General Information of the Compound
Compound ID
CP0441399
Compound Name
(S)-2-cyclohexyl-2-(3-(3-(2,4,6-trichlorophenyl)ureido)-2-naphthamido)acetic acid
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Structure
Formula
C26H24Cl3N3O4
Molecular Weight
548.854
Canonical SMILES
OC(=O)[C@@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(Cl)cc(Cl)cc1Cl)C1CCCCC1
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InChI
InChI=1S/C26H24Cl3N3O4/c27-17-12-19(28)23(20(29)13-17)32-26(36)30-21-11-16-9-5-4-8-15(16)10-18(21)24(33)31-22(25(34)35)14-6-2-1-3-7-14/h4-5,8-14,22H,1-3,6-7H2,(H,31,33)(H,34,35)(H2,30,32,36)/t22-/m0/s1
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InChIKey
CTDGLQDIWIHFIA-QFIPXVFZSA-N
Physicochemical Property
logP
7.2073
Rotatable Bonds
6
Heavy Atom Count
36
Polar Areas
107.53
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
3
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11663969
SID: 16767601
ChEMBL ID
CHEMBL512527
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01561, Glycogen phosphorylase, liver form
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
IC50 = 224 nM
   TI
   LI
   LO
   TS