General Information of the Compound
Compound ID
CP0274957
Compound Name
(S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphthamido)-3-cyclohexylpropanoic acid
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Structure
Formula
C28H30ClN3O4
Molecular Weight
508.018
Canonical SMILES
Cc1cccc(Cl)c1NC(=O)Nc1cc2ccccc2cc1C(=O)N[C@@H](CC1CCCCC1)C(O)=O
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InChI
InChI=1S/C28H30ClN3O4/c1-17-8-7-13-22(29)25(17)32-28(36)31-23-16-20-12-6-5-11-19(20)15-21(23)26(33)30-24(27(34)35)14-18-9-3-2-4-10-18/h5-8,11-13,15-16,18,24H,2-4,9-10,14H2,1H3,(H,30,33)(H,34,35)(H2,31,32,36)/t24-/m0/s1
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InChIKey
UEAKFJHZEFJNCU-DEOSSOPVSA-N
Physicochemical Property
logP
6.59902
Rotatable Bonds
7
Heavy Atom Count
36
Polar Areas
107.53
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
3
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44560741
ChEMBL ID
CHEMBL507762
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01561, Glycogen phosphorylase, liver form
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
IC50 = 7400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2200 nM
2 IC50 = 51000 nM