyl]amino}phenyl)formamido]butanoic acid
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C31H37N3O5
  1
1
IC50 = 126 nM
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CP0498892
 Compound Info 
(2S,3R)-3-(tert-butoxy)-2-{[2-({[4-(cyclopropylmethyl)-2,6-dimethylphenyl]carbamoyl}amino)-4-fluorophenyl]formamido}butanoic acid
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C28H36FN3O5
  1
1
IC50 = 133 nM
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CP0452534
 Compound Info 
(2S,3R)-3-(tert-butoxy)-2-[(2-{[(2,6-dimethyl-4-propylphenyl)carbamoyl]amino}-4-(4-methoxyphenyl)phenyl)formamido]butanoic acid
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C34H43N3O6
  1
1
IC50 = 135 nM
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CP0238098
 Compound Info 
(2S,3R)-3-(tert-butoxy)-2-[(3-{[(2,4,6-trimethylphenyl)carbamoyl]amino}naphthalen-2-yl)formamido]butanoic acid
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C29H35N3O5
  1
1
IC50 = 139 nM
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CP0498893
 Compound Info 
(2S,3R)-3-(tert-butoxy)-2-{[2-({[4-(cyclopropylmethyl)-2,6-dimethylphenyl]carbamoyl}amino)-4-(3-fluorophenyl)phenyl]formamido}butanoic acid
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C34H40FN3O5
  1
1
IC50 = 145 nM
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CP0517523
 Compound Info 
(2S,3R)-3-(tert-butoxy)-2-[(2-{[(2,6-dimethyl-4-propylphenyl)carbamoyl]amino}-4-fluorophenyl)formamido]butanoic acid
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C27H36FN3O5
  1
1
IC50 = 147 nM
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CP0434853
 Compound Info 
(2S,3R)-3-(tert-butoxy)-2-[(2-{[(2,6-dimethyl-4-propylphenyl)carbamoyl]amino}-4-(3-fluorophenyl)phenyl)formamido]butanoic acid
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C33H40FN3O5
  1
1
IC50 = 156 nM
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CP0317042
 Compound Info 
(2S,3R)-3-isopropoxy-2-(3-(3-mesitylureido)-2-naphthamido)butanoic acid
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C28H33N3O5
  1
1
IC50 = 156 nM
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CP0285686
 Compound Info 
(2S,3R)-2-(3-(3-mesitylureido)-2-naphthamido)-3-(1-methylcyclopentyloxy)butanoic acid
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C31H37N3O5
  1
1
IC50 = 159 nM
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CP0521343
 Compound Info 
(2S,3R)-3-(tert-butoxy)-2-{[4-(3,4-difluorophenyl)-2-{[(2,4,6-trimethylphenyl)carbamoyl]amino}phenyl]formamido}butanoic acid
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C31H35F2N3O5
  1
1
IC50 = 171 nM
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CP0401326
 Compound Info 
(2S,3R)-3-(tert-butoxy)-2-{[4-(3,4-difluorophenyl)-2-{[(2,6-dimethyl-4-propylphenyl)carbamoyl]amino}phenyl]formamido}butanoic acid
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C33H39F2N3O5
  1
1
IC50 = 181 nM
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CP0441399
 Compound Info 
(S)-2-cyclohexyl-2-(3-(3-(2,4,6-trichlorophenyl)ureido)-2-naphthamido)acetic acid
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C26H24Cl3N3O4
  1
1
IC50 = 224 nM
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CP0498891
 Compound Info 
(2S)-2-cyclohexyl-2-[(2-{[(2,6-dimethyl-4-propylphenyl)carbamoyl]amino}-4-fluorophenyl)formamido]acetic acid
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C27H34FN3O4
  1
1
IC50 = 229 nM
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CP0418990
 Compound Info 
(S)-2-cyclohexyl-2-(3-(3-(2,6-dichloro-4-(trifluoromethoxy)phenyl)ureido)-2-naphthamido)acetic acid
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C27H24Cl2F3N3O5
  1
1
IC50 = 273 nM
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CP0237998
 Compound Info 
(2S,3R)-3-(benzyloxy)-2-(3-(3-mesitylureido)-2-naphthamido)pentanoic acid
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C33H35N3O5
  1
1
IC50 = 309 nM
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CP0349093
 Compound Info 
(S)-2-(3-(3-mesitylureido)-2-naphthamido)-5,5-dimethylhexanoic acid
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C29H35N3O4
  1
1
IC50 = 311 nM
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CP0245087
 Compound Info 
(S)-2-cyclohexyl-2-(2-(3-(2,6-dichlorophenyl)ureido)-2-naphthamido)acetic acid
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C26H25Cl2N3O4
  1
1
IC50 = 320 nM
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CP0333043
 Compound Info 
(S)-2-cyclopentyl-2-(3-(3-mesitylureido)-2-naphthamido)acetic acid
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C28H31N3O4
  1
1
IC50 = 321 nM
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CP0091053
 Compound Info 
(S)-2-cyclohexyl-2-(3-(3-mesitylureido)-2-naphthamido)propanoic acid
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C30H35N3O4
  1
1
IC50 = 350 nM
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CP0452530
 Compound Info 
(2S,3R)-3-(tert-butoxy)-2-{[4-(2-methoxyphenyl)-2-{[(2,4,6-trimethylphenyl)carbamoyl]amino}phenyl]formamido}butanoic acid
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C32H39N3O6
  1
1
IC50 = 353 nM
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CP0237992
 Compound Info 
(S)-2-cyclohexyl-2-(3-(3-mesitylureido)-2-naphthamido)acetic acid
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C29H33N3O4
  1
1
IC50 = 373 nM
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CP0452533
 Compound Info 
(2S)-2-cyclohexyl-2-{[2-({[4-(cyclopropylmethyl)-2,6-dimethylphenyl]carbamoyl}amino)-4-fluorophenyl]formamido}acetic acid
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C28H34FN3O4
  1
1
IC50 = 384 nM
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CP0317039
 Compound Info 
(S)-3-tert-butoxy-2-(3-(3-mesitylureido)-2-naphthamido)propanoic acid
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C28H33N3O5
  1
1
IC50 = 387 nM
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CP0235352
 Compound Info 
(2S,3R)-3-(benzyloxy)-2-(3-(3-mesitylureido)-2-naphthamido)butanoic acid
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C32H33N3O5
  1
1
IC50 = 420 nM
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CP0235353
 Compound Info 
(2S,3R)-3-cyclobutoxy-2-(3-(3-mesitylureido)-2-naphthamido)butanoic acid
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C29H33N3O5
  1
1
IC50 = 434 nM
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CP0333044
 Compound Info 
1-(3-(3-mesitylureido)-2-naphthamido)cyclodecanecarboxylic acid
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C32H39N3O4
  1
1
IC50 = 443 nM
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CP0313070
 Compound Info 
(S)-3-isopropoxy-2-(3-(3-mesitylureido)-2-naphthamido)propanoic acid
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C27H31N3O5
  1
1
IC50 = 451 nM
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CP0317037
 Compound Info 
(S)-2-(3-(3-mesitylureido)-2-naphthamido)-5-methylhexanoic acid
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C28H33N3O4
  1
1
IC50 = 452 nM
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CP0237996
 Compound Info 
1-(3-(3-mesitylureido)-2-naphthamido)cyclooctanecarboxylic acid
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C30H35N3O4
  1
1
IC50 = 498 nM
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CP0330938
 Compound Info 
(S)-2-(3-(3-mesitylureido)-2-naphthamido)hexanoic acid
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C27H31N3O4
  1
1
IC50 = 501 nM
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CP0401325
 Compound Info 
(2S)-2-cyclohexyl-2-[(2-{[(4-ethyl-2,6-dimethylphenyl)carbamoyl]amino}-4-fluorophenyl)formamido]acetic acid
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C26H32FN3O4
  1
1
IC50 = 513 nM
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CP0091057
 Compound Info 
1-(3-(3-mesitylureido)-2-naphthamido)cycloheptanecarboxylic acid
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C29H33N3O4
  1
1
IC50 = 585 nM
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CP0037355
 Compound Info 
(2S)-2-[(3-{[(2-chloro-6-methylphenyl)carbamoyl]amino}naphthalen-2-yl)formamido]-2-cyclohexylacetic acid
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C27H28ClN3O4
  2
1
IC50 = 600 nM
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2
IC50 = 1290 nM
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CP0237997
 Compound Info 
(2S,3R)-3-(benzyloxy)-2-(3-(3-mesitylureido)-2-naphthamido)-5-methylhexanoic acid
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C35H39N3O5
  1
1
IC50 = 613 nM
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CP0341353
 Compound Info 
(S)-2-(2-(3-(2,6-dichlorophenyl)ureido)-2-naphthamido)succinic acid
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C22H17Cl2N3O6
  1
1
IC50 = 640 nM
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CP0317038
 Compound Info 
(2S,3S)-2-(3-(3-mesitylureido)-2-naphthamido)-3-methylpentanoic acid
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C27H31N3O4
  1
1
IC50 = 688 nM
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CP0548962
 Compound Info 
(2S)-2-[(2-{[(4-butyl-2,6-dimethylphenyl)carbamoyl]amino}-4-fluorophenyl)formamido]-2-cyclohexylacetic acid
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C28H36FN3O4
  1
1
IC50 = 716 nM
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CP0330933
 Compound Info 
(S)-2-((1r,4S)-4-methylcyclohexyl)-2-(3-(3-(2,4,6-trichlorophenyl)ureido)-2-naphthamido)acetic acid
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C27H26Cl3N3O4
  1
1
IC50 = 845 nM
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CP0237999
 Compound Info 
(S)-2-(3-(3-mesitylureido)-2-naphthamido)-3-(neopentyloxy)propanoic acid
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C29H35N3O5
  1
1
IC50 = 949 nM
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CP0237993
 Compound Info 
2-(4,4-difluorocyclohexyl)-2-(3-(3-mesitylureido)-2-naphthamido)acetic acid
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C29H31F2N3O4
  1
1
IC50 = 1005 nM
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CP0317040
 Compound Info 
(S)-2-(3-(3-mesitylureido)-2-naphthamido)pentanoic acid
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C26H29N3O4
  1
1
IC50 = 1019 nM
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CP0439571
 Compound Info 
(2S)-2-cyclohexyl-2-[(4-fluoro-2-{[(2,4,6-trimethylphenyl)carbamoyl]amino}phenyl)formamido]acetic acid
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C25H30FN3O4
  1
1
IC50 = 1026 nM
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CP0245086
 Compound Info 
(S)-2-cyclohexyl-2-(2-(3-(2,6-dimethylphenyl)ureido)-2-naphthamido)acetic acid
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C28H31N3O4
  2
1
IC50 = 1060 nM
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2
IC50 = 1100 nM
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CP0279539
 Compound Info 
2-(3-(3-mesitylureido)-2-naphthamido)-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid
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C32H31N3O4
  1
1
IC50 = 1070 nM
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CP0128788
 Compound Info 
(S)-2-(2-(3-(2,6-dimethylphenyl)ureido)-2-naphthamido)succinic acid
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C24H23N3O6
  1
1
IC50 = 1100 nM
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CP0333756
 Compound Info 
(2S,3S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)-3-methylpentanoic acid
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C25H26ClN3O4
  1
1
IC50 = 1100 nM
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CP0313079
 Compound Info 
(S)-2-(3-(3-mesitylureido)-2-naphthamido)-3,3-dimethylbutanoic acid
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C27H31N3O4
  1
1
IC50 = 1138 nM
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CP0313080
 Compound Info 
(S)-3-butoxy-2-(3-(3-mesitylureido)-2-naphthamido)propanoic acid
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C28H33N3O5
  1
1
IC50 = 1139 nM
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CP0279542
 Compound Info 
(S)-2-(3-(3-mesitylureido)-2-naphthamido)-3-methylbutanoic acid
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C26H29N3O4
  1
1
IC50 = 1170 nM
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CP0317036
 Compound Info 
1-(3-(3-mesitylureido)-2-naphthamido)cyclohexanecarboxylic acid
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C28H31N3O4
  1
1
IC50 = 1390 nM
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CP0349091
 Compound Info 
(S)-2-(3-(3-mesitylureido)-2-naphthamido)-4-methylpentanoic acid
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C27H31N3O4
  1
1
IC50 = 1427 nM
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CP0514562
 Compound Info 
2-(3-(3-mesitylureido)-2-naphthamido)heptanoic acid
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C28H33N3O4
  1
1
IC50 = 1533 nM
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CP0316922
 Compound Info 
(S)-2-cyclohexyl-2-(2-(2-(2,6-dichlorophenyl)acetamido)-2-naphthamido)acetic acid
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C27H26Cl2N2O4
  1
1
IC50 = 1600 nM
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CP0434852
 Compound Info 
(2S,3R)-3-(tert-butoxy)-2-[(2-{[(2,4,6-trimethylphenyl)carbamoyl]amino}phenyl)formamido]butanoic acid
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C25H33N3O5
  1
1
IC50 = 1680 nM
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CP0333755
 Compound Info 
(S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)-2-(thiophen-2-yl)acetic acid
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C25H20ClN3O4S
  1
1
IC50 = 1700 nM
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CP0349064
 Compound Info 
1-(3-(3-mesitylureido)-2-naphthamido)cyclopentanecarboxylic acid
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C27H29N3O4
  1
1
IC50 = 1773 nM
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CP0491350
 Compound Info 
(2S,3R)-3-(tert-butoxy)-2-[(4-fluoro-2-{[(2,4,6-trimethylphenyl)carbamoyl]amino}phenyl)formamido]butanoic acid
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C25H32FN3O5
  1
1
IC50 = 1820 nM
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CP0333754
 Compound Info 
(2S,3R)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)-3-hydroxybutanoic acid
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C23H22ClN3O5
  1
1
IC50 = 1900 nM
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CP0285685
 Compound Info 
6,6,6-trifluoro-2-(3-(3-mesitylureido)-2-naphthamido)hexanoic acid
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C27H28F3N3O4
  1
1
IC50 = 2003 nM
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CP0317035
 Compound Info 
2-(3-(3-mesitylureido)-2-naphthamido)-2-(1,4-dioxaspiro[4.5]decan-8-yl)acetic acid
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C31H35N3O6
  1
1
IC50 = 2053 nM
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CP0091052
 Compound Info 
(S)-2-((1s,4R)-4-tert-butylcyclohexyl)-2-(3-(3-(2,4,6-trichlorophenyl)ureido)-2-naphthamido)acetic acid
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C30H32Cl3N3O4
  1
1
IC50 = 2400 nM
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CP0163479
 Compound Info 
(2S,3R)-2-(3-(3-mesitylureido)-2-naphthamido)-3-methoxybutanoic acid
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C26H29N3O5
  1
1
IC50 = 2457 nM
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CP0333757
 Compound Info 
(S)-2-((S)-carboxy(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)methylamino)-3-(1H-indol-2-yl)propanoic acid
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C32H28ClN5O6
  1
1
IC50 = 2500 nM
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CP0091056
 Compound Info 
2-(3-(3-mesitylureido)-2-naphthamido)-2-propylpentanoic acid
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C29H35N3O4
  1
1
IC50 = 2517 nM
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CP0040696
 Compound Info 
(S)-1-((S)-carboxy(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)methyl)pyrrolidine-2-carboxylic acid
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C26H25ClN4O6
  1
1
IC50 = 2900 nM
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CP0236331
 Compound Info 
(S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)-3-(4-hydroxyphenyl)propanoic acid
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C28H24ClN3O5
  1
1
IC50 = 3000 nM
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CP0170097
 Compound Info 
(S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)-4-methylpentanoic acid
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C25H26ClN3O4
  1
1
IC50 = 3300 nM
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CP0270705
 Compound Info 
(S)-3-ethoxy-2-(3-(3-mesitylureido)-2-naphthamido)propanoic acid
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C26H29N3O5
  1
1
IC50 = 4467 nM
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CP0264653
 Compound Info 
(S)-2-cyclohexyl-2-(2-(3-(2,6-diethylphenyl)ureido)-2-naphthamido)acetic acid
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C30H35N3O4
  1
1
IC50 = 4500 nM
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CP0040699
 Compound Info 
(S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)succinic acid
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C23H20ClN3O6
  1
1
IC50 = 4700 nM
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CP0333045
 Compound Info 
2-(3-(3-mesitylureido)-2-naphthamido)-2,3-dihydro-1H-indene-2-carboxylic acid
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C31H29N3O4
  1
1
IC50 = 4788 nM
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CP0237994
 Compound Info 
2-(3-(3-mesitylureido)-2-naphthamido)-2-(tetrahydro-2H-pyran-4-yl)acetic acid
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C28H31N3O5
  1
1
IC50 = 4873 nM
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CP0236329
 Compound Info 
(S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-4,5-difluorobenzamido)-2-cyclohexylacetic acid
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C23H24ClF2N3O4
  1
1
IC50 = 6800 nM
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CP0274957
 Compound Info 
(S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)-3-cyclohexylpropanoic acid
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C28H30ClN3O4
  1
1
IC50 = 7400 nM
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CP0341391
 Compound Info 
(S)-4-amino-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)-4-oxobutanoic acid
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C23H21ClN4O5
  1
1
IC50 = 7400 nM
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CP0472071
 Compound Info 
(2S)-2-cyclohexyl-2-[(2-{[(2,6-dimethylphenyl)carbamoyl]amino}-4-fluorophenyl)formamido]acetic acid
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C24H28FN3O4
  1
1
IC50 = 8260 nM
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CP0237995
 Compound Info 
1-(3-(3-mesitylureido)-2-naphthamido)cyclopropanecarboxylic acid
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C25H25N3O4
  1
1
IC50 = 9023 nM
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CP0091059
 Compound Info 
1-(ethoxycarbonyl)-4-(3-(3-mesitylureido)-2-naphthamido)piperidine-4-carboxylic acid
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C30H34N4O6
  1
1
IC50 > 10000 nM
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CP0199028
 Compound Info 
2-(3-(3-mesitylureido)-2-naphthamido)-2-(4-oxocyclohexyl)acetic acid
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C29H31N3O5
  1
1
IC50 > 10000 nM
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CP0313077
 Compound Info 
(S)-2-(3-(3-mesitylureido)-2-naphthamido)-2-((S)-3-oxocyclohexyl)acetic acid
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C29H31N3O5
  1
1
IC50 > 10000 nM
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CP0236330
 Compound Info 
(S)-6-amino-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)hexanoic acid
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C25H27ClN4O4
  1
1
IC50 > 10000 nM
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CP0417780
 Compound Info 
(S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)pentanedioic acid
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C24H22ClN3O6
  1
1
IC50 > 10000 nM
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CP0094229
 Compound Info 
(S)-2-cyclohexyl-2-(2-(3-o-tolylureido)-2-naphthamido)acetic acid
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C27H29N3O4
  1
1
IC50 > 5000 nM
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CP0219679
 Compound Info 
(S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)benzamido)-2-cyclohexylacetic acid
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C23H26ClN3O4
  1
1
IC50 > 7500 nM
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Biochemical Assays
Compound ID Compound Name Compound Formula
CP0037355
 Compound Info 
(2S)-2-[(3-{[(2-chloro-6-methylphenyl)carbamoyl]amino}naphthalen-2-yl)formamido]-2-cyclohexylacetic acid
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C27H28ClN3O4
  1
1 IC50 = 80 nM
CP0245087
 Compound Info 
(S)-2-cyclohexyl-2-(2-(3-(2,6-dichlorophenyl)ureido)-2-naphthamido)acetic acid
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C26H25Cl2N3O4
  1
1 IC50 = 100 nM
CP0097506
 Compound Info 
5-Chloro-1H-indole-2-carboxylic acid ((1S,2R)-1-benzyl-2-dimethylcarbamoyl-2-hydroxy-ethyl)-amide
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C21H22ClN3O3
  1
1 IC50 = 110 nM
CP0128788
 Compound Info 
(S)-2-(2-(3-(2,6-dimethylphenyl)ureido)-2-naphthamido)succinic acid
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C24H23N3O6
  1
1 IC50 = 120 nM
CP0245086
 Compound Info 
(S)-2-cyclohexyl-2-(2-(3-(2,6-dimethylphenyl)ureido)-2-naphthamido)acetic acid
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C28H31N3O4
  1
1 IC50 = 120 nM
CP0341353
 Compound Info 
(S)-2-(2-(3-(2,6-dichlorophenyl)ureido)-2-naphthamido)succinic acid
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C22H17Cl2N3O6
  1
1 IC50 = 230 nM
CP0333757
 Compound Info 
(S)-2-((S)-carboxy(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)methylamino)-3-(1H-indol-2-yl)propanoic acid
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C32H28ClN5O6
  1
1 IC50 = 270 nM
CP0333756
 Compound Info 
(2S,3S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)-3-methylpentanoic acid
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C25H26ClN3O4
  1
1 IC50 = 280 nM
CP0333755
 Compound Info 
(S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)-2-(thiophen-2-yl)acetic acid
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C25H20ClN3O4S
  1
1 IC50 = 360 nM
CP0040699
 Compound Info 
(S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)succinic acid
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C23H20ClN3O6
  2
1 IC50 = 390 nM
2 IC50 = 1600 nM
CP0341391
 Compound Info 
(S)-4-amino-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)-4-oxobutanoic acid
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C23H21ClN4O5
  1
1 IC50 = 420 nM
CP0333754
 Compound Info 
(2S,3R)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)-3-hydroxybutanoic acid
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C23H22ClN3O5
  1
1 IC50 = 430 nM
CP0236331
 Compound Info 
(S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)-3-(4-hydroxyphenyl)propanoic acid
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C28H24ClN3O5
  1
1 IC50 = 450 nM
CP0040696
 Compound Info 
(S)-1-((S)-carboxy(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)methyl)pyrrolidine-2-carboxylic acid
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C26H25ClN4O6
  1
1 IC50 = 580 nM
CP0264653
 Compound Info 
(S)-2-cyclohexyl-2-(2-(3-(2,6-diethylphenyl)ureido)-2-naphthamido)acetic acid
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C30H35N3O4
  1
1 IC50 = 590 nM
CP0170097
 Compound Info 
(S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)-4-methylpentanoic acid
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C25H26ClN3O4
  1
1 IC50 = 600 nM
CP0417780
 Compound Info 
(S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)pentanedioic acid
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C24H22ClN3O6
  1
1 IC50 = 700 nM
CP0236329
 Compound Info 
(S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-4,5-difluorobenzamido)-2-cyclohexylacetic acid
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C23H24ClF2N3O4
  1
1 IC50 = 860 nM
CP0274957
 Compound Info 
(S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)-3-cyclohexylpropanoic acid
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C28H30ClN3O4
  2
1 IC50 = 2200 nM
2 IC50 = 51000 nM
CP0236330
 Compound Info 
(S)-6-amino-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)hexanoic acid
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C25H27ClN4O4
  1
1 IC50 = 3000 nM
CP0316922
 Compound Info 
(S)-2-cyclohexyl-2-(2-(2-(2,6-dichlorophenyl)acetamido)-2-naphthamido)acetic acid
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C27H26Cl2N2O4
  1
1 IC50 = 6800 nM
CP0094229
 Compound Info 
(S)-2-cyclohexyl-2-(2-(3-o-tolylureido)-2-naphthamido)acetic acid
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C27H29N3O4
  1
1 IC50 = 30000 nM
CP0219679
 Compound Info 
(S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)benzamido)-2-cyclohexylacetic acid
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C23H26ClN3O4
  1
1 IC50 = 100000 nM