General Information of the Compound
Compound ID
CP0264653
Compound Name
(S)-2-cyclohexyl-2-(2-(3-(2,6-diethylphenyl)ureido)-2-naphthamido)acetic acid
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Structure
Formula
C30H35N3O4
Molecular Weight
501.627
Canonical SMILES
CCc1cccc(CC)c1NC(=O)Nc1cc2ccccc2cc1C(=O)N[C@@H](C1CCCCC1)C(O)=O
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InChI
InChI=1S/C30H35N3O4/c1-3-19-15-10-16-20(4-2)26(19)33-30(37)31-25-18-23-14-9-8-13-22(23)17-24(25)28(34)32-27(29(35)36)21-11-6-5-7-12-21/h8-10,13-18,21,27H,3-7,11-12H2,1-2H3,(H,32,34)(H,35,36)(H2,31,33,37)/t27-/m0/s1
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InChIKey
PODYTHRPTHUEAJ-MHZLTWQESA-N
Physicochemical Property
logP
6.3719
Rotatable Bonds
8
Heavy Atom Count
37
Polar Areas
107.53
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
3
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44560949
ChEMBL ID
CHEMBL469700
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01561, Glycogen phosphorylase, liver form
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
IC50 = 4500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 590 nM