General Information of the Compound
Compound ID
CP0333045
Compound Name
2-(3-(3-mesitylureido)-2-naphthamido)-2,3-dihydro-1H-indene-2-carboxylic acid
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Structure
Formula
C31H29N3O4
Molecular Weight
507.59
Canonical SMILES
Cc1cc(C)c(NC(=O)Nc2cc3ccccc3cc2C(=O)NC2(Cc3ccccc3C2)C(O)=O)c(C)c1
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InChI
InChI=1S/C31H29N3O4/c1-18-12-19(2)27(20(3)13-18)33-30(38)32-26-15-22-9-5-4-8-21(22)14-25(26)28(35)34-31(29(36)37)16-23-10-6-7-11-24(23)17-31/h4-15H,16-17H2,1-3H3,(H,34,35)(H,36,37)(H2,32,33,38)
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InChIKey
XAXCGSHRQAWXRM-UHFFFAOYSA-N
Physicochemical Property
logP
5.76106
Rotatable Bonds
5
Heavy Atom Count
38
Polar Areas
107.53
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
3
Complexity
38

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11620404
SID: 16723303
ChEMBL ID
CHEMBL481887
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01561, Glycogen phosphorylase, liver form
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
IC50 = 4788 nM
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